Clinical trials: i-PRF
Vital Pulp Treatment in Mature Permanent Teeth With Irreversible Pulpitis
Clinical and Radiographic Assessment of Nano-Bioactive Glass Combined With I-PRF Scaffold in Vital Pulp Treatments in Mandibular Molars With Closed Apices
Clinical, Radiographic and pain assessment of Vital pulp treatment in patients suffering from irreversible pulpitis in mature permanent molars.
- Trial name
- I-PRF (NCT05876520)
- Testing
- Total pulpotomy with I-prf mixed with Nano-bioactive glass
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Impacted Third Molar Tooth
Comparison of the Efficacy of I-Prf Impregnated Collagen and L-Prf on Healing After Impacted Third Molar Surgery
Impacted third molar extraction is a very common surgical intervention. Post-procedure pain causes various post-operative changes such as edema and trismus.
- Trial name
- NCT05563519
- Testing
- I-PRF with collagen, L-PRF
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Ridge Preservation
Autologous Blood Products in Ridge Preservation
This randomized controlled clinical trial aims to evaluate the clinical, radiographic, and ultrasonographic outcomes of alveolar ridge preservation using autologous blood products following tooth extraction.
- Trial name
- NCT07530471
- Testing
- Autologous Titanium Platelet-Rich Fibrin with Injectable PRF Application
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Çanakkale Onsekiz Mart University
Thin Gingival Biotype
Efficacy of C-PRF vs i-PRF in Thin Gingival Biotype Subjects
Randomized split mouth clinical trials study focused on comparing the efficacy of i-prf versus c-prf injections on gingival thickness and keratinized tissue width in subjects with thin gingival biotype.
- Trial name
- NCT05615155
- Testing
- Platelets Rich Fibrin (i-PRF / C-PRF)
- Where
- Iraq
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sajjad Ahmed Shakir
Gonarthrosis; Primary
Intra-articular Infiltration of Platelet-Rich Fibrin vs Corticosteroid in Mild to Moderate Knee Osteoarthritis
Methodology: Randomized double-blind clinical trial comparing intra-articular injection of Platelet-Rich Fibrin (PRF) versus intra-articular injection of corticosteroids in mild to moderate arthrosis of the knee.
- Trial name
- iPRF (NCT06905860)
- Testing
- Platelet-rich fibrin (PRF), Corticosteroid
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Interdental Papilla Deficiency
Microneedling-Assisted i-PRF for Interdental Papilla Deficiency
Loss of the gum tissue between teeth can leave visible gaps called black triangles. This study will compare injectable platelet-rich fibrin (i-PRF), prepared from the participant's own blood, with i-PRF combined with…
- Trial name
- MN-iPRF (NCT07907939)
- Testing
- Autologous injectable platelet-rich fibrin (i-PRF), Microneedling of the interdental papilla
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Ehab Ayman Hussien Mohamed Abdelaal
Gingival Recession, Gingival Recession, Localized
The Effect of Using Injectable Platelet-rich Fibrin on Root Surface Closure in Patients with Gingival Recession.
Gingival recession is the term used to describe the apical positioning of the marginal gingiva from the enamel-cementum junction.
- Trial name
- NCT05591326
- Testing
- i-PRF application procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Berceste Guler
TMJ Disc Displacement With Reduction
Hyaluronic Acid and I-PRF Mixture for TMJ Disc Displacement Management
The aim of this study is to evaluate the efficacy of hyaluronic acid and I-PRF mixture for intra-articular injection following arthrocentesis in the management of TMJ reducible disc displacement.
- Trial name
- NCT07683650
- Testing
- 18 joints that receive arthrocentesis using 100 ml of ringer lactate solution, Arthrocentesis followed by hyaluronic acid injection, Arthrocentesis followed by injection of hyaluronic acid and betamethasone mixture
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Mansoura University
Periodontitis Chronic Generalized Severe
Hyaluronic Acid Versus Red Injectable Platelet Rich Fibrin in Treatment of Periodontitis
the aim of this clinical trial is to compare the efficacy of hyaluronic acid (HA) used as an adjunctive to scaling and root planing (SRP) and red injectable platelet rich-fibrin (i-PRF) in the non-surgical treatment of stage III…
- Trial name
- NCT05768243
- Testing
- Hyaluronic acid, red injectable platelet rich fibrin (i-prf)
- Where
- Lebanon
- Volunteers
- 75 people
- Sponsor
- Beirut Arab University
Gingival Recession, Localized
L-PRF Versus Connective Tissue Graft Associated to Coronally Advanced Flap in Gingival Recession Treatment
Background: Nowadays, the use of connective tissue graft associated to the coronally advanced flap is considered the "gold standard" for localized gingival recession treatment.
- Trial name
- NCT04165044
- Testing
- Leukocyte and Platelet Rich Fibrin plus Coronally Advanced Flap, Connective tissue graft plus Coronally Advanced Flap
- Where
- Chile
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Free Gingival Graft, Wound Healing
Chitosan and i-PRF in Palatal Wound Healing
This study aims to evaluate the effects of chitosan and injectable platelet-rich fibrin (i-PRF) on wound healing at the donor site following free gingival graft (FGG) procedures.
- Conditions
- Free Gingival Graft, Wound Healing, i-PRF, Chitosan
- Trial name
- NCT07072546
- Testing
- free gingival graft + gelatin sponge, free gingival graft + chitosan, free gingival graft + chitosan and i-PRF
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Biruni University
Periodontitis
The Effect of I-PRF As An Adjunct to Non-Surgical Periodontal Therapy on Clinical Parameters in Smokers With Periodontitis
The aim of this clinical trial is to evaluate the effect of subgingival injectable platelet-rich fibrin (i-PRF) application on clinical periodontal parameters as an adjunct to non-surgical periodontal treatment (NSPT) in smokers…
- Trial name
- NCT06605547
- Testing
- Non-surgical periodontal treatment, Subgingival application of saline, Subgingival application of i-PRF
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Abant Izzet Baysal University
TMJ Disc Disorder, Treatment
i-PRF for Temporomandibular Joint Disorders
This study will evaluate whether intra-articular injectable platelet-rich fibrin (i-PRF) is more effective than arthrocentesis alone in treating temporomandibular joint (TMJ) disorders.
- Conditions
- TMJ Disc Disorder, Treatment, Arthrocentesis
- Trial name
- NCT07188974
- Testing
- Arthrocentesis (lavage only), Arthrocentesis + Injectable Platelet-Rich Fibrin (i-PRF)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Thin Gingival Biotype
Comparative Evaluation of Vitamin C and Injectable-platelet Rich Fibrin in the Management of Thin Gingival Phenotype
The goal is to compare between the effect of vitamin C and Injectable-platelet rich fibrin in the management of thin gingival phenotype.
- Trial name
- NCT05841303
- Testing
- Vit C, injectable PRF
- Where
- Egypt
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Cairo University
Intra-bony Pockets
The Use of Injectable Plasma Versus the Use of Simvastatin Gel in Surgical Management of Bony Defect in Dentistry
Simvastatin (SMV) is one of the family members of statins, it has been showed in many previous studies that the simvastatin when dissolved with methylcellulose in situ gel with a concentration of 1.2% (SMV) approximately, can…
- Trial name
- NCT04824898
- Testing
- Simvastatin, injectable plasma rich fibrin
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Ain Shams University
Periodontitis, Smokers
This a Clinical Trial to Evaluate the Efficacy of I-PRF, Povidone-Iodine and Laser as Adjuncts to Non-surgical Periodontal Treatment in Smokers and Non-Smokers Periodontitis Patients
This study is a randomized, controlled, split-mouth clinical trial designed to evaluate and compare the effectiveness of four different subgingival adjuncts used along side standard Scaling and Root Planning (SRP).
- Conditions
- Periodontitis, Smokers, Non Smokers, Periodontal Disease
- Trial name
- NCT07707063
- Testing
- Injectable Platelet-Rich Fibrin (I-PRF), Diode Laser Activation, Povidone-Iodine Irrigation (1%)
- Where
- Tunisia
- Volunteers
- 50 people
- Sponsor
- Military Hospital of Tunis
Periodontitis
Effects of PRF and i-PRF on Clinical and Biochemical Parameters in Non-Surgical Periodontal Therapy
The goal of this clinical trial is to learn if adding platelet-rich fibrin (PRF) or injectable platelet-rich fibrin (i-PRF), obtained from the participant's own blood, to standard non-surgical periodontal treatment helps improve…
- Trial name
- PRF-NSPT (NCT07525531)
- Testing
- Non-surgical periodontal therapy (NSPT), Platelet-rich fibrin (PRF), Injectable platelet-rich fibrin (i-PRF)
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Gingival Recession
Evaluation of Sticky Bone With or Without EDTA for Treatment of Gingival Recession
Gingival recession is a common clinical finding in periodontal disease which is frequently associated with esthetic concerns, root hypersensitivity, and root caries.
- Trial name
- NCT04980066
- Testing
- Sticky bone and EDTA, Sticky bone
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Platelet-rich Fibrin
Effect of Injectable Platelet-rich Fibrin on the En Masse Retraction of Maxillary Anterior Teeth
The aim of this study is to investigate the effect of local injection of injectable platelet rich fibrin (i-PRF) on the rate of orthodontic en masse retraction of anterior teeth clinically and to report any associated pain as…
- Trial name
- NCT05608356
- Testing
- injectable platelet rich fibrin(i-prf)
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Necrotic Pulp, Regenerative Endodontic Procedures
Periapical Bleeding Versus PRF Techniques in Regenerative Endodontic Therapy: A Randomized Controlled Trial
This study investigates a biological approach that allows infected and necrotic teeth to heal themselves instead of being treated with traditional root canal therapy.
- Conditions
- Necrotic Pulp, Regenerative Endodontic Procedures, Mature Teeth, Apical Periodontitis
- Trial name
- NCT06886438
- Testing
- RVS, L-PRF, i-PRF
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Saglik Bilimleri Universitesi