Clinical trials: Wrinkles and Rhytides
Facial Skin Aging and Wrinkle Severity
Antioxidant Nutrition and Facial Exercise for Skin Aging
This randomized controlled trial will evaluate the effects of a 12-week combined antioxidant-rich nutrition and facial exercise program on skin quality and wrinkle severity in middle-aged women.
- Trial name
- NCT07792447
- Testing
- Combined Antioxidant Nutrition and Facial Exercise Program
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Zakho
Facial Wrinkles and Rhytides Reduction
Clinical Study to Determine Safety and Efficacy of FPlus for Wrinkle Treatment
Patient demand for non-surgical, non-invasive, and no-downtime wrinkle and rhytides treatment procedures has grown dramatically over the past decade as new treatments and technologies have been introduced.
- Trial name
- NCT01559233
- Testing
- FPlus RF device for wrinkles and rhytide reduction
- Where
- Canada
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Invasix
Nasolabial Folds
Evaluate Efficacy, Safety & Subject Satisfaction of Pain Management With Pliaglis® Cream for Dermal Filler Injections
Pliaglis® Cream versus compounded topical anesthetic for pain management during Restylane® injections for the correction of nasolabial folds.
- Trial name
- NCT00716443
- Testing
- tetracaine 7% / lidocaine 7% cream (Pliaglis® Cream), benzocaine 20% / lidocaine 6% / tetracaine 4% ointment
- Where
- 4 sites in United States
- Volunteers
- 51 people
- Sponsor
- Galderma R&D
Forehead/Glabellar Rhytid Complexes
Treatment of Forehead/Glabellar Rhytide Complex With Combination Botulinum Toxin A and Hyaluronic Acid Versus Botulinum Toxin A Injection Alone
The objective of this study is to determine whether the use of botulinum toxin (Dysport ®) in conjunction with a hyaluronic acid filler (Restylane®) will improve the appearance of wrinkles on the forehead and glabella (area…
- Trial name
- NCT01186835
- Testing
- Combination Botulinum Toxin A and Hyaluronic Acid, Botulinum Toxin A
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Lipoatrophy, Aging
Safety Study of Antria Cell Preparation Process to Enhance Facial Fat Grafting With Adipose Derived Stem Cells
The primary purpose of this study is to demonstrate the safety of injecting the Stromal Vascular Fraction (SVF) [containing Adipose Derived Stem Cells (ADSCs)] enriched fat grafts into regions of the face that require…
- Conditions
- Lipoatrophy, Aging, Wrinkles
- Trial name
- NCT01828723
- Testing
- SVF
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Antria
Periorbital Wrinkles
Evaluation of the Safety and Performance of Epicare for the Treatment of Periorbital Wrinkles
This is a prospective, interventional, evaluator-blinded, multi-center clinical study designed to assess the safety and performance of the Epicare fractional nano-thulium (Tm:YAP 1938 nm) laser system for the treatment of…
- Trial name
- NCT07114562
- Testing
- Epicare
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Laser team Ltd
Nasolabial Folds
Evaluation of Pain With Lidocaine-Mixed Radiesse® Injectable Dermal Filler
To assess pain during nasolabial fold treatment using Radiesse® Injectable Dermal Filler mixed with lidocaine.
- Trial name
- NCT01012661
- Testing
- Radiesse® Injectable Dermal Filler Mixed with Lidocaine, Radiesse® Injectable Dermal Filler without Lidocaine
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Merz North America, Inc.
Wrinkles or Damaged Skin Condition
An Open Label Study to Evaluate the Efficacy of Airgent in Treating Damaged and Wrinkled Skin
The primary objective of this study is to Evaluate the effectiveness of treatment of wrinkles or damaged skin with the Airgent device.
- Trial name
- NCT00811161
- Testing
- Airgent
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- PerfAction Ltd.
Wrinkle
Robotic Mechanical Coring for the Treatment of Moderate to Severe Facial Wrinkles
This study is a prospective, up to 4 center study of the safety and efficacy of mechanical coring with skin closure of cored holes, intended for the improvement in the appearance of wrinkles of the cheeks in up to 70 subjects…
- Trial name
- NCT05091788
- Testing
- Venus Aime
- Where
- 2 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Venus Concept
Facial Wrinkles
Efficacy and Safety of a Cutaneous Formulation of Gonyautoxin 2/3 (GTX 2/3) for the Treatment of Facial Wrinkles
The main objective of the trial is to determine whether the current topical formulation of GTX 2/3 reduces the wrinkling of the skin (crow's feet) after a single application Other evaluation criteria include: safety assessment…
- Trial name
- NCT00734786
- Testing
- Wrinkle cream application
- Where
- Argentina
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Phytotox SA
Glabellar Frown Lines
Duration of Botox Using OLD Versus COLD for Treatment of Glabellar Lines
This is a blinded, randomized study in the US to compare the duration response of two different concentrations of BOTOX in healthy female subjects with moderate to severe dynamic glabellar lines on maximum frown.
- Trial name
- NCT05083286
- Testing
- OnabotulinumtoxinA
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Clinical Testing of Beverly Hills
Nasolabial Folds
Radiesse® Injectable Dermal Filler for the Treatment of Nasolabial Folds in Persons of Color
Post marketing study to assess the likelihood of hypertropic scarring, keloid formation and hyper- or hypopigmentation in patients with Fitzpatrick Skin Types IV, V, and VI receiving nasolabial fold treatment with Radiesse®…
- Trial name
- NCT01012388
- Testing
- Radiesse® Injectable Dermal Filler
- Where
- 5 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Merz North America, Inc.
Nasolabial Folds
Safety Study That Compares Perlane to Perlane With Lidocaine (Perlane-L) While Correcting Wrinkles in the Area Around Your Nose
Safety study that compares Perlane to Perlane with Lidocaine while correcting wrinkles in the area around your nose.
- Trial name
- NCT00823069
- Testing
- Perlane and Perlane-L
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- Medicis Global Service Corporation
Cheek, Wrinkle
Open Label Extension for 43USSA1812
To evaluate long-term safety and effectiveness data of Sculptra Aesthetic beyond the Month 12 duration of the pivotal study 43USSA1812 (NCT04124692) to help characterize the long-term safety and effectiveness profile of the more…
- Trial name
- NCT04595331
- Testing
- Sculptra Aethestic reconsituted with 8ml Sterile Water for Injection
- Where
- 13 sites in United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Healthy, Wrinkle
Safety and Efficacy Study of Vasu Facial Beauty Oil
This is an open-label, single-arm, single-center, proof-of-concept, exploratory, safety and efficacy, clinical study of a Vasu Facial Beauty Oil in healthy adult human subjects.
- Conditions
- Healthy, Wrinkle, Dry Skin, Skin Pigment
- Trial name
- NCT05646953
- Testing
- Facial Beauty Oil
- Where
- India
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- NovoBliss Research Pvt Ltd
Wrinkle
Efficacy and Safety of 675-nm Laser for Dorsal Hand Rejuvenation
This study aimed to evaluate efficacy and safety of 675-nm laser for dorsal hand rejuvenation in Thai patients. Twenty-six subjects aged 50 to 65 years diagnosed with wrinkle and solar lentigines on both dorsums of hands were…
- Trial name
- NCT06486727
- Testing
- Redtouch
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Wrinkle, Pigmentation
Device for Improving Skin Quality and Texture on the Face and Neck
The goal of this clinical trial is to investigate the effect of the BTL-785F device (with BTL-785-4-4 tip on BTL-785-4 applicator) on the improvement of skin quality and texture on the face and neck in healthy adult volunteers.
- Conditions
- Wrinkle, Pigmentation, Skin Laxity, Skin Scarring
- Trial name
- NCT06645366
- Testing
- Treatment with BTL-785F
- Where
- 3 sites in United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Photodamage of the Face, Anti Aging
Evaluation of the Efficacy and Tolerability of the LED Mask With or Without the Serum Formula on the Signs of Facial Photodamage .
Main objective : To evaluate the anti-aging effectiveness of the LED mask alone on at least one studied anti-aging parameters (including some targeted wrinkles) after 3 months versus baseline Secondary objectives: Anti-aging…
- Trial name
- NCT07661004
- Testing
- MASK LED, LED MASK AND COSMETIC FORMULA
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- L'Oreal
Cheek Wrinkles, Midface Contour Deficiencies
A Study to Evaluate the Safety and Effectiveness of GP0112 for Cheek Augmentation and Correction of Midface Contour Deficiencies
This is a randomized, evaluator-blinded, parallel group, comparator-controlled, multicenter study to evaluate the safety and effectiveness of GP0112 for cheek augmentation and correction of midface contour deficiencies.
- Trial name
- NCT07909421
- Testing
- GP0112, Juvéderm Voluma XC
- Where
- China
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Peri-oral Wrinkles
Study of Restylane and Perlane in the Correction of Peri-Oral Wrinkles
This is an open-label study to assess safety using Restylane and Perlane in the correction of facial wrinkles.
- Trial name
- NCT00977704
- Testing
- Restylane and Perlane
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Medicis Global Service Corporation