Clinical trials: Weight Management
Obesity
Exercise Training and Fitness in Severe Obesity
Obesity is commonly associated with insulin resistance and hyperinsulinemia, which seem to be linked with an impaired ability to oxidize lipids, particularly in class III obese individuals [Body Mass Index (BMI): > 40 kg*m-2].
- Trial name
- INTFMOBE (NCT02254200)
- Testing
- Fatmax group, HIIT group
- Where
- Italy
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Weight Management
Study of GS-4571 in Healthy Participants, Nondiabetic Obese Participants, and Nonobese Participants With Type 2 Diabetes Mellitus (T2DM)
The goal of this clinical study is to learn more about the study drug, GS-4571, and how safe it is in 3 groups, i) Healthy participants, ii) Healthy non-diabetic obese participants, and iii) Non-obese participants with Type 2…
- Trial name
- NCT06562907
- Testing
- GS-4571, Omeprazole
- Where
- 3 sites in United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Gilead Sciences
Obesity
Managing Obesity by Combining Behavioral Weight Loss and Commercial Approaches
The purpose of this study is to examine the effectiveness of 3 behavioral weight loss programs- Weight Watchers, university-based behavioral weight loss treatment, and a combined approach which includes university-based treatment…
- Trial name
- NCT00827593
- Testing
- Standard behavioral weight loss treatment, Weight Watchers, Combined Treatment
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Baruch College City University of New York
Obesity
Individualized Lifestyle Intervention for Obesity Management Based on Obesity Phenotypes
The purpose of this protocol is to define an "individualized diet" approach based on obesity related phenotypes (pathophysiology obesity classification), which would increase weight loss, adherence, and weight loss maintenance.
- Trial name
- NCT04073394
- Testing
- Standard Lifestyle Intervention, Modified Lifestyle Intervention
- Where
- United States
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Obesity
Sleep Deprivation and Energy Balance
Observational and epidemiological studies have found a link between obesity and short sleep duration with the prevalence of both increasing in the past decades.
- Trial name
- Sleep (NCT00935402)
- Testing
- Sleep
- Where
- 3 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Satiety
Effects of Mixed Nut Consumption on Satiety and Weight Management
The first goal of the proposed study is to determine acute and long-term effects of mixed nuts (almonds, hazelnuts, pecans, pistachios, walnuts, and peanuts) on metabolic parameters and weight management.
- Trial name
- NCT03375866
- Testing
- Pretzels, Mixed nuts
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Weight Change, Body, Behavior, Health
Increased Monitoring of Physical Activity and Calories With Technology
Since severe obesity in youth has been steadily increasing. Specialized pediatric obesity clinics provide programs to aid in reducing obesity.
- Conditions
- Weight Change, Body, Behavior, Health, Obesity, Childhood, Parent-Child Relations
- Trial name
- IMPACT (NCT03961061)
- Testing
- Brenner mFIT (standard care), Brenner mFIT (standard care plus mobile health components)
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Metabolic Health, Weight Management
A Clinical Trial to Evaluate the Effects of A Supplement on Supporting Signs of Metabolic Health
This study evaluates the effects of the Love Wellness supplement Hello Burn Activate on supporting metabolic health in adult females.
- Conditions
- Metabolic Health, Weight Management, Body Confidence, Gut Health
- Trial name
- NCT07765394
- Testing
- Hello Burn Activate
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Love Wellness
Obesity
Child Health Initiative for Lifelong Eating and Exercise (CHILE)
Child Health Initiative for Lifelong Eating and Exercise (CHILE) is a trans-community multidisciplinary site-specific intervention and evaluation plan for a Head Start and family-based culturally and developmentally appropriate…
- Trial name
- CHILE (NCT00428805)
- Testing
- classroom curriculum, In-service training for Head Start teachers/aides, Training for Head Start food service
- Where
- United States
- Volunteers
- 980 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Insulin Sensitivity, Overweight or Obesity
Pulses Consumption and Its Role in Managing Systemic Inflammation, Insulin Sensitivity and Gut Microbiome in Human
Objective 1: Characterize indices of systemic inflammation and gut microbiota composition and function after chronic (12 weeks) intake of pulses compared to control diet in human OW/OB-IR participants.
- Conditions
- Insulin Sensitivity, Overweight or Obesity, Inflammatory Response
- Trial name
- PS (NCT04267705)
- Testing
- Control, Black bean, Chickpea
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Obesity
Long-term Exercise, Weight Loss and Energy Balance
In order to examine potential gender differences in the weight loss response to exercise, the investigators propose to compare equal energy expenditure of exercise for overweight men and women using levels of exercise energy…
- Trial name
- NCT01186523
- Testing
- Long Term Energy Balance
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- University of Kansas
Obesity
Integrated Obesity Care Management System
Obesity is an important public health problem that is taking epidemic proportions worldwide. Indeed, nearly 50% of Canadians are obese and their number has increased dramatically in the last 20 years.
- Trial name
- NCT01385397
- Testing
- Preceptorship and virtual community
- Where
- Canada
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Pregnancy, Body Weight Changes
Targeting Pregnancy-related Weight Gain to Reduce Disparities in Obesity
The purpose of this study is to find out whether a technology-base healthy lifestyle program is an acceptable and effective way for African-American mothers to improve their eating and activity during pregnancy, compared to usual…
- Conditions
- Pregnancy, Body Weight Changes, Behavioral, Obesity
- Trial name
- NCT02229708
- Testing
- Healthy Lifestyle Group
- Where
- United States
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Temple University
Obesity, Lifestyle
MicroFIBERgut: Effects of Lifestyle Changes and Chitosan on Gut Microbiota and Weight Management
The purpose of this study is to compare the effects of chitosan diet supplementation to a placebo supplement on changes in gut microbiota, body weight and different health parameters among different population groups, being…
- Trial name
- NCT04551365
- Testing
- Lifestyle changes, Chitosan
- Where
- Iceland
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Iceland
Childhood Obesity
Healthy Families: Transforming Care for Obese Children at NYU Lutheran Family Health Centers
Childhood obesity is a contributing factor to health complications such as diabetes, heart disease, high blood pressure, cancer and asthma.
- Trial name
- NCT02817009
- Testing
- Social Support, Nutrition Session, Physical Activity Session
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Weight Loss
Evaluation of Efficacy of a Cashew Apple Extract on Weight Management and Associated Metabolic Risk Factors in Overweight/Obese Volunteers
The purpose of this study is to assess the efficacy and safety of a cashew apple extract on weight management and associated metabolic risk factors in overweight/obese volunteers, versus placebo, after 12 weeks of treatment.
- Trial name
- NCT02493140
- Testing
- Cashew apple extract (Cashewin)
- Where
- France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Dialpha
Weight Loss
Impact of Volunteer Peer-Led Intervention for Weight Control in Primary Care
The specific objective of this research proposal is to determine the short-term efficacy of a primary care-based weight control intervention in which successful volunteer peers deliver a group-based program.
- Trial name
- KL2 (NCT01850550)
- Testing
- Weight loss Groups
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Obesity, Women
Lactobacillus Gasseri and Hormonal Regulation in Obese Women
To evaluate the regulatory effect of Lactobacillus gasseri LG08 formula on visceral fat metabolism and sex hormone balance in obese women.
- Trial name
- NCT07502404
- Testing
- Probiotic, Maltodextrin
- Where
- China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Obesity, Exercise Reinforcement
Exercise and Weight Control
The objective of this project is to determine the biological, neurobehavioral, and behavioral compensatory responses to exercise training-induced energy deficits in overweight to obese men and women.
- Trial name
- NCT03413826
- Testing
- Exercise
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Kentucky
Weight Management
Tolerance and Appetite Reduction of a Nutritional Solution With Intragastric Gelation Properties
The physical properties of a food product, such as its gelling properties in the stomach can influence how full a person may feel after its consumption.
- Trial name
- NCT07127198
- Testing
- Beverage Variant 1 (low gelation properties), Beverage Variant 2 (medium gelation properties), Beverage Variant 3 (high gelation properties)
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)