Clinical trials: stroke
Spasticity as Sequela of Stroke, Nerve Transfers
Nerve Transfers in Post-stroke Spasticity
Stroke is nowadays a leading cause of disability with devastating sequelae. Upper limb spasticity is one of them. Nevertheless, not all the muscles are equally affected, as some may turn spastic or paretic and other remain…
- Trial name
- NCT04437056
- Testing
- Cognitive nerve transfers to spastic upper extremity muscles in stroke patients
- Where
- Austria
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Stroke
Effectiveness, Safety and Ease of Application of Excel Cryo Cooling Collar to Rapidly Reduce Core Brain Temperature
Research has shown that lowering brain temperature may have good results in heart attack patients. Lowering brain temperature may be a promising treatment for stroke patients.
- Trial name
- CryoCollar (NCT02703675)
- Testing
- Excel Cryo Cooling Collar
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Michel Torbey
Stroke, Stroke Sequelae
Noninvasive VNS to Facilitate Excitability in Motor Cortex
Transcranial Magnetic Stimulation (TMS) positively influences motor rehabilitation in stroke recovery. Transcutaneous auricular vagus nerve stimulation (taVNS) has shown effects on cortical plasticity.
- Conditions
- Stroke, Stroke Sequelae, Motor Activity
- Trial name
- NCT04130646
- Testing
- Transcranial Magnetic Stimulation, transcutaneous auricular vagus nerve stimulation (taVNS)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Atrial Fibrillation
ATRIAL FIBRILATION OPPORTUNISTIC SCREENING AND STROKE (AFOSS).
People: The absolute prevalence of undiagnosed atrial fibrillation in individuals over 60 years of age is 2.2%, equivalent to 20.1% of the overall prevalence of AF and there is not sufficient evidence regarding the procedures…
- Trial name
- AFOSS (NCT03589170)
- Testing
- Opportunistic atrial fibrillation screening
- Volunteers
- 51,410 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Stroke, Spinal Cord Injury
Synergistic Effect of Non-invasive Brain and Spinal Cord Stimulation
The goal of this clinical study is to investigate the potential synergy between non-invasive brain and spinal cord stimulation administered during a cognitive-motor task, in terms of their immediate effects on sensorimotor and…
- Conditions
- Stroke, Spinal Cord Injury, Able Bodied
- Trial name
- BrainSpineStim (NCT07334977)
- Testing
- tDCS, tSCS, Cognitive-Motor Task
- Where
- 2 sites in France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Centre National de la Recherche Scientifique, France
Stroke
Reproducibility Study of Transcranial Doppler
Hardening of the neck vessels (carotid arteries) caused by fatty deposits called 'plaques' is a common cause of strokes. Over time plaques can burst or may lead to a severe narrowing (stenosis) of the neck artery.
- Trial name
- NCT03050567
- Testing
- Transcranial Doppler Ultrasound
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Stroke
Brain Vital Signs M-Score: Point-of-care Monitoring for Motor Recovery After Stroke
The purpose of this study is to investigate brain signals relating to motor function, using electroencephalography (EEG) technology. The aims of the study can be separated into 3 specific study objectives: 1.
- Trial name
- NCT03858699
- Testing
- Recording of electroencephalographic (EEG) data
- Where
- Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- HealthTech Connex Inc.
Chronic Cerebellar Stroke, Healthy Individuals (Controls)
Bimanual Motor Skill Learning Through Robotics in Chronic Cerebellar Stroke Survivors and Healthy Individuals
To test capacity of chronic cerebellar stroke patients and healthy individuals to learn and retain a complex bimanual motor skill, trained on the neurorehabilitation robot REAplan® (bimanual version).
- Trial name
- NCT04642599
- Testing
- Bimanual motor skill learning with the REAplan® rehabilitation robot
- Where
- Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital of Mont-Godinne
Healthy Volunteers, Spinal Cord Injury
Chronic Transcutaneous Stimulation to Promote Motor Function and Recovery in Individuals With Paralysis or Paresis
This is an early feasibility trial to determine whether transcutaneous neuromuscular electrical stimulation, with or without transcutaneous spinal cord stimulation, using an investigational neurostimulation device improves…
- Conditions
- Healthy Volunteers, Spinal Cord Injury, Stroke, Paralysis
- Trial name
- NCT04755699
- Testing
- Transcutaneous Electrical Stimulation
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Neurologic Diseases, Hemiparesis
NuroSleeve Powered Brace & Stimulation System to Restore Arm Function
The purpose of this study is to investigate if a person with weakness or paralysis in one or both arms, can use the NuroSleeve combined powered arm brace (orthosis) and muscle stimulation system to help restore movement in one…
- Conditions
- Neurologic Diseases, Hemiparesis, Quadriplegia, Muscular Dystrophies
- Trial name
- NCT04798378
- Testing
- Neurosleeve
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Stroke
Pushing Spatiotemporal Limits for 4D Flow MRI and Dynamic MRA in the Brain at Ultra-High Field
This study aims at investigating the blood hemodynamics with high spatiotemporal resolution in patients with brain aneurysms and AVMs as well as in healthy controls.
- Trial name
- NCT02576743
- Testing
- 7 Tesla MRI
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Cardiovascular Diseases, Coronary Disease
Cardiovascular Health Study (CHS)
To determine the extent to which known risk factors predict coronary heart disease and stroke in the elderly, to assess the precipitants of coronary heart disease and stroke in the elderly, and to identify the predictors of…
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Cerebrovascular Accident
- Trial name
- CHS (NCT00005133)
- Where
- 6 sites in United States
- Volunteers
- 5,888 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Wheelchair Users, Caregivers
New Rear Anti-tip Device for Manual Wheelchairs: Subjective Input (RAD-SI)
The objective of this study is to obtain subjective input from wheelchair service providers and end-users about their experiences with conventional rear anti-tip devices (C-RADs) of manual wheelchairs and the potential usefulness…
- Conditions
- Wheelchair Users, Caregivers, Wheelchair Service Providers, Amputation
- Trial name
- RAD-SI (NCT06831240)
- Testing
- Local wheelchair service provider questionnaires, Global wheelchair service provider questionnaires, End-users questionnaires
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Cerebrovascular Accident, Healthy
Interhemispheric Interactions Associated With Performance of Voluntary Movements in Patients With Stroke Motor Disability
This study will use transcranial magnetic stimulation (TMS) to identify interactions between the unaffected and affected side of the brain in stroke patients.
- Trial name
- NCT00029718
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Being Between 40-80 Years Old, Being Diagnosed With Haemiplegia
The Relationship Between Lower Limb Functionality, Foot Joint Position Sensation and Balance in Haemiplegic Patients
Stroke is defined as a neurological disorder resulting from acute focal damage to the central nervous system caused by vascular factors, which may include cerebral infarction, intracerebral haemorrhage and subarachnoid…
- Conditions
- Being Between 40-80 Years Old, Being Diagnosed With Haemiplegia, Getting 20 Points or More in the Mini Mental Test, Volunteering to Participate in the Study
- Trial name
- NCT06043960
- Testing
- Humac Norm İsokinetic Machine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Ventricular Tachycardia
MANAGE-VT Registry - MANAGEment of Ventricular Tachycardia Outcomes Registry
Data collection registry for patients with ventricular tachycardia to help physicians give better care for patients clinically and procedurally.
- Trial name
- MANAGE-VT (NCT06455488)
- Testing
- Ventricular Tachycardia Ablation, ICD Implant, Antiarrhythmic drug
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- CorVita Science Foundation
Stroke Not Otherwise Specified, Control Condition
Vessel Angles and Diameters in Stroke Disease
Retrospective analysis of internal carotid artery morphology on CT angiography images of patients with acute ischemic stroke.
- Trial name
- NCT06756724
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Stroke, Awareness
The Investigation of Public Awareness of Core Stroke Symptoms
To investigate public awareness of core stroke symptoms in more than 40 years old population and its related factors.
- Conditions
- Stroke, Awareness, Health Knowledge, Attitudes, Practice, Core Symptoms
- Trial name
- IPACSS (NCT03167346)
- Where
- China
- Volunteers
- 243,279 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
EEG, FNIRS
Investigation of the Possibility of Determining Cerebrovascular Disease Based on Hemodynamic Information of Localized Brain Regions
The purpose of this study is to compare hemodynamic information from localized brain regions between stroke patients and healthy adults using brain activity data (fNIRS and EEG) and to assess the accuracy of early stroke…
- Conditions
- EEG, FNIRS, Stroke, Normal
- Trial name
- NCT06704789
- Testing
- Measurement of brain activity (fNIRS, EEG)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Pusan National University Yangsan Hospital
Cerebral Stroke, Hemiplegia, Spastic
Compensatory Kinematic Movements in Various Directions After Stroke
This is cross-sectional study. By comparing kinematic analysis between stroke and healthy subjects in various directions, this investigation analyzes the compensatory kinematic movement for reaching task in stroke survivors
- Trial name
- NCT05683158
- Where
- South Korea
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Valencia
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