Clinical trials: open to volunteers, in Ecuador
Peripheral Arterial Disease, Atherosclerosis of Extremities
Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to Address Residual Vascular Risk
The Low dose ColchicinE in pAtients with peripheral Artery DiseasE to address residual vascular Risk (LEADER-PAD) trial will evaluate if anti-inflammatory therapy with colchicine will reduce vascular events in patients with…
- Conditions
- Peripheral Arterial Disease, Atherosclerosis of Extremities, Inflammation
- Trial name
- LEADER-PAD (NCT04774159)
- Testing
- Colchicine 0.5 MG Oral Tablet
- Where
- 86 sites in United States, Australia and 8 more
- Volunteers
- 6,150 people
- Sponsor
- Population Health Research Institute
Periodontitis, Periodontal Disease
Photodynamic Therapy as an Adjunct in Periodontal Treatment
This study aims to evaluate the clinical effectiveness of antimicrobial photodynamic therapy (aPDT) as an adjunct to scaling and root planing (SRP) in the treatment of periodontitis.
- Trial name
- PDT-PERIO (NCT07633405)
- Testing
- Scaling and Root Planing, Antimicrobial Photodynamic Therapy
- Where
- Ecuador
- Volunteers
- 30 people
- Sponsor
- Universidad Catolica Santiago de Guayaquil
Venous Thromboembolism
Computerized Registry of Patients With Venous Thromboembolism (RIETE)
The Computerized Registry of Patients with Venous Thromboembolism (RIETE) is a multidisciplinary Project initiated in march 2001 and consisting in obtaining an extensive data registry of consecutive patients with venous…
- Trial name
- RIETE (NCT02832245)
- Where
- 305 sites in United States, Argentina and 27 more
- Volunteers
- 120,000 people
- Sponsor
- Manuel Monreal
Intraductal Papillary Mucinous Neoplasm of Pancreas, Pancreatic Neoplasms
Real-Time AI During Pancreatoscopy for Detection of Pancreatic Neoplasia
This prospective pilot study will evaluate the diagnostic performance of a previously validated artificial intelligence (AI) model when applied in real time during digital per-oral pancreatoscopy (POPS).
- Trial name
- NCT07809841
- Testing
- AIWorks-Cholangioscopy Real-Time Artificial Intelligence Model
- Where
- Ecuador
- Volunteers
- 60 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
High-risk Cardiac Patients
Registry Study for the Evaluation of High-risk Cardiac Patients by WILLEM AI-based ECG Platform
The WILLEM Registry is a large-scale, single-group, observational, registry study to collect continuous clinical evidence of Willem in real-world settings.
- Trial name
- WILLEMRegistry (NCT07333547)
- Testing
- Willem AI ECG assessment
- Where
- 5 sites in United States, Ecuador and 1 more
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- Idoven 1903 S.L.
Bone Substitutes, Alveolar Bone Grafting
Bone Augmentation Techniques in the Mandible Posterior Region
This study will compare three methods to rebuild lost bone in the back part of the lower jaw (posterior mandible) before dental implant placement.
- Trial name
- NCT06661447
- Testing
- Cortical Shell Bone Grafting
- Where
- Ecuador
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Universidad de Especialidades Espiritu Santo
Complete Edentulism
Clinical Performance and Quality of Life of 3D-Printed Complete Dentures Under Digital vs Hybrid Workflows: A Randomized Crossover Trial
This prospective randomized crossover clinical trial evaluates and compares the clinical performance and oral health-related quality of life (OHRQoL) of complete dentures fabricated through two additive manufacturing workflows …
- Trial name
- PRINT-DENT (NCT07626827)
- Testing
- Digital Workflow Complete Denture, Hybrid Workflow Complete Denture
- Where
- Ecuador
- Volunteers
- 20 people
- Sponsor
- Universidad de Especialidades Espiritu Santo
Acute Kidney Injury, Fluid Overload
Volume Removal Intolerance During Net Ultrafiltration in Acute Kidney Injury Patients
Acute kidney injury (AKI) is common in critically ill patients and is frequently associated with fluid overload, which can worsen clinical outcomes.
- Conditions
- Acute Kidney Injury, Fluid Overload, Fluid Overload in Dialysis Patients, Critical Illness
- Trial name
- VINKO (NCT07643597)
- Where
- 10 sites in Brazil, Chile and 5 more
- Volunteers
- 128 people
- Sponsor
- Hospital Las Higueras
Acute Respiratory Distress Syndrome
Effect of Continuous Prolonged Prone Position Versus Intermittent Daily Prone Position in ARDS
Prone position (placing the patient on his abdomen) has been shown to be an effective intervention to decrease mortality in adults connected to mechanical ventilation for moderate to severe Acute Respiratory Distress Syndrome…
- Trial name
- ePRONE (NCT06854627)
- Testing
- Daily prone position sessions, Prolonged prone position sessions
- Where
- 38 sites in Argentina, Chile and 4 more
- Volunteers
- 780 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Mental Health Literacy
Roots for Life Project: Strengthening Mental Health in School Communities
This pilot study, titled "Roots for Life Project: Strengthening Mental Health in School Communities", aims to evaluate the feasibility and preliminary effectiveness of a mental health literacy (MHL) intervention for teachers and…
- Trial name
- NCT07564635
- Testing
- Child Mental Health Literacy Program
- Where
- 3 sites in Chile, Ecuador
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universidad de Valparaiso
Alveolar Bone Loss, Tooth Extraction
Reduced Time Interval for Implant Placement After Extraction Socket Preservation Using the Vega Plus Implants
This randomized controlled clinical trial aims to evaluate whether reducing the healing interval for implant placement after extraction socket preservation improves clinical and radiographic outcomes compared with the…
- Trial name
- RIP-VEGA (NCT07484685)
- Testing
- Reduced time interval treatment protocol, Standard time interval treatment protocol
- Where
- Ecuador
- Volunteers
- 40 people
- Sponsor
- Universidad Catolica Santiago de Guayaquil
Pregnancy, Postpartum
Organ Dysfunction Score for Obstetric Patients
The goal of this observational study is to develop and evaluate an organ dysfunction score adapted to pregnancy and early puerperium (SOFA-OBS) that also incorporates a non-invasive tool to evaluate respiratory function (pulse…
- Conditions
- Pregnancy, Postpartum, Organ Dysfunction, Critical Care, Intensive Care
- Trial name
- SOFA-OBS (NCT07068022)
- Testing
- Organ dysfunction score adjusted to obstetric patients (SOFA-OBS)
- Where
- 18 sites in Argentina, Ecuador and 2 more
- Volunteers
- 130 people
- Sponsor
- Daniela Vasquez
Childhood Cancer Survivors
Lifestyle Medicine Adherence, Mental Wellbeing, and Quality of Life in Pediatric Oncology in Ecuador
Background: Advances in pediatric oncology have significantly improved survival rates; however, many children and adolescents with cancer experience persistent physical and psychological challenges that negatively affect their…
- Trial name
- NCT07490548
- Where
- 4 sites in Ecuador
- Volunteers
- 62 people
- Sponsor
- Universidad de Especialidades Espiritu Santo
Adolescent Development, Mental Health Issue
GENESIS Project: Generating Evidence on the Needs of Ecuadorian Adolescents
Background: Adolescence is a period of intensified emotional responses and occurs when mental health disorders commonly develop since adolescents are learning how to deal with powerful emotions.
- Conditions
- Adolescent Development, Mental Health Issue, Lifestyle Factors
- Trial name
- GENESIS (NCT07485673)
- Testing
- Observational
- Where
- Ecuador
- Volunteers
- 1,450 people, healthy volunteers welcome
- Sponsor
- Universidad de Especialidades Espiritu Santo
Dialysis, Critically Ill Acute Kidney Injury
Epidemiology and Processes of Care for Renal Replacement Therapy in Acute Kidney Injury in Latin America
This is an international, multicenter, observational study aimed at investigating acute kidney injury requiring renal replacement therapy (AKI-RRT) in Latin American countries.
- Conditions
- Dialysis, Critically Ill Acute Kidney Injury, Renal Replacement Therapy for Acute Kidney Injury in ICU, Acute Kidney Injury
- Trial name
- LATAM-AKID (NCT07262320)
- Where
- 15 sites in Bolivia, Brazil and 7 more
- Volunteers
- 1,000 people
- Sponsor
- University of Alabama at Birmingham
Bariatric Surgery
Effects of Respiratory Muscle Training in Post-bariatric Surgery Patients
Obesity is a health condition caused by excessive accumulation of body fat. This condition is linked to the development of chronic diseases and also places increased stress on the respiratory system, leading to respiratory…
- Trial name
- NCT07289958
- Testing
- Institutionalized therapeutic exercise, Inspiratory muscle training, simulated inspiratory muscle
- Where
- Ecuador
- Volunteers
- 52 people
- Sponsor
- University Ramon Llull
Achalasia, EGJ Outflow Obstruction
Safety and Efficacy of a Novel SpydrBlade Flexible Bipolar in POEM
Achalasia is an idiopathic motility disorder, primarily identified by the absence of esophageal peristalsis and the inability of the lower esophageal sphincter (LES) to relax properly.
- Trial name
- NCT07406945
- Testing
- SpydrBlade Flex
- Where
- 2 sites in Ecuador, Hong Kong
- Volunteers
- 73 people
- Sponsor
- Chinese University of Hong Kong
Psychological Distress
Practice-Based Evidence in Psychotherapy: A Multicentric Study From Ecuador
The goal of this observational study is to learn about the progress and outcomes of clients receiving psychotherapy for common mental health problems in Ecuador.
- Trial name
- CLIP_Ecuador (NCT07257848)
- Testing
- Psychological Intervention
- Where
- 11 sites in Ecuador
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Universidad de las Americas - Quito
Preeclampsia, Intrauterine Growth Restriction
sFlt1/PlGF and Planned Delivery to Prevent Preeclampsia at Term.
Preeclampsia (PE) affects ~5% of pregnancies. Although improved obstetrical care has significantly diminished associated maternal mortality, PE remains a leading cause of maternal morbidity and mortality in the world.
- Conditions
- Preeclampsia, Intrauterine Growth Restriction, Maternal Hypertension, Neonatal Outcome
- Trial name
- PE37 (NCT04766866)
- Testing
- sFlt1/PlGF screening in maternal blood at 35 to 36.6 weeks of gestation
- Where
- 21 sites in Belgium, Colombia and 7 more
- Volunteers
- 9,132 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Cancer, Pediatric Cancer
Impact of a Physical Activity Program on the Health-Related Quality of Life in Pediatric Cancer Patients
Physical activity is essential for the health and well-being of children and adolescents. However, those living with cancer often experience reduced physical activity levels, which negatively impact their functional capacity and…
- Trial name
- NCT06813950
- Testing
- Physical activity
- Where
- Ecuador
- Volunteers
- 80 people
- Sponsor
- Sociedad de Lucha Contra el Cáncer