Clinical trials: Winter Depression
Seasonal Affective Disorder
A Trial of Negative Ion Generation Versus Light-Emitting Diode Phototherapy for Seasonal Affective Disorder (SAD)
This is a randomized, controlled clinical trial of inactivated negative ion generation or light-emitting photodiode therapy for Seasonal Affective Disorder (SAD, winter depression), for subjects with a DSM IV diagnosis of Major…
- Trial name
- NCT00809523
- Testing
- Negative Ion Generator, Light-emitting Photodiode light treatment device
- Where
- 8 sites in United States, Canada and 1 more
- Volunteers
- 106 people
- Sponsor
- Yale University
Depression
Predicting Effectiveness of Light Treatment for Winter Seasonal Affective Disorder
This study will evaluate a possible tool for predicting future effectiveness of bright light in treating seasonal affective disorder, winter subtype, and will examine secondary effects of bright light on cardiovascular risk…
- Trial name
- NCT00742365
- Testing
- Bright light
- Volunteers
- 41 people
- Sponsor
- University of Maryland, Baltimore
Seasonal Affective Disorder
Optimizing Long-Term Outcomes for Winter Depression With CBT-SAD and Light Therapy
Major depression is a highly prevalent, chronic, and debilitating mental health problem with significant social cost that poses a tremendous economic burden.
- Trial name
- NCT03691792
- Testing
- Cognitive-Behavioral Therapy (CBT-SAD), Light Therapy
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- University of Vermont
Depressive Disorder
Seasonal Affective Depression (SAD) Study
A placebo controlled study evaluating the effectiveness of medication in preventing winter depressive episodes in patients with a history of Seasonal Affective Disorder
- Trial name
- NCT00069459
- Testing
- Extended-release Bupropion Hydrochloride
- Where
- 48 sites in United States
- Volunteers
- 250 people
- Sponsor
- GlaxoSmithKline
Seasonal Affective Disorder
Blue Enriched Versus Standard Light Treatment for Seasonal Affective Disorder(SAD)
One of the most frequently investigated hypothesis of the pathophysiology underlying Seasonal Affective Disorder(SAD) or so called winterdepression is a disturbance of circadian rhythms.
- Trial name
- NCT01048294
- Testing
- Original Energy Light,, Original Energy Light prototype
- Where
- Netherlands
- Volunteers
- 52 people
- Sponsor
- University Medical Center Groningen
Seasonal Affective Disorder, Vitamin D3
The Role of Vitamin D Supplementation on Well Being and Symptoms of Depression During the Winter Season in Health Service Staff
The purpose of this study is to investigate whether vitamin D3 (70 micrograms) is better than placebo in preventing depression symptoms among employees in health care
- Conditions
- Seasonal Affective Disorder, Vitamin D3, Mental Health, Dietary Supplement
- Trial name
- D3-vit-SAD (NCT01462058)
- Testing
- Vitamin D3
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Connie Thuree Nielsen, consultant, MD, ph.d
Seasonal Affective Disorder, Healthy
Clinical Trial of Propranolol for Seasonal Affective Disorder
The purpose of this study is to determine what dose of a new timed-release tablet of the drug propranolol will reduce secretion of the hormone melatonin in healthy volunteers.
- Trial name
- NCT00016666
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Seasonal Affective Disorder (SAD), Winter Depression
Cognitive-behavioral Therapy vs. Light Therapy for Preventing SAD Recurrence
Major depression is a highly prevalent, chronic, and debilitating mental health problem with significant social cost that poses a tremendous economic burden.
- Conditions
- Seasonal Affective Disorder (SAD), Winter Depression, Major Depressive Disorder, Recurrent, With Seasonal Pattern
- Trial name
- NCT01714050
- Testing
- Cognitive-Behavioral Therapy (CBT), Light Therapy (LT)
- Where
- United States
- Volunteers
- 177 people
- Sponsor
- University of Vermont
Seasonal Affective Disorder
30-Minute Light Exposure for the Treatment of Seasonal Affective Disorder
The primary objective of this study is to evaluate the effect of light therapy using a narrow 467nm light compared to a 580nm light in subjects with Seasonal Affective Disorder (SAD).
- Trial name
- SAD (NCT01462305)
- Testing
- goLITE, Control
- Where
- 4 sites in United States
- Volunteers
- 35 people
- Sponsor
- Philips Respironics
Seasonal Affective Disorder, Mood Disorders
Clinical Trials of Three Non-Drug Treatments for Winter Depression (SAD)
We are offering non-pharmacologic therapy for alleviation of symptoms associated with depressed mood that recurs annually in fall or winter.
- Conditions
- Seasonal Affective Disorder, Mood Disorders, Depression
- Trial name
- NCT00006517
- Testing
- bright light box, dawn simulator, high-output negative ion generator
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- New York State Psychiatric Institute
Seasonal Affective Disorder
Research Study of Treatment for Winter Depression With Different Colors of Light
The specific aim of this study is to test the hypothesis that light stimuli concentrated around 467 nm will evoke a significantly stronger therapeutic response in SAD patients compared to light stimuli concentrated around 657 nm…
- Trial name
- NCT00269633
- Testing
- Blue Light Box 467 nm, Red Light Box 657 nm
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Thomas Jefferson University
Depression, Unipolar Depression
Effectiveness of Light Therapy Across Seasons
This study investigates whether the antidepressant effects of bright light therapy (BLT) differ between the spring/summer season and the autumn/winter season in adults with depressive disorders.
- Conditions
- Depression, Unipolar Depression, Bipolar Depression Depressed Phase
- Trial name
- NCT07599124
- Testing
- Bright Light Therapy
- Where
- Netherlands
- Volunteers
- 212 people
- Sponsor
- Geestelijke Gezondheidszorg Eindhoven (GGzE)
Seasonal Affective Disorder
Prevention of Seasonal Affective Disorder
This is a placebo controlled study evaluating the effectiveness of medication in preventing depressive episodes in subjects with a history of Seasonal Affective Disorder (SAD).
- Trial name
- NCT00046241
- Testing
- Extended-release bupropion hydrochloride
- Where
- 51 sites in United States, Canada
- Volunteers
- 300 people
- Sponsor
- GlaxoSmithKline
Seasonal Affective Disorder
Study of Genes in Relation to Seasonal Affective Disorder and Major Depressive Disorder
The investigators are looking for volunteers who have a history of Major Depressive Disorder, the Winter Blues, or Seasonal Affective Disorder or healthy volunteers who do not have a history of these disorders for a research…
- Trial name
- Season605 (NCT01292889)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Environmental Exposure, Winter Depression
Health Consequences of Wintering in the French Southern and Antarctic Territories
Polar stays expose people to extreme climate, isolation and confinement. The combination of these factors induces psychological disorders, sleep disorders, immune and endocrine disturbances, and deficiencies.
- Conditions
- Environmental Exposure, Winter Depression, Endocrine System Diseases, Sleep Disorder
- Trial name
- MediTAAF (NCT04768621)
- Testing
- Questionary
- Where
- Reunion
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion