Clinical trials: Wound; Knee
Osteoarthritis, Knee, Anterior Cruciate Ligament Injuries
Vibration and Post-traumatic Osteoarthritis Risk Following ACL Injury
The goal of this randomized clinical trial is to evaluate the effects of vibration on factors related to the risks of post-traumatic knee osteoarthritis and secondary anterior cruciate ligament (ACL) injury in individuals who…
- Conditions
- Osteoarthritis, Knee, Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis, Quadriceps Muscle Atrophy
- Trial name
- NCT04875052
- Testing
- Experimental: Whole Body Vibration, Experimental: Local Muscle Vibration, Standard ACL Rehabilitation
- Where
- 2 sites in United States
- Volunteers
- 114 people
- Sponsor
- University of North Carolina, Chapel Hill
ACL - Anterior Cruciate Ligament Rupture
Soft-tissue Quadriceps Autograft ACL-reconstruction in the Skeletally-immature vs. Hamstrings
To date, the use of the quadriceps tendon as an autograft option in primary paediatric Anterior Cruciate Ligament (ACL) reconstruction has not been well studied.
- Trial name
- SQuASH (NCT03896464)
- Testing
- Soft tissue hamstring autograft, Quadriceps tendon autograft
- Where
- 6 sites in Canada, Japan
- Volunteers
- 352 people
- Sponsor
- McMaster University
Knee Injuries, Knee Arthritis
Kinematic Parameters to Predict Knee Diseases.
There is no study to explore the prediction of knee diseases using kinematic parameters of knee during gait. The aim of this study is to explore the possibility of predicting knee diseases by gait parameters.
- Trial name
- NCT03130400
- Testing
- Observational gait analysis procedure
- Where
- China
- Volunteers
- 1,914 people, healthy volunteers welcome
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
Meniscus Injury, Knee Osteoarthritis
Knee Arthroscopy Cohort Southern Denmark (KACS)
PURPOSE: To investigate the natural time course of patient-reported outcomes after meniscus surgery and identify factors associated with good and bad outcome after surgery.
- Trial name
- KACS (NCT01871272)
- Testing
- Arthroscopic Meniscus Surgery
- Where
- 4 sites in Denmark
- Volunteers
- 491 people
- Sponsor
- University of Southern Denmark
Ligament Injury
Peroneus Longus Graft :Effect in Foot and Ankle Function
The purpose of this study is to report the ankle and foot functions via American orthopedic foot and ankle society score (AOFAS), peronei muscle testing ,handheld dynamometer and radiological outcomes after harvesting autogenous…
- Trial name
- NCT05991557
- Testing
- peroneus longus autograft
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Anterior Cruciate Ligament Injury, Knee Injury
Optimizing Plyometric Training for Functional Recovery Post-ACL Reconstruction
While surgical anterior cruciate ligament reconstruction (ACLR) of the knee restores passive stability, studies are showing consistently poor long-term outcomes.
- Trial name
- NCT02148172
- Testing
- Standard Plyometric Training, Plyometric Training with BWS
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of Montana
Anterior Cruciate Ligament Injury
ACL SNNAP Trial: ACL Surgery Necessity in Non Acute Patients
The primary objective of this study is to determine in patients with non-acute Anterior Cruciate Ligament Deficiency (ACLD) whether a strategy of non-surgical management [Rehabilitation] (with option for later ACL reconstruction…
- Trial name
- ACL SNNAP (NCT02980367)
- Testing
- Non-Surgical Management (Rehabilitation), Surgical Management (Reconstruction)
- Where
- 32 sites in United Kingdom
- Volunteers
- 320 people
- Sponsor
- University of Oxford
Patellofemoral Dislocation
Assessment of Surgical Correction of Patello-femoral Instability by EOS 3D Kinematics
Assessment of surgical correction of patello-femoral instability by EOS 3D kinematics
- Trial name
- EOS-FP2017 (NCT04143438)
- Testing
- EOS 3D imaging protocol pre- and post-surgery
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Montpellier
ACL Injury
Rehabilitation Treatment of Anterior Cruciate Ligament Rupture
The purpose with this present study is to investigate the effect og a non-surgical regime in patients with an Anterior Cruciate ligament injury.
- Trial name
- NCT04408885
- Testing
- Rehabilitation
- Where
- Denmark
- Volunteers
- 400 people
- Sponsor
- Aarhus University Hospital
Degenerative Lesion of Articular Cartilage of Knee
Microfracture Versus Adipose Derived Stem Cells for the Treatment of Articular Cartilage Defects
The purpose of this study is to compare two biologic methods for the treatment of articular cartilage defects in the knee. The first method, microfracture, is the standard of care and is routinely used to recruit cells from the…
- Trial name
- NCT02090140
- Testing
- ADSC Application, Microfracture
- Where
- 3 sites in United States
- Volunteers
- 17 people
- Sponsor
- University of Colorado, Denver
Anterior Cruciate Ligament Tear
Regenexx™ SD Versus Exercise Therapy for ACL Tears
The primary objective of this study is to compare the improvement in subject-reported clinical outcomes for Regenexx SD vs. Exercise Therapy treatment of partial and complete, non-retracted knee ACL ligament tears, from baseline…
- Trial name
- NCT01850758
- Testing
- Regenexx SD, Exercise Therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Regenexx, LLC
Anterior Cruciate Ligament Injuries
Biologic Therapy to Prevent Osteoarthritis After ACL Injury
Anterior cruciate ligament (ACL) injuries are extremely common. On average, 50% of individuals suffering an ACL injury will develop radiographic osteoarthritis (OA) 10 to 20 years after injury.
- Trial name
- NCT03968913
- Testing
- Anakinra injection, sterile saline injection
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
ACL Injury
Ultrasound-guided Percutaneous Neuromodulation in Anterior Cruciate Reconstruction
The objective of the study is to demonstrate the efficacy of the ultrasound-guided percutaneous neuromodulation technique in the femoral nerve in patients who underwent surgery for the anterior cruciate ligament.
- Trial name
- NMPeLCA (NCT05606250)
- Testing
- Ultrasound-Guided Percutaneous Neuromodulation
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Universidad Europea de Madrid
Anterior Cruciate Ligament Injuries, Anesthesia Injection Site
Ropivacaine and Midazolam by Intraarticular vs Epidural Administration in Arthroscopic ACL
Compare of the effectiveness of the use of ropivacaine and midazolam by intraarticular vs epidural administration on post-operative analgesia after isolated arthroscopic anterior cruciate ligament (ACL) reconstruction with…
- Conditions
- Anterior Cruciate Ligament Injuries, Anesthesia Injection Site, Knee Injuries
- Trial name
- NCT05078372
- Testing
- ropivacaine and midazolam intraarticular administration, ropivacaine and midazolam epidural administration
- Where
- Mexico
- Volunteers
- 108 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Knee Osteoarthritis, Knee Injuries
Clinical Study of Novel Diagnostic Techniques for Knee Osteoarthritis
The purpose of this study is to clarify the potential of intra-articular ultrasound imaging, non-invasive ultrasound imaging, quantitative MRI imaging, contrast-enhanced CT imaging and arthroscopy for diagnostics of knee…
- Trial name
- NCT01359553
- Testing
- Intra-articular ultrasound imaging of knee joint during arthroscopy, Non-invasive ultrasound imaging of knee, Quantitative MRI imaging of knee
- Where
- Finland
- Volunteers
- 12 people
- Sponsor
- University of Oulu
ACL Injury, ACL Augmentation
Augmentation of Partial Anterior Cruciate Ligament Tear: Early Results
Clinical evaluation for the patients with partial ACL tear who had ACL augmentation
- Trial name
- Augmentation (NCT05391672)
- Testing
- we will do ACL augmentation surgery to the patients who have partial ACL tear
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Knee Injuries, Cartilage Injury
Biomaterials and Mesenchymal Stem/Stromal Cells in the Treatment of Knee Articular Surface Lesions
The goal of this observational study is to evaluate the combined single-step approach with biomaterials and mesenchymal stem/stromal cells in the treatment of knee articular surface lesions.
- Conditions
- Knee Injuries, Cartilage Injury, Osteochondral Defect
- Trial name
- NCT06078072
- Testing
- Biomaterials augmented with mesenchymal stem/stromal cells
- Where
- Slovenia
- Volunteers
- 90 people
- Sponsor
- University Medical Centre Ljubljana
ACL Injury
ACL Reconstruction in Patients Aged 50 Years and Older
Anterior cruciate ligament (ACL) injury is one of the most common knee ligament injuries in athletes, and surgical ACL reconstruction is the treatment of choice to allow patients to return to sports and recreational activities.
- Trial name
- LCA Over 50 (NCT07387939)
- Where
- Italy
- Volunteers
- 56 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Knee Osteoarthritis (Knee OA)
Knee OsteoArthritis Long-term Assessment
The goal of this clinical study is to learn if Hydrogel OA 2% injection is safe and whether it works to improve symptoms of diagnosed knee osteoarthritis in adults when compared to Hyaluronic Acid (Durolane), a treatment that is…
- Trial name
- KOALA (NCT06839222)
- Testing
- Hydrogel OA 2%, Hyaluronic Acid (Durolane)
- Where
- 5 sites in Belgium
- Sponsor
- Allegro NV/SA
ACL Injury, Meniscus Lesion
Meniscal Lesions in Return to Sport After Anterior Cruciate Ligament Reconstruction
Most athletes who undergo Anterior Cruciate Ligament Reconstruction (ACLR) plan to return to some level of sporting (RTS) activity.
- Conditions
- ACL Injury, Meniscus Lesion, Sport Injury
- Trial name
- LCA-40 (NCT04129827)
- Testing
- Clinical, self-reported psychological and biomechanical assessments
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Bari
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