Clinical trials: Whipple Procedure
Surgical Technique
Impact of Side to Side Gastrojejunostomy on the Rate of Delayed Gastric Emptying After Pancreaticoduodenectomy (IPAD)
Prospective bi-centric randomized open-label study comparing side to side and end to side gastrojejunostomy in pancreaticoduodenectomy
- Trial name
- IPAD (NCT04742166)
- Testing
- Reconstruction
- Where
- 2 sites in France
- Volunteers
- 166 people
- Sponsor
- Rennes University Hospital
Patients Undergoing Minimally Invasive Pylorus Preserving Pancreaticoduodenectomy
Association of Preoperative Sarcopenia and Intraoperative Hypotension in Patients Undergoing Minimally Invasive Pylorus Preserving Pancreaticoduodenectomy : Prospective Observational Study
The aim of this study is to determine whether preoperative sarcopenia (low muscle strength/muscle mass) is correlated with time weighted average intraoperative hypotension in patients undergoing minimally invasive pylorus…
- Trial name
- NCT05320978
- Testing
- Hand grip test, computed tomography
- Where
- South Korea
- Volunteers
- 192 people
- Sponsor
- Yonsei University
Pancreatoduodenectomy
Efficacy of Rectal Indomethacin in Prevention of Post-operative Pancreatitis After Pancreaticoduodenectomy
Pancreatico-duodenectomy is one of the commonly performed procedure for periampullary/distal cholangio/head of pancreas carcinoma.
- Trial name
- NCT05109143
- Testing
- Indomethacin suppository, Standard Medical Treatment
- Where
- India
- Volunteers
- 44 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Pancreatic Anastomotic Leak
Comparative Study Between Duct to Mucosa and Invagination Pancreaticojejunostomy After Pancreaticoduodenectomy:
Postoperative pancreatic fistula (POPF) remains a challenge even at specialized centers, and also affect significantly the surgical outcomes .
- Trial name
- PJ (NCT02142517)
- Testing
- Duct to mucosa PJ group, Invagination PJ group
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Mansoura University
Pancreatic Neoplasms, Bile Duct Carcinoma
Whipple Procedure: Standard of Care vs. Thunderbeat
The Whipple procedure is the standard method for therapy for cancerous tumors, inflammation, and stenosis (narrowing) near the head of the pancreas.
- Trial name
- NCT02204124
- Testing
- Thunderbeat, Standard of care scissors, ligatures, clips, and sutures
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Washington University School of Medicine
Esophagectomy, Pancreaticoduodenectomy
Preoperative Nutritional Support in Esophagectomy or Pancreaticoduodenectomy
We are proposing to evaluate the benefit of preoperative nutritional support with Impact Advanced Recovery in the most vulnerable group of elective gastrointestinal surgery patients who may experience a complication, esophagus…
- Trial name
- NCT00585624
- Testing
- Impact Advanced Recovery, No supplement
- Where
- United States
- Volunteers
- 344 people
- Sponsor
- University of Wisconsin, Madison
Pancreatic Fistula, Pancreaticoduodenectomy
Prevention of Postoperative Pancreatic Fistula Following Pancreaticoduodenectomy by Preoperative Radiotherapy : a Phase 2 Trial
Design of the study Prospective, single arm, multicentric, phase II open trial Number of participating sites 14 French centers of HPB Surgery departments associated with 14 Radiation Oncology Departments.
- Trial name
- PreFiR (NCT07370987)
- Testing
- Stereotactic radiotherapy / pancreaticoduodenectomy
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pancreatic Cancer, Pancreatic Surgery
Effect of Surgeon Volume on Outcome of Pancreaticoduodenectomy
The independent impact of surgeon volume on outcome of patients undergoing pancreaticoduodenectomy in a high-volume Institution was assessed.
- Trial name
- NCT01059097
- Testing
- Pancreaticoduodenectomy
- Where
- Italy
- Volunteers
- 610 people
- Sponsor
- Università Vita-Salute San Raffaele
Obstructive Jaundice, Pancreatic Head Cancer
Impact of Intraoperative PTCD Catheter Retention Versus Removal on Postoperative Short-term Outcomes After Pancreaticoduodenectomy in Obstructive Jaundice
Pancreaticoduodenectomy (PD) is a complex surgical procedure commonly performed for tumors of the pancreatic head and periampullary region.
- Conditions
- Obstructive Jaundice, Pancreatic Head Cancer, Periampullary Neoplasms, Biliary Tract Neoplasms
- Trial name
- NCT07532759
- Testing
- PTCD Catheter Removal, PTCD Catheter Retention
- Volunteers
- 100 people
- Sponsor
- Xu'an Wang
Cancer of Pancreas, Cancer of Duodenum
Enteral Nutrition After Pancreaticoduodenectomy
Pancreaticoduodenectomy (PD) is the treatment of choice for resectable periampullary cancer. PD is still associated with a relatively a high incidence of delayed gastric emptying.
- Conditions
- Cancer of Pancreas, Cancer of Duodenum, Ampulla of Vater Cancer, Cholangiocarcinoma
- Trial name
- NCT03150615
- Testing
- Early enteral nutrition, Saline, nasojejunal tube insertion
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Nanjing Medical University
Pancreatic Adenocarcinoma
The DISSECT Study: Effect of Peri-aDventItial SMA diSsECtion on Margin sTatus During Pancreaticoduodenectomy for Resectable Pancreatic Cancer
There is a high rate of R1 resection following patients undergoing pancreaticoduodenectomy for pancreatic cancer. The most commonly positive margin is the SMA.
- Trial name
- NCT04902352
- Testing
- No Periadventitial dissection of the SMA, Periadventitial dissection of the SMA
- Where
- United Kingdom
- Volunteers
- 102 people
- Sponsor
- University Hospital Birmingham NHS Foundation Trust
Pancreatic Disease
Outcomes in Minimally Invasive Versus Open Pancreaticoduodenectomy
The purpose of this study is to evaluate the impact of the quality of life in patients undergoing the Whipple procedure (pancreaticoduodenectomy, PD) for pancreatic cancer.
- Trial name
- NCT02638818
- Testing
- minimally invasive pancreaticoduodenectomy, traditional pancreaticoduodenectomy
- Volunteers
- 57 people
- Sponsor
- Duke University
Surgery-Complications
Textbook and Survival Outcomes of MIPD in South Korea
The aim of this study was to investigate the current status of minimally invasive pancreatoduodenectomy (MIPD) in South Korea with regard to demographics, perioperative outcomes, risk factors for textbook outcome of pancreatic…
- Trial name
- NCT05975710
- Where
- South Korea
- Volunteers
- 1,552 people
- Sponsor
- Asan Medical Center
Pancreatic Fistula
Isolated Roux Loop Versus Conventional Pancreaticojejunostomy Following Pancreaticoduodenectomy
Pancreaticoduodenectomy is a commonly applied operation for the treatment of benign and malignant diseases of periampullary region.
- Trial name
- NCT03671031
- Testing
- isolated roux loop, single loop
- Where
- Turkey (Türkiye)
- Volunteers
- 109 people
- Sponsor
- Inonu University
Vascular Resection, Pancreatic Cancer
Vascular Resection in Robotic Pancreaticoduodenectomy for Pancreatic Cancer
Data for this propensity score-matched (PSM) comparative study were obtained from a prospectively maintained database comprising 679 cases of robotic pancreaticoduodenectomy (RPD).
- Conditions
- Vascular Resection, Pancreatic Cancer, Robotic Pancreaticoduodenectomy
- Trial name
- VR in RPD (NCT07871045)
- Testing
- vascular resection
- Where
- Taiwan
- Volunteers
- 239 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Intra Abdominal Pressure, Abdominal Compartment Syndrome
Intra-abdominal Hypertension and Abdominal Compartment Syndrome in Patients After Pancreatic Procedures.
This study investigates the development of intra-abdominal hypertension and compartment syndrome in patients undergoing elective pancreatic procedures.
- Conditions
- Intra Abdominal Pressure, Abdominal Compartment Syndrome, Pancreatic Surgery, Pancreatic Fistula After Pancreaticoduodenectomy
- Trial name
- HYPA (NCT06672601)
- Where
- Czechia
- Volunteers
- 150 people
- Sponsor
- Charles University, Czech Republic
Pancreaticoduodenectomy
Paravertebral Block vs no Block in Open Pancreaticoduodenectomy
The purpose of this study is to compare intra and postoperative pain control between Paravertebral block vs no block in open pancreaticoduodenectomy. Length of stay, and complications will also be recorded.
- Trial name
- NCT05820997
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Mayo Clinic
Pancreatic Carcinoma
Accelerated Recovery Pathway for Discharge After Surgery in Patients With Pancreatic Cancer
This randomized clinical trial studies accelerated recovery pathway for discharge after surgery in patients with pancreatic cancer.
- Trial name
- WARP (NCT02517268)
- Testing
- Pancreaticoduodenectomy
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Pancreas Cancer
Preoperative CA 19.9 Level Predicts Lymph Node Metastasis in Resectable Adenocarcinoma of the Head of the Pancreas.
In our multicenter retrospective study, preoperative CA 19.9 levels predicts the presence of lymph node metastasis at final histology in patients underwent pancreatoduodenectomy for pancreatic ductal adenocarcinoma .
- Trial name
- ICALYRA (NCT05959213)
- Volunteers
- 2,034 people
- Sponsor
- Fondazione Policlinico Universitario Campus Bio-Medico
Tumors
Reduced Pancreatic Fistula Rate Following Pancreaticoduodenectomy: Trial on Pancreaticogastrostomy Versus Pancreaticojejunostomy
The incidence of complications after pancreaticoduodenectomy (PD) is around 50 %. The postoperative course after PD is strongly dependent of the occurrence of pancreatic fistula (POPF), which determines postoperative mortality…
- Trial name
- NCT00830778
- Testing
- Pancreaticojejunostomy, Pancreaticogastrostomy
- Where
- Belgium
- Volunteers
- 336 people
- Sponsor
- Baki Topal