Clinical trials: asthma
Stroke (CVA) or TIA, Diabetes
Risk Factors, Costs, and Impacts of ED Boarding
The goal of this observational study is to learn about the risk factors, costs, and operational impacts of emergency department boarding (patients admitted to the hospital but remaining in the emergency department awaiting…
- Conditions
- Stroke (CVA) or TIA, Diabetes, Asthma (Diagnosis), COPD (Chronic Obstructive Pulmonary Disease)
- Trial name
- NCT07532564
- Where
- United States
- Volunteers
- 30,486 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Asthmatic
Influenza Vaccine Feasibility Study in Children With Persistent Asthma
This study is designed to note whether a larger safety study using quadrivalent live attenuated influenza vaccine (LAIV4) versus quadrivalent inactivated influenza vaccine (IIV4)(FLUARIX®), would be feasible in children with…
- Trial name
- NCT02967393
- Testing
- ccIIV4, IIV4
- Where
- 4 sites in United States
- Volunteers
- 40 people
- Sponsor
- Vanderbilt University Medical Center
Asthma
A Study to Evaluate the Effect of of Albuterol Sulfate Inhalation Aerosol, eq 90 mcg Base (Sun Pharmaceuticals Industries Limited)
To Evaluate the Pharmacodynamic Equivalence of Albuterol Sulfate Inhalation Aerosol, eq 90 mcg base (Sun Pharmaceuticals Industries Limited) to PROAIR® HFA (albuterol sulfate) Inhalation Aerosol, eq 90 mcg base (Teva Respiratory…
- Trial name
- NCT03528577
- Testing
- Zero-dose, 90 mcg of PROAIR® HFA, 180 mcg of 90 mcg of PROAIR® HFA
- Where
- 8 sites in United States
- Volunteers
- 128 people
- Sponsor
- Sun Pharmaceutical Industries Limited
Asthma
Study of Asthma Phenotypes and Pharmacogenomic Interactions by Race-Ethnicity (SAPPHIRE)
Inhaled corticosteroids (ICS) are considered first-line treatment for persistent asthma, yet little is known about the genetic factors that influence response to this therapy.
- Trial name
- SAPPHIRE (NCT01142947)
- Testing
- beclomethasone dipropionate
- Where
- United States
- Volunteers
- 362 people
- Sponsor
- Henry Ford Health System
Asthma
Investigation of the 24 Hour Forced Expiratory Flow in 1 Second (FEV1) Profile of a Single Dose of Indacaterol/Mometasone Delivered Via the TWISTHALER® Device in Adult Patients With Persistent Asthma
This study is designed to provide data about the 24 hours FEV1 profile, safety and tolerability of indacaterol/mometasone TWISTHALER device compared to placebo and using fluticasone/salmeterol as an active control.
- Trial name
- NCT00557440
- Testing
- fluticasone propionate/salmeterol, indacaterol maleate / mometasone furoate
- Where
- 6 sites in Belgium, Germany
- Volunteers
- 37 people
- Sponsor
- Novartis
Asthma
Efficacy and Safety of 2 Doses of Tiotropium Respimat® Compared to Placebo in Children With Severe Persistent Asthma
The overall purpose of the trial is to evaluate efficacy and safety of tiotropium inhalation solution (2.5 mcg and 5 mcg) delivered via Respimat® inhaler once daily in the evening over 12 weeks, compared to placebo, as add-on…
- Trial name
- NCT01634152
- Testing
- Tiotropium low dose mcg, Tiotropium high dose
- Where
- 94 sites in United States, Argentina and 15 more
- Volunteers
- 401 people
- Sponsor
- Boehringer Ingelheim
Asthma
Albuterol HFA MDI in Pediatric Participants With Asthma
The primary objective of this study is to evaluate the chronic-dose and efficacy of Albuterol-HFA-MDI relative to placebo in pediatric asthmatics.
- Trial name
- NCT00577655
- Testing
- Albuterol, Proventil® HFA
- Where
- 13 sites in United States
- Volunteers
- 103 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Persistent Asthma
Study of Safety of Foradil in Patients With Persistent Asthma
The purpose of this study was to assess whether the risk of serious asthma-related events (asthma-related hospitalizations, asthma related intubations, and asthma related deaths) in adolescents and adults (12 years of age and…
- Trial name
- NCT01845025
- Testing
- Formoterol 12 mcg, Fluticasone propionate 100 mcg, Fluticasone propionate 250 mcg
- Where
- 27 sites in United States
- Volunteers
- 827 people
- Sponsor
- Novartis Pharmaceuticals
Asthma
Vitamin D to Prevent Severe Asthma Exacerbations (Vit-D-Kids Asthma)
This study will determine whether vitamin D3 prevents severe asthma attacks in children who have a serum vitamin D (25(OH)D) level <30 ng/ml and who are being treated with inhaled corticosteroids for asthma.
- Trial name
- NCT02687815
- Testing
- vitamin D3 4000 IU
- Where
- 7 sites in United States
- Volunteers
- 192 people
- Sponsor
- Juan Celedon, MD
Asthma
A Study of Omalizumab (Xolair) in Subjects With Moderate to Severe Persistent Asthma (EXTRA)
This is a multicenter, randomized, double-blind, placebo-controlled study of the efficacy, safety, and tolerability of subcutaneously administered Xolair as add-on therapy for the treatment of subjects aged 12-75 years old…
- Trial name
- NCT00314574
- Testing
- omalizumab (Xolair), corticosteroids, long-acting beta-agonists
- Volunteers
- 850 people
- Sponsor
- Genentech, Inc.
Bronchial Asthma, Asthma
HFCWO in Hospitalized Asthmatic Children
To determine whether or not high frequency chest wall oscillation (in the form of the VestTM) is superior to regular asthma therapy in the management of children hospitalized with moderate to severe asthma.
- Conditions
- Bronchial Asthma, Asthma, Status Asthmaticus
- Trial name
- NCT00722020
- Testing
- VEST
- Where
- 2 sites in United States
- Volunteers
- 43 people
- Sponsor
- Hill-Rom
Respiratory System Agents, Anti-Asthmatic Agents
Study to Evaluate Safety and Efficacy of Benralizumab in Subjects With Hypereosinophilic Syndrome
Background: Eosinophils are white blood cells that help fight infections. High eosinophil levels can damage people s organs, causing hypereosinophilic syndrome (HES).
- Conditions
- Respiratory System Agents, Anti-Asthmatic Agents, Hematologic Diseases, Leukocyte Disorders
- Trial name
- HESIL5R (NCT02130882)
- Testing
- benralizumab
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Asthma, Genotype
Evaluate Pharmacokinetics and Safety of Slow Release DHEA
This is a study to look at pharmacokinetic levels of different doses of slow release DHEA in subjects with asthma.
- Trial name
- DHEA (NCT05623059)
- Testing
- Slow Release DHEA
- Where
- 2 sites in United States
- Volunteers
- 18 people
- Sponsor
- Indiana University
Bronchial Asthma
Clinical Assessment Of GW815SF Salmeterol/Fluticasone Propionate(HFA MDI) In Pediatric Patients With Bronchial Asthma -A Long Term (24-week) Study-
This study evaluates the long-term (24-week) safety and efficacy of GW815SF Salmeterol/fluticasone propionate(HFA MDI) 50/100mcg(administered as 2 inhalations of 25/50mcg) bid in pediatric patients with bronchial asthma.
- Trial name
- NCT00449046
- Testing
- GW815SF Salmeterol/Fluticasone propionate(HFA MDI)
- Where
- 3 sites in Japan
- Volunteers
- 40 people
- Sponsor
- GlaxoSmithKline
Asthma
Study Evaluating the Effects of IMA-638 on Allergen-Induced Airway Responses in Subjects With Mild Atopic Asthma
Primary purpose of the protocol is to determine if IMA-638 prevents a mild asthma attack by a subject with mild asthma inhaling an allergen.
- Trial name
- NCT00410280
- Testing
- IMA-638 is a biologic
- Where
- 4 sites in Canada
- Volunteers
- 30 people
- Sponsor
- Pfizer
Asthma
Results Of Patient Rated Asthma Control Test In Comparison To Diary Card Data
The majority of asthma patients are not well controlled, despite the availability of asthma medication that could effectively treat the disease.
- Trial name
- NCT00363480
- Testing
- Salmeterol/Fluticasone 50/250 mcg, Salbutamol 100 mcg, DISKUS™ powder inhalers
- Where
- 32 sites in Germany
- Volunteers
- 221 people
- Sponsor
- GlaxoSmithKline
Asthma
Single Dose Bronchodilatory Study in Asthma
Study to evaluate the bronchodilator effects of Zyflo CR in patients with chronic stable asthma.
- Trial name
- NCT01805687
- Testing
- Zileuton extended release
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Cornerstone Therapeutics Inc.
Asthma
Randomized Trial: Maternal Vitamin D Supplementation to Prevent Childhood Asthma (VDAART)
Vitamin D supplementation given to pregnant women will prevent asthma in their offspring and children.
- Trial name
- VDAART (NCT00920621)
- Testing
- Vitamin D 3 cholecalciferol, Vitamin D3
- Where
- 3 sites in United States
- Volunteers
- 876 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Asthma
Study of the Ease of Use and Correct Use of Placebo ELLIPTA® Inhaler in Subjects With Asthma
Asthma is a chronic disease of the lungs characterized by airway inflammation, bronchoconstriction and increased airway responsiveness.
- Trial name
- NCT02586506
- Testing
- Questionnaire
- Where
- 15 sites in United States
- Volunteers
- 259 people
- Sponsor
- GlaxoSmithKline
Atopic Asthma
A Double Masked, Placebo Controlled, Single Center, Randomized Clinical Trial to Assess the Safety and Efficacy of Subjects With Mild Asthma Induced by the Bronchial Allergen Challenge (BAC)
A Double Masked, Placebo Controlled, Single Center, Randomized Clinical Trial to Assess the Safety and Efficacy of ADX-629 in Subjects with Mild Asthma Induced by the Bronchial Allergen Challenge (BAC)
- Trial name
- NCT04728711
- Testing
- ADX-629
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- Aldeyra Therapeutics, Inc.
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