Clinical trials: asthma
Asthma
Characteristics of Pts Initiating Spiriva Respimat in Asthma
This study is a cross-sectional, non-interventional study based on existing data (NISed).
- Trial name
- NCT03692676
- Testing
- Spiriva Respimat
- Where
- Germany
- Volunteers
- 116,133 people
- Sponsor
- Boehringer Ingelheim
Asthma
Improvement of FeNO and FEF25-75 After Inhaled Corticosteroid Treatment of Asthma
Abnormal lung function and high exhaled nitric oxide (FeNO) have been reported in asymptomatic patients with asthma. The investigators aimed to assess whether FeNO and FEF25-75 improve concurrently after treatment with inhaled…
- Trial name
- NCT01340118
- Testing
- Budesonide
- Where
- South Korea
- Volunteers
- 93 people
- Sponsor
- Chungbuk National University
Asthma, Allergic Rhinitis
Influence of Probiotics on Atopy With Focus on Respiratory Allergic Diseases- Follow-up to 7 Years
The investigators had conducted an initial double-blind, placebo-controlled clinical trial (NCT00318695) to study the effects of probiotic supplementation from birth to 6 months of age in the incidence of atopic diseases at 2…
- Trial name
- NCT00826189
- Where
- Singapore
- Volunteers
- 253 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Asthma
Measuring the Effect of Dupilumab Treatment on Mucociliary Clearance (MCC) in Subjects With Moderate to Severe Asthma
Single center, randomized, placebo- controlled study to assess change in mucociliary clearance of moderate to severe asthma patients after treatment with dupilumab or placebo.
- Trial name
- NCT04743791
- Testing
- Dupilumab
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Sally E. Wenzel MD
Asthma
Teen Asthma Project
Aims of this study are: 1. To determine the feasibility of implementing the intervention using a peer-assisted asthma day camp for adolescents with asthma. 2.
- Trial name
- TAP (NCT01161225)
- Testing
- Peer-assisted asthma self-management program, Adult-led asthma self-management program
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- University of Rochester
Asthma
School-based Approaches to Help Pre-teens Manage Asthma
This random trial will deploy 2 interventions and a control group with eleven and twelve year old, low income, African American students in middle schools in Detroit, MI.
- Trial name
- DMSP (NCT00217776)
- Testing
- Open Airways Educational Intervention, Peer Asthma Action Educational Intervention
- Volunteers
- 1,292 people
- Sponsor
- University of Michigan
Asthma
Effect of OMT on Asthma Symptoms in Southwest Virginia
There is a high prevalence of asthma in southwest Virginia and there are multiple osteopathic manipulative techniques (OMT) which are thought to improve lung function.
- Trial name
- NCT00545376
- Testing
- Osteopathic Manipulative Treatment - in clinic, Osteopathic Manipulative Treatment - at home, Education to physicians
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Edward Via Virginia College of Osteopathic Medicine
Atrial Fibrillation, Coronary Heart Disease
EMPOWER-1: A Multi-site Clinical Cohort Research Study to Reduce Health Inequality
Health inequality and genetic disparity are a significant issue in the United Kingdom (UK). This study focuses on diseases that are associated with significant morbidity and mortality in the UK, and specifically examines the…
- Conditions
- Atrial Fibrillation, Coronary Heart Disease, Cardiovascular Diseases, Heart Failure
- Trial name
- EMPOWER (NCT03987633)
- Where
- United Kingdom
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- Future Genetics Limited
Asthma
Study in Mild Asthmatic Patients
The purpose of this study is to determine the safety and usefulness of GSK2190915 in asthmatic patients who develop asthma symptoms following being challenged.
- Trial name
- NCT00748306
- Testing
- GSK2190915 - 100mcg
- Where
- 4 sites in Netherlands, United Kingdom
- Volunteers
- 19 people
- Sponsor
- GlaxoSmithKline
Asthma
Repeat Dose GW685698X With Magnesium Stearate, Excipient Bridging Study, In Healthy Volunteers
GW685698X is a novel glucocorticoid receptor agonist that is being developed as an orally inhaled treatment for asthma. In previous studies inhaled GW685698X was administered as a dry powder containing either lactose alone or…
- Trial name
- NCT00522678
- Testing
- GW685698X
- Where
- Australia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Asthma
The Study of Soy Isoflavones in Asthma
The trial is designed to study the effects of soy supplements on asthma control.
- Trial name
- SOYA (NCT01052116)
- Testing
- Soy isoflavone supplement
- Where
- 18 sites in United States
- Volunteers
- 386 people
- Sponsor
- American Lung Association Asthma Clinical Research Centers
Asthma
Airway Remodeling During Mepolizumab Treatment
Chronic airway changes, such as smooth muscle hypertrophy/hyperplasia, reticular basement membrane (RBM) thickening, goblet cells hyperplasia characterize severe asthma.
- Trial name
- REMOMEPO (NCT03797404)
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Asthma
Patient Empowered Strategy to Reduce Asthma Morbidity in Highly Impacted Populations; PeRson EmPowered Asthma RElief
Asthma imposes a significant burden in the US in terms of morbidity, costs to society, individual suffering, loss of productivity and mortality.
- Trial name
- PREPARE (NCT02995733)
- Testing
- PARTICS using QVAR
- Where
- 20 sites in United States, Puerto Rico
- Volunteers
- 1,220 people
- Sponsor
- Brigham and Women's Hospital
Asthma, Chronic Obstructive Pulmonary Disease
A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Dose in Healthy Volunteers, Repeat Doses in Asthmatic Patients and of Single Dose in COPD Patients of CHF6366
CHF6366 is a novel bifunctional compound displaying both muscarinic receptor antagonist and β2-adrenergic receptor agonist properties (MABA), with the potential to deliver optimal bronchodilation after inhalation dosing via two…
- Trial name
- NCT03378648
- Testing
- CHF6366, umeclidinium bromide and vilanterol trifenatate
- Where
- United Kingdom
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Chiesi Farmaceutici S.p.A.
Asthma
This is a 6-month Observational Study. Patients Included Will be Those Referred With a Possible Diagnosis or an Established Diagnosis of Asthma. It Will Look at the Association of the Asthma Microbiome and Disease Characteristics, Severity and Treatment Response.
The goal of this observational study is to investigate the role of the lung microbiome in patients with asthma and how it may influence the response to asthma specific treatments.
- Trial name
- NCT06028204
- Testing
- Biologic Agent
- Volunteers
- 60 people
- Sponsor
- Royal College of Surgeons, Ireland
Asthma
Helping Chicago's Westside Adults Breathe and Thrive
Adults with asthma living in Chicago's West and Southwest side who completed the home-based Community Health Worker (CHW) intervention called Helping Chicago's Westside Adults Breathe and Thrive (HCWABT I) after October 2015 were…
- Trial name
- HCWABT (NCT03489655)
- Testing
- Maintenance Phase Intervention
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- Sinai Health System
Sinusitis, Chronic, Asthma
Aggravated Airway Inflammation: Research on Genomics and Optimal Operative Treatment (AirGOs Operative)
This randomized study compares operative techniques in chronic rhinosinusitis with polyposis (CRSwNP) surgery. It aims to evaluate outcomes in asthma and CRSwNP, safety and costs.
- Conditions
- Sinusitis, Chronic, Asthma, Nasal Polyps, Aspirin Sensitivity
- Trial name
- NCT03704415
- Testing
- Extended endoscopic sinus surgery, Limited endoscopic sinus surgery
- Where
- 3 sites in Finland, Netherlands
- Volunteers
- 97 people
- Sponsor
- Helsinki University Central Hospital
Asthma, Lung Diseases
Community Intervention for Minority Children With Asthma
To test the effectiveness of school-based asthma education interventions, community-based asthma health workers' programs and the combination of these on asthmatic children.
- Trial name
- NCT00005715
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Allergic Asthma
House Dust Mite Induced Inflammasome Activation on Corticosteroid Resistance
In this project, PBMCs will be isolated from HDM allergic and non allergic patient and then stimulated with HDM crude extract. The expression of inflammasome and the correlation of inflammasome activation and steroid resistance…
- Trial name
- NCT03307278
- Testing
- House dust mite
- Volunteers
- healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Asthma, Allergies
Cohort Study of the Patterns of Microvesicles in the Serum of Participants With Atopic and Non-atopic Asthma
The purpose of this study is to determine if a simple blood test can help in disease management, particularly asthma. This will be researched by looking at certain features of the blood and to compare asthmatics without allergies…
- Trial name
- NCT00700726
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Ohio State University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.