Clinical trials: in Cambodia
Core Competency, Patient Safety
Procedure Manual-Based Simulation Training to Improve Operating Room Nurses' Core Competencies
This study aims to evaluate the effectiveness of a procedure manual-based simulation training program in improving the core competencies of operating room nurses in a Cambodian national hospital.
- Conditions
- Core Competency, Patient Safety, Interprofessional Collaboration, Surgical Outcome
- Trial name
- NCT07527429
- Testing
- Procedure Manual-Based Simulation Training
- Where
- Cambodia
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Hiroshima University
Dengue, Sepsis
Immune Responses to Dengue and Sepsis
The goal of this research study is to help the investigators better understand serious dengue disease. The investigators will collect clinical information and up to four blood samples from participants with dengue, influenza…
- Conditions
- Dengue, Sepsis, Influenza
- Trial name
- DEN-SEP (NCT07040202)
- Where
- 4 sites in Cambodia
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur du Cambodge
Melioidosis
Environment, Pathogens, and Host Interactions in Melioidosis
This is a longitudinal, multicentre observational study conducted across three established microbiology units integrated within hospital and community health systems in Thailand, Lao PDR, and Cambodia.
- Trial name
- DeEPH (NCT07345910)
- Where
- 3 sites in Cambodia, Laos and 1 more
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Vector-Borne Diseases, Emerging Pathogens
Febrile Disease Landscape in Cambodia Via Metagenomic Pathogen Sequencing
Background: Vector-borne diseases are caused by the bite of an infected mosquito, fly, flea, tick, or other blood-feeder. These diseases cause almost 1 million deaths per year.
- Trial name
- NCT04034264
- Where
- 6 sites in Cambodia
- Volunteers
- 6,500 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Maternal and Child Health
An Innovative Mobile Technology Intervention for Maternal and Child Health Care in Cambodia
The Innovative Mobile Technology for Maternal and Child Health Care (i-MoMCARE) project is a digital health intervention aiming to increase the coverage of and access to maternal and child health (MCH) services for pregnant women…
- Trial name
- i-MoMCARE (NCT05639595)
- Testing
- Web interface for health center staff and mobile application on smart phones for village health volunteers
- Where
- Cambodia
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Hospital-acquired Infections
Infection Prevention and Control Intervention to Reduce Hospital-acquired Infections
Hospital-acquired infections (HAIs) are significant public health issues, especially in low- and middle-income countries (LMICs).
- Trial name
- IPC-HAI (NCT05547373)
- Testing
- Infection prevention and control (IPC)
- Where
- Cambodia
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Human Papillomavirus Vaccination, Cervical Cancer Prevention
Integrating HPV Education Into School Health Programs in Cambodia and Kenya
The Clinton Health Access Initiative conducted a mixed-methods, school-based interventional study in Cambodia and Kenya to evaluate whether integrating age-appropriate human papillomavirus (HPV) education into existing school…
- Trial name
- NCT07784283
- Testing
- Integrated HPV Education
- Where
- 5 sites in Cambodia, Kenya
- Volunteers
- 9,054 people, healthy volunteers welcome
- Sponsor
- Clinton Health Access Initiative Inc.
Immunity, Humoral
Characterization of Human Immune Signatures to Zoonotic Virus Exposure in Cambodia
This is a biospecimen procurement protocol to characterize the immune response to zoonotic virus exposure in healthy adult humans aged 18 to 65 years with high-risk exposure to animals or their excreta (e.g., guano farming and…
- Trial name
- Camzoo (NCT06680843)
- Testing
- Whole blood collection
- Where
- 5 sites in Cambodia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Exposure to Environmental Pollution, Exposure to Household Air Pollution
Applied Implementation Research for Clean Cooking in Cambodia
The goal of this study is to learn how to help families in Cambodia switch to using electric induction stoves instead of traditional stoves that burn wood or charcoal.
- Trial name
- AIR-C3 (NCT06942715)
- Testing
- Electric Induction Cookstoves
- Where
- Cambodia
- Volunteers
- 6,150 people, healthy volunteers welcome
- Sponsor
- Emory University
Perinatal Mortality
Saving Babies Lives
The central hypothesis of this study is that a neonatal healthcare programme that has a significant impact on neonatal mortality and which spans the healthcare journey from village to referral hospital can be developed and…
- Trial name
- SBL (NCT04663620)
- Testing
- Saving Babies Lives Programme, No Saving Babies Lives Programme
- Where
- Cambodia
- Volunteers
- 24,040 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Cause of Mortality, Cause of Neonatal Death
Defining Causes of Deaths in South and Southeast Asia
Brief Summary: Mortality data are important in low and middle-income countries to assess the population health status and trends.
- Conditions
- Cause of Mortality, Cause of Neonatal Death, Cause of Child Death, Cause of Maternal Death
- Trial name
- SEACTN-VA (NCT04595656)
- Testing
- verbal autopsy interview
- Where
- 5 sites in Bangladesh, Burma and 3 more
- Volunteers
- 3,413 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Anemia, Pregnancy
Assessing Health System Readiness for Scaling Antenatal MMS in Cambodia
Malnutrition among pregnant women in low- and middle-income countries (LMICs) can cause micronutrient deficiencies that result in adverse maternal and neonatal health outcomes.
- Conditions
- Anemia, Pregnancy, Micronutrients, Supplement
- Trial name
- TIPS-Cambodia (NCT07400796)
- Testing
- Multiple micronutrient supplement (MMS) for pregnancy
- Where
- Cambodia
- Volunteers
- 710 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Dengue, Chikungunya
Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective
RACSMEI addresses the high burden of infectious diseases in low- and middle-income countries, including Cambodia, where limited surveillance and laboratory capacity often obscure etiologies and transmission dynamics.
- Conditions
- Dengue, Chikungunya, Zika Virus Infection, Japanese Encephalitis
- Trial name
- RACSMEI (NCT07358910)
- Where
- Cambodia
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur du Cambodge
Rehabilitation, Physical Therapy
The Combined FIFA 11+ and Change of Direction Training
The study has investigated the effects of adding change of direction (COD) training to the FIFA 11+ on lower extremity performance in soccer players.
- Trial name
- NCT06262087
- Testing
- Change of direction training, FIFA 11+ program
- Where
- Cambodia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Hepatitis C, Testing
Community Versus Facility-based Services to Improve the Screening of Active HCV Infection in Cambodia
Objectives Principal objective: to compare the effectiveness of a community-based intervention to a facility-based intervention to improve the combined-testing uptake (Antibody + RNA) of HCV infection among general population…
- Trial name
- Cam-C (NCT03992313)
- Testing
- Community-based HCV rapid test, Facility-based HCV rapid test, Plasmatic HCV viral load
- Where
- 2 sites in Cambodia
- Volunteers
- 7,692 people, healthy volunteers welcome
- Sponsor
- ANRS, Emerging Infectious Diseases
Malaria
Repellents as Added Control Measure to Long Lasting Insecticidal Nets
The scaling up of Long Lasting Insecticidal Nets (LLIN) and the expansion of Indoor Residual Spraying (IRS) has contributed to a significant decrease of malaria worldwide.
- Trial name
- MalaResT (NCT01663831)
- Testing
- Mosquito topical repellent
- Where
- Cambodia
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Institute of Tropical Medicine, Belgium
Febrile Illness
Village Malaria Worker Expansion
This project will conduct pragmatic operational research in rural communities served by approximately 12 health centres and 120 village malaria workers in Battambang/Pailin, western Cambodia.
- Trial name
- CAM-VMW (NCT05045547)
- Where
- Cambodia
- Volunteers
- 7,191 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Hospital Infections, Environment, Controlled
CLEAN Frontline: A Stepped Wedge Cluster Trial
Environmental hygiene is a key component of infection prevention in healthcare, and a driver of healthcare associated infections.
- Conditions
- Hospital Infections, Environment, Controlled, Infection Control
- Trial name
- NCT05540886
- Testing
- TEACH CLEAN
- Where
- Cambodia
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Pregnancy Related, Antenatal Care
Multiple Micronutrient Supplementation vs Iron and Folic Acid Among Pregnant Women in Cambodia
Iron and folic acid (IFA) supplements are currently provided to Cambodian women during pregnancy. However, recent research has showed benefit of a multiple micronutrient supplement (MMS) over just IFA alone on several outcomes of…
- Conditions
- Pregnancy Related, Antenatal Care, Iron Folic Acid Supplementation
- Trial name
- MMS-Cambodia (NCT05867836)
- Testing
- IFA vs. MMS during pregnancy
- Where
- Cambodia
- Volunteers
- 1,545 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Anemia, Iron Deficiency, Anemia
Potential Harms of Untargeted Iron Supplementation in Cambodia Where Iron Deficiency is Not the Cause of Anemia
In 2016, the World Health Organization (WHO) set a global policy recommending daily oral iron supplementation (60 mg iron) for 12 weeks for all women living in countries where anemia prevalence is >40%, such as in Cambodia.
- Conditions
- Anemia, Iron Deficiency, Anemia, Intestinal Inflammation, Inflammation
- Trial name
- NCT04017598
- Testing
- Ferrous sulfate, Ferrous Bisglycinate
- Where
- Cambodia
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- University of British Columbia