Clinical trials: stroke
Aphasia
Based on the Spatio-temporal Coding Characteristics of Frontotemporal Network, This Paper Explores the Mechanism of Five-tone Speech Training in Reshaping Language Fluency Function.
To explore the mechanism of five-tone speech training in reshaping language fluency function and the clinical efficacy of aphasia language function, daily communication ability and communication efficiency based on the temporal…
- Trial name
- NCT07329751
- Testing
- Traditional Chinese Medicine Five-Tone Therapy, Melodic Intonation Training, Standard speech therapy; Routine medical treatment; Health education
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fujian University of Traditional Chinese Medicine
Acute Ischemic Stroke
Arterial Spin Label Depicted Ischemic Stroke Cohort (ASLIS)
Establish a clinical cohort of acute ischemic stroke patients and find the determinant of the prognosis.
- Trial name
- ASLIS (NCT05920902)
- Testing
- routine therapy of acute ischemia stroke
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
Acute Stroke
Investigation of the Reliability and Validity of the Movement Imagination Questionnaire - Revised Second in Acute Stroke Patients
Our study was planned to investigate the reliability validity of the Movement Imagery Questionnaire- RS in acute stroke patients.
- Trial name
- NCT04283760
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Cerebral Palsy, Stroke
A Longitudinal Study of Motor Control and Brain Images in Patients With Brain Damage
The primary goal of this study is to establish and evaluate an image-based biomarker for the impaired motor control and sensory information processing present in Cerebral palsy (CP) and stroke patients.
- Trial name
- NCT01883960
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Atherosclerosis, Cardiovascular Diseases
Atherosclerosis, Plaque and CVD in Communities
To identify new cellular, metabolic, and genomic correlates of atherosclerotic plaque and early pathologic changes in the vascular wall and determine their consequences for coronary heart disease and stroke.
- Conditions
- Atherosclerosis, Cardiovascular Diseases, Heart Diseases, Cerebrovascular Accident
- Trial name
- NCT00091754
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Cardiovascular Diseases, Stroke
Prediction of Primary Cardiovascular Events Using the Multimarker Approach
The study of biochemical risk factors for cardiovascular diseases is important not only for analysis, but also for preventive measures, given that changes in the level of biomarkers can be detected before the first clinical…
- Conditions
- Cardiovascular Diseases, Stroke, Myocardial Infarction, Death
- Trial name
- NCT05704569
- Testing
- measurement of multiple biomarkers
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Karaganda Medical University
Stroke, Walking, Difficulty
Turning Dysfunction After Stroke: Assessment and Intervention
The study aims to investigate the 1) differences between stroke patients and healthy controls in time, steps, angular velocity, stepping patterns, electromyographic responses during turning, and the association of turning to…
- Conditions
- Stroke, Walking, Difficulty, Balancing Interference
- Trial name
- NCT04668573
- Testing
- Trunk exercise
- Where
- Taiwan
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Stroke
Validity and Reliability of the Virtual Reality-Based 9-Hole Peg Test in Stroke Patients
The goal of this observational study is to demonstrate diagnostic value of a VR-based 9-hole peg test (9HPT) for the evaluation of manual dexterity in stroke patients.
- Trial name
- NCT06583772
- Testing
- VR-based 9-hole peg test
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Ankara University
Stroke
Stroke Upper Limb Rehabilitation With Robot Operators: a Synergistic Approach for Human-Robot Interaction and Rehabilitative Trials.
In clinical scenario, clinical scales and kinematic analysis are usually used for the evaluation of patients. However, these methods are limited, since they may suffer from the lack of objectivity and sensitivity.
- Trial name
- SULLRO (NCT07768683)
- Testing
- Upper Limb robotic training
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Villa Beretta Rehabilitation Center
Stroke
Sensory Feedback and Hand Motor Adaptation
The following experiment will be conducted with 15 chronic stroke survivors and 15 control subjects. Subjects will perform hand movements in the virtual reality environment using a head-mounted display.
- Trial name
- NCT07598695
- Testing
- Visual ROM augmentation, Visual ROM reduction
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Catholic University of America
Stroke
Cognitive & Motor Training After Stroke For Everyday Walking Restoration
The purpose of this study is to test a unique, combined cognitive and motor intervention designed to restore safe, more normal coordinated gait components into the real world environment for individuals with stroke.
- Trial name
- NCT01160653
- Testing
- FES-IM, Cognitive training
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Myocardial Infarction, Stroke, Ischemic
Study of Circulating Monocytes in Patients With Ischemic Vascular Disease
The purpose of this research study is to discover the functions of circulating white blood cells, called monocytes, and associated circulating substances in heart attack and ischemic stroke patients.
- Conditions
- Myocardial Infarction, Stroke, Ischemic, Ischemia
- Trial name
- NCT04321512
- Testing
- There is no intervention given to the subjects
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- UConn Health
Acute Coronary Syndromes (ACS), Recent Myocardial Infarction
The Pharmacokinetics and Pharmacodynamics Study of Evategrel CG-0255 Besylate）and Plavix® in Healthy Participants
CG-0255 is a novel investigational prodrug of the active metabolite of Plavix®， but with different active metabolite conversion routes.
- Conditions
- Acute Coronary Syndromes (ACS), Recent Myocardial Infarction, Recent Stroke, Peripheral Arterial Disease
- Trial name
- NCT07619885
- Testing
- CG-0255 Besylate for Injection, CG-0255 Besylate Capsule, Clopidogrel
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Shanghai CureGene Pharmaceutical Co., Ltd.
Stroke
Individualized rTMS Protocol for Stroke Recovery
This study aims to develop individualized therapeutic protocol to improve stroke recovery and fits the scheme of Mechanisms, biomarkers, and treatment strategies for stroke, aging, and Parkinson's disease by advanced EEG analysis…
- Trial name
- NCT03828435
- Testing
- rTMS
- Where
- Taiwan
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Stroke
Ultrasonographic Evaluation of Morphological and Functional Characteristics of Intercostal Muscles in Stroke Patients and Their Relationship With Clinical Parameters
The aim of this study is to evaluate the morphological and functional characteristics of parasternal intercostal muscles in patients with stroke using ultrasonography.
- Trial name
- NCT07670585
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Marmara University
Stroke
The Effects of Inspiratory Pressures on Diaphragmatic Contraction in People After Stroke
This is a cross-sectional study to determine the optimal inspiratory muscle training (IMT) intensity for stroke survivors. Participants will breathe through a pressure threshold inspiratory loading device with varying loads in…
- Trial name
- NCT06267768
- Testing
- Various intensities of inspiratory muscle training
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hong Kong Metropolitan University
Healthy, Spastic Hemiparesis
Soleus Loading Response During Walking
Stroke survivors experience motor deficits, weak voluntary muscle activations, and low weight-bearing capacity that impair ambulation.
- Conditions
- Healthy, Spastic Hemiparesis, Stroke
- Trial name
- NCT05436366
- Testing
- Soleus loading response in able-bodied participants, Soleus loading response in participants with hemiparesis
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Victor H. Duenas
Cardiovascular Disease, Heart Disease
Chocolate and CVD Risk in Postmenopausal Women
The investigators will conduct an epidemiological analysis of data from the Women's Health Initiative to investigate the prospective association between chocolate intake and the risk of heart disease and stroke.
- Conditions
- Cardiovascular Disease, Heart Disease, Stroke
- Trial name
- NCT03453073
- Testing
- chocolate consumption level, physician diagnosis of first occurrence of serious chronic disease
- Volunteers
- 83,310 people, healthy volunteers welcome
- Sponsor
- Brooklyn College of the City University of New York
Stroke
Single and Repeat Doses of DMT in Healthy Subjects
This study aims to assess the safety and tolerability of single ascending, and fixed repeated doses of N,N-Dimethyltryptamine (DMT) in healthy subjects, when given by intravenous (IV) infusion.
- Trial name
- NCT05559931
- Testing
- N,N-Dimethyltryptamine
- Where
- Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Algernon Pharmaceuticals
Stroke
The Effect of GLP-1 Receptor Agonist on Cerebral Blood Flow Velocity in Non-stroke Volunteers
This randomized controlled trial investigates the effect of a single dose of glucagon-like peptide-1 (GLP-1) receptor agonist on cerebral blood flow velocity and cortical oxygination in humans without cerebrovascular disease.
- Trial name
- EGRABINS1 (NCT02838589)
- Testing
- Byetta, Isotonic saline
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Christina Kruuse
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