Clinical trials: Wound Management
Hidradenitis Suppurativa (HS)
Hidradenitis Suppurativa Wound Care
The objective of this case series is to monitor time and outcome of healing of wounds associated with HS using Endoform [ovine forestomach], Hydrofera Blue [methylene blue and gentian violet], and Hypafix tape.
- Trial name
- NCT04354012
- Testing
- methylene blue, gentian violet, and ovine forestomach wound dressings
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Wake Forest University Health Sciences
Diabetic Foot Ulcers
A Trial Examining Cellular Energetics Related to Various Wound Treatment Therapies
A randomized, controlled pilot study examining how cellular energetics related to various wound treatment therapies in patients with diabetic foot ulcers.
- Trial name
- NCT00605189
- Testing
- Powered Suction Pump (VAC Freedom), Powered Suction Pump, MWT
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- KCI USA, Inc
Traumatic Amputation
Strength, Pain and Function in Operation Iraqi Freedom/Operation Enduring Freedom Amputees: A Nurse-Managed Program
The purpose of this randomized control study is to determine if administering neuromuscular electrical stimulation (NMES) to the thigh muscles of a below the knee amputee is more effective than the current standard of care in…
- Trial name
- NCT00942890
- Testing
- NMES (EMPI 300PV stimulator) plus standard of care, TMARP standard of care
- Where
- 3 sites in United States
- Volunteers
- 44 people
- Sponsor
- University of Tennessee
Burns
Evaluation of Oxygen Diffusion Dressing for Accelerating Healing of Donor Site and Other Wounds
This is a single-center, prospective, randomized, and controlled study to evaluate the effectiveness of OxyBand Dressing for the use as a dressing for autogenous skin donor sites compared to our current standard donor site…
- Trial name
- NCT01268189
- Testing
- Oxygen diffusing dressing, Standard of care dressing
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- United States Army Institute of Surgical Research
Chronic Wound, Venous Leg Ulcer
Clinical Study to Compare 3 Multi-Layered Foam Dressings for the Management of Chronic Wounds
A prospective, randomized, controlled clinical trial (RCT) using a cross-over (repeated measures) design to evaluate safety and efficacy of three foam wound dressings in the local management of chronic wounds.
- Conditions
- Chronic Wound, Venous Leg Ulcer, Diabetic Foot Ulcer
- Trial name
- NCT03662997
- Testing
- Bordered Five-Layer Foam Dressing, Hydropolymer Foam Dressing, Hydrocellular Multi-Layer Foam Dressing
- Where
- 5 sites in United States
- Volunteers
- 40 people
- Sponsor
- Molnlycke Health Care AB
Diabetic Foot Ulcers
A Pilot Study of the Provant Therapy System in Subjects With Diabetic Foot Ulcers
The objective of this study is to compare the reduction in wound surface areas between patients with diabetic ulcers utilizing Provant's pulsed radio frequency energy therapy (PRFE) as an adjunct to standardized basic wound care…
- Trial name
- NCT00761176
- Testing
- The Provant Therapy System
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Regenesis Biomedical, Inc.
Spinal Cord Injury
Subarachnoid Administrations of Adults Autologous Mesenchymal Stromal Cells in SCI
The study goes on 24 months, with recruiting, treatment and follow period for all patients. The first day for each patient will be the first cellular administration. 3 doses will be administrated every 3 months from first dose.
- Trial name
- NCT02165904
- Testing
- Adult Autologous Mesenchymal Bone Marrow Cell
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Puerta de Hierro University Hospital
Primary Graft Dysfunction
Sodium Nitrite in Lung Transplant Patients to Minimize the Risk of Pulmonary Graft Dysfunction
This is a Phase 2 observational nonrandomized pilot investigation to evaluate the safety and efficacy of Sodium Nitrite administration for the reduction of Primary Graft Dysfunction (PGD) in patients undergoing lung transplant.
- Trial name
- NCT01715883
- Testing
- Sodium Nitrite
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Gladwin, Mark, MD
Surgical Wound
The Closer Trial: A Safety and Efficacy Study of the Rex Medical Vascular Sealing System
The objective of this trial is to demonstrate the safety and effectiveness of the Rex Medical Closer Vascular Sealing System in sealing femoral arterial access sites.
- Trial name
- Closer (NCT02136004)
- Testing
- Closer VSS
- Where
- 12 sites in United States
- Volunteers
- 220 people
- Sponsor
- Rex Medical
Chronic Pain, Traumatic Brain Injury
Neuromodulatory Treatments for Pain Management in TBI
Traumatic brain injury (TBI) and chronic pain are common and serious health problems for military veterans and often co-occur, leading to poor post-deployment adjustment.
- Conditions
- Chronic Pain, Traumatic Brain Injury, Posttraumatic Stress Disorder
- Trial name
- NCT03418129
- Testing
- Mindfulness, Neurofeedback, Relaxation
- Where
- United States
- Volunteers
- 254 people
- Sponsor
- Duke University
Chronic Kidney Disease
RenalGuard System and Contrast Media
The purpose of the present study is to assess the role of the RenalGuard System as compared to the optimal strategy (sodium bicarbonate infusion plus N-acetylcysteine (NAC)) in high and very-high risk patients to prevent…
- Trial name
- REMEDIALII (NCT01098032)
- Testing
- RenalGuard system, Systemic alone therapy
- Where
- 4 sites in Italy
- Volunteers
- 294 people
- Sponsor
- Clinica Mediterranea
Stress Disorders, Post-Traumatic
Post Traumatic Stress Disorder (PTSD) Hyperarousal Symptoms Treated With Physiological Stress Management
Hyperarousal is a key symptom of PTSD. Even after receiving trauma-focused therapy, PTSD patients may continue to suffer from hyperarousal.
- Trial name
- BaRT (NCT00855816)
- Testing
- Breathing training
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Healthy Athlete
Movement Assessment for Concussion Management
Previous work in the area of concussion management has focused heavily on neuro-cognitive testing. In addition to routine neuro-cognitive testing through Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT),this…
- Trial name
- NCT02776904
- Testing
- Immediate Post-concussion Assessment and Cognitive Testing, Gait with single and dual task, Y-Balance test
- Where
- United States
- Volunteers
- 327 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Hip Fractures, Analgesia
Comparison of the Efficiency of Femur Nerve Block and Intravenous Analgesia Treatment in Hip Fracture Patients
It is well-established that hip fractures impose a significant medical, socioeconomic, and financial burden. In the elderly population, the associated mortality and morbidity are particularly pronounced: within one year following…
- Conditions
- Hip Fractures, Analgesia, Femoral Nerve
- Trial name
- NCT06862154
- Testing
- IV Analgesia- Fentanyl, Femoral Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Marmara University
PTSD, Overweight
MOVE!+UP: Testing a Tailored Weight Management Program for Veterans With PTSD
Posttraumatic Stress Disorder (PTSD) is common among Veterans and results in poor psychological functioning, quality of life, and physical health.
- Conditions
- PTSD, Overweight, Obesity
- Trial name
- NCT04563741
- Testing
- MOVE!+UP, MOVE!
- Where
- United States
- Volunteers
- 174 people
- Sponsor
- VA Office of Research and Development
Apnea of Prematurity, Intraventricular Hemorrhage
MRI and Neurodevelopment in Preterm Infants Following Administration of High-Dose Caffeine
Over the last 30 years the survival rates for babies born prematurely have improved greatly with research. As these babies grow up, we have found that many of the premature babies have learning and movement problems.
- Conditions
- Apnea of Prematurity, Intraventricular Hemorrhage, Brain Injury
- Trial name
- NCT00809055
- Testing
- Caffeine citrate
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Washington University School of Medicine
Low Level Laser Therapy, Healthy
Effect of GaAlAs 940 Laser on Pain and Wound Healing After Free Gingival Graft
This randomized controlled clinical trial aims to evaluate the biomodulatory effects of a 940-nm GaAlAs diode laser on postoperative pain control and wound healing at the palatal donor site following free gingival graft…
- Conditions
- Low Level Laser Therapy, Healthy, Postoperative Pain Management, Wound Healing
- Trial name
- NCT07308912
- Testing
- 940 nm GaAlAs diode laser, palatal stent
- Where
- Vietnam
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Prosthesis-related Infections, Wound Complications
Evaluation of Wound Management With Negative Pressure Dressing Versus Standard Dressing After Revision Arthroplasty.
The purpose of this study is to determine the efficacy of a negative pressure wound therapy (NPWT) system after revision total knee and hip arthroplasty in patients at high risk for infection.
- Conditions
- Prosthesis-related Infections, Wound Complications, Joint Diseases, Musculoskeletal Diseases
- Trial name
- NCT02127281
- Testing
- Prevena
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- The Cleveland Clinic
Ischemic Heart Disease, Bone Marrow Cells
Autologous Bone Marrow Mononuclear Cells in the Combined Treatment of Coronary Heart Disease
The purpose of this study evaluate the effect of the method of administration of autologous bone marrow mononuclear cells for the duration of of functioning aorto-coronary bypass grafts in the surgical treatment of coronary heart…
- Conditions
- Ischemic Heart Disease, Bone Marrow Cells, Coronary Artery Bypass Grafting (CABG), Heart Failure, Diastolic
- Trial name
- TAMIS (NCT02059512)
- Testing
- Group 1, Group 0, Group 2
- Where
- Russia
- Volunteers
- 117 people
- Sponsor
- St. Petersburg State Pavlov Medical University
Acute Pain, Wound Care
RCT: Fentanyl Plus Ketamine Versus Fentanyl Alone for Acute Burn Pain
The Ketamine for Acute Pain in Burns study is a randomized, double-blind, parallel group trial (RCT) with active control (usual care) contrasting the efficacy and safety of "Ketamine Plus Opiate-based usual care" (O+K) with the…
- Conditions
- Acute Pain, Wound Care, Posttraumatic Stress Disorder
- Trial name
- NCT03305055
- Testing
- ketamine, Fentanyl
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Johns Hopkins University