Clinical trials: White Spot Lesion of Tooth
White Spot Lesion of Tooth
Reminerlization Potential of Innovative Biomimetic Material in Caries White Spot Lesions
to remineralize the white spot caries lesions after orthodontic treatment , the investigator will use two different materials ( Clinpro tooth creme versus Gc tooth mousse) and will compare between their effects in…
- Trial name
- NCT03823612
- Testing
- Clinpro Tooth Creme, GC tooth mousse
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cairo University
White Spot Lesion of Tooth
Effect of Different Pastes on Remineralization of Early Caries Lesions in Primary Teeth
This study is a randomized controlled trial involving 118 children ages between 4 and 5 years to assess the remineralization effect of Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP) on white spot lesions in primary…
- Trial name
- NCT03526276
- Testing
- CPP-ACP paste, Fluoride toothpaste, Both (Fluoride and CPP-ACP)
- Where
- Jordan
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Dental Caries, White Spot Lesion
A Randomized Controlled Trial of Vitamin D Supplementation on Salivary Biomarkers and Cariogenic Oral Microbiome
The goal of this clinical trial is to compare the treatment effect of vitamin D supplementation and topical fluorides in the population having vitamin D deficiency and Initial Carious Lesions (ICL) on the progression of ICL in…
- Conditions
- Dental Caries, White Spot Lesion, Initial Caries, Incipient Enamel Caries
- Trial name
- Incipient (NCT06172764)
- Testing
- Vitamin D supplements along with behavioral modification, Topical fluoride application and Vitamin D supplements along with behavioral modification, Topical fluoride application along with behavioral modification
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
White Spot Lesions, Dental Plaque
AI-Generated WhatsApp Reminders vs. No Reminders: Impact on Oral Health in Young Adults
This randomized controlled trial aims to evaluate the effectiveness of artificial intelligence-generated WhatsApp reminders on improving oral hygiene practices among individuals aged 20-40 years visiting the periodontal clinic at…
- Conditions
- White Spot Lesions, Dental Plaque, Oral Hygiene, Oral Health
- Trial name
- NCT06897033
- Testing
- Health education followed by AI-generated Whatsapp reminders, Oral Health Education
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental White Spots
Enamel Damages Following De-bracketing From Infiltrated Surfaces
Demineralisation and white-spot caries often occures during MB treatment. While resin infiltration has been proved to stop progression of enamel demineralisation, there is still a paucity of information in the literature…
- Trial name
- NCT02359318
- Testing
- Resin infiltration, Bonding and debonding of brackets.
- Where
- Chile
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- DMG Dental Material Gesellschaft mbH
White Spot Lesion of Tooth, Tooth Color
Toothpastes With Different Contents and Tooth Color
This study aims to investigate the color tone and fluorescence changes that may occur during fixed orthodontic treatment with brackets in patients' teeth using toothpaste with different properties.
- Conditions
- White Spot Lesion of Tooth, Tooth Color, Dentistry, Orthodontic Appliances, Fixed
- Trial name
- NCT06833970
- Testing
- Colgate use, Curaprox use, ROCS use
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Taner OZTURK, DDS, MS
Initial Caries
Early Detection of Initial Caries Using Fluorescent Starch Nano-particles Compared With Salivary Biomarkers
Dental caries is one of the most prevalent chronic oral diseases worldwide and remains a major public health concern. The disease begins with microscopic demineralization of enamel, which is reversible if diagnosed at an early…
- Trial name
- NCT07732127
- Testing
- Fluorescent Starch Nano-particles
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Tooth Demineralization
Study of Treatments Used for White Spot Lesions After Orthodontic Treatment.
The purpose of this study is to learn more about the management of white spot lesions that occur after orthodontic treatment. White spot lesions generally improve slightly with time.
- Trial name
- NCT01059058
- Testing
- MI Paste Plus, PreviDent Fluoride Varnish, Normal Home Care
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Washington
White Spot Lesion of Tooth
Combined Application of Diode Laser and Different Remineralizing Agents on White Spot Lesions
Dental caries is a very common condition, and although it has become less common, it still represents a serious public health risk.
- Trial name
- Whitespot (NCT05871619)
- Testing
- Remin Pro, X Pur Remin, Fluoride varnish
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
White Spot Lesion, Enamel Hypomineralization
Evaluation of CPP-ACP Prophylactic Effect on Enamel Surface During Orthodontic Treatment
This study is aiming in preventing the formation of WSL associated with orthodontic treatment which occurs to more than 50% of orthodontically treated patients through applying CPP-ACP on the enamel surface once every 2 weeks for…
- Trial name
- NCT03187548
- Testing
- Casein Phosphopeptide-Amorphous Calcium Phosphate Dental Paste
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cairo University
White Spot Lesion
Remineralization Effect Of Egg Shell Versus Fluoride Varnish On Early Carious White Spot Lesions In Primary Teeth
The goal of this clinical trial is to to assess the remineralization potential of Egg shell hydrogel versus fluoride varnish in early carious white spot lesions in anterior primary teeth.
- Trial name
- NCT06932926
- Testing
- Egg shell hydrogel, Fluoride varnish
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
The Prevalence of White Spot Lesions During Orthodontic Treatment With Fixed Appliances
This study investigates how often cavities develop on the permanent teeth of patients with braces (orthodontic treatment). The hypothesis is that there is no difference in the number of cavities on the permanent teeth of patients…
- Trial name
- WSLs (NCT04186065)
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Hiroko Nagaoka
Dental Caries, Streptococcus Mutans
Effect of MI Paste Plus™ on Streptococcus Mutans and White Spot Lesions in Fixed Orthodontics
Background This study is part of a doctoral research project at Universidad Cardenal Herrera CEU (Spain), directed by Prof. Santiago Arias de Luxán and conducted by doctoral candidate Shirli Kelmendi within the PhD program in…
- Conditions
- Dental Caries, Streptococcus Mutans, Tooth Demineralization, Orthodontic Appliances, Fixed
- Trial name
- MIPASTEORTHO (NCT07244991)
- Testing
- MI Paste Plus (CPP-ACP with Sodium Fluoride)
- Where
- 2 sites in Albania
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cardenal Herrera University
Dental Caries
Prevention of Enamel Demineralization by Use of K18-smooth Surface Sealant
This study will evaluate effectiveness of a urethane dimethacrylate (UDMA)-quaternary ammonium methacrylate (K18) resin (UDMA-K18) smooth surface sealant to prevent biofilm attachment to tooth surfaces thereby eliminating the…
- Trial name
- K18 (NCT03306433)
- Testing
- UDMA-K18 smooth surface sealant
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Initial Dental Caries
Dentifrice With Innovative Remineralizing Technology
Objective: The aim of this study is to evaluate in vivo dentifrices containing different active ingredients in fluoride (F) retention in saliva and dental biofilm.
- Trial name
- REFIX (NCT04730908)
- Testing
- DENTIFRICE
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federal University of Paraíba
White Spot Lesion of Tooth
Remineralizing Effect of Different Silver-containing Agents on Initial Caries Lesions in Primary Teeth in Children
The aim of the present work is to study the effect of the application of Silver diamine fluoride (SDF) and a novel green synthesized Nano-silver fluoride (NSF) on early enamel lesions in primary teeth.
- Trial name
- NCT06489093
- Testing
- NSF, SDF+KI, Control group
- Where
- Bulgaria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Plovdiv Medical University
White Spot Lesion
Fluoride Controlled-release System for Initial Lesions of Caries
OBJECTIVE: To evaluate in vivo the efficacy of fluoride-containing dentifrice incorporated in a controlled-release system (F-CSL, patent pending) in the remineralization of white spot lesions of caries in caries-active…
- Trial name
- NCT05139966
- Testing
- Mouthwash Product
- Where
- Brazil
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Federal University of Paraíba
White Spot Lesions [Initial Caries] on Smooth Surface of Tooth
Effectiveness of Different Toothpastes in Treating White Spot Lesions
This randomized clinical trial and laboratory study was conducted to: Compare the effectiveness of zinc-carbonated nano-hydroxyapatite, arginine, and fluoride-containing toothpastes for treating white spot lesions associated with…
- Trial name
- NCT06128434
- Testing
- zinc carbonate nano-hydroxyapatite toothpaste, 8% arginine toothpaste, Fluoride toothpaste
- Where
- Egypt
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Dental Caries
Remineralization Effect of Eggshell Powder on Post-orthodontic White Spot Lesions Compared to CPP-ACP
This research is conducted to compare the remineralization efficacy of eggshell powder gel and CPP-ACP (MI paste) on post-orthodontic white spot lesions.
- Trial name
- REEPP-WSC (NCT03963791)
- Testing
- Eggshell powder gel, CPP-ACP crème
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Reminerlization Potential of GSE Gel versusCPP-ACP in Carious White Spot Lesions in Post Orthodontic Patients
Assess the effectiveness of applying grape seed extract (GSE) gel versus casein phosphopeptide-amorphous calcium phosphate (MI) paste on remineralization of white spot lesion (WSLs) in post orthodontic patients.
- Trial name
- NCT03966378
- Testing
- Grape seeds extract, Casein-phosphopeptide/amorphous-calcium phosphate
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University