Clinical trials: Zinc Deficiency
Zinc Deficiency, Mother and Child Malnutrition
Multi-Omic Profiling of a Zinc-Biofortified Maize Intervention in Guatemalan Mothers and Children
A trial evaluating the systemic and ecological impact of zinc-biofortified maize consumption on cellular zinc status, inflammatory biomarkers, and gut microbiota composition in a cohort of Guatemalan mothers and children.
- Trial name
- NCT07585318
- Testing
- F3 Biofortified Maize, Conventional Maize
- Where
- Guatemala
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Institute of Nutrition of Central America and Panama
Zinc Deficiency, Growth; Stunting, Nutritional
The Efficacy of Zinc-biofortified Rice in Bangladeshi Children
To assess the efficacy of the zinc biofortified rice on plasma zinc concentrations in infants from a rural area of Bangladesh.
- Trial name
- ZARI (NCT03079583)
- Testing
- Intervention-group, Control-group
- Where
- 2 sites in Bangladesh, Switzerland
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Zinc Deficiency, Diarrhea
Impact of Preventive and Therapeutic Zinc Supplementation Programs Among Young Children
Zinc supplementation can either be provided in a lower daily dose to prevent zinc deficiency or in a higher dose for 10-14 days as part of the treatment of diarrhea.
- Conditions
- Zinc Deficiency, Diarrhea, Malaria
- Trial name
- NCT00944359
- Testing
- Surveillance control group
- Where
- Burkina Faso
- Volunteers
- 7,680 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Iron-deficiency, Anemia
Non-invasive Diagnostics of Iron Deficiency in Surgical Patients by Measuring Zinc Protoporphyrin-IX
In approx. 40% of the incidences anemia is caused by iron deficiency (= ID). In turn, preoperative iron-deficiency anemia (= IDA) is associated with an increase in morbidity and mortality as well as with the need for a blood…
- Conditions
- Iron-deficiency, Anemia, Iron Deficiency Anemia
- Trial name
- NCT03071497
- Testing
- Non-invasive analysis of Zinc protoporphyrin
- Where
- Germany
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Johann Wolfgang Goethe University Hospital
Iron Deficiency Anemia, Infectious Diseases
Efficacy Trial to Examine Efficacy of Multimicronutrient Home Supplementation in Infants
The objective of the program is to examine the efficacy of 6 month home micronutrient supplementation in Bedouin and Jewish children on improvements in nutritional status including measures of iron, ferritin, zinc and folic acid…
- Conditions
- Iron Deficiency Anemia, Infectious Diseases, Undernutrition
- Trial name
- NCT00276198
- Testing
- Sprinkles, Ferripel-3, Vitamins A&D drops
- Where
- Israel
- Volunteers
- 771 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Zinc Deficiency
Efficacy of Zn Biofortified Wheat in Improving Zn Status in Indian School Children With Low Zn Status
The objective of this research is to test the efficacy of Zn biofortified wheat in increasing Zn status in Indian school children aged 6-12 y via a 6 month randomized controlled trial.
- Trial name
- NCT02241330
- Testing
- Biofortified wheat, Fortification, Control
- Where
- India
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Fractional Absorption of Zinc (Focus of the Study)
Zinc Absorption From Fortified Water
A water purifying system, called LifeStrawFamily (LSF), able to fortify water with zinc to a concentration of 4 mg/l has been developed.
- Trial name
- NCT01636583
- Testing
- LSF water without meal, LSF water and inhibitory meal, Fortified inhibitory meal with water
- Where
- Switzerland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Zinc Deficiency
Impact of Targeted Zinc Fortification Programs on Plasma Zinc Concentration
The purpose of the study is to evaluate the use of plasma zinc concentration for assessing the impact of targeted zinc fortification programs.
- Trial name
- NCT00944398
- Testing
- Zinc fortified food, Zinc supplement, Non-fortified food
- Where
- Senegal
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Zinc Deficiency
Zinc and the Synthesis of Zinc Binding Proteins (Protocol B)
The specific aim of this protocol is to examine differential expression of specific mRNAs and proteins that occur when the dietary intake of zinc is acutely reduced below the dietary requirement for a period of ten days.
- Trial name
- NCT01221129
- Testing
- Acclimation, Dietary zinc depletion, Dietary zinc repletion
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Florida
Zinc Deficiency
A Novel Bio-marker of Zinc Status
Zinc deficiency is a widespread public health problem in developing countries. The true prevalence of this condition remains uncertain because of lack of a specific, sensitive and reliable biomarker for assessment of human zinc…
- Trial name
- NCT01062347
- Testing
- Zinc
- Where
- Bangladesh
- Volunteers
- healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Vitamin A Deficiency, Iron Deficiency
An Efficacy Trial of Iron, Zinc and Vitamin A Fortified Rice in Children in Satun, Thailand
Iron, zinc and vitamin A deficiencies are particularly common among children and young women in the developing countries of South and Southeast Asia resulting in important adverse health effects.
- Conditions
- Vitamin A Deficiency, Iron Deficiency, Zinc Deficiency
- Trial name
- NCT01061307
- Testing
- fortified extruded rice
- Where
- 2 sites in Switzerland, Thailand
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Zinc Deficiency, Inflammation
Effects of Daily Beef Intake, as a Component of a Heart-Healthy Diet on Cellular Zinc
The objective of the current study is to test the overarching hypothesis that the beef nutritive matrix is uniquely suited to direct dietary zinc to cellular compartments for improved metabolic function, leading to a greater…
- Conditions
- Zinc Deficiency, Inflammation, Metabolic Diseases, Vascular Diseases
- Trial name
- NCT05236374
- Testing
- Beef protein
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Hearing Loss, Noise-Induced, Tinnitus, Noise Induced
Improvement of Tinnitus After Oral Zinc on Patients With Noise-induced Hearing Loss
Twenty patients with tinnitus and a typical noise-induced hearing loss (NIHL) audiogram were included. Each subject underwent an otoscopic examination, distortion product otoacoustic emissions, tinnitus-match testing, Tinnitus…
- Conditions
- Hearing Loss, Noise-Induced, Tinnitus, Noise Induced, Zinc Deficiency
- Trial name
- NCT02951715
- Testing
- zinc gluconate
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
HIV Infections
Evaluating the Safety and Pharmacokinetics of PC-1005 Administered Rectally to HIV-1 Seronegative Adults
The purpose of this study is to evaluate the safety and pharmacokinetics of PC-1005 gel when used as a rectal microbicide in HIV-uninfected men and women (cis or transgender) with a history of consensual receptive anal…
- Trial name
- NCT03408899
- Testing
- PC-1005 gel
- Where
- 2 sites in United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Environmental Enteric Dysfunction, Zinc Deficiency
Effects of EED on Zn Absorption and Retention in Children From a MNP
The overall objective is to determine the impact of EED on total daily zinc absorption of young Bangladeshi children (18-24 months of age) in an austere setting with high rates of diarrhea, stunting, and micro-nutrient…
- Trial name
- ZEED2 (NCT02758444)
- Testing
- Micronutrient Powder (MNP) + 15 mg Zn, MNP + 10 mg Zn, MNP + 5 mg Zn
- Where
- 2 sites in United States, Bangladesh
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver