Clinical trials: Wound Dehiscence
Cesarean Wound Disruption
The Influence of Endometrial Suturing on the Risk of Uterine Scar Defect
Caesarean section (CS) is the commonest major operation performed on women worldwide with progressively rising incidence. Consequently, long-term adverse sequelae due to uterine scar defect have been increasing.
- Trial name
- NCT03851003
- Testing
- Endometrial suturing, Non- endometrial suturing, Vaginal ultrasonography
- Where
- Israel
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Cesarean Section Complications, Cesarean Wound Disruption
Cesarean Scar Defect Formation After First Cesarean Section.
This study is a prospective observational study which will monitor how cesarean section in the first pregnancy will develop a cesarean scar defect.
- Conditions
- Cesarean Section Complications, Cesarean Wound Disruption, Cesarean Wound; Dehiscence
- Trial name
- NCT03966001
- Testing
- Transvaginal sonography at six months after cesarean section, Transvaginal sonography at twelve months after cesarean section
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Uludag University
Obesity, Morbid, Obesity
CiNPT for Abdominoplasties in Post-bariatric Patients Study
The overarching goal of this research is to assess whether the post-operative use of closed-incision Negative Pressure Therapy (ciNPT) accelerates healing of surgical wounds, improves surgical outcomes, and reduces the rate of…
- Conditions
- Obesity, Morbid, Obesity, Obesity, Abdominal, Wound
- Trial name
- CAPS (NCT04214236)
- Testing
- ciNPT group, Control group
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera, Ospedale Civile di Legnano
Cesarean Wound; Dehiscence
Removal Versus Non Removal of Ceserean Section Scar .
EXCISION of cs section skin scar and subcutaneous release versus non removal in repeated cs .aRandomized controlled trial .
- Trial name
- cs (NCT05150678)
- Testing
- removal of ceserean section scar, non removal of cesearean section scar
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Assiut University
Suture, Complication, Wound
Split Scar Study to Assess Cosmetic Outcome From Differing Suture Spacing
The investigators wish to determine how suture spacing (5 mm vs. 10 mm) affects cosmetic outcome and development of "train tracking" in wounds.
- Conditions
- Suture, Complication, Wound, Wound Complication, Wound Dehiscence
- Trial name
- SFD (NCT03284983)
- Testing
- Suture spacing for wound closure
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Silver Falls Dermatology
Colon Cancer, Rectal Cancer
Pilot Study Evaluating the Efficacy of AlloMEM After Loop Ileostomy
The objective of this study is to investigate whether the use of Human Peritoneal Membrane (HPM) in a temporary loop ileostomy is beneficial to patients.
- Trial name
- AlloMem (NCT01113736)
- Testing
- AlloMEM™
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Cesarean Wound; Dehiscence, Cesarean Section Complications
Lower Uterine Segment Following a Cesarean Section With Barbed Suture
This aim of this study is to investigate the LUS in the pregnancy following a previous cesarean section with the use of barbed or conventional smooth suture.
- Trial name
- BARB-LOWSEGM (NCT05166174)
- Testing
- Transvaginal ultrasound in the third trimester pregnancy
- Where
- Italy
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Piazza della Vittoria 14 Studio Medico - Ginecologia e Ostetricia
Wound Dehiscence
Flipped Autograft for Treating Surgical Wound Dehiscence
This case report describes a novel technique for management of peri-implant wound dehiscence that involves using auto graft from the same surgical site to seal the dehiscence defect.
- Trial name
- NCT05513222
- Testing
- flipped autograft
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Wound Dehiscence
External Negative Pressure Dressing System vs. Traditional Wound Dressing for Cesarean Section Incision in Obese Women.
Obesity is associated with increased cesarean section delivery rates and surgical site infections with associated increased post-operative morbidity, post-operative pain and length of hospital stay.
- Trial name
- NCT04434820
- Testing
- External negative pressure dressing system (Yuwell 7E-A portable suction unit)
- Where
- Egypt
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Wound Heal, Wound Dehiscence
CiNPWT Lower Extremity Amputations (Closed Incision Neagtive Pressure Wound Therapy)
The objective of this study is to evaluate prospectively the effect of a novel application of Closed Incision Negative Pressure Wound Therapy(CiNPWT), as delivered by the V.A.C.
- Trial name
- CiNPWT (NCT06493539)
- Testing
- Standard of Care group, CINPWT
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Southern California
Surgical Site Infection
Skin Staples vs Polypropylene in Elective Laparotomy
Surgical site infection (SSI) is one of the most common postoperative complications following elective laparotomy and contributes significantly to patient morbidity, prolonged hospital stay, and increased healthcare costs.
- Trial name
- NCT07781878
- Testing
- Skin staples, Polypropylene skin suture
- Where
- Pakistan
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Wound Heal, Quality of Life
Clinical Wound Healing After Lower 3rd Molar Fully-impacted Surgery With 2 Types of Flap
The dehiscence distal to the second molar after lower third molar extraction is very common because the access flap for surgical extraction cannot be repositioned on a portion of healthy bone to guarantee suture support.
- Conditions
- Wound Heal, Quality of Life, Dehiscence
- Trial name
- NCT04314765
- Testing
- lower third molar extraction
- Where
- Italy
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Pregnancy Related, Cesarean Wound Disruption
The Collection and Application of Autologous Amniotic Fluid At Cesarean Delivery Closure.
The purpose of this study is to determine the feasibility of collecting amniotic fluid at delivery that will be immediately processed and then applied as a spray to the various layers of cesarean wound closure.
- Conditions
- Pregnancy Related, Cesarean Wound Disruption, Cesarean Section; Infection
- Trial name
- NCT04359472
- Testing
- Application of Autologous Amniotic Fluid
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Recibio, Inc.
Surgical Site Infection, Wound Complication
VAC Dressings for Colorectal Resections
Surgical Site Infections (SSIs) and wound complications are common occurrences following colorectal resection surgery. Incisional Negative Pressure Wound Therapy (iNPWT) has developing evidence for improving wound complication…
- Conditions
- Surgical Site Infection, Wound Complication, Wound Dehiscence, Seroma
- Trial name
- VACCRR (NCT02967627)
- Testing
- Incisional Negative Pressure Wound Therapy (iNPWT), Sterile Gauze Dressing
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Cesarean Scar Niche, Cesarean Wound; Dehiscence
Cesarean Scar Characteristics After Scheduled and Emergency Cesarean Deliveries
This study was designed to evaluate the scar characteristics following scheduled and emergency cesarean deliveries.
- Conditions
- Cesarean Scar Niche, Cesarean Wound; Dehiscence, Cesarean Section; Dehiscence
- Trial name
- NCT03609281
- Testing
- Ultrasound assessement of uterine scar
- Where
- Egypt
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Tanta University
Wound Heal, Cesarean Section Complications
The Effect of Suturing Material on Scar Healing
We want to compare the effects of 2 suture materials (monofilament and multifilament) on healing of the uterine scar after a cesarean delivery.
- Conditions
- Wound Heal, Cesarean Section Complications, Cesarean Wound Disruption, Suture Related Complication
- Trial name
- NCT03968783
- Testing
- Monofilament suture, Multifilament suture
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Cesarean Wound Disruption With Postnatal Complication
Comparative Analysis of Subcuticular Suture Materials in Cesarean Section
1.1. Background and Rationale Cesarean section is one of the most common surgical procedures performed worldwide. The choice of suture material for closing the skin incision is crucial, as it can influence wound healing, the risk…
- Trial name
- NCT06543329
- Testing
- polyglactin 910, poliglecaprone 25, polypropylene
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cesarean Section; Complications, Wound, Dehiscence
Effects of Abdominal Binders and TENS on Puerperium Period After Cesarean Section
To determine the combined effects of abdominal binders and TENS on post-operative pain, distress and constipation in puerperium period after cesarean section
- Trial name
- NCT06303245
- Testing
- ABDOMINAL BINDERS, TENS
- Where
- Pakistan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Dehiscence Wound, Secondary Perineal Tear
Conservative Treatment or Resuturing Among Women With Perineal Wound Dehiscence After Vaginal Labour
The goal of this observational study is to make us more aware of the short and long-term outcomes for women having an uncomplicated healing process after a rupture or birth cut in the perineum after giving birth in relation to a…
- Conditions
- Dehiscence Wound, Secondary Perineal Tear, Episiotomy; Dehiscence
- Trial name
- HEAL (NCT06026423)
- Testing
- Clinical examination and pictures, Questionnaire
- Where
- Denmark
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Cesarean Section Complications, Wound Breakdown
Antimicrobial Dressing Versus Standard Dressing in Obese Women Undergoing Cesarean Delivery
This will be an open label pilot randomized controlled clinical trial. Women undergoing cesarean delivery will be randomized to have standard wound dressing care or chlorohexidine gluconate (CHG) impregnated wound dressing…
- Conditions
- Cesarean Section Complications, Wound Breakdown, Wound Infection, Satisfaction
- Trial name
- NCT03887299
- Testing
- ReliaTect™ Post-Op Dressing (contains chlorohexidine gluconate or CHG), Standard Wound Care
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston