Clinical trials: Wound; Knee
Cartilage Injury
Hyaluronic Acid Injection Post Arthroscopy - Does it Improve Immediate Function? Double Blind Controlled Prospective Study
The proposed research is to examine the effect of injecting a large volume of HA (10cc) at the time of post arthroscopy suture removal (9-11 day post surgery), in patients with cartilage damage of ICRS grade 2 and above in one of…
- Trial name
- NCT01442571
- Testing
- Hyaluronic Acid Injection, Saline Injection
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Hadassah Medical Organization
Wound Infection
Compare Antimicrobial to Conventional Suture in Patients Receiving Primary Total Knee Replacement
Total knee replacement is now one of the most popular reconstructive procedures for the elderly people to regain their functional capacity and life quality.
- Trial name
- Vicryl-Plus (NCT02533492)
- Testing
- vicryl, Vicryl plus
- Where
- Taiwan
- Volunteers
- 102 people
- Sponsor
- Mel Shiuann-Sheng Lee
Reliability in the Detection of ACL Injuries in Emergency Departments
Evaluation of the External Validity of the Knee SFA Score
A screening score for ACL (anterior cruciate ligament) injuries based on questioning has been developed by the Société Francophone d'Arthroscopie to provide better guidance for post-trauma patients.
- Trial name
- SCORESFA (NCT06960681)
- Testing
- External validity of the SFA score
- Where
- 3 sites in France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Rouen
Knee Ligament Injury
Performance and Safety of the Composite Interference Screw Used in Anterior Cruciate Ligament Reconstructions
The evaluation of the clinical data has demonstrated the conformity of the Composite Interference Screw (CIS), with the relevant essential requirements for its use in orthopaedic applications.
- Trial name
- NCT04076956
- Testing
- Anterior Cruciate Ligament Reconstruction
- Where
- France
- Volunteers
- 55 people
- Sponsor
- Biomatlante
Anterior Cruciate Ligament Injuries, Knee Osteoarthritis
Optimizing Movement After Anterior Cruciate Ligament Injury
Fifty percent of teenagers and young adults who suffer an anterior cruciate ligament (ACL) injury develop knee osteoarthritis (OA) within 15 years.
- Trial name
- NCT05363683
- Testing
- Squat Biofeedback, Standard Care
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Nebraska
Anterior Cruciate Ligament Tear
Prospective Femoral Versus Femoral and Sciatic Nerve Block for Anterior Cruciate Ligament (ACL) Reconstruction
The investigators propose that a preoperative femoral and sciatic blocks vs a femoral block only, prior to ambulatory anterior cruciate ligament (ACL) reconstruction will lead to a decrease in opiate consumption, pain scores, and…
- Trial name
- NCT01447277
- Testing
- Sciatic Block, Femoral Block only
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of California, San Francisco
ACL Injury, ACL Tears
Extended Oral Tranexamic Acid After Anterior Cruciate Ligament Reconstruction
This is a prospective, multi-center, randomized, double-blind, placebo-controlled trial evaluating the efficacy of oral tranexamic acid (TXA) in improving postoperative outcomes following anterior cruciate ligament reconstruction…
- Conditions
- ACL Injury, ACL Tears, ACL Surgery
- Trial name
- NCT07115056
- Testing
- Tranexamic Acid (TXA)
- Where
- 6 sites in United States
- Sponsor
- Campbell Clinic
Knee Osteoarthritis, Knee Injuries
Clinical Study of Novel Diagnostic Techniques for Knee Osteoarthritis
The purpose of this study is to clarify the potential of intra-articular ultrasound imaging, non-invasive ultrasound imaging, quantitative MRI imaging, contrast-enhanced CT imaging and arthroscopy for diagnostics of knee…
- Trial name
- NCT01359553
- Testing
- Intra-articular ultrasound imaging of knee joint during arthroscopy, Non-invasive ultrasound imaging of knee, Quantitative MRI imaging of knee
- Where
- Finland
- Volunteers
- 12 people
- Sponsor
- University of Oulu
Anterior Cruciate Ligament Injuries, Meniscus Tear
Magic Angle Direction Imaging (MADI) ACL Study
This study will be conducted to see if a new Magnetic Resonance Imaging (MRI) scanner could give additional information or help view the body in a different way.
- Trial name
- MADI (NCT07366619)
- Testing
- Magnetic Resonance Imaging
- Where
- 2 sites in United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Anterior Cruciate Ligament Injuries, Quadriceps Muscle Atrophy
The Effects of Whole-body Vibration on Increasing Quadriceps Strength in Patients With ACL Ruptures
Introduction: Approximately 35% patients can not return to sports after anterior cruciate ligament reconstruction(ACLR). Persistent quadriceps weakness is a factor that prevents patients return to sports.
- Trial name
- NCT04988828
- Testing
- Whole body vibration
- Where
- Hong Kong
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Anterior Cruciate Ligament Injuries
Hamstrings X Patellar Tendon for ACL Reconstruction in Soccer Players - RCT
The purpose of this study is to specifically evaluate outcomes of bone-patellar tendon-bone autograft versus hamstring autograft ACL reconstruction in soccer players.
- Trial name
- NCT02642692
- Testing
- Patellar Tendon graft, Hamstring Graft
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
ACL-injury
Influence of Injury to the Kaplan Fibers in Adult and Pediatric Patients With ACL Injury
The goal of this [type of study: observational study] is to [detect concomitant KF and ALL injury in knees with ACL injury using MRI in both adult and pediatric patients and compare the effect of KF injury and multiple risk…
- Trial name
- NCT06002308
- Testing
- Age
- Where
- China
- Volunteers
- 540 people
- Sponsor
- Sichuan Province Orthopetic Hospital
Drainage
Evaluating the Effectiveness of 2 Surgical Skin Preparation Methods in Reducing Surgical Wound Drainage After Total Hip or Knee Replacement
Surgical skin complications can be costly and could contribute to extended in-patient stay following total joint replacement or even the need for re-admission.
- Trial name
- NCT01097135
- Testing
- Duraprep Surgical Solution
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Rothman Institute Orthopaedics
Anterior Cruciate Ligament Rupture, Femoral Nerve Block
FNB in ACL Recon Under SA
The investigators will compare the results of sono-guided femoral nerve block in arthroscopic surgery for anterior cruciate ligament reconstruction under spinal anesthesia.
- Trial name
- NCT06048874
- Testing
- Sono-guided injection, Ropivacaine injection, Saline injection
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Chuncheon Sacred Heart Hospital
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
Functional and Self-reported Outcomes in Participants With a History of Musculoskeletal Knee Injury
Negative outcomes impact individuals with a history of ACL reconstruction (ACLR) despite completion of formal rehabilitation and clearance to return to physical activity (PA).
- Trial name
- NCT03617991
- Testing
- Exercise Group
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Johanna M. Hoch
Knee Injuries
AI Driven Biofeedback Wearable
The purpose of this study is to conduct a comprehensive clinical and biomechanical screening of high school, collegiate-level, recreational, and Olympic/professional-level athletes with the goal of identifying individual…
- Trial name
- NCT04921410
- Testing
- Biofeedback Knee Sleeve
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Peripheral Arterial Disease, Peripheral Vascular Disease
The Effect of Ischemic Conditioning on Strength and Ambulation in Subjects with PAD
Lower limb amputation is common in the United States, with approximately 150,000 amputations annually. Most individuals walking with a prosthesis demonstrate asymmetrical loading-i.e., they favor the amputated side by placing…
- Conditions
- Peripheral Arterial Disease, Peripheral Vascular Disease, Amputation, Lower Limb Amputation Knee
- Trial name
- NCT04937179
- Testing
- Ischemic Conditioning High - Active Comparator
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Illinois Chicago
Knee Injuries and Disorders
Evaluation of Long-term Isokinetic Training of Knee Joint
The goal of this clinical trial is to assess the effectiveness of isokinetic rehabilitation training under optimal stiffness in patients undergoing knee joint rehabilitation.
- Trial name
- NCT06674473
- Testing
- With robot assistance, traditional rehabilitation
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Peking University Third Hospital
Anterior Cruciate Ligament Injury
Synthetic Bone Graft Substitute vs. Autologous Spongiosa in Revision Anterior Cruciate Ligament Reconstruction
The overall objective is the histological and radiological assessment of bony consolidation of the tibial/femoral tunnel using either bone graft substitute (Actifuse) or autologous spongiosa in patients undergoing revision…
- Trial name
- NCT02845141
- Testing
- Actifuse, bone graft
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Berufsgenossenschaftliche Unfallklinik Ludwigshafen
Osteoarthritis, Knee
Postoperative Drainage in Total Knee Arthroplasty in the Presence of Tranexamic Acid
The investigator's aim with this study is to address, with the new paradigm of tranexamic acid, the role of wound drainage following total knee arthroplasty in blood loss, blood transfusion requirements and functional recovery
- Trial name
- NCT03915756
- Testing
- Drainage of surgical wound
- Where
- Portugal
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hospital Beatriz Ângelo