Clinical trials: Young Adults
Healthy Young Adults, Healthy Adult Participants
Foam Rolling and Blood Pressure
Foam rolling (FR) has emerged as a widely adopted modality among rehabilitation practitioners and physically active populations.
- Conditions
- Healthy Young Adults, Healthy Adult Participants, Healthy Participants, Normotensive
- Trial name
- NCT07520474
- Testing
- Foam Rolling Intervention (FR)
- Where
- Italy
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Stress, Physiological, Stress, Psychological
Wise Interventions and Responses to Stress
This study compares the effects of two wise interventions (implicit theory of personality intervention and implicit theory of personality intervention plus self-affirmation) with a control condition in the stress responses of…
- Conditions
- Stress, Physiological, Stress, Psychological, Social Stress, Depression
- Trial name
- ITP-RSA (NCT04786496)
- Testing
- ITP+SA Wise intervention, ITP Wise intervention, Control condition
- Where
- Spain
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University of Deusto
Autism Spectrum Disorder High-Functioning
A Peer-mediated Vocational Social Skills Program for Young Adults With Autism
The Assistive Social Skills and Employment Training program (ASSET) is an occupationally-based, work-related social skills intervention, designed to address the pre-employment and mental health needs of young adults with…
- Trial name
- NCT04468620
- Testing
- Assistive Soft Skills & Employment Training (ASSET)
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Florida Gulf Coast University
Drinking, Alcohol, Drinking Behavior
Inhibitory Control Smartphone App
The proposed study will address a critical knowledge gap: there are no evidence-based smartphone apps for reducing young adult drinking.
- Trial name
- NCT04243759
- Testing
- Control App Version, Standard App Version, Experimental, Feedback App Version
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Florida
Skin Neoplasms
A Tailored Internet Intervention to Reduce Skin Cancer Risk Behaviors Among Young Adults
Skin cancer is the most common cancer in the US, with over a million new cases diagnosed yearly. Young adults are increasingly at risk of melanoma.
- Trial name
- UV4me (NCT02147080)
- Testing
- UV4me, Skin Cancer Foundation website
- Where
- United States
- Volunteers
- 1,234 people, healthy volunteers welcome
- Sponsor
- Fox Chase Cancer Center
Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS)
Reduced-Intensity Conditioning (RIC) and Myeloablative Conditioning (MAC) for HSCT in AML/MDS
The purpose of this study is to compare safety and efficacy of reduced-intensity conditioning and myeloablative conditioning regimens prior to HSCT in high-risk AML/MDS pediatric and young adult patients.
- Conditions
- Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS), Hematopoietic Stem Cell Transplant (HSCT)
- Trial name
- NCT02626715
- Testing
- Reduced-Intensity Conditioning Regimen, Myeloablative Conditioning Regimen
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Randy Windreich
Sarcoma, Wilm's Tumor
Phase I Study of Ipilimumab (Anti-CTLA-4) in Children and Adolescents With Treatment-Resistant Cancer
This study will examine the safety and efficacy of ipilimumab-an experimental cancer treatment drug used to boost immune response-in children, adolescents, and young adults.
- Conditions
- Sarcoma, Wilm's Tumor, Lymphoma, Neuroblastoma
- Trial name
- NCT01445379
- Testing
- Ipilimumab
- Where
- 3 sites in United States
- Volunteers
- 33 people
- Sponsor
- National Cancer Institute (NCI)
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer
This phase III trial compares the effect of giving triptorelin vs no triptorelin in preventing ovarian damage in adolescents and young adults (AYAs) with cancer receiving chemotherapy with alkylating agents.
- Trial name
- NCT06513962
- Testing
- Best Practice, Biospecimen Collection, Electronic Health Record Review
- Where
- 206 sites in United States, Canada
- Volunteers
- 60 people
- Sponsor
- Children's Oncology Group
Dietary Supplementation, Healthy Vollunteer
Effect of β-alanine Supplementation and Training on Ergogenic Measures and Plasma Metabolites in Untrained Young Adults
This study enrolled untrained young adults to evaluate the effects of β-alanine supplementation combined with a structured exercise training program.
- Trial name
- NCT07404540
- Testing
- β-Alanine
- Where
- Hungary
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Tobacco-Related Carcinoma
A Novel Mobile Health Intervention for Improving Tobacco Cessation Among Young Adults
Tobacco use is the leading cause of preventable cancer deaths. Among young adults, approximately 1 in 5 use commercial nicotine and tobacco products, putting them at risk of developing nicotine addiction and long-term health…
- Trial name
- NCT07571018
- Testing
- Smartphone app-based Intervention, Communication intervention, Survey Administration
- Where
- 2 sites in United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Diet Quality, Young Adult Health
Young Adult Food Messaging Experiment
The primary objective of this study is to identify the food counter-marketing messages (i.e., messages that describe deceptive marketing tactics used by food companies) that are perceived as most effective among young adults.
- Conditions
- Diet Quality, Young Adult Health, Communication
- Trial name
- NCT07768462
- Testing
- Lying about unhealthy foods being healthy, Engineering foods to be addictive, Targeting groups
- Where
- United States
- Volunteers
- 645 people, healthy volunteers welcome
- Sponsor
- Stanford University
Cancer
Nab-paclitaxel in Combination with Gemcitabine for Pediatric Relapsed and Refractory Solid Tumors
This is a research study for people who have a solid tumor that was not effectively treated by conventional therapy or for which there is no known effective therapy.
- Trial name
- NCT03507491
- Testing
- Gemcitabine, Nab-paclitaxel
- Where
- 4 sites in United States
- Volunteers
- 24 people
- Sponsor
- Emory University
Schizophrenia, Schizoaffective Disorder
Lifestyle Intervention for Young Adults With Serious Mental Illness
This is a four year project evaluating the effectiveness of a group-based lifestyle intervention (PeerFIT) supported by mobile health (mHealth) technology and social media compared to Basic Education in fitness and nutrition…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Major Depressive Disorder
- Trial name
- NCT02815813
- Testing
- PeerFIT, BEAT
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Osteosarcoma
A Study to Compare the Efficacy and Safety of Ifosfamide and Etoposide With or Without Lenvatinib in Children, Adolescents and Young Adults With Relapsed and Refractory Osteosarcoma
This Is a Multicenter, Randomized, Open-Label, Parallel-Group, Phase 2 Study to Compare the Efficacy and Safety of Lenvatinib in Combination with Ifosfamide and Etoposide Versus Ifosfamide and Etoposide in Children, Adolescents…
- Trial name
- NCT04154189
- Testing
- Lenvatinib, Ifosfamide, Etoposide
- Where
- 84 sites in United States, Australia and 19 more
- Volunteers
- 81 people
- Sponsor
- Eisai Inc.
Metabolically Healthy Obesity, Intermittent Fasting
Healthy vs Unhealthy Obesity: Mehanistic Insights and Effects of Time-Restricted Eating
Obesity-related cardiometabolic diseases are now a leading cause of death worldwide. These diseases result from a dysfunctional adipose tissue (AT) that induces inflammation, insulin resistance and altered endocrine function.
- Trial name
- NCT05136313
- Testing
- Time-restricted eating
- Where
- Chile
- Volunteers
- 53 people
- Sponsor
- Instituto de Nutrición y Tecnología de los Alimentos
Hamstring Tightness
Effects of Lumbosacral Mobility Program on Tight Hamstrings
The study will be randomized controlled trial to determine the effects of lumbosacral mobility program on muscle length in sedentary young adults with tight hamstrings.
- Trial name
- NCT05393960
- Testing
- Lumbosacral manual therapy mobilization, lumber mobility exercises and home based self strechings program., home based self strechings program only.
- Where
- Pakistan
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Riphah International University
B-cell Acute Lymphoblastic Leukemia
Study of Tisagenlecleucel in Chinese Pediatric and Young Adult Subjects With Relapsed or Refractory B-cell ALL
This is a single arm, multi-center, phase II study to evaluate the efficacy and safety of tisagenlecleucel in Chinese pediatric and young adult subjects with relapsed or refractory B-cell acute lymphoblastic leukemia (ALL)
- Trial name
- NCT04156659
- Testing
- Tisagenlecleucel
- Sponsor
- Novartis Pharmaceuticals
Relapsed Hematologic Malignancy, Refractory Hematologic Malignancy
International Leukemia Target Board
The iLTB is a proof-of-concept initiative for children with r/r hematological malignancies, in which available treatment options will be prioritized by actionable events in a harmonized and uniform setting across Europe by a team…
- Trial name
- iLTB (NCT05270096)
- Testing
- Advice
- Where
- 7 sites in Belgium, Denmark and 5 more
- Volunteers
- 600 people
- Sponsor
- Princess Maxima Center for Pediatric Oncology
Exercise, Heat Strain
Effect of Exercise and Heat Stress on Acute Cardiometabolic Adaptations in Healthy Young Adults
Life in space is completely void of physical and environmental stress. It is well known that living things need regular physical stress (e.g. exercise) to remain strong, functional and healthy.
- Conditions
- Exercise, Heat Strain, Control Condition
- Trial name
- NCT06872762
- Testing
- Exercise, Heat strain
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Northern Arizona University
rTMS Stimulation, Autonomy
Repetitive Transcranial Magnetic Stimulation Primed Self-controlled Practice on Motor Learning
This study aims to investigate the additive effects of combining self-controlled practice with repetitive transcranial magnetic stimulation (rTMS) pretreatment on motivation enhancement and motor learning performance in healthy…
- Conditions
- rTMS Stimulation, Autonomy, Healthy Young Adults
- Trial name
- NCT07197346
- Testing
- rTMS - cTBS (Continuous Theta-Burst Stimulation), Self-controlled (autonomy), Yoked Practice
- Where
- Taiwan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
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