Clinical trials: Young Adults
Femoral Neck Fractures
Fixation Using Alternative Implants for the Treatment of Hip Fractures (FAITH-2)
The purpose of this study is to determine the impact of surgical fixation (cancellous screws versus sliding hip screws) and biologic intervention (Vitamin D versus placebo) on patient important outcomes.
- Trial name
- FAITH-2 (NCT01908751)
- Testing
- Sliding Hip Screw, Cancellous Screws, Vitamin D
- Where
- 20 sites in United States, Australia and 1 more
- Volunteers
- 91 people
- Sponsor
- McMaster University
Neuroblastoma Recurrent
Multimodal Molecular Targeted Therapy to Treat Relapsed or Refractory High-risk Neuroblastoma
Children, adolescents and young adults with high risk relapsed or treatment refractory neuroblastoma (rNB) represent a group of patients with dismal prognosis for whom a recommended standard salvage therapy is currently not…
- Trial name
- RIST-rNB-2011 (NCT01467986)
- Testing
- Dasatinib, Rapamycin, Irinotecan
- Where
- Germany
- Volunteers
- 130 people
- Sponsor
- University of Regensburg
Healthy
Metabolic Availability of Methionine From Chickpeas in Adult Men
The research study is being done so we can determine the quality of the protein present in Canadian chickpeas. Amino acids are the building blocks of protein and protein quality is determined by the amount of amino acids present…
- Trial name
- NCT03339154
- Testing
- Dietary Intakes
- Where
- Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Cancer
Promoting Quality of Life Among Young Adult Cancer Survivors
This study expands on a prior pilot study to refine the intervention messaging to focus on goal-oriented thinking, include a coach, and extend the intervention to a larger sample of young adult cancer survivors (aged 18-39 years)…
- Trial name
- NCT03446105
- Testing
- App-based behavioral intervention, Attention control group
- Where
- 2 sites in United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Emory University
Pediatric Cancer, Solid Tumors
A Phase I Study of Lyso-thermosensitive Liposomal Doxorubicin and MR-HIFU for Pediatric Refractory Solid Tumors
This study is looking to determine the maximum tolerated dose (MTD) and recommended phase 2 dose (RP2D) of lyso-thermosensitive liposomal doxorubicin (LTLD) administered in combination with MR-HIFU in children with…
- Conditions
- Pediatric Cancer, Solid Tumors, Rhabdomyosarcoma, Ewing Sarcoma
- Trial name
- NCT02536183
- Testing
- Magnetic resonance high intensity focused ultrasound, Lyso-thermosensitive liposomal doxorubicin
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- AeRang Kim
Hip Dysplasia, Femoroacetabular Impingement
Cam Type FAI is a Cause of Hip Pain in the Young Adult and a Precursor to OA
An abnormally formed hip joint (cam deformity) is a major cause of osteoarthritis (OA). Individuals may not experience any symptoms until OA is severe due to extensive cartilage loss and changes in underlying bone.
- Conditions
- Hip Dysplasia, Femoroacetabular Impingement, Osteoarthritis
- Trial name
- NCT04080466
- Testing
- Low-dose CT Scan, Blood/Urine Collection, Patient Reported Questionnaires
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Vaping
Responses to Message Source and Presentation Using Psychophysiology
The goal of this clinical trial is to use psychophysiological methods to test the effects of a message source (expert and peer) and message presentation types (one-sided and two-sided) to identify the optimal message type for…
- Trial name
- NCT06269003
- Testing
- Expert, one-sided, Expert, two-sided, Peer, one-sided
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Solid Tumours
Pazopanib Paediatric Phase II Trial Children's Oncology Group (COG) in Solid Tumors
The study design was an open-label Phase II pediatric clinical study. The purpose of Study X2203 was to identify any efficacy signal in subjects with the disease subtypes under study, when treated with pazopanib monotherapy.
- Trial name
- NCT01956669
- Testing
- Pazopanib
- Where
- 31 sites in United States, Canada and 5 more
- Volunteers
- 57 people
- Sponsor
- Novartis Pharmaceuticals
Healthy
Evaluation of Bacillus Subtilis R0179 in Healthy Young Adults
The purpose of this study is to evaluate the effect of three doses of the probiotic B. subtilis (Bacillus subtilis R0179) delivered in capsules on gastrointestinal and general wellness in healthy young adults, survival through…
- Trial name
- NCT01802151
- Testing
- B. subtilis R0179
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University of Florida
Periodontitis, Aggressive
The Effect of Non-Surgical Periodontal Treatment on Systemic Inflammatory Markers and Lipid Profile in Young Adults With Severe Periodontitis
The goal of this clinical study was to evaluate whether non-surgical treatment for severe periodontitis (gum disease) could improve body-wide inflammation and blood fat levels in young adults with severe periodontitis.
- Trial name
- NCT07526883
- Testing
- Non-surgical periodontal treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istanbul University
AML, ALL
Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant Disorders
This is a single-arm study to investigate 1-year treatment related mortality (TRM) in patients with life threatening non-malignant and malignant hematologic disorders who do not have a matched related donor for allogeneic…
- Conditions
- AML, ALL, MDS, MPD Withou Myelofibrosis
- Trial name
- NCT04644016
- Testing
- Clofarabine, Fludarabine, Busulfan
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Alzheimer Disease
Prospective Memory Imaging
The purpose of this study is to investigate prospective merory (memory of intentions) in healthy controls and in aMCI (amnestic Mild Cognitive Impairment) and AD (Alzheimer Disease) patients.
- Trial name
- IMPRO (NCT01638884)
- Testing
- Memory assessment, Structural MRI, Functional MRI
- Where
- 3 sites in France
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Type 2 Diabetes Mellitus (T2DM), Diabetes-related Distress
Digital Self-Management Education and Support for Young Adults With Type 2 Diabetes (DSMESYAT2DM)
This randomized controlled trial will evaluate the effect of a nurse-led digital self-management education and support program on self-management behaviors, glycemic control, and diabetes-related distress in young adults with…
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Diabetes-related Distress, Diabetes Distress
- Trial name
- DSMESYAT2DM (NCT07325838)
- Testing
- Digital Nurse-Led DSMES Program, Usual Care Plus Standard Digital Education
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Recep Turan
Acute Lymphoblastic Leukemia
ALL2008 Protocol for Childhood Acute Lymphoblastic Leukemia (ALL) - 6MP Consolidation Therapy
The purpose of this study is to increase the fraction of patients, who become MRD-negative during consolidation for the non-HR ALL group through individualized intensification of the 6MP-dosage days 30-85.
- Trial name
- ALL2008con (NCT00816049)
- Testing
- 6MPindividualized, 6MPfixed
- Where
- 6 sites in Denmark, Finland and 3 more
- Volunteers
- 775 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Hiv, Minority Stress
Developing an Online Mindfulness-based Intervention to Reduce Minority Stress and HIV Risk Among Young Adult MSM - Aim 3
The overall aim of the research study is to develop and test a mindfulness-based program for young adult gay, bisexual, and queer men at risk for HIV (Brown University IRB approved protocol #2004002698).
- Conditions
- Hiv, Minority Stress, Mental Health Wellness 1
- Trial name
- MBQR (NCT05855655)
- Testing
- Mindfulness-Based Queer Resilience (MBQR)
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Brown University
Anxiety, Mental Health
Improv Comedy to Reduce Anxiety and Improve Mental Well-Being in Young Chinese Adults in Hong Kong
The goal of this clinical trial is to learn if improv comedy helps reduce anxiety symptoms and improve mental well-being in Chinese young adults in Hong Kong. The main questions it aims to answer are: 1.
- Trial name
- NCT07737821
- Testing
- Improv Against Anxiety (IAA)
- Where
- Hong Kong
- Volunteers
- 150 people
- Sponsor
- The University of Hong Kong
Systemic Lupus
Use of Social Media to Improve Medication Adherence in Adolescents and Young Adults With Systemic Lupus
The goal of this study was to examine the effect of an online educational program with and without a social media experience.The primary goal of this study was to determine whether medication adherence would be improved by having…
- Trial name
- NCT03218033
- Testing
- Social Media
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Infections, Papillomavirus
Human Papillomavirus Vaccine Safety & Immunogenicity Trial in Healthy Young Adult Women With HPV Vaccine (GSK1674330A)
Infection with human papillomavirus (HPV) has been clearly established as the central cause of cervical cancer. Indeed, certain oncogenic types of HPV can infect the cervix (part of the uterus or womb).
- Trial name
- NCT00478621
- Testing
- GSK Biologicals' HPV vaccine (GSK1674330A), Cervarix TM
- Where
- 3 sites in Belgium
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Sunburn
Randomized Trial of a Sun Safety Intervention for Young Adults
The goal of this randomized controlled trial is to test the efficacy of a dissonance induction intervention compared to a control group on tanning in 278 young adult tanners. The primary outcome will be tanning at 3-months.
- Trial name
- NCT07751406
- Testing
- Healthy Skin, Healthy Lifestyle
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Bioavailability, Kinetics
Bioavailability of Aronia Melanocarpa
The main objective of this study is to study the bioavailability and kinetics of acute Aronia Melanocarpa supplementation in healthy young (18-35 years) and older adults (55-75 years) adults.
- Trial name
- NCT06306911
- Testing
- Aronia Melanocarpa extract
- Where
- Netherlands
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
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