Clinical trials: Withdrawal of Life Support
Intensive Care, Supportive Care
A Prospective Study Evaluating the Feasibility and Ethical Perspective of Maastricht III Organ Procurement in French Intensive Care Unit Patients
The Maastricht III procedure consists of performing organ donation in patients in whom cardiac arrest is consecutive to a decision to withdraw life support.This MIII procedure is not applied in France, in contrast with other…
- Conditions
- Intensive Care, Supportive Care, Withdrawal of Life Support
- Trial name
- MIII (NCT01662375)
- Testing
- Surveillance and interview
- Where
- France
- Volunteers
- 29 people
- Sponsor
- Nantes University Hospital
Palliative Care, Withdrawal of Life Support
End-of-life Care in Mechanically Ventilated Patients: Impact of a Comprehensive Palliative Care Protocol in the Intensive Care Setting
The ARREVE-3 trial will evaluate whether a structured palliative care protocol can improve end-of-life management for mechanically ventilated ICU patients in whom a decision to withdraw life-sustaining therapies has been made.
- Conditions
- Palliative Care, Withdrawal of Life Support, Intensive Care Medicine, Sedation
- Trial name
- ARREVE-3 (NCT07368010)
- Testing
- Protocol for palliative care and life-support withdrawal
- Where
- France
- Volunteers
- 720 people
- Sponsor
- Nantes University Hospital
Death, Assisted, Tissue and Organ Procurement
Experience of Relatives and Intensive Care Units Caregivers of Controlled Donation After Circulatory Death
Controlled donation after circulatory death (cDCD) refers to organ donation (OD) from patients whose death is defined using circulatory criteria and from whom circulatory death occurs after a planned withdrawal of life-sustaining…
- Conditions
- Death, Assisted, Tissue and Organ Procurement, Life Support Care
- Trial name
- CARE-M3 (NCT05041023)
- Testing
- Relative section, Caregiver section
- Where
- France
- Volunteers
- 367 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Opioid Use Disorder, Opioid Withdrawal
Medically Supervised Ibogaine With 12-Month Digital Recovery Support for Opioid Use Disorder
IBO-CARE is a single-site Phase 1/2a study evaluating the safety, tolerability, feasibility and preliminary outcomes of medically supervised ibogaine with 12 months of recovery support in adults with moderate-to-severe opioid use…
- Conditions
- Opioid Use Disorder, Opioid Withdrawal, Substance Use Disorders
- Trial name
- IBO-CARE (NCT07871877)
- Testing
- Ibogaine Hydrochloride, Extended-release naltrexone injection, 380 mg, My-E-Health SENTINEL Digital Monitoring and Human-Gated Escalation Platform
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Clive Michelsen
Stress Disorders, Post-Traumatic
Post Traumatic Stress Among Relatives of Brain-dead, Withdrawal of Life Support, and Sudden Death Patients
This study concerns the nearest relatives of patients who have passed away within 3 days of admission to an ICU due to: (1) brain death with multiple organ donation +/- tissues or (2) death via limitation and / or cessation of…
- Trial name
- NCT01412502
- Testing
- IES-R and HDAS scores
- Where
- 6 sites in France
- Volunteers
- 119 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes