Clinical trials: asthma
Asthma
To Investigate the Effects of Altering the Time of Day of Dosing (Morning or Evening) With Fluticasone Furoate 100 Micrograms Once Daily Administered Via a Dry Powder Inhaler in Subjects With Asthma
This study will investigate the effects of altering the time of day of dosing (morning or evening) with Fluticasone Furoate 100 (FF 100) micrograms (mcg) once daily administered via a dry powder inhaler (DPI) in subjects with…
- Trial name
- NCT01808339
- Testing
- Fluticasone Furoate (FF)
- Where
- Australia
- Volunteers
- 28 people
- Sponsor
- GlaxoSmithKline
Asthma
Evaluation of the Effect of Levalbuterol on Allergen Induced Airway Inflammation In Subjects With Atopic Asthma
The most commonly used drug for immediate relief of symptoms of asthma is the blue puffer, albuterol or salbutamol (Ventolin). Racemic albuterol is a mixture of two forms of albuterol which are mirror images of each other i.e.
- Trial name
- NCT00320034
- Testing
- R-albuterol, S-albuterol
- Volunteers
- 15 people
- Sponsor
- Hamilton Health Sciences Corporation
Exercise Induced Asthma
Kt and Myofascial Release in Exc Asthma
Purpose of this study was to compare between the effects of kinesio tap and myofascial release of respiratory muscles on exercise induced asthma
- Trial name
- NCT05703334
- Testing
- Kinesio tap
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Cairo University
Asthma
Bronchial Thermoplasty in Severe Asthma With Frequent Exacerbations
The purpose of this study is to demonstrate the effectiveness of bronchial thermoplasty in a severe asthmatic population with frequent exacerbations. This will be a single center randomized and controlled study.
- Trial name
- THERMASCORT (NCT02464995)
- Testing
- Bronchial thermoplasty with the Alair System
- Where
- France
- Volunteers
- 34 people
- Sponsor
- University Hospital, Strasbourg, France
Asthma
Effect of Age and Device on Delivery of Fluticasone
To determine the effect of age and device on delivery of HFA-Fluticasone Propionate (FP) in children of different ages. Hypothesis -- passive inhalation in younger children through a valved holding chamber/mask (VHC) will reduce…
- Trial name
- NCT00308932
- Testing
- HFA FP MDI
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Florida
Asthma
Finding Correlations Between Asthma Exacerbation, Physiological Measurements and Environmental Factors
To identify asthma-related physiological changes observed by wearable devices in real-world conditions by monitor multiple sensing modalities (e.g., heart rate (HR), heart rate variability (HRV), activity level, spirometry…
- Trial name
- SCH Asthma (NCT04845932)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- North Carolina State University
Obesity, Asthma
Obesity-asthma Endophenotype and Diaphragm Mobility in Adolescence
Obesity and asthma share changes that may begin in the fetal development phase. The endophenotype obesity-asthma presents as main characteristic a pattern of inflammatory response different from the habitual Th2 profile of…
- Trial name
- NCT03029936
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Asthma
Safety, Tolerability and Pharmacokinetics of ASM-024 Administered to Healthy Subjects and Subjects With Moderate Asthma
The purpose of this study is to evaluate the safety and tolerability of the dry powder formulation of ASM-024 following single and multiple administration by inhalation of ascending doses in healthy subjects and subjects with…
- Trial name
- NCT01793298
- Testing
- ASM-024
- Where
- 2 sites in Canada
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Asmacure Ltée
Asthmatic
Lung Bioavailability and Total Systemic Exposure to Beclomethasone17MonoPropionate and Formoterol Across Two Strengths of NEXThaler Inhalation Powder
The study is aimed to assess the dose proportional total systemic exposure (when the administration is without the activated charcoal) to B17MP (active metabolite of BDP) and its lung bioavailability (when the administration is…
- Trial name
- NCT01738087
- Testing
- NEXThaler 100/6 mcg DPI, Flixotide Accuhaler 500 mcg, NEXThaler 200/6 mcg DPI
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Asthma
Combined Effects Of Diaphragm Strengthening And Accessory Muscles Stretchings In Asthma Patients
Asthma is a multifactorial and chronic inflammatory disease in older patients affecting many people worldwide with high cost of pharmacological treatment and physiotherapy interventions.
- Trial name
- NCT05915793
- Testing
- Diaphragm strengthening and accessory muscles stretchings, Diaphragm strengthening
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Tetraplegia, Asthma
Exhaled Breath Condensate Biomarkers of Inflammation in Individuals With Chronic Cervical Spinal Cord Injury
The purpose of this study is to obtain markers of airway inflammation from the exhaled breath condensate (the moisture in exhaled air) for comparison to blood based markers.
- Trial name
- NCT02235714
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Asthma, Allergy
Effects of Plant Stanols on Immune Function in Asthma Patients
Rationale: Plant stanols are well known for their effects on lowering intestinal cholesterol absorption ultimately resulting in 10-15% reduced serum LDL cholesterol concentrations in humans.
- Trial name
- NCT01715675
- Testing
- Plant stanol enriched soy-based yoghurt, Soy-based yoghurt without added plant stanols
- Where
- Netherlands
- Volunteers
- 61 people
- Sponsor
- Maastricht University Medical Center
Asthma
A Safety, Efficacy and Tolerability Study in Pediatric Subjects With Asthma
A Safety, Efficacy, and Tolerability Study of Daily Dosing with Levalbuterol Tartrate HFA MDI and Placebo in Subjects Aged Birth to <48 Months with Asthma.
- Trial name
- NCT00809757
- Testing
- Levalbuterol, Levalbuterol UDV TID
- Where
- 46 sites in United States
- Volunteers
- 197 people
- Sponsor
- Sumitomo Pharma America, Inc.
Asthma, Lung Diseases
Intervention to Improve Asthma Management/Prevention
To implement and evaluate a comprehensive asthma education and prevention program in all 54 public elementary schools in the predominantly minority Birmingham, Alabama school system.
- Trial name
- NCT00005734
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Asthma, Lung Function Decreased
Dietary Intake in Adults From the GA2LEN Folow-up Survey
The Nutrition Study of the GA2LEN Follow-Survey was designed to investigate the association between usual dietary intake and allergic and respiratory outcomes in adults across Europe.
- Conditions
- Asthma, Lung Function Decreased, Food Allergy, Allergic Sensitisation
- Trial name
- NCT03251157
- Testing
- Dietary intake of various nutrients, foods and biocompounds
- Where
- United States
- Volunteers
- 3,500 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Asthma
Efficacy and Safety of Fluticasone Propionate(FP)/ Salmeterol Xinafoate (SLM) Hydro Fluoro Alkane (HFA) Metered Dose Inhaler (MDI) in Pediatric Patients With Bronchial Asthma
This study is a multicenter, stratified, randomized, active control, double-blinded, parallel-group comparative study with an open-label extension period.
- Trial name
- NCT02113436
- Testing
- FP/ SLM HFA MDI 50/25 mcg, FP HFA MDI 50 mcg
- Where
- 69 sites in Japan
- Volunteers
- 300 people
- Sponsor
- GlaxoSmithKline
Asthma
Parent Mentor Asthma Study
Asthma disproportionately affects minorities, but few studies have evaluated interventions to improve asthma outcomes in minority children.The purpose of the study is to determine whether Parent Mentors (PMs) are more effective…
- Trial name
- PMA (NCT00812136)
- Testing
- Using Parent Mentors to Improve Asthma Care for Urban Minority Children
- Sponsor
- University of Texas Southwestern Medical Center
Asthma
Inhaled Steroids at Discharge After Emergency Department Visits for Children With Uncontrolled Asthma
Many children have asthma and this causes problems with their health. A lot of children with uncontrolled asthma use emergency departments for asthma care, and so this is an ideal place for an intervention for these children.
- Trial name
- NCT01881412
- Testing
- fluticasone, Standard Asthma Discharge Instructions
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- Rhode Island Hospital
Asthma
Exhaled Hydrogen Sulphide as a Biomarker of Airways Disease in Asthma
The purpose of this study will be to determine whether there is any role for measuring Hydrogen Sulphide (H2S) in the exhaled breath in terms of management of the patient with asthma.
- Trial name
- NCT02703467
- Where
- United Kingdom
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Asthma
Safety and Tolerability of Ciclesonide and Formoterol Fumarate Inhaled Once Daily in Patients With Asthma (18 to 75 y) (BY9010/M1-506)
The aim of the study is to compare the efficacy of two doses of a fixed combination of ciclesonide/formoterol fumarate versus ciclesonide alone versus formoterol fumarate alone in patients with asthma.
- Trial name
- NCT00314509
- Testing
- Ciclesonide/Formoterol Combination
- Where
- 26 sites in France, Germany and 2 more
- Volunteers
- 240 people
- Sponsor
- AstraZeneca
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