Clinical trials: Wound; Knee
Knee Arthroplasty
First Mobilization Protocol for Total Knee Arthroplasty Patients
This single blinded randomized controlled study evaluates the effect of developed First Mobilization Protocol applied to knee arthroplasty patients on state anxiety, kinesiophobia, initial mobilization related symptoms.
- Trial name
- NCT06268899
- Testing
- First mobilization protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Gazi University
Traumatic; Lesion, Degenerative Lesion of Articular Cartilage of Knee
Randomized Evaluation of BST-CarGel Versus Microfracture Alone On Recovery From Distal Femoral Cartilage Lesions
This multi-centre randomized, controlled trial will assess the impact of BST-CarGel scaffold with microfracture versus microfracture alone on short and long term clinical benefit in patients with cartilage lesions of the femoral…
- Trial name
- RECORD (NCT02981355)
- Testing
- Microfracture treatment, BST-CarGel
- Where
- 15 sites in Australia, Canada and 5 more
- Volunteers
- 5 people
- Sponsor
- Piramal Healthcare Canada Ltd
Knee Dislocation
Knee Dislocation - Clinical Evaluation of the Use of Hinged External Fixator After Ligament Reconstruction
Knee dislocation is a serious injury, usually caused by high-energy trauma. It is classically defined as complete loss of articular congruence between the femur and the tibia, confirmed by radiography.
- Trial name
- NCT02290197
- Testing
- Surgery, Hinged External Fixator, Cast Immobilization
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Lower Extremity Problem, Rehabilitation
Patient-Reported Outcome Measures in Lower Extremity Rehabilitation Program PROM_R: Impact on Health Care
Different musculoskeletal conditions affect people all over the world and were considered by the WHO to be the leading cause of disability in 4 out of 6 regions in 2017, with an increase in the associated burden and impact on…
- Conditions
- Lower Extremity Problem, Rehabilitation, Knee Injuries
- Trial name
- PROM_R (NCT06206018)
- Testing
- PROM_R knee rehabilitation program
- Where
- Portugal
- Volunteers
- 65 people
- Sponsor
- University of Évora
Proximal Tibia Fracture
The Efficacy and Cost Effectiveness of Preoperative and Postoperative Cryotherapy in Proximal Tibia Fractures
Consenting patients with proximal tibia fractures will be randomized to 10 degree or 21 degree cryotherapy sleeves. Time to discharge and complications will be monitored.
- Trial name
- ARCTIC CAT (NCT01104831)
- Testing
- Cryotherapy, Room temperature cuff
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Anterior Cruciate Ligament Injuries, Injuries, Knee
Effects Provided by a Physiotherapy Treatment Preventing Lower Extremity Injuries in Female Football Players
Background and justification: Women's football has a percentage of knee injury of 31.8%, and the anterior cruciate ligament lesion is between 2 and 4 times higher than the male.
- Conditions
- Anterior Cruciate Ligament Injuries, Injuries, Knee, Prevention & Control
- Trial name
- NCT04062578
- Testing
- Physiotherapy program of lumbopelvic stabilization and strengthening of the hip region musculature
- Where
- Spain
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Orthopedic Disorders, Foot Diseases
Efficacy of Ultrasound-Guided Local Anesthetic Injection Into or Around the Sciatic Nerve for Lower Limb Anesthesia
This study was designed to assess whether the injection of local anesthetic into the nerve (intraneural), as opposed to around it (perineural), requires a shorter time to develop surgical anesthesia of the lower leg.
- Conditions
- Orthopedic Disorders, Foot Diseases, Injuries, Leg, Injuries, Foot
- Trial name
- NCT01999647
- Testing
- Intraneural Injection for Subgluteal Sciatic Nerve Block, Perineural Injection for Subgluteal Sciatic Nerve Block, Femoral Nerve Block
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- University of Parma
Peripheral Vascular Disease
Safety/Feasibility Study of HBOC-201 in Amputation at/Below Knee From Critical Lower Limb Ischemia
The purpose of this study is to assess the safety and feasibility of HBOC-201 in increasing adequate wound healing in patients with severe peripheral vascular disease who are undergoing lower limb amputation.
- Trial name
- NCT00300040
- Testing
- Hemoglobin glutamer 250 - bovine, 6% Hydroxyethylstarch
- Where
- 5 sites in South Africa, United Kingdom
- Volunteers
- 16 people
- Sponsor
- Biopure Corporation
Neurologic Diseases, Arthropathy of Knee
Experience of Use and Biopsychosocial Effects of Robotic and Virtual Reality Devices in Neuromotor Rehabilitation
The implementation of virtual reality (VR) and robotic devices in neuromotor rehabilitation has so far provided promising evidence in terms of efficacy throughout different clinical populations.
- Conditions
- Neurologic Diseases, Arthropathy of Knee, Arthropathy of Hip
- Trial name
- NCT05399043
- Testing
- Multidisciplinary Conventional Neuromotor Rehabilitation, Technology-based Rehabilitation
- Where
- Italy
- Volunteers
- 84 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
Arthroscopic ACL Reconstruction: Hamstring Versus Quadriceps
The use of hamstrings and quadriceps autografts as an alternative option for reconstruction of the anterior cruciate ligament has good clinical results: however, both techniques have not been compared among them, which is why…
- Trial name
- NCT04137250
- Testing
- Hamstring, Quadriceps tendon
- Where
- Mexico
- Volunteers
- 28 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Recurrent Patellar Dislocation
Arthroscopic Clinical Study of Double Bundle Anatomical Reconstruction of Medial Patellofemoral Ligament
Objective: To study the clinical effect of double-beam anatomical reconstruction of medial patellofemoral ligament under arthroscopy.
- Trial name
- NCT04456881
- Testing
- Patients with patellar dislocation undergo patellar femoral medial reconstruction
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking University Third Hospital
Phantom Limb Pain, Phantom Pain
VR to Evaluate Phantom Limb Pain
The objective of this study is to develop a virtual rehabilitation system that can be used to effectively treat Phantom Limb Pain (PLP) within the research setting and for at-home use by individuals with upper and lower extremity…
- Conditions
- Phantom Limb Pain, Phantom Pain, Phantom Sensation, Phantom Limb Syndrome With Pain
- Trial name
- NCT05915065
- Testing
- Coapt Phantom Limb Pain Management System
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Shirley Ryan AbilityLab
Patella Dislocation Recurrent, Patellar Dislocation
Clinical Outcomes Following Patellar Dislocation in Young Athletes
The purpose of this study is to identify predictors of future injury and disability following LPD. The investigators' long term goal is to improve longitudinal outcomes of athletes with LPD following surgical and non-surgical…
- Trial name
- NCT03040232
- Testing
- biomechanical assessment
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Osteoarthritis, Knee, Rheumatoid Arthritis of Knee
Evaluation of The Safety And Performance of The Freedom Total Knee® System With The PEEK-OPTIMA Femoral Component
Prospective, multi-centre, non-comparative, post-market surveillance clinical study
- Conditions
- Osteoarthritis, Knee, Rheumatoid Arthritis of Knee, Traumatic Arthritis of Knee (Diagnosis), Polyarthritis
- Trial name
- NCT03224689
- Testing
- PEEK-Optima Femoral Component
- Where
- Belgium
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Maxx Orthopedics Inc
ACL Injury, ACL - Anterior Cruciate Ligament Rupture
Dynamic ACL Brace: In Vivo Kinematics
The purpose of this study is to evaluate the effect of the Össur Rebound dynamic ACL brace on knee kinematics evaluated using dynamic stereo X-ray (DSX) imaging during functional activities.
- Conditions
- ACL Injury, ACL - Anterior Cruciate Ligament Rupture, ACL, ACL - Anterior Cruciate Ligament Deficiency
- Trial name
- NCT03670550
- Testing
- Ossur Rebound ACL Brace
- Where
- United States
- Sponsor
- Steadman Philippon Research Institute
Total Knee Replacement
Comparison of Surgical Site Infection After Skin Closure by Prolene or Staples in Bilateral Knee Arthroplasty Patients
Knee arthroplasty also known as the total knee replacement is an orthopedic surgical procedure done to resurface the knee that has been severely damaged by arthritis.
- Trial name
- NCT04492852
- Testing
- Polypropylene (PROLENE) sutures, Staple Sutures
- Volunteers
- 82 people
- Sponsor
- Indus Hospital and Health Network
Anterior Cruciate Ligament Rupture, Donor Site Complication
BTB Graft Harvest and Donor Site Morbidity After ACL Reconstruction
The aim of this observational study is to examine the connection between bone-tendinous defects after BTB graft harvest and the development of anterior knee pain.
- Trial name
- NCT06030791
- Testing
- MRI
- Where
- Serbia
- Volunteers
- 60 people
- Sponsor
- Clinical Center of Vojvodina
Anterior Cruciate Ligament Rupture
Effect of Tunnel Placements on Clinical and MRI Findings Two Years After ACL Reconstruction With DB Technique
Purpose: To find out whether the clinical and MRI findings two years after anterior cruciate ligament (ACL) reconstruction were associated with each other so that MRI-based graft invisibility in the anteromedial (AM) graft would…
- Trial name
- NCT02000258
- Testing
- Double-bundle ACL reconstruction, Magnetic resonance imaging (MRI)
- Where
- Finland
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Anterior Cruciate Ligament Injuries, Arthroscopy
Functional Outcomes Comparison in Patients Using Knee Brace Post ACL Reconstruction With Autograft Bone Quadricep Tendon
This study is a study looking for the relationship between variables with a prospective cohort design to determine functional outcomes subjectively and objectively in patients with and without braces after ACL reconstruction with…
- Conditions
- Anterior Cruciate Ligament Injuries, Arthroscopy, Braces
- Trial name
- ACL (NCT05457452)
- Testing
- Knee Brace
- Where
- Indonesia
- Volunteers
- 32 people
- Sponsor
- Universitas Indonesia
Medial Meniscus Knee Injury
Evaluation of Different Patterns PHMM Root Tears
1. To evaluate and classify different morphological patterns of posterior horn medial meniscus root tears (PHMMRTs) and assess their correlation with clinical presentation, MRI findings, and arthroscopic features. 2.
- Trial name
- NCT07602985
- Testing
- MRI
- Volunteers
- 30 people
- Sponsor
- Assiut University
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