Clinical trials: Whipple Procedure
Pancreatic Head Cancer Patients Who Underwent Surgery After Neoadjuvant Treatment
Clinical Outcomes of Preservation Versus Resection of Portal/Superior Mesenteric Vein During Pancreaticoduodenectomy in Pancreatic Cancer Patients Who Respond to Neoadjuvant Treatment
1. There is a lack of evidence on the need to perform portal/superior mesenteric vein (PV/SMV) resection routinely in pancreatic ductal adenocarcinoma (PDAC) patients with venous involvement who responded to neoadjuvant treatment…
- Trial name
- NCT06372886
- Testing
- portal/superior vein resection
- Volunteers
- 264 people
- Sponsor
- Seoul National University Hospital
Periampullary Neoplasms, Pancreatic Cancer
Total Pancreatectomy With Islet Autotransplantation (TPIAT) for High-Risk Patients With Pancreatic Tumors
This is a single-center, prospective, single-arm feasibility study evaluating whether adult patients with periampullary neoplasms who are at high risk for postoperative pancreatic fistula after pancreaticoduodenectomy can be…
- Conditions
- Periampullary Neoplasms, Pancreatic Cancer, Pancreatic Neoplasms
- Trial name
- NCT07360119
- Testing
- Total Pancreatectomy with Islet Autotransplantation (TPIAT)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Pancreatic Head Cancer, Obstructive Jaundice
Endoscopic Versus Percutaneous Biliary Drainage for Resectable Pancreatic Head Cancer
Patients with potentially resectable pancreatic head cancer and high bilirubin level, were stratified into two equal groups according to the method of biliary drainage: endoscopic stenting or percutaneous drainage.
- Trial name
- NCT04823832
- Testing
- pancreaticoduodenectomy
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Hani Alhadad
Morbidity, Celiac Axis Stenosis
The Effect of Celiac Axis Stenosis on Morbidity After Pancreatoduodenectomy - A Prospective Study
The association between celiac axis stenosis and morbidity after pancreaticoduodenectomy is the primary focus of the study.
- Conditions
- Morbidity, Celiac Axis Stenosis, Pancreaticoduodenectomy, Pancreatic Cancer
- Trial name
- NCT07412301
- Where
- Greece
- Volunteers
- 99 people
- Sponsor
- Larissa University Hospital
Pancreaticoduodenal; Fistula, Surgery Timing
Effects of Surgical Timing on Perioperative Clinical Outcomes in Pancreaticoduodenectomy
With the advancement of surgical techniques and the increase in pancreatic oncologic diseases, the volume of pancreaticoduodenal surgeries has been increasing year by year in our center, and multiple pancreaticoduodenal surgeries…
- Conditions
- Pancreaticoduodenal; Fistula, Surgery Timing, Perioperative Complication
- Trial name
- NCT06874660
- Where
- China
- Volunteers
- 350 people
- Sponsor
- West China Hospital
Pancreatic Cancer, Bile Duct Cancer
The Comparison of Miniinvasive and Open Pancreaticoduodenectomy for Cancer Pancreaticobiliary Zone
The Comparison of Miniinvasive and Open Pancreaticoduodenectomy for Cancer Pancreaticobiliary Zone
- Conditions
- Pancreatic Cancer, Bile Duct Cancer, Ampulla of Vater Cancer
- Trial name
- NCT04763642
- Testing
- pancreaticoduodenectomy
- Where
- Russia
- Volunteers
- 320 people
- Sponsor
- State Budget Public Health Institution Scientific Research Institute - Ochapovsky Regional Clinical Hospital
Pancreatic Fistula, Pancreas Neoplasm
Biodegradable Pancreatic Stents for the Prevention of Postoperative Pancreatic Fistula After Cephalic Pancreaticoduodenectomy
Background: postoperative pancreatic fistula (POPF) remains the most important morbidity after pancreaticoduodenectomy (PD). There is no consensual technique for pancreatic reconstruction and many surgeons use a transanastomotic…
- Conditions
- Pancreatic Fistula, Pancreas Neoplasm, Stent Disintegration, Pancreatic Cancer
- Trial name
- NCT04783831
- Testing
- Biodegradable stent
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Hospital Universitario Virgen de la Arrixaca
Intraabdominal Abscess After Procedure
Specific Bile Microorganisms Caused Intra-abdominal Abscess on Pancreaticoduodenectomy Patients: Customized Antibiotics And Antifungal Medication May Be Necessary
Background Intra-abdominal abscess (IAA) is one of the most serious surgical infectious complications on pancreaticoduodenectomy (PD) patients.
- Trial name
- NCT05011630
- Testing
- Pancreaticoduodenectomy
- Volunteers
- 539 people
- Sponsor
- National Taiwan University Hospital
Periampullary Cancer, Pancreatic Cancer
Comparison Between Endoscopic Stenting and Cholecystojejunostomy for PreoperativeDrainage Before Pancreaticoduodenectomy
Periampullary carcinoma and carcinoma head of pancreas are common causes of obstruction at the lower end of the common bile duct.
- Trial name
- NCT01913275
- Testing
- Endoscopic stenting, cholecystojejunostomy
- Where
- India
- Sponsor
- All India Institute of Medical Sciences
Pancreatic Neoplasms, Biliary Tract Neoplasms
Nonstented Stump-closed vs Duct-to-Mucosa Pancreaticojejunostomy After Pancreaticoduodenectomy
Pancreaticojejunostomy is the key procedure of pancreaticoduodenectomy. The aim of our study is to investigate a new pancreaticojejunal (PJ) anastomosis procedure named "nonstented stump-closed pancreaticojejunostomy" in…
- Conditions
- Pancreatic Neoplasms, Biliary Tract Neoplasms, Pancreatitis, Chronic, Duodenal Neoplasms
- Trial name
- NCT01731821
- Testing
- pancreaticojejunostomy
- Where
- China
- Volunteers
- 308 people
- Sponsor
- Fudan University
Pancreas Fistula Abdominal Drains
First-day Versus Early Drain Removal Following PD: a Randomized Controlled Trial
Pancreatic surgery is a complex discipline with a high risk of post-operative morbidity such as pancreatic fistula (POPF) with variable impact on clinical outcome.
- Trial name
- FIDEL (NCT06468917)
- Testing
- 1st day removal of abdominal drain
- Where
- Italy
- Volunteers
- 224 people
- Sponsor
- Casa di Cura Dott. Pederzoli
Periampullary Tumor, Complication
RCT Study on Safety of LPD and OPD in the Treatment of Periampullary Tumors
Pancreaticoduodenectomy (PD) is considered one of the most complex and dangerous procedures in general surgery. This procedure is the preferred surgical procedure for treating tumors around the ampulla.
- Conditions
- Periampullary Tumor, Complication, Death, Survival
- Trial name
- NCT04037982
- Testing
- laparoscopic pancreaticoduodenectomy, Open pancreaticoduodenectomy
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Beijing Friendship Hospital
Pancreatic Cancer
Correlation Between Complications After Pancreaticoduodenectomy and Microbiota
Pancreaticoduodenectomy is the most performed pancreatic surgery for malignant or premalignant tumors of the region of the head of the pancreas. Its post-operative morbidity is very high, over 40%.
- Trial name
- COMPAMIC (NCT04931069)
- Testing
- Microbiota analysis
- Where
- France
- Volunteers
- 39 people
- Sponsor
- University Hospital, Toulouse
Pancreaticoduodenectomy, Distal Pancreatectomy
The Novel Modified Cattell-Warren Duct-To-Mucosa Pancreaticojejunostomy Technique Significantly Reduces POPF.
Pancreatic surgeries, such as pancreaticoduodenectomy and distal pancreatectomy, are associated with high morbidity and mortality. The most common cause of this morbidity is postoperative pancreatic fistula(POPF).
- Conditions
- Pancreaticoduodenectomy, Distal Pancreatectomy, Postoperative Pancreatic Fistula
- Trial name
- POPF (NCT07038161)
- Testing
- Modified Cattell-Warren duct-to-mucosa pancreaticojejunostomy, Institutional Prehabilitation Protocol
- Where
- Nepal
- Volunteers
- 27 people
- Sponsor
- Nepal Medical College and Teaching Hospital
Pancreatic Fistula
One-layer Versus Two-layer Duct-to-mucosa Pancreaticojejunostomy After Pancreaticoduodenectomy .
Postoperative pancreatic fistula (POPF) is one of the most frequent and ominous complications after PD, and its occurrence reportedly ranges from 2-40 %.
- Trial name
- NCT05387538
- Testing
- One-layer Duct-to-mucosa Pancreaticojejunostomy, Two-layer Duct-to-mucosa Pancreaticojejunostomy
- Volunteers
- 50 people
- Sponsor
- Assiut University
Periampullary Tumor
The Effect of ERAS on Pancreaticoduodenectomy
Enhanced Recovery After Surgery (ERAS) is not the program that aim to reduce postoperative hospital stay, but the multimodal strategies that aim to attenuate the loss of, and improve the restoration of,functional capacity after…
- Trial name
- ERAS (NCT02372331)
- Testing
- ERAS perioperative management
- Where
- South Korea
- Volunteers
- 276 people
- Sponsor
- Asan Medical Center
Pancreatic Neoplasms, Pancreaticoduodenectomy
Benchmarking Outcomes in Pancreatic Surgery - WhippleBenchmarks.Org
The WhippleBenchmark 2 Collaborative study aims at defining benchmark criteria for best achievable outcomes after pancreaticoduodenectomy with portal vein resection.
- Trial name
- NCT04053998
- Testing
- Pancreaticoduodenectomy with portal vein resection
- Where
- 2 sites in Spain, United Kingdom
- Volunteers
- 1,462 people
- Sponsor
- Royal Free Hospital NHS Foundation Trust
Postoperative Pancreatic Fistula
A Study on the Occurrence Time of Grade-B Pancreatic Fistula After Pancreatoduodenectomy
To confirm the time point of CR-POPF of grade-B that patients with biochemical leak after PD or LPD turned into.
- Trial name
- NCT05667272
- Testing
- No intervention
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Changzhou Second People's Hospital affiliated with Nanjing Medical University
Pancreas Cancer, Bile Duct Cancer
Early Enteral Feeding After Pylorus Preserving Pancreatoduodenectomy
Pancreaticoduodenectomy is associated with a high incidence of postoperative complications. These postoperative complications could delay postoperative resumption of adequate oral intake.
- Conditions
- Pancreas Cancer, Bile Duct Cancer, Ampulla of Vater Cancer
- Trial name
- NCT00809081
- Testing
- Enteral Feeding and Total Parental Support
- Where
- South Korea
- Volunteers
- 38 people
- Sponsor
- Yonsei University
Pancreatic and Periampullary Tumors
Pancreatoduodenectomy in Pancreatic and Periampullary Tumors
Background: Recently it has been observed in pancreatic cancer that after apparently complete surgical resection, histological examination of the surgical specimen according to a standard protocol reveals tumor infiltration of…
- Trial name
- DUOPAN-EPAM (NCT02803814)
- Testing
- Superior mesenteric artery approach for pancreatoduodenectomy, Classic approach for pancreatoduodenectomy
- Where
- Spain
- Volunteers
- 154 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia