Clinical trials: Wound; Knee
Amputation, Surgical, Amputation, Traumatic
Cryoanalgesia to Treat Phantom Limb Pain Following Above-Knee Amputation
When a limb is severed, pain perceived in the part of the body that no longer exists often develops and is called "phantom limb" pain.
- Conditions
- Amputation, Surgical, Amputation, Traumatic, Phantom Limb Pain, Phantom Pain Following Amputation of Lower Limb
- Trial name
- NCT06071715
- Testing
- ACTIVE cryoneurolysis
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of California, San Diego
Spinal Cord Injury
C-Brace II Spinal Cord Injury
A randomized, repeated measures comparative design study to compare use of a micro-processor controlled knee-ankle-foot orthosis vs.
- Trial name
- NCT03930056
- Testing
- C-Brace II, Traditional Care KAFO intervention
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Shirley Ryan AbilityLab
Anterior Cruciate Ligament Injuries
Robotic Assistance for Tunnel Positioning in Anterior Cruciate Ligament Reconstruction
Accurate ideal graft tunnel positioning is essential for the successful application of anatomic anterior cruciate ligament (ACL) reconstruction.
- Trial name
- MIRRACL (NCT04183803)
- Testing
- anatomic anterior cruciate ligament (ACL) reconstruction
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Tear; Knee, Cartilage, Articular
Clinical Trial for the Regeneration of Cartilage Lesions in the Knee
The purpose of this study is to investigate the efficacy of an engineered cartilage transplant (N-TEC) in comparison to a cell-activated matrix (N-CAM) for the treatment of articular cartilage lesions in the knee.
- Trial name
- NosetoKnee2 (NCT02673905)
- Testing
- Tissue Engineered Product
- Where
- 5 sites in Croatia, Germany and 2 more
- Volunteers
- 108 people
- Sponsor
- University Hospital, Basel, Switzerland
Musculoskeletal Injury, Muscle Weakness
The ADAPTation to Therapeutic Resistance Training (ADAPT) Study
In 2018, the Academic Department of Military Rehabilitation (ADMR) published a pilot randomised controlled trial (RCT), demonstrating the feasibility and acceptability of integrating twice-daily blood flow restriction (BFR)…
- Trial name
- NCT05719922
- Testing
- Resistance Training
- Where
- 6 sites in United Kingdom
- Volunteers
- 150 people
- Sponsor
- Defence Medical Rehabilitation Centre, UK
Anterior Cruciate Ligament Tear
Comparison of Early Versus Delay Reconstruction in Anterior Cruciate Ligament Tearing
The purpose of this study is to determine which surgical method is better for anterior cruciate ligament teas in outcomes.
- Trial name
- NCT01580722
- Testing
- early reconstruction, delay reconstruction
- Where
- Iran
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Anterior Cruciate Ligament Injury
Light Load Blood Flow Restriction Training in Anterior Cruciate Ligament Reconstruction Patient Rehabilitation
This study is examining the post-operative rehabilitation of anterior cruciate ligament (ACL) reconstruction patients within the National Health Service (NHS).
- Trial name
- NCT03419169
- Testing
- Light load BFR resistance training, Heavy load resistance training
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University College London Hospitals
Fracture, Fractures, Bone
FastFrame Knee Spanning and Damage Control Kit PMCF
The purpose of this prospective study is to confirm safety and performance of the FastFrame External Fixation System and corresponding instrumentation.
- Conditions
- Fracture, Fractures, Bone, Fractures, Closed, Fractures, Open
- Trial name
- NCT04730739
- Testing
- FastFrame External Fixation System - Knee Spanning or Damage Control Kit
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Zimmer Biomet
ACL Tear, ACL-injury
Do Patients With ACL Tears Demonstrate Weakness of the Soleus Muscle?
The goal of this prospective, cross-sectional study is to test the strength of the soleus muscle in participants who have a ACL tear confirmed by MRI.
- Conditions
- ACL Tear, ACL-injury, ACL - Anterior Cruciate Ligament Rupture
- Trial name
- ACL (NCT06235736)
- Where
- United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Tibial Plateau Fracture
Clinical Efficacy of Open Reduction and Suture Bridge Fixation for PCL Tibial Avulsion Fractures
Abstract Background: Posterior cruciate ligament (PCL) tibial avulsion fractures significantly impair knee function; however, optimal surgical fixation approaches are not agreed upon.
- Trial name
- fracture (NCT06918171)
- Testing
- Clinical Efficacy of Open Reduction and Anchor Suture Bridge Fixation
- Where
- China
- Volunteers
- 17 people
- Sponsor
- Second Affiliated Hospital of Soochow University
Knee Injuries and Disorders, Shoulder Disease
C Scope Visualization System Prospective Study
Evaluation of the performance and safety of the C Scope Visualization System
- Conditions
- Knee Injuries and Disorders, Shoulder Disease, Shoulder Injuries
- Trial name
- NCT05153863
- Testing
- C Scope Visualization System
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- CIT Ortho
ACL Injury
Real-time Sensorimotor Feedback for Injury Prevention in Males Assessed in Virtual Reality
Even though females are 2- to 10-times more likely to suffer an anterior cruciate ligament (ACL) injury, males represent the largest population of total ACL injuries.
- Trial name
- MaNMT (NCT04068701)
- Testing
- MaNMT Biofeedback
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Anterior Cruciate Ligament Injury
Blood Flow Restriction to Improve Muscle Strength After ACL Injury
Quadriceps muscle weakness is a common consequence following anterior cruciate ligament (ACL) injury and reconstruction. Maximizing quadriceps strength following ACL injury is significant as diminished quadriceps strength has…
- Trial name
- NCT03141801
- Testing
- DELFI PTS Personalized Tourniquet System for Blood Flow Restriction Training, Eccentric Exercise with BLAST Leg Press System, Concentric Exercise with BLAST Leg Press System
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Michigan
Knee Injury, Cartilage Injury
Norwegian Cartilage Project - Microfracture
114 patients between 18 and 50 years with an isolated focal cartilage defect in the knee will be randomized to either receive arthroscopic microfracture or arthroscopic debridement.
- Trial name
- NCT02637505
- Testing
- Arthroscopic microfracture (MF), Arthroscopic debridement (AD)
- Where
- Norway
- Volunteers
- 66 people
- Sponsor
- University Hospital, Akershus
Surgical Wound, Bilateral Total Knee Arthroplasty
Evaluating Edema and Range of Motion Using Negative Pressure Therapy vs. Standard Surgical Dressing in Bilateral TKA
This study will compare the effects of closed incision negative pressure dressing vs. standard of care silver dressing on lower limb swelling after bilateral primary total knee arthroplasty.
- Conditions
- Surgical Wound, Bilateral Total Knee Arthroplasty, Wounds and Injuries, Joint Diseases
- Trial name
- ENABLE (NCT04712019)
- Testing
- Closed Incision Negative Pressure Therapy (ciNPT), Standard Silver-containing Dressing
- Where
- 6 sites in United States
- Volunteers
- 10 people
- Sponsor
- Solventum US LLC
Female Athletes, Neuromuscular Training
Proprioception, Motor Control and Injury Risk on Female Wrestlers
This study aimed to examine the effect of a 4-week neuromuscular balance-based training program on landing mechanics as reflected by the Landing Error Scoring System-Real Time (LESS-RT), together with associated changes in knee…
- Conditions
- Female Athletes, Neuromuscular Training, Proprioception, Postural Balance
- Trial name
- NCT07504666
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Yalova
Tendinopathy
Comparative Research Among 3 Action Protocol in Other to Approach Chronic Patellar Tendinopathy
The accomplishment of a treatment with Intratissue Percutaneous Electrolysis of additional form to the accomplishment of eccentric exercise's program in patients with chronic patellar tendinopathy is more effective than the…
- Trial name
- NCT02498795
- Testing
- Group of Dry Needling, Group of Electrolysis, Control Group
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Universidad de Zaragoza
Blood Flow Restriction and Low-Intensity Resistance Training, Meniscal Injuries
Blood Flow Restriction Training After Meniscus Surgery
This study was conducted to investigate the effects of combined low-intensity resistance exercise with blood flow restriction (BFR-LIRE) on muscle strength, pain, and fear of movement in individuals who had undergone…
- Trial name
- NCT07299461
- Testing
- Traditional physical therapy exercises and physical therapy modalities, Traditional physical therapy exercises and physical therapy modalities + low-intensity resistance exercise with blood flow restriction (BFR-LIRE)
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Uskudar University
Osteoarthritis, Knee, Osteoarthritis, Hip
Wound Closure Materials and Techniques in Hip and Knee Arthroplasty
This prospective randomized clinical study aims to evaluate the effects of different suture materials and wound closure techniques on wound healing, functional outcomes, and postoperative complications in patients undergoing…
- Trial name
- NCT07439575
- Testing
- Barbed Suture Wound Closure, Conventional Suture Wound Closure
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bahattin Kemah
Lower Limb Amputation Above Knee (Injury)
The CYBERnetic Lower Limb Cocognitive Ortho-prosthesis Plus Plus, 1st Clinical Study (CLs++)
The aim of the study is to assess the efficacy and the usability of the cyberlegs ++ ortho prosthesis to improve the mobility and the quality of life in transfemoral amputees .
- Trial name
- NCT03376919
- Testing
- CLs++ gait training
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
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