Clinical trials: Wound Healing Delayed
Diabetic Foot, Wound Healing Delayed
Ultrasonic Enhancement Delivery of Phosphodiesterase Inhibitors Nanoparticles for Diabetic Management of the Foot
The enhancement of cGMP levels at the wound site has shown beneficial effects in wound healing. Thus, topical or systemic application of phosphodiesterase 5 (PDE5) inhibitors, for example, sildenafil (Viagra), which is well-known…
- Conditions
- Diabetic Foot, Wound Healing Delayed, Diabete Mellitus, Amputation
- Trial name
- NCT07690566
- Testing
- Tadalafil
- Where
- Egypt
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Deraya University
Wound Healing
Clinical Effect of Endoscopic Surgery for Delayed Wound Healing After Achilles Tendon Suture
This study proposes endoscopic surgery for delayed wound healing after Achilles tendon suture which is a brand new treatment，and retrospectively analyzed the clinical data of 4 cases treated with this treatment.
- Trial name
- NCT04455490
- Testing
- Self-control
- Where
- China
- Volunteers
- 4 people
- Sponsor
- Peking University Third Hospital
Traumatic Anal Sphincteric Injury,Immediate vs Delayed Repair
Traumatic Anal Sphincteric Injury Immediate vs Delayed Repair
comparison between immediate and delayed repair regarding the need for another technique ,pain score or repositioning and need for repair.
- Trial name
- NCT05234931
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Appendicitis, Surgical Wound Infection
Primary Versus Delayed Wound Closure in Complicated Appendectomy (The HIEDI-Yemen Trial)
The goal of this clinical trial is to compare primary wound closure (PC) versus delayed primary closure (DPC) after standardized wound decontamination using the High-Efficiency Incision and Drainage with Irrigation (HIEDI)…
- Conditions
- Appendicitis, Surgical Wound Infection, Postoperative Complications, Wound Healing
- Trial name
- HIEDI-Yemen (NCT07688109)
- Testing
- Primary Closure with HIEDI, Delayed Primary Closure with HIEDI
- Where
- 3 sites in Yemen
- Volunteers
- 200 people
- Sponsor
- Sana'a University
Scars, Delayed Wound Healing
Nanofat on Wound Healing and Scar Formation
This study will evaluate the effectiveness and safety of intradermal injection of Nanofat on wound healing and scar formation.
- Conditions
- Scars, Delayed Wound Healing, Hypertrophic Scar, Post Inflammatory Hyperpigmentation
- Trial name
- NFWHSF (NCT03850119)
- Testing
- Nanofat injection
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Seroma as Procedural Complication, Hematoma Postoperative
Study to Evaluate the Performance of a Sustained Vacuum System
The purpose of this study is to evaluate the performance of the SOMAVAC® 100 Sustained Vacuum System after oncologic resections.
- Trial name
- NCT04554407
- Testing
- SOMAVAC® 100 Sustained Vacuum System
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- SOMAVAC Medical Solutions
Platelet-Rich Plasma, Wound Healing Delayed
Influence of Platelet Concentrates on Wound Healing
Chronic soft tissues defects can extend into the fat layer or even deeper and can cause functional disadvantages. Split-thickness skin grafts (STSGs) used to cover these wounds have varying success rates.
- Trial name
- NCT03667638
- Testing
- Platelet-Rich Plasma
- Where
- Germany
- Volunteers
- 5 people
- Sponsor
- Hannover Medical School
Delayed Healing
PICO Breast Reduction Clinical Study Looking at Incision Healing Complications
The purpose of this study is to see if the use of a single-use negative pressure wound therapy system (NPWT) will have an effect on the reduction of post-surgical incision healing complications following breast reduction surgery…
- Trial name
- NCT01640366
- Testing
- PICO
- Where
- 6 sites in United States, France and 2 more
- Volunteers
- 200 people
- Sponsor
- Smith & Nephew, Inc.
ACL Injury
Immediate Versus Optional Delayed Surgical Repair for Treatment of Acute ACL Injuries
Currently, most patients with an anterior cruciate ligament injury undergo surgery. There is a general belief that surgical reconstruction is necessary to safely return to sports and to prevent early knee osteoarthritis or…
- Trial name
- IODA (NCT05747079)
- Testing
- Rehabilitation, Optional delayed anterior cruciate ligament reconstruction, Immediate anterior cruciate ligament reconstruction
- Where
- Belgium
- Volunteers
- 280 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Rotator Cuff Tear
A Randomized Controlled Trial on the Effectiveness of Early Versus Conservative Rehabilitation Following Rotator Cuff Repair
Background Rotator cuff tears (RCTs) are a common, costly, and often persistent musculoskeletal complaint, with an increasing number of shoulder pain patients undergoing surgical repair each year.
- Trial name
- NCT07324174
- Testing
- Group A, Therapeutic exercises, education and advice, Group B (Control Group)
- Where
- Saudi Arabia
- Volunteers
- 86 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Kidney Transplantation
Everolimus in de Novo Kidney Transplant Recipients
The purpose of this study was to evaluate whether delayed (i.e. 28 ± 4 days post-transplant) administration of everolimus after transplantation reduces the risk of wound healing complications in comparison with immediate…
- Trial name
- NEVERWOUND (NCT01410448)
- Testing
- Everolimus, Mycophenolate sodium, Cyclosporine
- Where
- 22 sites in Italy
- Volunteers
- 383 people
- Sponsor
- Novartis Pharmaceuticals
Gynecomastia, Delayed Wound Healing
Nitropaste in Breast Reduction
The purpose of this study is evaluate the effect of Nitroglycerin paste on wound healing and scarring. Previous research has shown that Nitroglycerin paste can improve the blood flow to a wound, which may be associated with…
- Trial name
- NCT04321967
- Testing
- Nitroglycerin Paste, Dermabond
- Where
- United States
- Sponsor
- Icahn School of Medicine at Mount Sinai
Elective Foot and Ankle Surgery.
Use of Platelet-Rich Plasma (PRP) and Platelet-Poor Plasma (PPP) to Prevent Infection and Delayed Wound Healing
The purpose of this study is to see if applying PRP and PPP to surgical sites and the closing incision helps prevent infection and slow wound healing.
- Trial name
- PRP (NCT01639144)
- Testing
- PRP and PPP
- Where
- United States
- Volunteers
- 515 people
- Sponsor
- Gary M. Kiebzak, Ph.D.
Diabetes Mellitus, Type 2, Delayed Wound Healing
Hyaluronic Acid Treatment of the Post-extraction Tooth Socket Healing in Subjects With Diabetes Mellitus Type 2
The aim of the present split-mouth study was to investigate the effect of Hyaluronic Acid (HA) in improving the post-extraction tooth socket healing in subjects with diabetes mellitus type 2.
- Conditions
- Diabetes Mellitus, Type 2, Delayed Wound Healing, Tooth Extraction Status Nos
- Trial name
- NCT05896319
- Testing
- Hyaluronic acid gel
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- University of Turin, Italy
Multiple Sclerosis (MS), Multiple Sclerosis, Relapsing-Remitting
Assessing Changes in Multi-parametric MRI in MS Patients Taking Clemastine Fumarate as a Myelin Repair Therapy
The clinical trial is intended to assess for clinical evidence of Clemastine Fumarate as a myelin repair therapy in patients with chronic inflammatory injury-causing demyelination as measured by multi-parametric MRI assessments.
- Conditions
- Multiple Sclerosis (MS), Multiple Sclerosis, Relapsing-Remitting, Multiple Sclerosis, Primary Progressive, Multiple Sclerosis, Chronic Progressive
- Trial name
- ReVIVE (NCT05359653)
- Testing
- Clemastine Fumarate
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of California, San Francisco
Rotator Cuff Tear Repair
Early Versus Delayed Postoperative Mobilization After Arthroscopic Rotator Cuff Tear Reapair.
Arthroscopic suture for complete and partial >50% thickness Rotator Cuff Tears (RCT) is the gold standard. However, there is no evidence of superiority of delayed postoperative mobilization protocols versus early ones, in terms…
- Trial name
- RAPIDREHAB (NCT04458025)
- Testing
- Standard rehabilitation program, Early rehabilitation program
- Sponsor
- Borja Alcobía-Díaz MD, PhD
Erectile Dysfunction
Penile Fracture: A Comparison of Erectile Function After Immediate Repair Versus Delayed Repair
To prospectively compare erectile function at 12 months, utilizing the abbreviated International Index of Erectile Function-5 (IIEF-5) score, for men treated with an immediate repair versus a delayed repair.
- Trial name
- NCT03449940
- Testing
- Immediate repair, Delayed repair, Lidocaine
- Where
- 2 sites in Jamaica
- Volunteers
- 46 people
- Sponsor
- Ministry of Health, Jamaica
ExtraCorporeal Life Support (ECLS), Wound Infection
Investigating the Impact of Cold Atmospheric Plasma Treatment on Wound Healing at Cannulation Sites in Patients Following Extracorporeal Life Support
This study aims to evaluate a new wound treatment called cold atmospheric plasma (CAP) for patients receiving extracorporeal life support (ECLS).
- Conditions
- ExtraCorporeal Life Support (ECLS), Wound Infection, Surgical Site Infection, Delayed Wound Healing
- Trial name
- NCT07501897
- Testing
- Cold Atmospheric Plasma (CAP) Therapy, Standard wound care
- Where
- Taiwan
- Volunteers
- 65 people
- Sponsor
- National Taiwan University Hospital
Non-union or Delayed Healing Fractures
Evaluation of the Risk for Radiographic and Clinical Nonunion in Patients With Previous Bisphosphonates Therapy.
Dose and duration of bisphosphonate therapy will increase the likelihood that patients experience delayed healing of non-union fractures.
- Trial name
- NCT01731535
- Where
- United States
- Sponsor
- University of Wisconsin, Madison
Limb Edema, Surgical Site Infections
Prevention of Edema After Coronary Artery Bypass Graft by Customized Pressure-guided Elastic Bandages
The study aimed to assess the efficacy of customized pressure-guided elastic bandages (CPG-EB) in preventing postoperative edema and complications in Coronary Artery Bypass Graft (CABG) patients.
- Conditions
- Limb Edema, Surgical Site Infections, Leg Swelling, Compression Bandages
- Trial name
- PEACCE (NCT06603961)
- Testing
- CPG-EB group
- Where
- 2 sites in Thailand
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital