Clinical trials: v
Breast Cancer
CRRS-4 Pivotal Somo•v™ ABUS ROC Reader Observer Study
To determine the impact on Interpreting Physician performance in detecting breast cancer, as defined by the area under the Receiver Operating Characteristic Curve (ROC), when Automated Breast Ultrasound (ABUS) and screening…
- Trial name
- NCT01424956
- Testing
- Automated Breast Ultrasound (ABUS)
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- U-Systems, Inc.
Healthy
A Comparative Study of New Formulation and Approved Formulation for Levothyroxine in Healthy Volunteers
The study investigated the bioequivalence between the new and the approved formulation for levothyroxine.
- Trial name
- NCT03979274
- Testing
- Reference Eutirox®, Test Eutirox®
- Where
- Mexico
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
Factor V Leiden, Prothrombin G20210A
A Single Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of CITY-FXI in Healthy Adults, Adults With FV Leiden or Prothrombin G20210A Mutation, and Adults With a History of Provoked Venous Thromboembolism
This is a first-in-human (FIH), single-center, randomized, double-blind, placebo-controlled, single ascending and multiple dose study evaluating the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of…
- Conditions
- Factor V Leiden, Prothrombin G20210A, Venous Thromboembolism (VTE)
- Trial name
- NCT07430397
- Testing
- CITY-FXI
- Where
- United Kingdom
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- City Therapeutics
Dental Restoration Failure of Marginal Integrity
Different Application Strategies When Using Ambar Universal in Class V Cavities
Treatment clinical trial, randomized, controled, parallel, double-blinded, with four groups, that aims to evaluate the best application strategy when using a new Universal Adhesive system, Ambar Universal (FGM, Joinville…
- Trial name
- AUC (NCT02948686)
- Testing
- Self-Etching Application Strategy, Enamel Etching Application Strategy, Self Etching with Extended time Application Strategy
- Where
- Brazil
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Healthy Subject, Pancreatic Carcinoma
Integrin Alpha-v-Beta and [18F]-R01-MG-F2 PET/CT in Measuring Response in Patients With Pancreatic Cancer and Healthy Volunteers
This pilot clinical trial studies the use of integrin alpha-v-beta [18F]-R01-MG-F2 Positron Emission Tomography/Computed Tomography (PET/CT) and Positron Emission Tomography-Magnetic Resonance Imaging in (PET/MRI) in measuring…
- Trial name
- NCT02683824
- Testing
- Computed Tomography, Laboratory Biomarker Analysis, PET/MRI scan
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Stanford University
Diabetes Mellitus
Compare Blood Sugar Level Between Lantus in the Morning and Other Insulins in Type 1 Diabetes Adolescents
The purpose of the study is to compare the effect in blood sugar control between Lantus and twice daily intermediate acting insulins (NPH or Lente) when used as the basal insulin in a multiple daily injection setting with fast…
- Trial name
- NCT00046501
- Testing
- Lantus (insulin glargine [rDNA origin] injection), Humulin N, Humulin L
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Sanofi
Inflammation, Atherosclerosis
Effects of Short-term Curcumin and Multi-polyphenol Supplementation on the Anti-inflammatory Properties of HDL
Polyphenol supplements, including curcumin and resveratrol, are known to decrease inflammation, but previous polyphenol supplements were poorly absorbed and thus their effects were reduced.
- Conditions
- Inflammation, Atherosclerosis, Cardiovascular Disease
- Trial name
- PSI (NCT02998918)
- Testing
- PolyResveratrol Supplementation, Curcumin Supplementation
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Skin Aging, Facial Wrinkles
Study of the Subdermal Implant "Ultracol"
Study of the effectiveness of the medical device "Intradermal implant, sterile ULTRACOL based on polydioxanone (ULTRA V Co., Ltd., Korea) in the correction of skin contour defects.
- Conditions
- Skin Aging, Facial Wrinkles, Senile Skin Atrophy, Lipodystrophy
- Trial name
- NCT07617350
- Testing
- Administration of the prepared solution - 1 time Post injection observation - 30, 60, 160 days from the date of the first injection.
- Where
- Russia
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Estelab Clinic
Orthodontic Appliance Complication, Orthodontic Appliance Design
Periodontal and Orthodontic Outcomes of Straight vs. Looped Fixed Retainers
The goal of this split-mouth, head-to-head, randomized controlled trial is to compare the effects of a fixed straight retainer with the V- loop bonded retainer on periodontal health in patients with the requirement of continuous…
- Conditions
- Orthodontic Appliance Complication, Orthodontic Appliance Design, Orthodontic Treatment
- Trial name
- NCT05644119
- Testing
- V- loop Bonded Orthodontic Retainer, Straight Wire Retainer
- Where
- Saudi Arabia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Use of the Vloc Suture, Elevation of the Mid-face
Use of V-Loc Suture for Mid-face Lifting in Short-flap Rhytidectomy
This study will evaluate and measure the Vloc suture's ability to elevate the mid-face when using a short flap, short incision technique in during a traditional face-lift.
- Trial name
- NCT02023307
- Testing
- V-Loc Suture
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Lifestyle Lift
Glucose Metabolism Disorders
Interaction of MTNR1B Genotype and Type of Breakfast (Protein-enriched v Carbohydrate-rich) on Postprandial Glucose Response.
The risk version of the MTNR1B gene (which codes for a melatonin receptor) has been associated with type II diabetes (T2D) and associated physiological markers.
- Trial name
- NCT06821620
- Testing
- Breakfast
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- St. Mary's University, Twickenham
COVID-19
Study in Adults of AZD1222 and rAd26-S Administered as Heterologous Prime-Boost Regimen for the Prevention of COVID-19
The objective is to evaluate the safety and immunogenicity of AZD1222 given in combination with (either before or after) rAd26-S, for the prevention of COVID 19 in adults ≥ 18 years of age.
- Trial name
- NCT04684446
- Testing
- AZD1222, rAd26-S
- Where
- 4 sites in Russia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- R-Pharm
Weakness, Muscle, Muscle Tightness
Pilates Exercises v/s Yoga on Rounded Shoulders
To Compare the effects of Pilates exercises an yoga on rounded shoulders
- Conditions
- Weakness, Muscle, Muscle Tightness, Range of Motion, Pain
- Trial name
- NCT05876650
- Testing
- Pilates exercises, Yoga
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
COVID-19 Vaccine
Phase IIB Study of Recombinant Novel Coronavirus Vaccine
This is an open-label and non-randomized study to demonstrate the immunogenicity and safety profile in adults that received the Ad5-nCoV vaccine at least 21 days but no later than 90 days after the first dose of Sputnik V.
- Trial name
- FH-63 (NCT05293223)
- Testing
- Ad5-nCov
- Where
- 3 sites in Argentina
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Fundación Huésped
Healthy
A Relative Bioavailability Study of Griseofulvin 125 mg/5 mL Suspension Under Fasting Conditions
To compare the rate and extent of absorption of griseofulvin from a test formulation of Griseofulvin 125 mg/5 mL Suspension versus the reference Grifulvin V® 125 mg/5 mL Suspension under fasting conditions.
- Trial name
- NCT00864071
- Testing
- Griseofulvin 125 mg/5 mL Suspension, single dose, Grifulvin V® 125 mg/5 mL Suspension, single dose
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Actavis Inc.
Bracket Failure, Bracket Bonding
Comparison of Bond Failure Rate of Orthodontic Brackets Bonded With V-Prep and Resin-Modified Glass Ionomer Cement Versus Conventional Acid-Etch Composite Resin
Ethical approval will be obtained by the FUSH and informed consent will be obtained from individual patients/guardians in writing.
- Conditions
- Bracket Failure, Bracket Bonding, RMGIC, Conventional Bracket Bonding
- Trial name
- NCT07828431
- Testing
- V-Prep and Resin-Modified Glass Ionomer Cement, Conventional Acid-Etch Composite Resin
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Endometriosis
Evaluation of New Biomarkers in Stage 3 and 4 Endometriosis
The diagnostic value of Annexin V, sVCAM-1, sICAM-1, vascular endothelial growth factor and Proinflammatory cytokines (TNF-a and interleukin-6) in ovarian endometriosis and deep infiltrating endometriosis, their levels in…
- Trial name
- NCT05312528
- Testing
- endometriosis surgery, other benign condition surgeries
- Where
- Turkey (Türkiye)
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Bagcilar Training and Research Hospital
Class V Dental Caries
Clinical Evaluation of Giomer Based Injectable Resin Composite Versus Resin Modified Glass Ionomer in Class V Carious Cavities Over 18-months.
Class V carious lesions will be restored using either Resin modified glass ionomer or Giomer based injectable resin composite.The restorations will be evaluated at baseline and regular recalls of 3 months, 6 months, 12 months and…
- Trial name
- NCT05389163
- Testing
- Giomer based injectable resin composite, Resin modified glass ionomer
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hypoxia, Bariatric Surgery
The Relationship Between Postoperative Oxygenation and STOP-BANG Questionnaire and 4-V Tool
In our study, we aimed to investigate the relationship between STOP-BANG and 4-Variable Screening questionnaires in postoperative period in patients who underwent bariatric surgery.
- Trial name
- NCT03838705
- Testing
- hypoxia, normooxy
- Where
- Turkey (Türkiye)
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Umraniye Education and Research Hospital
Colon Cancer Screening
Colonoscopy Bowel Prep Comparison Among Diabetic Patients
The goal of this clinical trial is to learn if the Golytely or SUPREP bowel preparation works more effectively in bowel cleansing for colorectal cancer screening with colonoscopy in patients with diabetes.
- Trial name
- NCT07351019
- Testing
- Golytely, SUPRPEP
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Eisenhower Army Medical Center