Clinical trials: stroke
Stroke, Stroke, Acute
Looking Glass: Bimanual Balanced Reaching With Visual Biofeedback
The goal of this research study is to increase understanding of error augmentation by applying it to visual feedback during motion tracking with a Leap Motion device - a recently developed optical hand tracking tool - and the…
- Conditions
- Stroke, Stroke, Acute, Healthy
- Trial name
- NCT03300141
- Testing
- Veridical Visual Feedback, Augmented Visual Feedback, Healthy Comparative Reaching Task
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Stroke, Spinal Cord Injury
Synergistic Effect of Non-invasive Brain and Spinal Cord Stimulation
The goal of this clinical study is to investigate the potential synergy between non-invasive brain and spinal cord stimulation administered during a cognitive-motor task, in terms of their immediate effects on sensorimotor and…
- Conditions
- Stroke, Spinal Cord Injury, Able Bodied
- Trial name
- BrainSpineStim (NCT07334977)
- Testing
- tDCS, tSCS, Cognitive-Motor Task
- Where
- 2 sites in France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Centre National de la Recherche Scientifique, France
Surveys and Questionnaires, Evaluation of Processes and Results
Survey Stroke Units in Argentina
Introduction Patients who receive care from stroke units are more likely to survive their stroke, become independent, and return home.
- Conditions
- Surveys and Questionnaires, Evaluation of Processes and Results, Healthcare, Evidence-based Clinical Practice
- Trial name
- NCT06623253
- Testing
- not aplicable
- Where
- Argentina
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hospital de Rehabilitacion Manuel Rocca
Acute Stroke, Ischemic Stroke
Analysing the Effects of Xingnaojing for Mild-to-severe Acute Ischemic Stroke
The main purpose of this trial is to analyse the Effects of Xingnaojing for Mild-to-severe Acute Ischemic Stroke by Metabonomics, proteomics and clinical parameters.
- Trial name
- NCT04813445
- Testing
- Xingnaojing injection
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Dongzhimen Hospital, Beijing
Cardiovascular Diseases, Stroke
Cohort in Qianwan New District, Ningbo
Our objective is to carry out research on prevention and control of noncommunicable chronic diseases, and establish a risk prediction mechanism for chronic diseases to promote early detection, early diagnosis and early treatment…
- Conditions
- Cardiovascular Diseases, Stroke, Non-Communicable Chronic Diseases
- Trial name
- NCT06387875
- Where
- China
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Cardiovascular Diseases, Stroke
Prediction of Primary Cardiovascular Events Using the Multimarker Approach
The study of biochemical risk factors for cardiovascular diseases is important not only for analysis, but also for preventive measures, given that changes in the level of biomarkers can be detected before the first clinical…
- Conditions
- Cardiovascular Diseases, Stroke, Myocardial Infarction, Death
- Trial name
- NCT05704569
- Testing
- measurement of multiple biomarkers
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Karaganda Medical University
Mild Hyperhomocysteinemia
Does B Vitamin Supplementation Decrease Homocysteine Concentrations in Newborns
The purpose of this study is to determine whether supplementation with folinic acid, a B vitamin, lowers the concentrations of total homocysteine in newborns.
- Trial name
- NCT00877227
- Testing
- 5-formyltetrahydrofolate (10 mg/ml) (Pharmachemie bv)
- Where
- Netherlands
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Healthy Volunteer, Stroke
Motivation While Doing Physical Exercise in a Social Dual-task Virtual Environment
The goal of this interventional study is to assess the difference in participants' motivation while performing a virtual reality-based dual-task exercise in a single-player vs. multi-player modality.
- Conditions
- Healthy Volunteer, Stroke, COPD, Cerebral Palsy
- Trial name
- ActivE3 (NCT07050654)
- Testing
- Dual-task cycling
- Where
- 4 sites in Italy
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Istituto di Sistemi e Tecnologie Industriali Intelligenti per il Manifatturiero Avanzato
Stroke
VNS-induced Corticospinal Plasticity
The goal of this study is to learn more about the connections between the brain, spinal cord, and muscles and how these connections can be strengthened after neurological injury.
- Trial name
- NCT04088565
- Testing
- Paired-Associative Stimulation (PAS), Vagus Nerve Stimulation (VNS)
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Healthy
Neuromodulation and Language Acquisition (Project Stage Ia)
The purpose of this study is to determine whether levodopa, pergolid, rivastigmine, or modafinil are effective in boosting semantic language acquisition in healthy subjects.
- Trial name
- NCT00102284
- Testing
- levodopa, rivastigmine, pergolid
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Muenster
Prevention of Stroke or Systemic Embolism, Deep Vein Thrombosis (DVT)
To Compare and Evaluate the Oral Bioavailability of Edoxaban 60 mg Film Coated Tablet With That of Lixiana® 60 mg Filmtabletten (Film Coated Tablet) (Edoxaban) in Healthy, Adult, Human Subjects Under Fasting Conditions
To compare and evaluate the oral bioavailability of Edoxaban 60 mg Film Coated Tablet with that of Lixiana® 60 mg filmtabletten (Film Coated Tablet (Edoxaban) in healthy, adult, human subjects under fasting conditions.
- Conditions
- Prevention of Stroke or Systemic Embolism, Deep Vein Thrombosis (DVT), Pulmonary Embolism (PE)
- Trial name
- NCT06930937
- Testing
- Lixiana® Film Coated Tablet, Edoxaban Film Coated Tablet
- Where
- India
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Humanis Saglık Anonim Sirketi
Aphasia
Intensive Interdisciplinary Treatment Program for Individuals With Stroke-Induced Aphasia
An intensive, interdisciplinary treatment program was administered during the summer as part of regular clinic services in the Aphasia Resource Center (ARC) at Sargent College.
- Trial name
- NCT03096015
- Testing
- Intensive Comprehensive Aphasia Program
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Parkinson Disease, Epilepsy
In Vivo Imaging of Therapeutic Electric Current Flow
The purpose of this research study is to measure current flow inside the head using magnetic resonance imaging (MRI). The data from this study will be used to map the current flow caused from the electrical stimulation inside the…
- Conditions
- Parkinson Disease, Epilepsy, Alzheimer's Disease, Stroke
- Trial name
- tDCS (NCT02453763)
- Testing
- Transcranial direct current stimulation, MRI
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Florida
Stroke
Piloting GETCare: A Remote Goal-based Education and Skills Training Program for Caregivers Poststroke
The purpose of this study was to evaluate the GETCare program, a Goal-based Education and skills Training program for Caregivers poststroke.
- Trial name
- GETCare (NCT05403021)
- Testing
- GETCare Intervention
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Utah
Stroke, Relatives
Survey of Lifelong Food and Nutrition Assistance (LIFANA) in Stroke Patients and Caregivers
Many elderly suffer from nutritional problems that can cause (or can be caused by) a number of complications such as weakened immune systems and chronic health conditions (diabetes type 2, high blood pressure, cardiovascular…
- Conditions
- Stroke, Relatives, Diet Modification
- Trial name
- NCT03635476
- Testing
- Qualitative interview study
- Where
- Switzerland
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Cereneo AG
Stroke
Regaining Confidence After Stroke a Feasibility Randomised Controlled Trial
The Regaining Confidence after Stroke Course (RCAS) is a group therapy intervention to evaluate the feasibility of conducting a definitive trial, aimed to facilitate adjustment for people with stroke discharged from…
- Trial name
- RCAS (NCT03807284)
- Testing
- A group psychosocial course
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
CADASIL
Development and Validation of a Functional MRI Biomarker of Cerebral Small Vessel Dysfunction in CADASIL
Cerebral small vessel diseases (cSVD) are diseases of brain tissue involving vessels (arterioles or capillaries) with a diameter of less than 400 microns.
- Trial name
- fMRI BioSVD (NCT06859658)
- Testing
- Functional MRI at 3T
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obstructive Sleep Apnea, Hypertension
Effect of Selective and Nonselective Cyclooxygenase Enzyme Inhibition on Arterial Blood Pressure and Cerebral Blood Flow With Exposure to Intermittent Hypoxia in Humans
The study has been designed to assess the effect of cyclooxygenase inhibition on blood pressure, cerebral blood flow, ventilation and renal hemodynamics following chronic intermittent hypoxia exposure.
- Conditions
- Obstructive Sleep Apnea, Hypertension, Cardiovascular Diseases, Stroke
- Trial name
- NCT01280006
- Testing
- Intermittent hypoxia, Indomethacin, Celecoxib
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Stroke, Biofeedback
Biofeedback Gait Training by Target Biomechanical Parameters in the Early Recovery Period of Stroke
Single-blinded controlled clinical trial. Biofeedback training courses based on target biomechanical gait parameters are being studied.
- Conditions
- Stroke, Biofeedback, Gait, Hemiplegic, Gait Training
- Trial name
- TargetGait (NCT06299943)
- Testing
- Biofeedback gait training by biomechanical target parameter
- Where
- Russia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Federal Center of Cerebrovascular Pathology and Stroke, Russian Federation Ministry of Health
Stroke
Combined Cognitive and Gait Training
Recent research in gait training for stroke survivors showed that coordinated gait components can be best restored using the following interventions together: coordination exercises, over ground gait training, and body weight…
- Trial name
- CogGait (NCT02362282)
- Testing
- Gait training, cognitive training, Arm training
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development