Clinical trials: in Ecuador
Symptoms of Depression and Anxiety
Mindfulness Intervention Using Virtual Reality in Older Adults With Symptoms of Anxiety and Depression in Ecuador
The availability of affordable hardware and rapidly growing content that can be freely accessed in the public domain raises the possibility of VR being used across the world globally and, in a very broad range of settings…
- Trial name
- NCT06219642
- Testing
- Mindfulness using virtual reality
- Where
- Ecuador
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Universidad San Francisco de Quito
High-risk Cardiac Patients
Registry Study for the Evaluation of High-risk Cardiac Patients by WILLEM AI-based ECG Platform
The WILLEM Registry is a large-scale, single-group, observational, registry study to collect continuous clinical evidence of Willem in real-world settings.
- Trial name
- WILLEMRegistry (NCT07333547)
- Testing
- Willem AI ECG assessment
- Where
- 5 sites in United States, Ecuador and 1 more
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- Idoven 1903 S.L.
Bone Substitutes, Alveolar Bone Grafting
Bone Augmentation Techniques in the Mandible Posterior Region
This study will compare three methods to rebuild lost bone in the back part of the lower jaw (posterior mandible) before dental implant placement.
- Trial name
- NCT06661447
- Testing
- Cortical Shell Bone Grafting
- Where
- Ecuador
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Universidad de Especialidades Espiritu Santo
Social Isolation in Older Adults, Loneliness
Community-Based Social Connection Intervention Program to Improve Cardiovascular and Brain Health
This study evaluates the effectiveness of a community-based social connection intervention program (SCIP) designed to reduce social isolation and loneliness and improve cardiovascular and brain health among older adults living in…
- Conditions
- Social Isolation in Older Adults, Loneliness, Stroke, Cognitive Decline
- Trial name
- NCT07319663
- Testing
- Social Connection Intervention Program (SCIP): Community activities, peer-support groups, and home-based coaching to reduce social isolation and loneliness.
- Where
- Ecuador
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Universidad de Especialidades Espiritu Santo
Pediatric Sleep Problems, Sleep Hygiene
Storybook App vs Cognitive Behavioral Therapy for Child Sleep and Attachment
This completed randomized controlled trial compared two caregiver-delivered interventions for sleep in young children: a multimodal mobile health intervention delivered through the Storybook mobile application and a face-to-face…
- Conditions
- Pediatric Sleep Problems, Sleep Hygiene, Parent-Child Attachment
- Trial name
- STORYBOOK-RCT (NCT07668609)
- Testing
- CBT-Based Psychoeducational Intervention, Storybook Mobile Application Intervention
- Where
- Ecuador
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad Católica de Cuenca
Diabetic Nephropathy, Diabetes Mellitus
Mechanisms of Diabetic Nephropathy in Ecuador
The prevalence of diabetes mellitus (DM) is increasing worldwide, suggesting that 45% of diabetics are undiagnosed. DM induces a kidney disease called diabetic nephropathy (DN) which is the largest single cause of end-stage renal…
- Conditions
- Diabetic Nephropathy, Diabetes Mellitus, Kidney Diseases, Diabetic Kidney Disease
- Trial name
- NCT02237352
- Where
- Ecuador
- Volunteers
- 10,064 people, healthy volunteers welcome
- Sponsor
- Universidad Estatal de Milagro
Mental Health Literacy
Roots for Life Project: Strengthening Mental Health in School Communities
This pilot study, titled "Roots for Life Project: Strengthening Mental Health in School Communities", aims to evaluate the feasibility and preliminary effectiveness of a mental health literacy (MHL) intervention for teachers and…
- Trial name
- NCT07564635
- Testing
- Child Mental Health Literacy Program
- Where
- 3 sites in Chile, Ecuador
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universidad de Valparaiso
Dental Caries, Tooth Demineralization
Kissing as a Protective Factor Against Acidic pH in Saliva
The pH of saliva can be acidic or alkaline; When it is acidic, the tooth enamel is demineralized, that is, weakened. Additionally, bacteria in the mouth can increase and cause infections such as cavities.
- Conditions
- Dental Caries, Tooth Demineralization, Teeth Erosion Limited to the Enamel
- Trial name
- NCT06501729
- Testing
- Kiss
- Where
- Ecuador
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Universidad Catolica Santiago de Guayaquil
Adolescent Development, Mental Health Issue
GENESIS Project: Generating Evidence on the Needs of Ecuadorian Adolescents
Background: Adolescence is a period of intensified emotional responses and occurs when mental health disorders commonly develop since adolescents are learning how to deal with powerful emotions.
- Conditions
- Adolescent Development, Mental Health Issue, Lifestyle Factors
- Trial name
- GENESIS (NCT07485673)
- Testing
- Observational
- Where
- Ecuador
- Volunteers
- 1,450 people, healthy volunteers welcome
- Sponsor
- Universidad de Especialidades Espiritu Santo
Psychological Distress
Practice-Based Evidence in Psychotherapy: A Multicentric Study From Ecuador
The goal of this observational study is to learn about the progress and outcomes of clients receiving psychotherapy for common mental health problems in Ecuador.
- Trial name
- CLIP_Ecuador (NCT07257848)
- Testing
- Psychological Intervention
- Where
- 11 sites in Ecuador
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Universidad de las Americas - Quito
Gingival Recession, Localized, Gingival Recession
Root Coverage With Tunneling Technique With Connective Tissue Versus Coronal Advancement Flap Technique.
This is a randomized triple-blind clinical trial. This comparative clinical study investigates the efficacy of root coverage using two periodontal techniques: the tunneling technique and the coronal advancement technique.
- Trial name
- NCT06228534
- Testing
- Root coverage with tunneling technique
- Where
- Ecuador
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Luis Alberto Chauca Bajaña
Alveolar Bone Resorption, Preserving the Alveolar Ridge
Radiographic Evaluation in Alveolar Preservation Using Platelet-rich Fibrin. Randomized Controlled Trial
This randomized controlled trial is designed to assess the use of platelet-rich fibrin (PRF), a biomaterial derived from a participant's own blood, in alveolar ridge preservation following premolar extraction for orthodontic…
- Trial name
- NCT06900036
- Testing
- Platelet-Rich Fibrin (PRF) Application for Alveolar Preservation
- Where
- Ecuador
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Universidad Católica de Cuenca
Healthy
Effect of Xylitol-based Chewing Gums, Sugar-free and Sugared, on Salivary Flow and pH in Young Adults
This study was planned to evaluate the effects of xylitol-based chewing gums, sugar-free and sugared, on salivary flow and pH in young adults.
- Trial name
- NCT06370091
- Testing
- Gum of Xylitol, Gum of sugar free, Gum of sugar
- Where
- Ecuador
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Católica de Cuenca
Preeclampsia, Intrauterine Growth Restriction
sFlt1/PlGF and Planned Delivery to Prevent Preeclampsia at Term.
Preeclampsia (PE) affects ~5% of pregnancies. Although improved obstetrical care has significantly diminished associated maternal mortality, PE remains a leading cause of maternal morbidity and mortality in the world.
- Conditions
- Preeclampsia, Intrauterine Growth Restriction, Maternal Hypertension, Neonatal Outcome
- Trial name
- PE37 (NCT04766866)
- Testing
- sFlt1/PlGF screening in maternal blood at 35 to 36.6 weeks of gestation
- Where
- 21 sites in Belgium, Colombia and 7 more
- Volunteers
- 9,132 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Modified Free Gingival Graft , Connective Tissue Graft
Efficacy of the Modified Free Gingival Graft Technique
Gingival recessions can be defined as the exposure of the root surface after an apical migration of the gingival margin in relation to the cemento-enamel junction. Gingival recessions affect both younger and older populations.
- Trial name
- FGG (NCT06580821)
- Testing
- mucogingigval surgery
- Where
- Ecuador
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad de Especialidades Espiritu Santo
Growth Disorders, Malnutrition, Fetal
Evolutionary Nutrition Pilot: Enhancing Fetal Growth and Brain Development
Globally, 250 million children do not reach their developmental potential and 155 million are stunted, yet few population-based studies have examined the direct effects of nutrient deficiencies on early brain development.
- Conditions
- Growth Disorders, Malnutrition, Fetal, Stunting, Development; Delayed, Malnutrition
- Trial name
- NCT05242224
- Testing
- Evolutionary Nutrition Package
- Where
- Ecuador
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Alveolar Bone Loss
Effectiveness of Alveolar Bone Preservation in Alveoli With Infectious Process
Alveolar ridge preservation (ARP) is a surgical technique that aims to minimize the degree of dimensional changes following extraction.
- Trial name
- NCT06661863
- Testing
- alveolar ridge preservation with bioactive glass, alveolar ridge preservation with autologous bone
- Where
- Ecuador
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Universidad de Especialidades Espiritu Santo
Pregnancy
Evaluation of Telemedicine Medical Abortion Service in Ecuador
This research seeks to demonstrate that a telemedicine model for the provision of legal abortion services in Ecuador is safe, feasible and acceptable to users requesting a medication abortion and who are less than 12 weeks…
- Trial name
- NCT06270056
- Testing
- Misoprostol
- Where
- 3 sites in Ecuador
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Mental Health Wellness 1, Psychological Distress
Feasibility of Community Psychosocial Intervention for Women
The purpose of the current protocol is to describe a cluster randomized feasibility trial examining the integration of a scalable stress management intervention into Entre Nosotras ('among/between us'), a community-based…
- Conditions
- Mental Health Wellness 1, Psychological Distress, Coping Skills, Stress
- Trial name
- NCT05130944
- Testing
- Entre Nosotras, Doing What Matters in Times of Stress
- Where
- 2 sites in Ecuador, Panama
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Columbia University
Zika Virus, Zika Virus Infection
VRC 705: A Zika Virus DNA Vaccine in Healthy Adults and Adolescents
This was a multicenter, randomized study to evaluate the safety, immunogenicity, and efficacy of VRC-ZKADNA090-00-VP (Zika virus wildtype DNA vaccine) or placebo.
- Conditions
- Zika Virus, Zika Virus Infection, Virus Diseases, Flavivirus Infections
- Trial name
- DNA (NCT03110770)
- Testing
- VRC-ZKADNA090-00-VP, VRC-PBSPLA043-00-VP
- Where
- 17 sites in United States, Brazil and 7 more
- Volunteers
- 2,428 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)