Clinical trials: Whipple Procedure
Periampullary Cancer, Pancreatic Fistula
Complication of Pancreatic Fistula and Bleeding After Pancreaticoduodenectomy in Treatment Periampullary Cancer
This multi-site study will be done across Hepatobiliary and Pancreatic Surgery Department at Cho Ray Hospital and University and Pharmacy Center.
- Conditions
- Periampullary Cancer, Pancreatic Fistula, Bleeding
- Trial name
- PF (NCT04985071)
- Testing
- Pancreaticoduodenectomy
- Where
- Vietnam
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Vo Truong Quoc
Functional Recovery, Laparoscopy
Comparison of Functional Recovery Between Laparoscopic and Open Pancreaticoduodenectomy
Laparoscopic surgery has not changed much in safety compared with open surgery through many existing studies, and has become a procedure to help patients' recovery.
- Conditions
- Functional Recovery, Laparoscopy, Periampullary Cancer
- Trial name
- NCT03870698
- Testing
- Laparoscopic group
- Where
- South Korea
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Pancreatectomy; Hyperglycemia, Diabete Mellitus
Glucose Metabolism After Partial Pancreatectomy
This is a single center observational study to assess alteration of glucose metabolism after pancreatectomy.
- Trial name
- NCT04409171
- Testing
- oral glucose tolerance test
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Hospital Stay
Effect of Incentive Spirometer and Pursed Lip Breathing After Whipple Procedure.
Whipple procedure is one of the most complex surgeries among hepatobiliary surgeries. It has named as Pancreaticoduodenectomy. It can cause many PPCs. Lung volumes are reduced due to atelectasis and pneumonia.
- Trial name
- NCT06460584
- Testing
- Pursed Lip Breathing, Incentive Spirometer
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Pancreatic Cancer, Adult, Margin, Tumor-Free
Usefulness of the Artery First Approach in Pancreatic Cancer Surgery
This study is aimed to evaluate difference of the 2 year recurrence free survival after pancreaticoduodenectomy for pancreatic cancer between artery-first approach and conventional procedure groups.
- Conditions
- Pancreatic Cancer, Adult, Margin, Tumor-Free, Surgery Site Fistula, Recurrence Tumor
- Trial name
- NCT04136522
- Testing
- conventional pancreaticoduodenectomy, total mesopancreas excision including superior mesenteric artery first approach
- Where
- South Korea
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Distal Cholangiocarcinoma
Minimally Invasive Pancreatoduodenectomy for Distal Cholangiocarcinoma
Outcomes for minimally invasive and open pancreatoduodenectomy for distal cholangiocarcinoma have not been compared. This is an international multicenter propensity score matched cohort study including patients after MIPD or OPD…
- Trial name
- NCT05478889
- Testing
- Minimally invasive pancreatoduodenectomy
- Where
- Italy
- Volunteers
- 478 people, healthy volunteers welcome
- Sponsor
- Fondazione Poliambulanza Istituto Ospedaliero
Pancreas Neoplasm, Neuroendocrine Tumors
Portal Vein Resection in Pancreatic Neuroendocrine Tumours
The limited evidence on the value of portal vein resection in patients with borderline resectable and/or locally advanced PanNENs is an incentive to carry out a retrospective multicentre study amongst centres with specific…
- Trial name
- PVNET (NCT04336839)
- Testing
- Portal vein resection / reconstruction
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Royal Free Hospital NHS Foundation Trust
Pancreatic Cancer
Resection of the Nerve Plexus on the Right Half of Celiac and SMA Associated With Extended Pancreatoduodenectomy in the Surgical Treatment for Adenocarcinoma of the Head of Pancreas
This study is performed to confirm whether resection of the nerve plexus on the right half of celiac and SMA associated with extended pancreatoduodenectomy could improve survival and relieve pain of pancreatic cancer patients.
- Trial name
- NCT02514928
- Testing
- resection of the nerve plexus on the right half of celiac and SMA associated with extended pancreatoduodenectomy, standard pancreatoduodenectomy
- Where
- China
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Fudan University
Enhanced Recovery After Surgery, Mortality
Impact of Anesthesia-related Enhanced Recovery After Surgery Components on Mortality After Pancreaticoduodenectomy
Pancreaticoduodenectomy (PD), one of the most complex and invasive abdominal surgeries, is associated with long length of stay (LOS) and high morbidity and mortality rates.
- Trial name
- NCT06256133
- Testing
- Enhanced Recovery After Surgery protocol
- Where
- South Korea
- Volunteers
- 355 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Pancreaticoduodenectomy, Delayed Gastric Emptying
Comparison Between Pylorus-resecting and Preserving Pancreaticoduodenectomy on Delayed Gastric Emptying and Nutrition
Pylorus preserving pancreaticoduodenectomy has been standard procedure for periampullary benign and malignant disease. Delayed gastric emptying is one of most common complications after the procedure.
- Conditions
- Pancreaticoduodenectomy, Delayed Gastric Emptying, Nutrition
- Trial name
- NCT05314244
- Testing
- Pylorus resecting pancreaticoduodenectomy
- Volunteers
- 394 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Pancreaticoduodenectomy, Pancreatic Fistula
Intravenous Human Albumin In Improving Pancreaticoduodenectomy Outcomes
Pancreaticoduodenectomy (PD), more commonly known as Whipple's surgery is the mainstay treatment for pancreatic head and periampullary cancer.
- Conditions
- Pancreaticoduodenectomy, Pancreatic Fistula, Delayed Gastric Emptying, Pancreatic Cancer
- Trial name
- NCT04418739
- Testing
- Human albumin
- Where
- Malaysia
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Auricular Acupoint Embedding, Pancreaticoduodenectomy
Ear Acupuncture Preventing Delayed Gastric Emptying.
Pancreatoduodenectomy is the preferred surgical method for periampullary diseases. The most common complication is gastric emptying disorder, which often greatly affects the quality of life of patients and prolongs the length of…
- Conditions
- Auricular Acupoint Embedding, Pancreaticoduodenectomy, Delayed Gastric Emptying
- Trial name
- NCT04118881
- Testing
- Ear Acupuncture
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Esophageal Neoplasms, Stomach Neoplasms
The Effect of Satiety Gut Hormone Modulation on Appetitive Drive After Upper Gastrointestinal Surgery
Improvements to treatment strategies for patients with cancers of the upper gastrointestinal tract have produced a large population of people who remain free from cancer recurrence in the long term following treatment.
- Conditions
- Esophageal Neoplasms, Stomach Neoplasms, Weight Loss, Malnutrition
- Trial name
- NCT02381249
- Testing
- Octreotide
- Where
- 2 sites in Ireland, Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- St. James's Hospital, Ireland
Pancreatic Cancer, Microbiota
Characteristics of Intestinal Microbiome Following Pancreatic Surgery
The goal of this observational study is to learn about intestinal microbiome structure and function in individuals who have undergone a pancreatoduodenectomy and compare to healthy matched controls.
- Conditions
- Pancreatic Cancer, Microbiota, Pancreatoduodenectomy
- Trial name
- NCT06319755
- Where
- Australia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Royal Prince Alfred Hospital, Sydney, Australia
Periampullary Neoplasms, Pancreatic Cancer
Cohort Study on Nutritional, Metabolic, and Volumetric Assessment After Pancreaticoduodenectomy
Periampullary malignant neoplasms are among the most lethal gastrointestinal tumors. They are usually diagnosed at advanced stages and require complex surgical treatment.
- Conditions
- Periampullary Neoplasms, Pancreatic Cancer, Pancreaticoduodenectomy
- Trial name
- NCT07159672
- Testing
- Pancreaticoduodenectomy
- Where
- Brazil
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Marco Aurélio Ribeiro, PhD
Disease of Pancreatic Head or Periampullary Lesions to Require Pancreaticoduodenectomy
Predictive Risk Factors for Pancreatic Fistula Grade C After Pancreaticoduodenectomy
Pancreatic fistula (PF) grade C, defined by the International Study Group of Pancreatic Fistula (ISGPF) is associated with a life-threatening complication after pancreaticoduodenectomy(PD).
- Trial name
- NCT02322424
- Testing
- pancreaticoduodenectomy
- Where
- Taiwan
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Wakayama Medical University