Clinical trials: Weight Reduction
Weight Loss
Evaluation of a Commercial Program on Weight Loss and Health Outcomes 2
There is a body of evidence that has evaluated the effect of Weight Watchers, a commercially available weight loss program, on changes in body weight.
- Trial name
- NCT03079128
- Testing
- Intervention
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Obesity
Improving Dietary Habit and Weight Loss in Young Adults With Overweight and Obesity: The Healthy Eating for Young Adults (HEYA) Study
This study aims to examining the effectiveness of a psychoeducational program (Healthy Eating in Young Adults; HEYA) on improving the dietary habits and body composition (e.g.
- Trial name
- NCT05969639
- Testing
- HEYA
- Where
- Singapore
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National University Health System, Singapore
Obesity
Reduction of Abdominal Obesity and Insulin Resistance in Women
The purpose of the study was to assess the effects of equivalent diet- or exercise-induced weight loss and related insulin resistance in abdominally obese women.
- Trial name
- NCT00664495
- Testing
- Diet Weight Loss, Exercise Weight Loss, Exercise Without Weight Loss
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Queen's University
Obesity
Craving and Lifestyle Management Through Mindfulness Pilot Study
The purpose of this study is to determine whether an innovative program that combines mindfulness-based stress reduction and mindful eating practices with diet and exercise guidelines (CALMM+ intervention) will lead to greater…
- Trial name
- CALMM (NCT00643344)
- Testing
- Craving and Lifestyle Management through Mindfulness(CALMM+)
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Overweight
Probiotics for Weight Loss
This study will investigate a compound of probiotics and prebiotics in females and males with overweight with the aim to evaluate the effect on weight and metabolic markers.
- Trial name
- NCT04897698
- Testing
- LB001
- Where
- Sweden
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Obesity, Sarcopenia
Biological Effects of Weight Loss In Older, Obese Women
Obesity and sedentary lifestyle are associated with physical impairments and biological changes in older adults. Weight loss combined with exercise may reduce inflammation and may improve physical functioning in older adults who…
- Trial name
- WL+E (NCT01032733)
- Testing
- Lifestyle Counseling, Educational Control
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Florida
Overweight and Obesity, Weight Loss
Pilot Study on Weight Loss With Robotic Assistance
The purpose of this study is to determine whether robotic assistance can help facilitate adherence, engagement, and weight loss in participants enrolled in a behavioral weight loss program.
- Trial name
- NCT03314415
- Testing
- Aldebaraan Nao H25
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Tufts University
Body Weight Changes
Pre Competition Weight Loss of Athletes
The objective of this observational study is to assess the long-term impact of a combined slow and rapid weight reduction strategy on the physiological performance, mental state, and sleep quality of male freestyle wrestlers.
- Trial name
- NCT06543017
- Testing
- Experimental group
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Chengdu Sport University
Diabetes, Obesity
Healthy Eating and Active Living Taught at Home
The purpose of this research study is to evaluate two different Parents as Teachers curriculums taught by parent educators, during home visits.
- Trial name
- HEALTH (NCT01567033)
- Testing
- PAT Curriculum + Health Information
- Where
- United States
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Obesity, Physical Activity
Reducing Television Viewing To Prevent Obesity in Hispanic Preschool Children
Obesity has been linked to the development of multiple cancers, and to poorer prognoses and higher mortality rates for certain pediatric and adult cancers.
- Conditions
- Obesity, Physical Activity, Sedentary Activity, Television Viewing
- Trial name
- NCT01216306
- Testing
- Television reduction curriculum
- Where
- United States
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Obesity, Oxidative Stress
Investigations of Botanicals on Food Intake, Satiety, Weight Loss, and Oxidative Stress
Despite widespread efforts to improve the treatment of obesity, only limited progress has been made. Calorie restriction (CR) has consistently been shown to produce weight loss, as well as delay the onset of age-related diseases…
- Trial name
- NCT01238887
- Testing
- Garcinia cambogia-derived hydroxycitric acid (2800 mg/day), Garcinia Cambogia derived Hydroxycitric Acid
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Florida
Obesity
Changes in Sexual Function Following Bariatric Surgery
The main purposes of the study are to compare changes in sexual function, changes in sex hormones, and changes in body image and marital satisfaction at 12, 24, 36 and 48 months postoperatively in two groups: individuals who…
- Trial name
- NCT00670098
- Testing
- Bariatric surgery, lifestyle intervention (behavioral weight loss)
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Overweight and Obesity, Signs and Symptoms
Implications of Self-weighing During Weight Loss Treatment
This study aims to analyze the effectiveness of introducing behavioral elements in a weight loss program, in this case, comparing the difference between self-weighing versus not doing so.
- Conditions
- Overweight and Obesity, Signs and Symptoms, Behavior, Eating
- Trial name
- NCT04032249
- Testing
- Control Group (CG), Intervention Group (IG)
- Where
- Spain
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universidad de Córdoba
Overweight, Obesity
The Effects of Including Almonds in a Weight Loss Trial
The purpose of this study is to determine whether inclusion of almonds in a weight loss regimen will augment the rate of weight loss, promote a greater fat mass/fat-free mass ratio of weight loss, improve blood pressure and…
- Trial name
- NCT02360787
- Testing
- Energy restriction, Almonds (15% kcal/day)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Purdue University
Obesity, Severe, Pediatric Obesity
Weight Loss With Meal-Replacement Therapy in Teens
This study seeks to examine whether meal-replacement therapy is able to enhance weight loss among teens with severe obesity. In addition, we are also interested in examining the degree of weight loss needed to improve important…
- Trial name
- NCT03137433
- Testing
- Meal-replacement Therapy
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Obesity
Diet Induced Weight Loss to Reduce Inflammation in Obese Women
Breast cancer is one of the most frequently seen cancers in the United States. It occurs at all ages but is particularly common in post menopausal women.
- Trial name
- NCT01699906
- Testing
- Diet regimen to induce weight loss
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Rockefeller University
Obesity
ZGN-440 (Beloranib for Subcutaneous Injection) for Treatment of Obesity
The purpose of this study is to assess the Pharmacokinetics/Pharmacodynamics (PK/PD), safety, and effectiveness of multiple subcutaneous doses of Beloranib (ZGN-440).
- Trial name
- NCT01507077
- Testing
- ZGN-440, ZGN-440 sterile diluent
- Where
- Australia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Zafgen, Inc.
Obesity
Genetics, Metabolism and Weight Loss in Older, Obese Veterans
This study is designed to determine whether sequence variation in the lipoprotein lipase (LPQ) gene affects the amount of weight loss and metabolic responses during a hypocaloric diet treatment for overweight and obese (BMI=25-35…
- Trial name
- NCT00018330
- Testing
- Weight Loss
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Overweight, Obesity
Weight Loss Using the Take Shape For Life Program or the Medifast Direct Program Versus a Self-Directed Diet
The study evaluates the effects of two commercially available weight loss programs, the TSFL and the MEDD programs, each compared to a self-directed control diet, on changes in body weight over a 16-week weight loss phase, in…
- Trial name
- NCT02835092
- Testing
- Take Shape For Life Program, Medifast Direct Program, Self-directed Control
- Where
- United States
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Medifast, Inc.
Cholesterol Lowering
Influence of Polyglucosamine L112 on Serum Surrogate Markers of Cholesterol Absorption
Obesity is widespread and the number of overweight people has tripled from 1975 to 2016. According to the WHO (World Health Organisation), 1.9 billion adults worldwide are overweight, of which 650 million are obese.
- Trial name
- NCT05038436
- Testing
- Polyglucosamine L112
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Certmedica International GmbH
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