Clinical trials: Zenker Diverticulum
Achalasia, Paraesophageal Hernia
Minimally Invasive Surgery of the Gastro-esophageal Junction
This study will assess short and long term outcomes of individuals undergoing minimally invasive surgery of the gastro-esophageal junction (MISGEJ).
- Conditions
- Achalasia, Paraesophageal Hernia, GERD, Epiphrenic Diverticula
- Trial name
- MISGEJ (NCT01799967)
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Ottawa Hospital Research Institute
Laryngopharyngeal Reflux, Zenker's Diverticulum
Laryngopharyngeal Reflux Before and After Cricopharyngeal Myotomy
The purpose of this study is to see if people with reflux with a Zenker's diverticulum have increased reflux into the throat following a cricopharyngeal myotomy.
- Trial name
- NCT01880892
- Testing
- Cricopharyngeal myotomy, PH probe Testing
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Mayo Clinic
Zenker Diverticulum, Minimally Invasive Surgical Procedures
Minimally Invasive Endoscopic Treatment of Zenker's Diverticulum Comparing LigaSureTM vs SB-Knife.
The main purpose of this trial is to evaluate two devices used in the treatment of Zenker Diverticulum using flexible endoscopy (LigaSure and SB-knife).
- Conditions
- Zenker Diverticulum, Minimally Invasive Surgical Procedures, Endoscopy
- Trial name
- NCT04660214
- Testing
- septotomy
- Where
- Spain
- Volunteers
- 85 people
- Sponsor
- Hospital del Rio Hortega
Zenker Diverticulum
A New Treatment for Zenker's Diverticulum-submucosal Tunneling Endoscopic Septum Division
Zenker's Diverticulum (ZD) is a sac-like outpouching of the lining of the esophageal wall at the upper esophagus. It is a rare disease typically seen in the middle-aged and older adults.
- Trial name
- STESD (NCT03125733)
- Testing
- Submucosal tunneling endoscopic septum division
- Where
- 2 sites in United States, China
- Volunteers
- 20 people
- Sponsor
- Shanghai Zhongshan Hospital
Zenker Diverticulum, Progressive Dysphagia
Cricopharyngeal Dysfunction and Esophageal Diverticulum
Patients undergoing open transcervical or endoscopic approach in which a laser or stapler is used to divide the common wall between the diverticulum and esophagus, or who are not surgical candidates but agree to follow-up.
- Conditions
- Zenker Diverticulum, Progressive Dysphagia, Pharyngoesophageal Diverticulum
- Trial name
- NCT03187925
- Testing
- open, transcervical versus rigid endoscopic treatment
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of Cincinnati
Zenker Diverticulum
Evaluation of Peroral Endoscopic Myotomy to Treat Zenker's Diverticulum
This is a multicenter investigator-initiated trial between Baylor-Scotts \& White (BSW) and Methodist Health System (MHS). This study will be conducted via a retrospective review and a prospective patient registry.
- Trial name
- ZPOEM (NCT05157984)
- Testing
- ZPOEM
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Methodist Health System
Zenker Diverticulum
Endoscopic Treatment for Zenker's Diverticulum
Zenker's diverticulum (ZD) is a rare benign condition, due to an acquired sac-like outpouching of the mucosa and submucosa layers originating from the pharyngoesophageal junction.
- Trial name
- NCT03948438
- Testing
- Endoscopic septotomy
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- Istituto Clinico Humanitas
Gastrointestinal Neoplasia, Hirschsprung's Disease
Prospective Evaluation of the Efficacy and Safety of Submucosal Endoscopy
To test the idea that submucosal endoscopy is effective and safe for endoscopic myotomy, endoscopic submucosal dissection, and access for tissue acquisition and resection.
- Conditions
- Gastrointestinal Neoplasia, Hirschsprung's Disease, Esophageal Obstruction, Gastroparesis
- Trial name
- NCT03626350
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Colorado, Denver
Zenker Diverticulum
Endoscopic Treatment of Zenker's Diverticulum (ZENKTUN)
Prospective comparative observational study in numerous reference centers in France, comparing Tunnelization (Z-POEM) versus Non-Tunnelization Techniques according to the usual practices.
- Trial name
- NCT06594718
- Testing
- Endoscopic diverticulotomy with Z-POEM, Endoscopic diverticulotomy using a non-tunnelization technique
- Volunteers
- 128 people
- Sponsor
- Société Française d'Endoscopie Digestive
Zenker Diverticulum, Diverticulum, Esophago-Pharyngeal
Comparison of Zenker's Diverticulum Treatment Using Peroral Endoscopic Myotomy and Flexible Endoscopy Septotomy.
The Zenker's or pharyngo-esophageal diverticulum is an acquired sac-like outpouching of the mucosa and submucosa layers located dorsally at the pharyngoesophageal junction through Killian's dehiscence.
- Conditions
- Zenker Diverticulum, Diverticulum, Esophago-Pharyngeal, Diverticulum, Esophageal, Dysphagia
- Trial name
- ZIPPY (NCT04514042)
- Testing
- Peroral endoscopic myotomy, Flexible endoscopic septotomy
- Where
- Poland
- Volunteers
- 165 people
- Sponsor
- Maria Sklodowska-Curie National Research Institute of Oncology
Zenker Diverticulum, Polyp of Colon
Advanced Endo-therapeutic Procedure : Registry-based Observational Study
Advanced therapeutic endoscopy procedures are of increasing importance to provide minimal invasive treatment for GI diseases. The Centre Hospitalier de l'Université de Montréal as tertiary university center is dedicated to…
- Conditions
- Zenker Diverticulum, Polyp of Colon, Colo-rectal Cancer
- Trial name
- AE Registry (NCT04117100)
- Testing
- Polypectomy or myotomy
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Esophageal Stricture, Eosinophilic Esophagitis
EndoFLIP Use in Upper GI Tract Stenosis
The purpose of this study is to investigate the use of a functional luminal imaging probe to characterize benign esophageal luminal strictures before and after dilation and identify predictors of response to therapy.
- Conditions
- Esophageal Stricture, Eosinophilic Esophagitis, Zenkers Diverticulum, Schatzki Ring
- Trial name
- EndoFLIP (NCT02354716)
- Testing
- EndoFLIP
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Pennsylvania
Achalasia, Esophageal Spasm, Diffuse
Prospective Evaluation of the Clinical Utility of Peroral Endoscopic Myotomy for Gastrointestinal Motility Disorders
This is prospective data recording study. All patients will receive standard medical care and no experimental interventions will be performed.
- Conditions
- Achalasia, Esophageal Spasm, Diffuse, Gastroparesis, Swallowing Disorder
- Trial name
- POEM (NCT05905016)
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- AdventHealth
Zenker Diverticulum
Evaluation of Endoscopic Treatment of Zenker's Diverticulum Using LigaSure
The primary objective of this study is to evaluation the success of endoscopic treatment of Zenker's diverticulum using a LigaSure device (thermal fusion of vessels) via a measure of swallowing function at 12 months post-surgery.
- Trial name
- ZENKER LS (NCT01739426)
- Testing
- Repair w/LigaSure
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes