Clinical trials: Zoster; Herpes
Herpes Zoster
Efficacy and Safety of Foscarnet Sodium and Sodium Chloride Injection in Patients With Herpes Zoster
The purpose of this study is to evaluate the efficacy and safety of Foscarnet Sodium and Sodium Chloride Injection in patients with herpes zoster, and observe incidence of Postherpetic neuralgia
- Trial name
- Focus-101 (NCT02151240)
- Testing
- Foscarnet Sodium, Acyclovir
- Where
- China
- Volunteers
- 94 people
- Sponsor
- Cttq
Herpes Zoster, Pneumococcal Infection
ZOSTAVAX™ Administered Concomitantly With PNEUMOVAX™ 23 (V211-012)(COMPLETED)
The purpose of this study is to determine whether Zoster Vaccine Live and Pneumococcal Vaccine, polyvalent are as well tolerated and immunogenic when the vaccines are given together (in different body sites), as when they are…
- Trial name
- NCT00535730
- Testing
- Zoster Vaccine, Live, (Oka-Merck), ZOSTAVAX™, Pneumococcal Vaccine, Polyvalent (23-valent), PNEUMOVAX™ 23
- Volunteers
- 473 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Dermatologic Complications, Pain
Scrambler Therapy in Treating Chronic Pain in Patients With Rash From Varicella Zoster Virus Infection
This pilot clinical trial studies how well scrambler therapy works treating chronic pain in patients with rash from varicella zoster virus infection.
- Conditions
- Dermatologic Complications, Pain, Viral Infection
- Trial name
- NCT01347736
- Testing
- scrambler therapy, questionnaire administration, dermatologic complications management/prevention
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Mayo Clinic
Immunosenescence, Shingles
Vitamin D Supplementation And Varicella Zoster Virus Vaccine Responsiveness In Older Long-Term Care Residents
This is an ancillary study to a randomized controlled trial of high dose vitamin D in older long-term care residents (NCT01102374).
- Trial name
- NCT01262300
- Testing
- Varicella Zoster Virus Vaccine (Zostavax)
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Colorado, Denver
Varicella
Study of Two Formulations of GSK Biologicals' Varicella Vaccine
The aim of this study is to evaluate a modified formulation of GSK Biologicals' live attenuated varicella vaccine. In vivo pre-clinical data show this change has no negative impact on vaccine safety.
- Trial name
- NCT00568334
- Testing
- Varilrix (inactivated varicella vaccine)
- Where
- 13 sites in Czechia, Hungary
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Herpes Zoster
A Study to Assess Frailty of Subjects During ZOSTER-006 and ZOSTER-022
As part of the ZOSTER-006 and ZOSTER-022 pivotal trials of the HZ/su vaccine, all study participants completed quality of life (QoL) questionnaires.
- Trial name
- NCT03563183
- Testing
- Encoding of data collected in Zoster 006 and Zoster 022 studies
- Where
- 169 sites in United States, Australia and 16 more
- Volunteers
- 26,976 people
- Sponsor
- GlaxoSmithKline
Midpoint Transverse Process to Pleura Block, Erector Spinae Plane Block
Midpoint Transverse Process to Pleura (MTP) Block vs Erector Spinae Plane (ESP) Block for Acute Herpes Zoster (HZ) Pain
The aim of this study is to compare the analgesic efficacy and safety of ultrasound-guided midpoint transverse process block versus ultrasound-guided erector spinae plane block in patients suffering from thoracic herpes zoster…
- Conditions
- Midpoint Transverse Process to Pleura Block, Erector Spinae Plane Block, Acute Herpes Zoster, Pain
- Trial name
- NCT07732556
- Testing
- Midpoint transverse process to pleura block, Erector spinae plane block
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Varicella Zoster Virus Infection, Herpes Zoster
Clinical Trial to Evaluate EuHZV in Healthy Adults Aged 50 to 69 Years
Phase 1 clinical trial to evaluate the safety of HZV-1 and HZV-2 vaccines in healthy adults aged 50 to 69 years who have voluntarily given written consent to participate in this study.
- Trial name
- NCT06409494
- Testing
- EuHZV, Shingrix
- Where
- South Korea
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- EuBiologics Co.,Ltd
Neuralgia, Shingles
Dose-Finding Study of REN-1654 in Patients With Post-Herpetic Neuralgia
The purpose of this study is to gain initial safety and efficacy data on the experimental agent REN-1654 in patients with painful post-herpetic neuralgia (PHN).
- Conditions
- Neuralgia, Shingles, Peripheral Nervous System Disease
- Trial name
- NCT00099528
- Testing
- REN-1654
- Where
- 16 sites in United States
- Volunteers
- 90 people
- Sponsor
- Renovis
Post-Herpetic Neuralgia, Acute Herpes Zoster
Evolution of Pain From Herpes Zoster
Evolution of pain and neural injury will be evaluated at 2 years or longer after the onset of AHZ by multiple measures. Assessments at 2 years or longer will be compared to those collected during the first 6 months after HZ in…
- Trial name
- NCT00305357
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, San Francisco
Zoster; Herpes
Zoster Vaccine to Enhance Protection Against Zoster in Solid-organ Transplantation
Shingles is caused by the same virus that causes chickenpox. After someone has chickenpox, the virus stays in the body and can become active again later in life. This is called shingles.
- Trial name
- ZEST (NCT07443709)
- Testing
- Booster dose of the recombinant zoster vaccine (RZV, Shingrix®)
- Where
- Switzerland
- Volunteers
- 75 people
- Sponsor
- Oriol Manuel
Acute Herpes Zoster
Efficacy and Safety of Fire Needle Therapy Combined With Cortex Phellodendri Compound Fluid Wet Compress for Acute Herpes Zoster: a Randomized Controlled Trial.
Herpes zoster (HZ) results from a reactivation of varicella-zoster virus (VZV), which causes primary infection leading to chickenpox and remains latent in the ganglia.
- Trial name
- NCT06985589
- Testing
- Fire needle, Cortex Phellodendri compound fluid wet compress, basic treatment
- Where
- China
- Volunteers
- 32 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Varicella
Evaluate the Safety and Immunogenicity After MG1111(BARICELA Inj.) as 2nd Vaccination in 4 ~ 6 Year Old Healthy Children With a History of 1st Varicella Vaccination
Primary objective is to assess the safety of MG1111 until Day 42 using as 2nd vaccination Secondary objective to assess the immunogenicity and safety of MG1111 using as 2nd vaccination
- Trial name
- NCT05422508
- Testing
- MG1111 (BARICELA), VARIVAX, Suduvax
- Where
- South Korea
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Green Cross Corporation
Postherpetic Neuralgia
A Study to Determine if an Investigational Pain Medicine Provides Relief of Chronic Pain After a Shingles Outbreak
The purpose of this study is to determine whether T-62 is effective in providing relief of pain that can occur after an individual experiences a shingles outbreak, which is an infection in adults caused by the same virus that…
- Trial name
- NCT00506610
- Testing
- T-62
- Where
- 8 sites in United States
- Sponsor
- Pfizer
Persistent Corneal Epithelial Defects
Efficacy and Safety Study of Nexagon for Persistent Corneal Epithelial Defects
The purpose of this study is to evaluate the efficacy and safety of Nexagon® in subjects with persistent corneal epithelial defects (PED) resulting from corneal epithelial debridement during diabetic vitrectomy surgery, HSV…
- Trial name
- NTX-PED-001 (NCT01165450)
- Testing
- Nexagon, Vehicle only
- Volunteers
- 2 people
- Sponsor
- University of California, San Francisco
Varicella
The Evaluation of Immunogenicity and Safety of NBP608 in Healthy Children 12 Months to 12 Years of Age
This study evaluates the immunogenicity and safety of three different potencies of NBP608 and Varivax which are indicated for active immunization for the prevention of varicella.
- Trial name
- NCT03114982
- Testing
- NBP608, Varivax
- Where
- Philippines
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- SK Chemicals Co., Ltd.
Pain, Neuropathy;Peripheral
Morphological and Metabolic Changes of Dorsal Root Ganglion and Sympathetic Ganglion in Patients With Postherpetic Neuralgia on MRI
Object: Postherpetic neuralgia (PHN) is pain that persists for 1-3 months after herpes zoster onset. It is the most common complication of herpes zoster and occurs in 15-40% of patients with herpes zoster.
- Trial name
- NCT04880408
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Huazhong University of Science and Technology
Zoster Without Complications
Regional Anesthesia to Relief Zoster Pain
Pain in Herpes is a serious issue for patients. at the acute phase it is a moderate to severe pain . 30% patients will develop a post herpetic neuralgia this percentage up to 70 % after 60 years old.
- Trial name
- NCT04133142
- Testing
- peripheral nerve block, inter fascial nerve block
- Where
- Vietnam
- Sponsor
- Vinmec Healthcare System
Erysipelas, Impetigo
Tele-dermatology of Skin Cancer in a Cohort of Local Health Authority Employees in the Province of Bergamo
The purpose of this study is to demonstrate the validity and utility of a tele-dermatology system in the midterm periodic screening of non-widespread skin lesions of recent onset or for which a specialized early classification is…
- Conditions
- Erysipelas, Impetigo, Herpes Zoster, Molluscum Contagiosum
- Trial name
- NCT02902822
- Testing
- Screening, Tele-dermatology
- Where
- Italy
- Volunteers
- 461 people
- Sponsor
- Centro Studi Gised
Herpes Zoster, mRNA Vaccine
Study to Evaluate the Safety and Immunogenicity of a Lyophilized Herpes Zoster Virus mRNA Vaccine
This clinical trial included two parts, Part A and Part B. The goal of Part A is to evaluate the safety and preliminary immunogenicity of the lyophilized herpes zoster virus mRNA vaccine (HZ mRNA vaccine) in healthy populations…
- Trial name
- NCT07400003
- Testing
- Low-dose experimental vaccine, High-dose experimental vaccine, Active-controlled vaccine A
- Where
- China
- Volunteers
- 519 people, healthy volunteers welcome
- Sponsor
- Sinovac Biotech Co., Ltd