Clinical trials: stroke
Stroke
Motor Coordination and Grip Strength of the Dominant and Non-dominant Hand and Wrist in Post-stroke Patients.
This study aimed to assess how stabilization of the trunk and the upper extremity can change the parameters of hand/wrist motor coordination and grip strength in dominant and non-dominant paretic upper limb, in post-stroke…
- Trial name
- NCT04889612
- Testing
- hand motor coordination in a sitting positin, hand motor coordination in a supine position
- Where
- Poland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Anna Olczak
Acquired Brain Injury (Including Stroke), Caregivers
Nature in Harmony: Music and Nature-based Self-care for Individuals With Acquired Brain Injuries and Their Care Partners
The goal of this pilot study is to determine the initial impact on wellbeing for clients with acquired brain injury and their care partner after engaging in a nature \& music-based program facilitated by occupational therapy and…
- Trial name
- NCT07568301
- Testing
- Nature in Harmony
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Duquesne University
Stroke, Chronic Stroke
Neural Operant Conditioning
The goal of this clinical trial is to learn if operant conditioning can reduce spasticity in order to improve walking in stroke patient.
- Conditions
- Stroke, Chronic Stroke, Gait, Hemiplegic, Gait, Spastic
- Trial name
- NCT06113965
- Testing
- Peripheral Nerve Stimulation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Aphasia
Effect of Communication Partner Training Program for the Management of Persons With Aphasia
Communication Partner Training (CPT) is an evidence-based intervention that teaches communication partners (e.g., family members, friends, healthcare workers) how to best support conversation and interaction for a person with…
- Trial name
- NCT05225922
- Testing
- Communication Partner Training, Usual Speech and language Therapy
- Where
- Pakistan
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Stroke, Stroke Sequelae
Neural Bases of Post-stroke Emotion Perception Disorders
This monocentric physiological study will evaluate the neural bases of visual recognition of emotions in stroke patients vs. healthy controls using MRI (functional and structural connectivity) and EEG.
- Conditions
- Stroke, Stroke Sequelae, Emotions
- Trial name
- STROKEM (NCT05595005)
- Where
- France
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Upper Limb Deficits
Assessment of Feasibility, Functionality and Usability of an Hybrid Assistive Exoskeleton for Upper Limb
People affected by stroke or brachial plexus injuries experience huge impairment in using upper limbs for everyday life activities.
- Trial name
- NCT07000279
- Testing
- Assistive exoskeleton for activities of daily living (ADLs), Assistive exoskeleton for box and block, Assistive exoskeleton for maximum reaching height
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Istituto Nazionale Assicurazione contro gli Infortuni sul Lavoro
Cerebrovascular Disease, Stroke
Genetic Studies to Identify Stroke Subtypes and Outcome
This study will characterize the gene response of the body's immune and inflammatory cells to stroke. There is a wide variation in stroke risk, stroke outcome, and response to clot-busting therapy for stroke.
- Trial name
- NCT00357513
- Where
- 3 sites in United States
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Stroke
Combined Cognitive and Gait Training
Recent research in gait training for stroke survivors showed that coordinated gait components can be best restored using the following interventions together: coordination exercises, over ground gait training, and body weight…
- Trial name
- CogGait (NCT02362282)
- Testing
- Gait training, cognitive training, Arm training
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Stroke, Healthy Adults
Comparison of Effects of Mirror Therapy Combined With Neuromuscular Electrical Stimulation or Binaural Beats Stimulation on Cortical Excitability, Heart Rate Variability and Lower Limb Motor Function in Patients With Stroke
This study aims to compare the effects of mirror therapy combined with either neuromuscular electrical stimulation or binaural beat stimulation on post-stroke lower limb motor function recovery.
- Trial name
- NCT06011018
- Testing
- Mirror Therapy, Mirror Therapy + Electrical Stimulation, Mirror Therapy + Binaural Beat
- Where
- Taiwan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Acute Ischemic Stroke, Haemorrhagic Stroke
Translational Immunodiagnostics in Stroke (TrImS)
In adult patients presenting to emergency departments within 24 hours of symptom onset with suspected acute stroke, we aim: 1. to identify early brain- and pathology-specific circulating, whole blood, plasma and serum panorOmic…
- Conditions
- Acute Ischemic Stroke, Haemorrhagic Stroke, Transient Ischemic Attacks, Cardioembolic Stroke
- Trial name
- TrImS (NCT05300997)
- Testing
- Biomarker blood draw and saliva collection
- Where
- China
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Stroke, Oral Disease
Oral Health and Vitamin D in Stroke Patients
Stroke is a common, serious and restrictive global health problem. Restricting the activities of daily living of stroke patients impairs patients' ability to pay attention to oral hygiene.
- Conditions
- Stroke, Oral Disease, D Vitamin Deficiency
- Trial name
- NCT05418335
- Testing
- Clinical examination, functional status evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Language Disorders, Aphasia
The Effect of Non-invasive Brian Stimulation on Language Production in Healthy Older Adults
The use of non-invasive brain stimulation techniques like transcranial direct-current stimulation (tDCS) for rehabilitation of language is a growing field that needs further studies to determine how best it can be used to enhance…
- Conditions
- Language Disorders, Aphasia, Stroke
- Trial name
- NCT04260815
- Testing
- Transcranial direct-current stimulation (tDCS)
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- King's College London
Stroke
Modulation of Cortical Gamma Synchrony in Stroke
In the last decades, the research in neuroimaging-informed stroke prognosis and treatment has had a little clinical impact, often because of the costs of bringing complex procedures to the bedside.
- Trial name
- GAMMASTROKE (NCT05830617)
- Testing
- real tACS
- Where
- Italy
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Stroke
Transformation of Somatosensory and Visual Coordinate Systems
Manipulation of object is a multisensory experience that includes tactile motion between the object and the fingerpad, visual motion elicited by the motion the object and the movement of the hand, and the active motor commend to…
- Trial name
- NCT01177462
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Acute Stroke
Ischemic Conditioning During Air tRansport Save penUmbral Tissue
The purpose of this study is to demonstrate the feasibility of performing remote limb ischemic conditioning (RLIC) using the Doctormate device, a special blood pressure device used to perform RLIC, on patients with acute ischemic…
- Trial name
- ICARUS (NCT03481205)
- Testing
- Ischemic conditioning device
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Enrique Leira
Spasticity as Sequela of Stroke, Nerve Transfers
Nerve Transfers in Post-stroke Spasticity
Stroke is nowadays a leading cause of disability with devastating sequelae. Upper limb spasticity is one of them. Nevertheless, not all the muscles are equally affected, as some may turn spastic or paretic and other remain…
- Trial name
- NCT04437056
- Testing
- Cognitive nerve transfers to spastic upper extremity muscles in stroke patients
- Where
- Austria
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Stroke, Spinal Cord Injury
VIT-ARMin Virtual, Intensified and Patient-tailored Robotic Arm Therapy With the Exoskeleton Robot ARMin
Consideration-of-Concept Trial (stage 1) on robotic therapy of the upper extremity with the ARMin therapy robot in healthy subjects and patients with neurological disease (e.g. stroke, spinal cord injury)
- Conditions
- Stroke, Spinal Cord Injury, Healthy
- Trial name
- VIT-ARMin (NCT02720341)
- Testing
- ARMin
- Where
- 3 sites in Switzerland
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Stroke
A Caregiver-Assisted Rehabilitation With Strategy Training (CAR-ST) for Stroke Patients
The goal of this randomized controlled trial is to examine if involving the caregivers in the strategy training (i.e. caregiver-assisted rehabilitation with strategy training, CAR-ST) works to improve activity functions in…
- Trial name
- CAR-ST (NCT06754566)
- Testing
- Caregiver-Assisted Rehabilitation with Strategy Training, Strategy Training, Education
- Where
- 5 sites in Taiwan
- Volunteers
- 261 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Stroke
Inpatient Stroke Recovery Using Sensors
This observational trial seeks to assess the feasibility of using non-invasive, portable, real-time body-worn sensors to continuously monitor, quantify, and interpret recovery during inpatient treatment of stroke
- Trial name
- NCT04219670
- Testing
- Wearable sensors
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Stroke
Effect of Neural Constraints on Movement in Stroke
This study investigates the effects of Tizanidine on the voluntary movement controls of the arms of participants who have had a stroke and have not had a stroke by measuring medication-induced changes in upper extremity…
- Trial name
- ENCMS (NCT06666673)
- Testing
- Tizanidine
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Northwestern University
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