Clinical trials: Wounds and Injuries, Ankles
Chronic Ankle Instability, Ankle Sprain
Impact of Chronic Ankle Instability on Jumping and Agility in Athletes
This study investigated how chronic ankle instability (CAI) affects functional performance in athletes compared with healthy controls.
- Conditions
- Chronic Ankle Instability, Ankle Sprain, Functional Performance Deficit, Athletic Performance
- Trial name
- NCT07171398
- Testing
- Functional Performance Testing Battery
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Arthritis, Rheumatoid Arthritis
Wright Foot & Ankle Post-Market Observational Study
WRIGHT FOOT \& ANKLE POST-MARKET OBSERVATIONAL STUDY, Multi-Year, Multi-Site, Multi-Device, Post-Market Observational Study, 10 sites, a minimum of 40 patients per device
- Conditions
- Arthritis, Rheumatoid Arthritis, Fracture, Trauma Injury
- Trial name
- NCT04118894
- Testing
- Foot and Ankle Devices
- Where
- 5 sites in United States, France and 2 more
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Stryker Trauma and Extremities
Ankle Injuries
Ankle Instability Treatment in Patients With Chronic Ankle Instability
Ankle joint self mobilization.
- Trial name
- NCT03189784
- Testing
- mobilization with movement techniques
- Where
- 2 sites in Spain
- Volunteers
- 52 people
- Sponsor
- University of Jaén
Ankle Injuries
Lateral Ankle Sprain and Platelet Rich Plasma
Lateral ankle sprains are one of the most common in sports medicine. Considering the sprains in general, they represent an 85% of the ankle lesions. The incidence in high performance athletes range from 16 to 21%.
- Trial name
- NCT02609308
- Testing
- Short leg cast, Platelet-rich plasma
- Where
- Mexico
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Nuevo Leon
Acute Pain
A Double-blind, Double-dummy, Multicenter, Randomized Study of the Efficacy and Tolerability of Valdecoxib 40 mg Versus Rofecoxib 50 mg in Treating the Symptoms of Ankle Sprain
The study compares valdecoxib 40 mg once daily vs. rofecoxib 50 mg one daily in treating the signs and symptoms of acute first- or second-degree ankle sprain.
- Trial name
- NCT00657449
- Testing
- valdecoxib, rofecoxib
- Where
- 8 sites in Brazil
- Volunteers
- 45 people
- Sponsor
- Pfizer
Post-Traumatic Osteoarthritis of Ankle, Ankle Osteoarthritis
Indications for Osteochondral Allograft Transplantation
With IRB approval, a prospective single-cohort clinical trial will be performed to assess safety and efficacy of total biologic arthroplasty of the ankle.
- Conditions
- Post-Traumatic Osteoarthritis of Ankle, Ankle Osteoarthritis, Ankle Injuries
- Trial name
- NCT03711747
- Testing
- Osteochondral allograft ankle
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Missouri-Columbia
Ankle Fractures, Trauma Injury
Effect of Toradol on Post-operative Foot and Ankle Healing
The use of Toradol for pain control in surgical orthopedic cases is currently a topic of interest within the field. The proposed study is a prospective randomized study evaluating postoperative pain, opioid requirement…
- Trial name
- NCT03727048
- Testing
- Ketorolac, No ketorolac
- Volunteers
- 128 people
- Sponsor
- Rothman Institute Orthopaedics
Musculoskeletal Pain, Low Back Pain
Group-based Exercise Training Programs for Military Members With Musculoskeletal Conditions
This randomized controlled trial will compare the mid- and long-term effects of group-based training programs with usual individual physiotherapy care for the treatment of musculoskeletal disorders in military.
- Conditions
- Musculoskeletal Pain, Low Back Pain, Rotator Cuff Tendinitis, Patellofemoral Pain Syndrome
- Trial name
- NCT05235152
- Testing
- Usual individual physiotherapy care, Group-supervised physiotherapy training programs
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Laval University
Ankle Fractures, Ligament Rupture
A New Method for Deltoid Ruptures: Gap Sign
"Deltoid Gap Sign" which would be a new method of examination for deltoid ligament injuries will be investigated. It will be analyzed if it is correlated with the external rotation stress test.
- Conditions
- Ankle Fractures, Ligament Rupture, Ligament Injury
- Trial name
- NCT05188391
- Testing
- Deltoid Gap Sign
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Goztepe Training and Research Hospital
Ankle Fractures
Postoperative Computed Tomography Detection of Syndesmotic Malreduction in Ankle Fractures
This prospective observational cohort study aims to evaluate the ability of postoperative plain radiographs to detect syndesmotic reduction accuracy in patients with ankle fractures requiring syndesmotic fixation.
- Trial name
- NCT07338149
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Cairo University
Ankle Sprains, Ankle Injuries
The Effect of Different Talocrural Joint Mobilization Techniques in Lateral Ankle Sprain
Decreased ankle dorsiflexion range of motion (DFROM) has been identified among the factors that increase the risk of lateral ankle sprain (LAS) in basketball players.
- Conditions
- Ankle Sprains, Ankle Injuries, Kinesiophobia, Jumping From Height
- Trial name
- NCT06295198
- Testing
- Single lep drop jump test
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Bahçeşehir University
Ankle Fractures, Pilon Fracture
FRAME Study (Frailty-Related Ankle Fracture Management and Evaluation)
This will be a multi-centre randomized controlled trial, with London Health Sciences Centre (LHSC) as the lead site. Elderly patients with complex ankle fractures who meet the inclusion criteria and provide consent will be…
- Trial name
- FRAME (NCT05131321)
- Testing
- Primary ankle arthrodesis (fusion), ORIF (open reduction and internal fixation), Intramedullary Fibular Nailing (IMFN)
- Where
- Canada
- Volunteers
- 172 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Lateral Malleolus Fracture
A Study to Compare Two Different Managements After Ankle Surgery: Immediate and Delayed Weight-bearing.
The investigators will compare two types of rehabilitation in patients who undergo a surgery for treatment of malleolar fractures: immediate complete weight-bearing and delayed weight-bearing.
- Trial name
- NCT04429217
- Testing
- immediate post-operative complete weight-bearing after surgery, delayed weight-bearing for 6 weeks after surgery
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Open Tibia Fracture, Open Dislocation of Ankle
Accelerated Flap Coverage Versus Standard Timing in the Treatment of Severe Lower Extremity Musculoskeletal Injuries
The goal of this randomized controlled trial is to determine if accelerated flap coverage compared to standard flap coverage timing leads to improved infection-related complications in patients with open fractures and/or…
- Conditions
- Open Tibia Fracture, Open Dislocation of Ankle, Extremity Fracture Lower, Extremity Injuries Lower
- Trial name
- FLAP ATTACK (NCT07828613)
- Testing
- Accelerated Flap Coverage Surgery, Standard of Care Flap Timing
- Where
- 31 sites in United States
- Volunteers
- 356 people
- Sponsor
- Johns Hopkins University
Shoulder Injuries, Hip Injuries
JuggerKnot With Broadband PMCF Study
The purpose of the study is to collect post-market clinical follow-up data, which is needed to confirm the safety and performance of the JuggerKnot device and meet existing EU regulatory requirements.
- Conditions
- Shoulder Injuries, Hip Injuries, Foot Injury, Ankle Injuries
- Trial name
- NCT05762588
- Testing
- Juggerknot with Broadband tape
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Riverpoint Medical
Ankle Sprain
HKT-500 in the Treatment of Adult Patients With Ankle Sprain
The objective of this study is to demonstrate the multiple-dose efficacy and safety of HKT-500 for the treatment of ankle sprain.
- Trial name
- NCT00927641
- Testing
- Ketoprofen Patch
- Where
- 25 sites in United States
- Volunteers
- 240 people
- Sponsor
- Hisamitsu Pharmaceutical Co., Inc.
Injury, Knee, Injury, Ankle
Prevention of Patellar and Achilles Tendinopathies in Youth Basketball
This study seeks to determine the prevalence of knee and ankle tendinopathies in youth basketball players, as well as determine the efficacy of a Basketball specific Neuromuscular training warm-up in reducing injuries.
- Conditions
- Injury, Knee, Injury, Ankle, Tendinopathy, Sports Injuries in Children
- Trial name
- NCT04363398
- Testing
- Comprehensive Follow-up, Standard Follow-up
- Where
- Canada
- Volunteers
- 441 people, healthy volunteers welcome
- Sponsor
- Sport Injury Prevention Research Centre
Ankle Injuries
Transcutaneous Oxygen Pressure of the Injured Ankle as Predictor of Postoperative Cutaneous Pain
This monocentric prospective observational pilot study aims to investigate if the measurement of TcPO2 can be used as a predictor of postoperative cutaneous pain in patients with ankle surgery.
- Trial name
- TAC (NCT04209582)
- Testing
- measurement of TcPO2 with skin electrode
- Where
- France
- Volunteers
- 39 people
- Sponsor
- Nantes University Hospital
Sprains and Strains
Kinesio Tape Effects on Ankle Proprioception
The aim of the present study was to establish whether Kinesio Tape (KT) on the ankle (Kase protocol for the lateral ankle ligament) improves Joint Position Sense (JPS) in healthy volunteers immediately after its application and…
- Trial name
- NCT01792908
- Testing
- Kinesio tape
- Where
- Spain
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Phantom Limb Pain, Phantom Pain
VR to Evaluate Phantom Limb Pain
The objective of this study is to develop a virtual rehabilitation system that can be used to effectively treat Phantom Limb Pain (PLP) within the research setting and for at-home use by individuals with upper and lower extremity…
- Conditions
- Phantom Limb Pain, Phantom Pain, Phantom Sensation, Phantom Limb Syndrome With Pain
- Trial name
- NCT05915065
- Testing
- Coapt Phantom Limb Pain Management System
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Shirley Ryan AbilityLab