Clinical trials: Wounds, Gunshot
Full-thickness Skin Defects, Degloving Injuries
RECELL® System Combined With Meshed Autograft for Reduction of Donor Skin Harvesting in Soft Tissue Reconstruction
A prospective randomized within-subject controlled study to compare the clinical performance of conventional autografting with and without the RECELL system on acute non-burn full-thickness skin defects.
- Conditions
- Full-thickness Skin Defects, Degloving Injuries, Crush Injuries, Laceration of Skin
- Trial name
- NCT04091672
- Testing
- Control Intervention (Conventional Autograft), Investigational Intervention (RECELL + more widely meshed autograft)
- Where
- 18 sites in United States
- Volunteers
- 65 people
- Sponsor
- Avita Medical
Wounds, Gunshot
Helping Individuals With Firearm Injuries
The investigators will conduct a cluster randomized trial of an intervention program that combines a hospital-based intervention, structured outreach program, and multi-agency attention.
- Trial name
- HIFI (NCT02630225)
- Testing
- Critical Time Intervention, Treatment as Usual, Motivational Interviewing
- Where
- United States
- Volunteers
- 232 people
- Sponsor
- University of Washington
Chronic Pain, Psychological Disorders
Influence of Psychological Status on the Results of Pain Treatment in Patients With Gunshot and Mine-explosive Wounds
82.1% of patients with gunshot and mine-explosive wounds and wounds during hostilities in Ukraine have negative results of pain treatment, which leads to its chronicity.
- Trial name
- IPSRPTPGaM-EW (NCT05478642)
- Testing
- The Hospital Anxiety and Depression Scale.
- Where
- Ukraine
- Volunteers
- 2,215 people
- Sponsor
- Bogomolets National Medical University
Chronic Pain
The Influence of the Results of Surgical Treatment in Patients With Gunshot and Mine-explosive Wounds on the Formation of Chronic Pain
In 82.1% of patients with gunshot and mine-explosive injuries, the pain becomes chronic. The impact of the results of surgical treatment on the processes of chronic pain in this category of patients remains insufficiently…
- Trial name
- FRSTPGaM-EW (NCT05485311)
- Testing
- visual analog scale
- Where
- Ukraine
- Volunteers
- 2,215 people
- Sponsor
- Bogomolets National Medical University
Wounds, Gunshot, Arm Injuries
Trial of Negative-pressure Wound Therapy Use in Conflict-related Extremity Wounds
There is a treatment method called negative-pressure wound therapy (NPWT) that is well established and used for the treatment of wounds.
- Conditions
- Wounds, Gunshot, Arm Injuries, Leg Injuries, Wound Infection
- Trial name
- VACoCREW (NCT02444598)
- Testing
- Vaccum Assisted Closure device, Conventional wound dressings
- Where
- 2 sites in Iraq, Jordan
- Volunteers
- 116 people
- Sponsor
- Karolinska Institutet
Wounds and Injuries, War-Related Injuries
Wound Bacterial Microbiota and Their Antibiotic Resistance
The purpose of the study is to explore the microbiology in war-associated wounds of hospitalized patients from the Syrian armed conflict. Cultures collected from acute wounds with clinical signs of infection will be analyzed.
- Conditions
- Wounds and Injuries, War-Related Injuries, Wound Infection, Wounds, Penetrating
- Trial name
- NCT02744144
- Where
- Jordan
- Volunteers
- 457 people
- Sponsor
- Karolinska Institutet
Gun Shot Wound
Effect of Violent First-Person Shooter (FPS) Video Games on Shooting Accuracy
The present research tests the effects of violent shooting games on behavior within the game (Pilot Study) and on behavior after the game is turned off (Experiment Proper).
- Trial name
- NCT03445156
- Testing
- Video game, Controller
- Volunteers
- 327 people
- Sponsor
- Ohio State University
Chronic Pain
The Influence of the Volume of Injuries and Surgical Operations on the Results of Pain Treatment in Patients With Gunshot and Mine-explosive Wounds at the Stages of Treatment
Treatment of pain in patients with gunshot and mine-explosive injuries in the stages of treatment is important, because in 82.1% the pain becomes chronic. This indicates that treatment results need to be improved.
- Trial name
- IVaSORPTP (NCT05485298)
- Testing
- visual analog scale
- Where
- Ukraine
- Volunteers
- 2,215 people
- Sponsor
- Bogomolets National Medical University
Wounds and Injuries, War-Related Injuries
Retrospective Morbidity and Mortality Study of Conflict-Related Injuries: Erbil, Iraq
A retrospective morbidity and mortality study, using routinely collected data, investigating the epidemiology of patients with conflict-related injuries presenting to a dedicated trauma hospital in Erbil, Iraq, during the…
- Conditions
- Wounds and Injuries, War-Related Injuries, Gunshot Wound, Blast Injuries
- Trial name
- NCT03358758
- Where
- Sweden
- Volunteers
- 1,832 people
- Sponsor
- Karolinska Institutet
Abdominal Injuries
Feasibility and Usability of Intraoperative Fluorescent Angiography With Indocyanine Green in Penetrating Abdominal Trauma
The surgical management of penetrating bowel and intestinal injuries, inflicted via a gunshot or knife stabbing, has long been a topic of debate [1-3].
- Trial name
- NCT04534816
- Testing
- Indocyanine Green
- Where
- South Africa
- Volunteers
- 20 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Chronic Pain
The Concept of Pain Treatment in Patients With Gunshot and Mine-explosive Wounds and to Develop an Algorithm for Analgesia at the Stages of Treatment
in 82.1% of cases it is not possible to achieve a positive result of pain treatment
- Trial name
- CPTGaM-EW (NCT05485324)
- Testing
- visual analog scale
- Where
- Ukraine
- Volunteers
- 2,215 people
- Sponsor
- Bogomolets National Medical University
Chronic Pain
Predictors of Treatment Failure Pain Among Patients Gunshot Wounds
In patients with gunshot wounds during hostilities in Ukraine, 76.9% have negative results of pain treatment, which leads to its chronicity.
- Trial name
- PTFPAPGW (NCT05482061)
- Testing
- visual analog scale (VAS).
- Where
- Ukraine
- Volunteers
- 2,215 people
- Sponsor
- Bogomolets National Medical University
Gun Shot Wound
Mississippi Violence Injury Prevention (VIP) Program
This clinical trial is designed to evaluate the effectiveness of three interventions aimed at preventing violence and supporting those affected by it.
- Trial name
- MS-VIP (NCT06736730)
- Testing
- Hospital-Linked Violence Intervention Program, Mobile Community Event Support, Unrestricted Cash Assistance
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of Mississippi Medical Center
Gunshot Wound, Obesity & Overweight
Obesity and Outcomes After Surgery for Thoracoabdominal and Abdominal Gunshot Injuries
This retrospective observational study evaluated whether obesity was associated with outcomes after surgery for thoracoabdominal or isolated abdominal gunshot injuries.
- Conditions
- Gunshot Wound, Obesity & Overweight, Abdominal Injuries
- Trial name
- NCT07788963
- Testing
- Obesity Status
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Trauma, Multiple, Gun Shot Wound
A Snapshot Study of Patients Affected by Gunshot Related Injuries in Trauma in South Africa
Introduction- Gun violence represents an important cause of disability to the working age population in South Africa. It has unrecognised, but undoubtedly significant implications for the health service and patients affected by…
- Trial name
- GRIT (NCT03854591)
- Testing
- No intervention
- Where
- South Africa
- Volunteers
- 138 people
- Sponsor
- University of Cape Town
Gunshot Entry Wound
Predictors of Treatment Failure Among Patients With Gunshot Wounds and Post-traumatic Stress Disorder
The 82.1% treatment failure of post-traumatic stress disorder(PTSD), associated with gunshot wounds, is related to high incidence of chronic pain syndrome as well as resistance to the PTSD treatment.
- Trial name
- NCT04689022
- Testing
- Mississippi Scale for Combat-Related PTSD (M-PTSD), visual analogue scale (VAS), Douleur Neuropathique 4 questions (DN4)
- Volunteers
- 218 people
- Sponsor
- Vasyl' Horoshko
Gunshot Wound
Epidemiology of Gunshot Wounds Injuries Admitted in ICU in France
In civilian practice, the incidence of firearm violence depends on the country. In high income countries, most cases are reported in the USA or South Africa.
- Trial name
- GSW_in_ICU (NCT05224570)
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Wounds and Injuries
A Single Site Safety and Tolerability Study of HBOC-201 in Trauma Subjects
The main purpose of this study is to determine if HBOC-201 is safe and tolerable to trauma subjects, when given to treat the inadequate supply of blood and nutrients to tissues and organs.
- Trial name
- NCT00301483
- Testing
- Hemoglobin-based oxygen carrier-201 (HBOC 201), Standard of Care
- Where
- South Africa
- Volunteers
- 53 people
- Sponsor
- Biopure Corporation
Chronic Pain, Widespread
Predictors of Pain Chronicity in Patients With Gunshot and Mine-explosive Wounds
82.1% of patients with gunshot and mine-explosive wounds during hostilities in Ukraine have negative results of pain treatment, which leads to its chronicity.
- Trial name
- PPСPGM-EW (NCT05478668)
- Testing
- visual analog scale
- Where
- Ukraine
- Volunteers
- 2,215 people
- Sponsor
- Bogomolets National Medical University
PTSD, Stress, Psychological
Relief of Symptoms of Post-traumatic Stress for Victims of Gun Violence
To test the hypothesis that adult individuals who are victims of gun violence will have decreased symptoms of post-traumatic stress after an individual-level intervention with the Screening and Tool for Awareness and Relief of…
- Conditions
- PTSD, Stress, Psychological, Gunshot Wound
- Trial name
- NCT03916614
- Testing
- Screening Tool for Relief of Trauma (START), standard of care
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Yale University