Clinical trials: Wrinkles and Rhytides
Cheek Wrinkles
Safety and Effectiveness of Sculptra Aesthetic for Correction of Cheek Wrinkles
The study has been designed to evaluate the safety and effectiveness of Sculptra Aesthetic as a single regimen for correction of cheek wrinkles after changes in reconstitution and injection procedures compared to the approved…
- Trial name
- NCT04124692
- Testing
- Sculptra Aesthetic new dilution
- Where
- 13 sites in United States
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Face and Neck Wrinkles, Texture, Pigmentation
Lutronic Infini and LaseMD Systems in Combination Treatment
This is a prospective, multi-site, non-randomized study evaluating the safety and effectiveness of the Infini and LaseMD Systems for combination treatment in wrinkles, texture, and pigmentation of the face and/or neck.
- Trial name
- NCT03409965
- Testing
- Lutronic Infini System, Lutronic LaseMD System
- Where
- 2 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- CynosureLutronic
Hirsutism, Hypertrichosis
Enhanced Safety Aesthetic Laser System
The purpose of this study is to determine whether a new laser system provides better safety and efficacy than existing lasers in popular cosmetic procedures such as hair removal, treatment of cosmetically disturbing vascular…
- Conditions
- Hirsutism, Hypertrichosis, Telangiectases, Rhytides
- Trial name
- NCT00495443
- Testing
- Peterio
- Where
- Israel
- Volunteers
- 25 people
- Sponsor
- Scilex Ltd.
Laxity; Skin, Volume Deficiency in the Mid-Face
Prospective Clinical Evaluation of the Safety and Performance of the Aesthetic Medical Device MEC REGENERATE® (Injectable Recombinant Collagen-based Product)
Prospective, spontaneous, open-label pre-market clinical trial with a single injection session; monitoring visits at baseline and 60 days post-treatment.
- Conditions
- Laxity; Skin, Volume Deficiency in the Mid-Face, Wrinkles
- Trial name
- NCT07413445
- Testing
- Treatment with experimental device
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- 303 Pharma s.r.l.
Skin Wrinkling
A Study to Validate Cosmetic Outcome Scales Used to Rate Uneven Skin Color and Wrinkling
Skin chronically exposed to the sun may become damaged and then develop wrinkles and/or uneven skin color. The purpose of this research study is to evaluate a newly developed scale (grading tool) that rates wrinkles and uneven…
- Trial name
- NCT00114673
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Graceway Pharmaceuticals, LLC
Skin Laxity, Wrinkle
Clinical Study to Evaluate the Efficacy and Safety of Matrix Pro Treatment
This is a non-randomized, multi-center, open-label, prospective clinical trial evaluating clinical treatments with the Matrix Pro Applicator for the improvement of facial and/or submental and neck laxity.
- Conditions
- Skin Laxity, Wrinkle, Skin Condition
- Trial name
- NCT06726122
- Testing
- Profound Matrix
- Where
- 3 sites in Netherlands, United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Candela Corporation
Wrinkles, Rhytids
Evaluation of the Ulthera® System for Treatment of the Face and Neck
Up to 15 subjects will be enrolled. Enrolled subjects will receive one Ulthera® treatment on the face and neck. Follow-up visits will occur at 45, 90 and 180 days post-treatment.
- Conditions
- Wrinkles, Rhytids, Skin Laxity
- Trial name
- NCT01713907
- Testing
- Ulthera® Treatment
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Ulthera, Inc
Wrinkle
Study to Identify if Saie Beauty's Under Eye Concealer Works to Improve Under-Eye Skin Appearance and Reduce Imperfections
Saie Beauty has developed 'Hydrabeam Sheer Brightening Under Eye Concealer' that is specifically designed for improving under-eye skin health.
- Trial name
- NCT05231681
- Testing
- Saie Beauty's Hydrabeam Sheer Brightening Under Eye Concealer
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Saie Beauty
Facial Wrinkles
Multicenter Study of the Safety and Effectiveness of Dermal Filler, Belotero®.
This was a study to find out how an investigational product, Belotero, compares to a second product in people with facial wrinkles, such as nasolabial folds.
- Trial name
- NCT00876265
- Testing
- Belotero, Zyplast
- Where
- 6 sites in United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Merz North America, Inc.
Wrinkles, Scars
Pilot Evaluation of the Cynosure Potenza™ System for Treatment of Cosmetic Dermatologic Skin Conditions
The primary objective of this pilot study is exploratory investigation evaluating the Potenza microneedle fractional radiofrequency (RF) device and may be used in combination with the Icon intense pulsed light (IPL) device.
- Conditions
- Wrinkles, Scars, Stretch Marks, Pigmentation
- Trial name
- NCT05847530
- Testing
- Potenza, Icon
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cynosure, Inc.
Nasolabial Fold Wrinkles
BC-101 in Treatment of Nasolabial Fold Wrinkles
This is an open-label, single-arm, dose-escalating study to evaluate the safety and tolerability of BC-101 administered via subcutaneous/intradermal injection in the treatment of moderate to severe nasolabial folds.
- Trial name
- NCT05162326
- Testing
- BC-101
- Volunteers
- 9 people
- Sponsor
- Bright Cell, Inc.
Photoaging, Wrinkle
Same-Day Combination of VI Peel and Botox for Correction of Sun Damage, Fine Lines and Wrinkles
This study is being conducted to improve standards of care in the cosmetic treatment of sun damage, fine lines, and wrinkles. VI Peels® and Botox® have been used cosmetically to improve patient concerns as monotherapies.
- Conditions
- Photoaging, Wrinkle, Sun Damaged Skin
- Trial name
- NCT05162300
- Testing
- Same Day Intervention of VI Peel (Procedure) and Botulinum Toxin (Drug)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Vitality Institute Medical Products
Décolleté Wrinkles
Evaluation of the Effectiveness and Safety of Diluted RADIESSE® in the Treatment of Décolleté Wrinkles
Trial to confirm the effectiveness and demonstrate the safety of treatment with diluted Radiesse for correction of Décolleté Wrinkles.
- Trial name
- NCT05163353
- Testing
- Treatment with diluted Radiesse
- Where
- 9 sites in United States
- Volunteers
- 152 people
- Sponsor
- Merz North America, Inc.
Skin Aging, Facial Rhytides
AnteAGE Biosomes With Radiofrequency Microneedling for Facial Skin Rejuvenation
This prospective, randomized controlled study evaluated the efficacy and tolerability of AnteAGE Biosome Solution used in conjunction with facial radiofrequency microneedling.
- Conditions
- Skin Aging, Facial Rhytides, Skin Tone
- Trial name
- NCT07849556
- Testing
- AnteAGE Biosome Treatment Solution, Radiofrequency Microneedling, AnteAGE Homecare Regimen
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cellese Inc.
Skin Aging
A 56-Day Exploratory Study of NatureU® Mind Care BeautyU Caps on Skin Aging Parameters
This was a 56-day, single-center, open-label, single-arm exploratory study evaluating within-participant changes in skin-aging parameters after daily oral intake of NatureU® Mind Care BeautyU Caps in adult women.
- Trial name
- NUAA (NCT07571629)
- Testing
- NatureU® Mind Care BeautyU Caps
- Where
- China
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- OmniSolutions Laboratory Holdings Limited
Nasolabial Folds
Evaluation of Pain With Lidocaine-Mixed Radiesse® Injectable Dermal Filler
To assess pain during nasolabial fold treatment using Radiesse® Injectable Dermal Filler mixed with lidocaine.
- Trial name
- NCT01012661
- Testing
- Radiesse® Injectable Dermal Filler Mixed with Lidocaine, Radiesse® Injectable Dermal Filler without Lidocaine
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Merz North America, Inc.
Nasolabial Fold
Post Market Clinical Follow up Evaluating the Performance and Safety of Juläine(TM) on Nasolabial Fold Wrinkles
The goal of this post marketing study is to verify clincal performance and safety of CE-marked device Juläine. The main objective is to evaluate device performance when used as intended for augmentation of shallow to deep…
- Trial name
- NCT06471933
- Testing
- Juläine
- Where
- 2 sites in Spain, Sweden
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Nordberg Medical AB
Wrinkles, Scars
Study of a Novel Microlens Array Device for Skin Rejuvenation
A single-center prospective, open-label uncontrolled pilot study. Subjects will receive laser treatments and will be followed at 12 weeks post-final treatment.
- Trial name
- NCT02888626
- Testing
- Microlens Array
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Wrinkle, Aging
Evaluation of Performance and Safety of INNEA and INNEA AQUA for the Treatment of Cheek and décolletage Wrinkles
A Post-Market, Single-arm, Confirmatory Interventional Clinical Investigation to evaluate the Performance and Safety of INNEA and INNEA AQUA for the treatment of cheek and décolletage wrinkles
- Trial name
- NCT07331181
- Testing
- Innea, Innea Aqua
- Where
- 3 sites in Italy
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Innate srl
Facial Wrinkles and Rhytides Reduction
Clinical Study to Determine Safety and Efficacy of FPlus for Wrinkle Treatment
Patient demand for non-surgical, non-invasive, and no-downtime wrinkle and rhytides treatment procedures has grown dramatically over the past decade as new treatments and technologies have been introduced.
- Trial name
- NCT01559233
- Testing
- FPlus RF device for wrinkles and rhytide reduction
- Where
- Canada
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Invasix