Clinical trials: Weight-Bearing
Avascular Necrosis, Acute Lymphoblastic Leukemia
AVN of Weight-Bearing Joints In Patients With Hematologic Malignancies Treated With Dexamethasone Or Prednisone
The primary purpose of this study is to compare the incidence of AVN in children with hematologic malignancies treated with prednisone versus dexamethasone during continuation.
- Trial name
- NCT00719147
- Testing
- MRI, Functional Status and Symptom Questionnaire
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- St. Jude Children's Research Hospital
Revision Total Knee Arthroplasty, Osteoarthritis, Knee
Gut Microbiome in Orthopaedics: Revision Total Knee Arthroplasty
Many patients who receive knee replacement surgery must return for a revision (or repeat) surgery due to ongoing pain, stiffness, infection, or implant loosening.
- Trial name
- GUMBO (NCT06951477)
- Testing
- Revision Total Knee Arthroplasty
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Knee Arthroplasty, Total, Knee Osteoarthritis
Cementless Triathlon 5YR Follow-Up
All artificial joint implants need to be solidly held (fixed) within the bone. Cementless fixation has become a popular method to achieve fixation for total knee replacements where the bone grows directly onto the implanted…
- Conditions
- Knee Arthroplasty, Total, Knee Osteoarthritis, Radiostereometric Analysis
- Trial name
- NCT05877261
- Testing
- Cementless Total Knee Replacement
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Arthritis
Weight-Bearing Tomosynthesis In Evaluation of Foot/AnkIe
This study aims to compare digital tomosynthesis with radiography and weight-bearing CT as an imaging technique to assess arthritis in the foot and ankle.
- Trial name
- NCT02432170
- Testing
- Digital Tomosynthesis of Foot and Ankle
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of Washington
Cerebral Palsy, Osteoporosis
Influence of Verticalization on Bone Mineral Density and Biological Parameters of Bone Remodeling in Children With Severe Cerebral Palsy
Low bone mineral density affects 77% of children with severe cerebral palsy (GMFCS IV \& V) with an increased fracture risk of 4%. One strategy supposed to improve bone mineral density is verticalisation with static devices.
- Conditions
- Cerebral Palsy, Osteoporosis, Bone Mineral Density, Bone Remodeling Disorder
- Trial name
- CPABONE (NCT04761666)
- Where
- France
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Proprioceptive Neuromuscular Facilitation
Effectiveness of a Proprioceptive Neuromuscular Proprioceptive Neuromuscular Facilitation
Introduction: Paddle tennis is a popular sport which can cause lower limb injuries due to impaired flexibility, such as ankle dorsiflexion.
- Trial name
- NCT05872802
- Testing
- eccentric exercises and electrical stimulation, proprioceptive neuromuscular facilitation
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Católica de Ávila
Myocardial Infarction, Diabetes Mellitus, Type 2
Aerobic Training in Post-MI Patients With DPN
Cardiac rehabilitation (CR) is categorized by the American College of Cardiology "class IA recommendation" in the management of patients with cardiovascular disease (CVD) including post-myocardial infarction (MI) patients, who…
- Conditions
- Myocardial Infarction, Diabetes Mellitus, Type 2, Diabetic Peripheral Neuropathy
- Trial name
- NCT03913793
- Testing
- Exercise based-cardiac rehabilitation (EB-CR) program
- Volunteers
- 37 people
- Sponsor
- Yousra Hisham Abdel Fattah
Traumatic Lower Limb Amputation, Fatigue
Effect of Adding Progressive Muscle Relaxation to Physical Therapy Program on Fatigue, Mobility and Stress Among Individuals With Traumatic Lower Limb Amputation in the Gaza Strip
Lower limb amputation is a life-altering condition with profound physical and psychological consequences, including fatigue, impaired mobility, stress, and asymmetrical weight-bearing.
- Conditions
- Traumatic Lower Limb Amputation, Fatigue, Mobility Impairment, Psychological Stress
- Trial name
- PMR-AMP (NCT07139145)
- Testing
- Progressive Muscle Relaxation + Standard Physiotherapy, Standard Physiotherapy
- Where
- Palestinian Territories
- Volunteers
- 60 people
- Sponsor
- Marah Radi
Arthroscopic Knee Surgery, Lower Limb Fractures
Comparison of Gait Parameters Between Floor and Sponge Surfaces and Special Shoes
This study compares the gait pattern of individuals with weight bearing difficulties walking on the floor, a soft surface, or with special shoes (Kyboot).
- Conditions
- Arthroscopic Knee Surgery, Lower Limb Fractures, Back Pain and Asymmetric Gait, Complex Regional Pain Syndrome
- Trial name
- NCT02742376
- Testing
- Soft surface, Floor, Kyboot shoes
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Periprosthetic Fracture Around Prosthetic Joint Implant Knee
Weight-Bearing CT Periprosthetic Distal Knee Fractures
Total knee arthroplasty (TKA), a knee implant surgery, is a treatment for end-stage knee osteoarthritis. In some cases, patients suffer an associated periprosthetic fracture, a broken bone that occurs around the implant of a TKA…
- Trial name
- NCT06525610
- Testing
- Periprosthetic Fracture Knee Repaired CT Scans
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Cardiovascular Disease, Diabetes Mellitus Type 2, Peripheral Vascular Disorder Due to Diabetes Mellitus
Weight Off-loading Training, Cardiovascular Indices, Diabetes
Aims: To evaluate the effectiveness of partial weight-bearing during aerobic exercise training on cardiovascular disease risk and peripheral vascular function in patients with type 2 diabetes mellitus.
- Trial name
- NCT06974422
- Testing
- Partial weight bearing during aerobic exercise training, Full weight bearing during aerobic exercise training, Regular oral anti-diabetic medications.
- Where
- Saudi Arabia
- Volunteers
- 46 people
- Sponsor
- Umm Al-Qura University
Spinal Cord Injuries
Treatment for Chronic Spinal Cord Injury: Surgery With Rehabilitation vs Rehabilitation
The purpose of this study is to investigate the efficacy of surgical decompression/untethering, combined with weight bearing rehabilitation, on neurological recovery following chronic spinal cord injury.
- Trial name
- NCT02663310
- Testing
- Surgery, Rehabilitation
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Kunming Tongren Hospital
Osteoarthritis, Knee
Weightbearing After High Tibial Osteotomy
In this project we want investigate the clinical results after different rehabilitation regimens(Limited or unlimited weightbearing after surgery) in Open-wedge High Tibial Osteotomies.
- Trial name
- NCT00426907
- Testing
- Unlimited postoperative weightbearing
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Bony Weight Bearing Disorder
After Hip Fracture Nailing, Compare Early Weight Bearing as Tolerated (WBAT) Group With Weight Bearing Restriction(WBR)
Purpose: Proximal femur fracture is a major traumatic injury in elderly populations; however, practical postoperative weight-bearing protocols are lacking.
- Trial name
- NCT06329271
- Testing
- Early-Weight bearing
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Obesity
Folic Acid Supplementation in Women of Child Bearing Age
The objective of this study is to identify genes whose expression is potentially modifiable due to changes in folate intake and help delineate mechanisms accounting for the variability in individual response to folic acid…
- Trial name
- FASUPP (NCT01841658)
- Testing
- Folic acid
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Knee Joint Position Sense
Cold Water Immersion Does Not Reduce Knee Joint Position Sense in Healthy Participants: a Randomised Cross-over Trial
The aim of this project is to assess the effect of cold water immersion on knee joint re-positional sense in healthy subjects. Cryotherapy, in the form of cold water immersion, had previously been shown to improve athletic…
- Trial name
- NCT00996398
- Testing
- Tepid water immersion
- Where
- Ireland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Limerick
Total Hip Replacement, Visual Biofeedback
Insole-based Visual Biofeedback for Weight-bearing in Total Hip Replacement
The study investigates the effects of visual biofeedback, based on a sensorized system for the dynamic evaluation of the plantar pressure versus rehabilitation with traditional verbal instructions of the physiotherapist, on…
- Conditions
- Total Hip Replacement, Visual Biofeedback, Weight Bearing
- Trial name
- NCT04268082
- Testing
- Visual biofeedback with the use of sensorized insoles, Standard rehabilitation based on physiotherapist's verbal instructions
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Pavia
Distal Femur Fractures
Early Weight Bearing on Supracondylar Distal Femur Fractures in Elderly Patients
The investigators will be looking at geriatric distal femur fractures. The investigators will prospectively enroll these patients and allow patients to either weight bear as tolerated or limit their weight bearing post…
- Trial name
- NCT02475941
- Testing
- Non Weight bearing, Early Weight Bearing
- Where
- 6 sites in United States
- Volunteers
- 50 people
- Sponsor
- St. Louis University
Ankle Joint Contracture
Effect of Mobilization With Movement on Weight Bearing Ankle Dorsiflexion Range of Motion
Limited ankle range of motion is associated with increased risk for ankle sprains, knee joint dysfunction and injury to the ACL.
- Trial name
- NCT05844072
- Testing
- Mobilization with movement
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Achilles Tendon Rupture, Soft Tissue Injury
Measurement of Mechanical Properties of the Healing Achilles Tendon With or Without Early Weightbearing
The purpose of this study is to measure the mechanical properties of healing Achilles tendons in humans after early controlled weightbearing, compared with a control group in a randomized, single-blinded trial.
- Conditions
- Achilles Tendon Rupture, Soft Tissue Injury, Tendon Injury
- Trial name
- NCT01063465
- Testing
- Early weightbearing
- Where
- Sweden
- Volunteers
- 35 people
- Sponsor
- Linkoeping University