Clinical trials: acne
Acne Vulgaris
Study of Efficacy and Safety of CJM112 in Patients With Moderate to Severe Inflammatory Acne
The study was designed primarily to assess preliminary efficacy and safety of CJM112 in patients with moderate to severe inflammatory acne and to determine if CJM112 has an adequate clinical profile for further clinical…
- Trial name
- NCT02998671
- Testing
- CJM112
- Where
- 10 sites in United States, Germany and 1 more
- Volunteers
- 52 people
- Sponsor
- Novartis Pharmaceuticals
Acne
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Participants With Mild Acne
The purpose of the VBE00009 study is to evaluate the safety, efficacy and immunogenicity of 2 administrations of the Acne mRNA vaccine candidate at single dose level in participants aged 18 to 45 years with mild acne.
- Trial name
- NCT07013747
- Testing
- Acne mRNA vaccine
- Where
- 4 sites in United States
- Volunteers
- 228 people
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Acne
A Study to Evaluate Safety of ASC40 Tablets in Patients With Moderate to Severe Acne Vulgaris
This is a multicenter, open-label study designed to determine the long-term safety of ASC40 (Denifanstat) tablets in patients with moderate to severe acne vulgaris enrolled in the ASC40-303 Phase III study.
- Trial name
- NCT06248008
- Testing
- ASC40
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Ascletis Pharmaceuticals Co., Ltd.
Acne, Acne Scars - Mixed Atrophic and Hypertrophic
AVAVA MIRIA General Use
A general protocol to treat a variety of dermatologic conditions and collect patient feedback. Primary outcome is the collection and analysis of patient questionnaires related to the overall experience of the device treatment.
- Conditions
- Acne, Acne Scars - Mixed Atrophic and Hypertrophic, Scars, Wrinkle
- Trial name
- NCT06868615
- Testing
- AVAVA
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- AVAVA, Inc.
Acne Scars - Atrophic
Comparative Study of The Efficacy and Safety of Subcision Combined With Injection of Exosomes Versus Subcision Alone in Treatment of Atrophic Post- Acne Scars.
This split-face comparative prospective study was carried out on 20 patients presenting with atrophic post-acne scars. All participants were subjected to full history taking, general and dermatological examination, photographing…
- Trial name
- NCT07906509
- Testing
- Subcision plus exosome injection, Subcision
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Tanta University
Acne Vulgaris
Multiple Arm Study of Sebacia Microparticles in the Treatment of Acne Vulgaris
Prospective, multicenter study with multiple arms to examine the safety and effectiveness of the Sebacia Acne Treatment System for the treatment of acne vulgaris.
- Trial name
- NCT02219074
- Testing
- Sebacia microparticle and laser treatment, Vehicle and laser treatment
- Where
- 2 sites in Poland
- Volunteers
- 350 people
- Sponsor
- Sebacia, Inc.
Acne Vulgaris
Afamelanotide in Patients Suffering With Acne Vulgaris
This study aims to evaluate the effect of afamelanotide on the facial inflammatory acne-related lesions in patients with mild to moderate acne vulgaris, including tolerability of afamelanotide by patients with moderate acne…
- Trial name
- NCT04943159
- Testing
- Afamelanotide
- Volunteers
- 3 people
- Sponsor
- Clinuvel Pharmaceuticals Limited
Acne, Atrophic Scar
Comparison of Picosecond Lasers vs. Ablative Fractional Er:YAG Lasers in Treating Atrophic Scar
The 1064-nm Nd:YAG picosecond lasers using fractional micro-lens array (P-MLA) was a promising therapy for skin resurfacing. However, no studies have compared P-MLA with ablative fractional 2940-nm Er:YAG lasers (AF-Er) in…
- Trial name
- NCT05686603
- Testing
- a fractional 1064-nm neodymium-doped yttrium aluminum garnet (Nd:YAG) picosecond laser with MLA handpiece, a ablative fractional 2940-nm Er:YAG laser
- Where
- China
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Acne Vulgaris
Weekly Isotretinoin Therapy Study
In current Dermatology practice, options for moderate acne vulgaris remain limited. The mainstay of treatment for moderate acne remains long courses of oral antibiotics despite emerging antibiotic resistance.
- Trial name
- WIT (NCT04594759)
- Testing
- Isotretinoin
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Medical University of South Carolina
Acne
Clinical End Point Study of Generic Adapalene and Benzoyl Peroxide Gel Versus Epiduo® Forte Gel in Treatment of Acne Vulgaris
A Randomized, Double-Blind, Placebo-Controlled, Parallel-Design, Multiple-Site Clinical Study to Evaluate the Therapeutic Equivalence and Safety of adapalene and benzoyl peroxide gel, 0.3%/2.5% (Actavis Laboratories UT, Inc.) to…
- Trial name
- NCT02651220
- Testing
- Epiduo® Forte Gel, Adapalene and Benzoyl Peroxide Gel
- Where
- 20 sites in United States, Belize
- Volunteers
- 1,001 people, healthy volunteers welcome
- Sponsor
- Actavis Inc.
Acne Vulgaris
A Study to Evaluate Efficacy and Safety of HB0043 in Aadult Patients With Moderate to Severe Acne Vulgaris.
The purpose of this study is to assess efficacy safety and tolerability of HB0043 in adult patients with moderate to severe AV.
- Trial name
- NCT07449156
- Testing
- HB0043
- Where
- China
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Shanghai Huaota Biopharmaceutical Co., Ltd.
Hidradenitis Suppurativa, Acne Inversa
A Study to Evaluate the Efficacy, Safety and Tolerability of Bermekimab in Patients With Hidradenitis Suppurativa
This study further evaluates the efficacy of bermekimab in treating moderate to severe hidradenitis suppurativa in adults. 1/3 of patients will receive weekly injections of bermekimab, 1/3 will receive alternating every other…
- Conditions
- Hidradenitis Suppurativa, Acne Inversa, Suppurative Hidradenitis
- Trial name
- NCT04019041
- Testing
- bermekimab
- Where
- 33 sites in United States
- Volunteers
- 153 people
- Sponsor
- Janssen Research & Development, LLC
Acne Vulgaris
Dalacin-T Gel Post Approval Study
To investigate, in a comparison vs. Acuatim cream (nadifloxacin cream), the efficacy and safety of Dalacin T Gel (clindamycin phosphate gel) as a therapeutic medication for acne vulgaris in acne vulgaris patients, including…
- Trial name
- NCT00219570
- Testing
- clindamycin, nadifloxacin
- Volunteers
- 134 people
- Sponsor
- Pfizer
Acne Vulgaris
Phase IV Study to Gather More Information About the Safety of ACZONE Gel, 5% in Treating Subjects With Acne Who Have G6PD Deficiency
The purpose of this study is to gather more information about the safety of ACZONE Gel, 5% in treating subjects with acne who have certain blood disorders.
- Trial name
- NCT00243542
- Testing
- ACZONE Gel, 5%, Vehicle
- Where
- 29 sites in United States
- Volunteers
- 64 people
- Sponsor
- Allergan
Acne Vulgaris
Impact of Isotretinoin in Different Doses on Quality of Life
The Cardiff Acne Disability Index is a short five-item questionnaire derived from the longer Acne Disability Index.It is designed for use in teenagers and young adults with acne.
- Trial name
- NCT05316675
- Testing
- Isotretinoin
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Acne Vulgaris
A Dose-Ranging Study Evaluating the Safety and Efficacy of IDP-107 in Patients With Acne Vulgaris
The purpose of this study is to evaluate the safety and efficacy of IDP-107 versus placebo in treating patients with acne vulgaris.
- Trial name
- NCT01194375
- Testing
- Low Strength IDP-107, High Strength IDP-107
- Where
- 20 sites in United States, Canada
- Volunteers
- 180 people
- Sponsor
- Dow Pharmaceutical Sciences
Acne Vulgaris
CD5789 (Trifarotene) Long Term Safety Study on Acne Vulgaris
Multi-center, open-label, non-comparative safety and efficacy study with 52 Weeks of treatment on the face and trunk for acne vulgaris.
- Trial name
- NCT02189629
- Testing
- CD5789 (trifarotene)
- Where
- 32 sites in United States, Czechia and 2 more
- Volunteers
- 453 people
- Sponsor
- Galderma R&D
Wrinkles, Acne Scars
Fractional Ablative Radiofrequency for the Treatment of Acne Scars and Wrinkles
To assess the safety and efficacy of the Pixel RF (fractional radio frequency) module in the treatment of acne scars and wrinkles.
- Trial name
- NCT01645345
- Testing
- Alma Lasers Accent RF Pixel handpiece
- Where
- 3 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Alma Lasers Inc.
Acne Vulgaris
Efficacy and Safety of a Preparation Containing an Antibiotic and Anti-Inflammatory Agent in Acne Vulgaris
The concept behind our study was to combine an effect of antibiotic and anti-inflammatory agents for a more efficient acne therapy directed at the factors involved in the pathophysiology of the disease.
- Trial name
- NCT00361322
- Testing
- clindamycin phosphate, salicylic acid
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Hadassah Medical Organization
Acne Vulgaris, Medical Education
AI-Generated Acne Vulgaris Learning Material Study
This comparative educational intervention study evaluated the educational effectiveness of artificial intelligence-generated patient information material on acne vulgaris among early-year medical students.
- Trial name
- NCT07652112
- Testing
- Artificial Intelligence-Generated Acne Vulgaris Educational Material, Turkish Dermatology Association Acne Vulgaris Educational Material
- Where
- Turkey (Türkiye)
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Hasan Durmuş
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