Clinical trials: Weight Reduction
Obesity
The Effect of Intervention With Probiotic K56 on Body Fat Reduction in Obese Subjects
The aim of the present study was to investigate the effect of intervention with Lactobacillus paracasei K56 on body fat, metabolic risk markers,inflammatory markers and gut microbiota composition in obesity.
- Trial name
- NCT05192811
- Testing
- Lactobacillus paracasei K56
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fudan University
Prediabetes, Weight Loss
Diabetes Prevention Through Genetics, Familial History and Behavior Change
The goal of this clinical trial is to learn if adding a family engagement component to the standard Diabetes Prevention Program (DPP) improves outcomes for adults with prediabetes.
- Trial name
- NCT07815236
- Testing
- LEGACY DPP, DPP
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Morehouse School of Medicine
Obesity, Diabetes
Effect of Pomegranate Extract Intake on Body Composition and Blood Pressure.
Pomegranate has gained widespread popularity since the health effects of the whole fruit, as well as its juices and extracts, have been studied in relation to a variety of chronic conditions such as hypertension, diabetes…
- Conditions
- Obesity, Diabetes, Cardiovascular Disease
- Trial name
- NCT02017132
- Testing
- Pomegranate extract
- Where
- United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Queen Margaret University
Weight Loss
Enhancing Exercise Participation in Overweight Adults
The purpose of this study is to examine whether behavioral strategies implemented during the adoption versus the maintenance periods of weight loss to enhance exercise participation in overweight adults are more effective than a…
- Trial name
- NCT00177476
- Testing
- behavioral weight loss
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Alcohol Drinking, Weight Loss
The Effects of Alcohol Consumption on Central Adiposity
The objective of the proposed study is to enroll women with obesity that will undergo a controlled, energy restricted feeding intervention to test the effects of chronic ethanol consumption on adipose distribution and circulating…
- Conditions
- Alcohol Drinking, Weight Loss, Adiposity, Obesity
- Trial name
- CONSUME (NCT03521817)
- Testing
- Alcohol, No Alcohol
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Weight Loss, Blood Pressure
Feasibility & Implementation of a Plant-Based Weight-Loss Program in an Office-Based Setting
This prospective study aims to assess the feasibility and implementation of a plant-based, weight-loss program in an office setting.
- Conditions
- Weight Loss, Blood Pressure, Lipid Disorder, PreDiabetes
- Trial name
- NCT04091516
- Testing
- Low-fat plant-based diet
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Physicians Committee for Responsible Medicine
Obesity
Randomized Controlled Clinical Trial of Weight Loss Programs in Obese Persons
The purpose of this study is to compare two approaches to a diet and exercise-based weight loss program.
- Trial name
- SHINE (NCT00960414)
- Testing
- SHINE
- Where
- United States
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Obesity, Gliosis, Weight-Loss
A Cohort Study of Weight Loss and Gliosis
Patients and clinicians need better options to prevent the weight regain that almost universally follows a weight loss intervention. In lay terms, a new, higher "set point" seems to occur after people gain weight.
- Trial name
- NCT03578887
- Testing
- Behavioral Weight Loss Program, Roux-en-Y Gastric Bypass or Sleeve Gastrectomy
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of Washington
Obesity, Weight Loss
A Multidisciplinary Weight Loss Program at AUB-MC
The current project aims at evaluating the feasibility and efficacy of a multi-disciplinary weight loss program, using an innovative and simple dietary intervention at the American University of Beirut Medical Center (AUB-MC).
- Trial name
- NCT04194424
- Testing
- Multidisciplinary weight loss program, Standard Care, Metformin Hcl 850Mg Tab
- Where
- Lebanon
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Athletes
Metabolic, Functional and Nutritional Responses to Weight Cycling in Athletes: The WAVE Study
Many elite athletes are submitted to frequent rapid weight loss periods to meet their competition weight category and then experience weight cycling (lowing and gaining weight regularly).
- Trial name
- WAVE (NCT04107545)
- Testing
- athletes
- Where
- France
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Obesity, Hypertension
Feasibility of Integrating Indirect Calorimetry (IC) Technology in Primary Care
The purpose of this study is to evaluate the feasibility of using indirect calorimetry (IC) within a comprehensive weight reduction program.
- Trial name
- NCT00750022
- Testing
- Individualized IC treatment, Usual Care
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Colorado Center for Chronic Care Innovations, Inc.
Physical Activity, Weight Loss
Structuring Financial Incentives to Increase Physical Activity
The purpose of this study is to evaluate the effectiveness of different structures of long term financial incentives on increasing physical activity performed by subjects, as measured by the number of steps walked per day.
- Trial name
- NCT03305172
- Testing
- Financial Incentive
- Where
- Singapore
- Volunteers
- 620 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Bariatric Surgery Patients
The Metabolic and Genetic Drivers of Body Composition Changes Following Weight Loss Surgery
Weight loss surgery is very good at reducing body weight but it can also cause the loss of both muscle and strength. Some patients undergoing weight loss surgery do not achieve their weight loss goals and regain the weight they…
- Trial name
- NCT07178704
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Weight Loss
The Efficacy of Weight-loss Diet Decision-making Based on Initial Gut Metabolic Modules (GMMs)
In recent years, the technology to detect the gut microbiome's function has become increasingly developed. GMMs are tools (GitHub - raeslab/GMMs: A manually curated database of human gut metabolic modules.) for describing…
- Trial name
- NCT06373887
- Testing
- plant-based Low carbohydrate diet, plant-based Low low fat diet
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Overweight and Obesity, Weight Loss
microRNA Testing for Identification of Personalized Weight Management
Certain blood markers are related to one's ability to successfully lose weight by diet and exercise. Currently, the laboratory tests used to measure these blood markers are expensive and time-consuming.
- Trial name
- NCT04217850
- Testing
- 250 kcal Dietary Energy Restriction, Aerobic Exercise
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- North Dakota State University
Obesity
Weight Loss Maintenance of a New Bioactive Compound (Metobes-Long)
The objective of the present study was to investigate the acute and sub-chronic effect of a supplement containing green tea extract, capsaisin, caffeine, tyrosine and calcium or placebo taken t.i.d on thermogenesis, body fat…
- Trial name
- NCT00302276
- Testing
- Metobes-compound
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Obese
Effects of Legumes Consumption on Weight Reduction
This is a 12-week, randomized nutritional intervention study to determine the effect of legumes consumption on body weight in obese subjects.
- Trial name
- NCT04392882
- Testing
- Legume enriched diet group
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Overweight and Obesity
Short Term Effects of Increasing Sleep Duration
A series of studies are proposed to develop an intervention to increase sleep duration and study the effects on eating, exercise, and weight control.
- Trial name
- NCT01428687
- Testing
- Sleep Duration, No change in sleep
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Homeostasis, Metabolism and Nutrition Disorder
Energy Metabolism Profiles Over Weight-loss and Eating Responses
This is an exploratory controlled before-after study, which involves 112 participants, of whom 28 are with normal weight and 84 are overweight or obese.
- Conditions
- Homeostasis, Metabolism and Nutrition Disorder, Healthy, Obesity
- Trial name
- NCT05785221
- Testing
- General lifestyle and nutritional education, Personalized nutritional and lifestyle weight reduction intervention
- Where
- China
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Sciences
Energy Expenditure, Appetite
Evaluation of Metabolism-Boosting Beverages
The purpose of this study is to assess the effect of Metabolism-boosting Beverages (MBB) containing green tea extract with a standardized amount of epigallocatechin gallate (EGCG) and caffeine.
- Trial name
- NCT01029236
- Testing
- Medifast Metabolism-boosting Beverages
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medifast, Inc.
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