Clinical trials: Well Aging
Glucose Intolerance, Aortic Stiffness
Healthy Aging Through Functional Food
The purpose of this study is to determine whether dietary inducers of glyoxalase 1 are effective in improving metabolic and vascular health.
- Conditions
- Glucose Intolerance, Aortic Stiffness, Vasodilation
- Trial name
- HATFF (NCT02095873)
- Testing
- Glyoxalase 1 (Glo1) inducer
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Warwick
Aging, Quality of Life
Group Acceptance and Commitment Training (ACT) With Healthy Older Adults
The current study aims to explore the impact of a two-session group Acceptance and Commitment Therapy (ACT) intervention compared to an assessment-only control on psychological outcomes in healthy older adults.
- Trial name
- NCT03839329
- Testing
- Acceptance and Commitment Training
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Anne Roche, MA
Frailty, Intrinsic Capacity
Implementation of Decade of Healthy Ageing Action Plan to Screen and Prevent Decline in Intrinsic Capacity in Elders (SPICE) Through Multisectoral Collaboration in Singapore
This study evaluates the implementation of a structured community-based pathway to screen, risk stratify, and prevent decline in intrinsic capacity (IC) among adults aged 60 years and above in Singapore.
- Conditions
- Frailty, Intrinsic Capacity, Lifestyle
- Trial name
- SPICE (NCT07525583)
- Testing
- ICOPE-Based Digital Intrinsic Capacity Monitoring and Triggered Follow-up (SPICE Pathway)
- Where
- Singapore
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Healthy Aging
Mindfulness and Attention Training Intervention to Lower Distractibility in Aging
The goal of this interventional study is to test the efficacy of combined mindfulness meditation training and cognitive training on brain function and cognition in healthy older adults.
- Trial name
- MATILDA (NCT05974605)
- Testing
- MM+HighC
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Aging Well
Gut Health, Inflammation, Hormones
Pilot exploratory study on the effect of a Bifidobacterium breve extract, as VMK223, on plasma inflammatory markers, saliva hormones, gut microbiota and tolerance in females over 50years old.
- Trial name
- NCT04267731
- Testing
- VMK223, Cellulose
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Vemico Ltd.
Healthy Aging, Mobility Limitation
Power Centering for Seniors
Walking difficulties, mobility decline and falls are prevalent among older adults. The incidence of each of these increases with age and the presence of each can negatively affect the quality of life in older adults.
- Conditions
- Healthy Aging, Mobility Limitation, Walking, Difficulty
- Trial name
- PCS (NCT04861831)
- Testing
- Power Centering for Seniors intervention
- Where
- Switzerland
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University Department of Geriatric Medicine FELIX PLATTER
Active Aging Individuals Aged 65 and Over, Aging
Italian Validation of the dNA Scale and Its Correlation With Neurocognitive Variables
The goal of this experimental multicentric intervention study is to validate, in Italian, the dynamic Neurocognitive Adaptation (dNA) Scale, which has already been validated in English, among a healthy elderly population (aged 65…
- Conditions
- Active Aging Individuals Aged 65 and Over, Aging, Mild Cognitive Impairment (MCI), Dementia
- Trial name
- NCT07533084
- Where
- 8 sites in Italy
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- Neuromed IRCCS
Mobility Limitation
BAILA: Being Active, Increasing Latinos Healthy Aging
Investigators propose a randomized controlled trial (RCT) to test the efficacy of the revised 4-month BAILAMOS© program for improving lifestyle PA and health outcomes (physical and cognitive function, self-reported functional…
- Trial name
- BAILA (NCT01988233)
- Testing
- BAILAMOS© Dance Program, Health Education Control Group
- Where
- 12 sites in United States
- Volunteers
- 333 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Health Behavior, Attitude to Health
Innovative Policies for Healthy Aging
In this study, the investigators evaluate an intervention aiming to increase participation and communication of older adults during primary care consultations with their General Practitioner(GP).
- Conditions
- Health Behavior, Attitude to Health, Impaired Health
- Trial name
- IROHLA (NCT02502292)
- Testing
- Fotonovela
- Where
- Germany
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Jacobs University Bremen gGmbH
Older Adults (65 Years and Older), Cognition
Effects of Breathing Exercises on Cognition in Older Adults
The goal of this interventional clinical trial is to investigate the effects of breathing exercises added to balance training on cognitive function in individuals aged 65 years and older.
- Conditions
- Older Adults (65 Years and Older), Cognition, Balance Control in Elderly, Fall Prevention in Healthy Aging
- Trial name
- NCT07505914
- Testing
- Balance Training Program, Inspiratory Muscle Training, Breathing Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Healthy, Osteopenia
Resistance Training and Rapamycin to Enhance Bone Formation in Postmenopausal Women
The aim of the present clinical trial is to examine the effects of everolimus, resistance training, or their combination on bone and muscle health formation in elderly women aged 60-75 years.
- Conditions
- Healthy, Osteopenia, Osteoporosis Risk
- Trial name
- StrongBone (NCT07191353)
- Testing
- Everolimus, Resistance training
- Where
- 2 sites in Denmark
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Sleep Disturbances, Depression
Neurobiological Investigations of Mindfulness, Depression and Sleep Disturbances in Medical Staffs and Community Elders
The research team proposes a multi-year study with the first year focusing on the developmental phase. In this initial phase, we aim to recruit 40 participants (including healthcare staff and older adults) from Shuang-Ho Hospital…
- Trial name
- NIMDS (NCT07179172)
- Testing
- Mindfulness-Based Stress Reduction (MBSR) 8-Week Program
- Where
- Taiwan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Aging
Role of Flavanols In Cardiovascular Function in Healthy Aging
Groups of naturally occurring compounds called flavonoids are found in foods such as fruits and vegetables, red wine, tea, dark chocolate and cocoa products.
- Trial name
- NCT01395277
- Testing
- High Flavanol first then Low Flavanol, Low Flavanol first then High Flavanol
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Healthy Aging
Modulating the Locus Coeruleus Function
The purpose of this study is to investigate the impact of transcutaneous vagus nerve stimulation (tVNS) on specific brain regions involved in memory and attention processes.
- Trial name
- NCT04877782
- Testing
- Transcutaneous vagus verne stimulation
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Healthy Aging, Brain Health
Assessing the Influence of Habitual Beef Intake on Key Molecular Markers of Brain Health
his study investigates whether eating lean beef every day can help support brain health and healthy aging in older adults. As people age, protecting memory and cognitive function becomes increasingly important.
- Conditions
- Healthy Aging, Brain Health, Cardiometabolic Health, Normal Aging
- Trial name
- NCT07623785
- Testing
- Lean Beef, Non-Beef Control
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- South Dakota State University
Cognitive Change, Mood
Turmeric for Memory Impairment and Cognition
The objective of the study is to test the capacity of acute and chronic supplementations of Turmipure GOLD® to improve cognitive performance in healthy aging
- Conditions
- Cognitive Change, Mood, Stress
- Trial name
- TURMEMIC (NCT04860050)
- Testing
- Turmipure Gold®
- Where
- Ireland
- Volunteers
- 568 people, healthy volunteers welcome
- Sponsor
- Givaudan France Naturals
Mild Cognitive Impairment, Cognitive Decline
Disease Modifying Potential of 5mg of Melatonin on Cognition and Brain Health in Aging
The study will examine whether 5mg melatonin (over the counter, OTC) over a 9-month period improves Alzheimer's disease (AD) biomarkers and cognitive function in two groups of individuals: those with mild cognitive impairment…
- Conditions
- Mild Cognitive Impairment, Cognitive Decline, Healthy Aging
- Trial name
- NCT03954899
- Testing
- melatonin
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Natalie Denburg
Healthy Aging, Fall
Modified Otago Exercise Program on Balance Performance
Fall is a common problem encountered by elderlies. In Hong Kong, the prevalence rate of falls among elderlies aged above 65 years old ranged from 18%-29%, standing at approximately one-fifths of the total elderly population.
- Trial name
- NCT05290571
- Testing
- Modified Otago Exercise Program with music, Modified Otago Exercise Program
- Where
- Hong Kong
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Tung Wah College
Healthy Aging
A Pharmacokinetic Study of a Novel Nutritional Product on Healthy Men and Women
This study is a randomized, double-blind, placebo-controlled study of N=16 apparently healthy men and women. The purpose of this study is to examine the bioavailability of a health and wellness supplement.
- Trial name
- NCT06316700
- Testing
- Nutritional supplement
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Athletic Greens International
Chronic Lymphocytic Leukemia
Characterization of Proliferating Compartment in B-Cell Patients and in Healthy Aging Subjects
By ingesting a non-radioactive and non-toxic compound "heavy water" for 6 weeks, the DNA of newly developed cells in the body of subjects with B-cell chronic lymphocytic leukemia can be labeled and followed by performing routine…
- Trial name
- NCT01110863
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Northwell Health