Clinical trials: open to volunteers, in Egypt
Symptomatic Irreversible Pulpitis, Symptomatic Apical Periodontitis
Effect of Cryotherapeutic and Nanotherapeutic Sodium Hypochlorite on Post-Operative Endodontic Pain.
This randomized clinical trial aims to compare the effects of conventional, cryotherapeutic, and nanotherapeutic sodium hypochlorite solutions used as final root canal irrigants on postoperative pain and substance P levels.
- Trial name
- NCT07923669
- Testing
- Cryotherapeutic Sodium Hypochlorite Irrigation., Nanotherapeutic Sodium Hypochlorite Irrigation
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- October 6 University
Airway Management
Tizanidine Premedication Versus Placebo for Laryngeal Mask Airway Insertion and Recovery in Adults Undergoing Ambulatory Surgery
This study will evaluate whether a single oral dose of tizanidine 4 mg given before surgery improves laryngeal mask airway (LMA) insertion conditions and postoperative recovery in adults undergoing elective ambulatory surgery…
- Trial name
- NCT07921602
- Testing
- Tizanidine
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Beni-Suef University
Sepsis
Effect of Rutin and Vitamin C on Outcomes in Adults With Sepsis Admitted to the Intensive Care Unit
The goal of this prospective, randomized, open-label, controlled clinical trial is to evaluate the efficacy and safety of rutin combined with vitamin C (Ruta C) and vitamin C alone as adjunctive therapies in adult patients aged…
- Trial name
- NCT07922213
- Testing
- Rutin plus Vitamin C, Vitamin C
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Ain Shams University
Chronic Kidney Disease and Hypertension
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
International, Multicenter, Double-Blind, Placebo-Controlled and Event-driven study to assess efficacy, safety and Tolerability of Baxdrostat in combination with Dapagliflozin on renal outcomes and cardiovascular mortality in…
- Trial name
- BaxDuo-Pacific (NCT06742723)
- Testing
- Baxdrostat/dapagliflozin
- Where
- 771 sites in United States, Argentina and 40 more
- Volunteers
- 5,000 people
- Sponsor
- AstraZeneca
Breast Cancer, Postoperative Pain
Effect of Pectoral Nerve Block (PECS) Using Magnesium Sulfate Added to Dexamethasone on Quality of Recovery and Chronic Post-Mastectomy Pain
This prospective, randomized, double-blind, controlled clinical trial will evaluate whether adding magnesium sulfate to dexamethasone-augmented ultrasound-guided pectoral nerve block improves postoperative recovery and analgesia…
- Conditions
- Breast Cancer, Postoperative Pain, Chronic Postoperative Pain, Quality of Recovery
- Trial name
- NCT07923643
- Testing
- Bupivacaine, Dexamethasone, Magnesium sulfate
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Colorectal Cancer
Nurse-Led Prehabilitation Before Major Abdominal Cancer Surgery
Many people who have major planned surgery for abdominal cancer develop complications afterwards, which can prolong hospital stay and slow recovery.
- Trial name
- NCT07922642
- Testing
- Nurse-Led Multimodal Prehabilitation Program
- Where
- Egypt
- Volunteers
- 104 people
- Sponsor
- Alexandria University
Probiotics, Antibiotics
Probiotics Versus Antibiotics as an Adjuvant to Non-surgical Periodontal Treatment Among Smokers With Stage II, Grade B Periodontitis
The aim of the present study is to evaluate and compare the clinical and biochemical effectiveness of systemic probiotics versus systemic antibiotics when used as adjuncts to nonsurgical periodontal treatment, scaling and root…
- Conditions
- Probiotics, Antibiotics, Adjuvant, Non-surgical
- Trial name
- NCT07923695
- Testing
- Vitacare, Vibramycin + Fasigyn, Non-surgical treatment modality
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- October 6 University
Ozone Gel, Chlorohexidine Gel
Ozone Gel Versus Chlorohexidine Gel as an Adjunct to Non-Surgical Treatment of Stage II Periodontitis Grade B Among Smokers Patients
The aim of the present study is to evaluate and compare the clinical and biochemical outcomes of Ozoral® and High Cure® (chlorhexidine gel) as adjuncts to non-surgical periodontal therapy in smoker patients with Stage II Grade B…
- Conditions
- Ozone Gel, Chlorohexidine Gel, Non-Surgical Treatment, Stage II Periodontitis
- Trial name
- NCT07923708
- Testing
- Conventional scaling and root planing, Conventional scaling and root planing in addition to chlorhexidine gel, Conventional scaling and root planing in addition to ozone gel
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- October 6 University
Postoperative Pain in Lumbar Spine Surgery
Adding Different Doses of Dexmedetomidine to Bupivecaine in Erector Spinae Plane Block
patients undergoing lumbar spine surgey are susciptible to severe pain , this study aim to examine if we add the substance dexmedetomidine to the local anethetic used in regional anthesia will be useful or not for those patients .
- Trial name
- NCT07923175
- Testing
- Erector spinae blane block with bupivecaine only, Erector spinae plane block using bupivecaine plus lower dose dexmedetomidine, Erector spinae plane block using bupivecaine plus higher dose of dexmedetomidine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mohamed Mahmoud Soliman
Alzheimer's Disease(AD), Mild Cognitive Impairment (MCI)
InRAD Observational Study
The goal of this international observational study is to evaluate long-term disease outcomes and treatment safety in people with Alzheimer's disease (PwAD), by collecting real-world data from routine clinical practice across…
- Conditions
- Alzheimer's Disease(AD), Mild Cognitive Impairment (MCI), Subjective Cognitive Decline (SCD), Non-Alzheimer Degenerative Dementia
- Trial name
- InRAD (NCT07213700)
- Testing
- None, this is a non-interventional observational study
- Where
- 23 sites in Australia, Austria and 15 more
- Volunteers
- 50,000 people
- Sponsor
- Stichting International Registry for Alzheimer's Disease and other Dementias Foundation
Seroma, Inguinal Hernias
Primary Sac Abandonment and Distal Sac Fixation vs Complete Sac Dissection for Inguinoscrotal Hernias
The goal of this clinical trial is to compare the effect of primary abandonment of the sac and distal sac fixation vs complete sac dissection in patients with inguinoscrotal hernias undergoing trans abdominal pre-peritoneal…
- Trial name
- NCT07918430
- Testing
- Primary abondonment of sac and distal sac fixation, complete sac dissection
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Gross Motor
The Hidden Burden of Cerebral Palsy: Exploring the Relationship Between Gross Motor Function of Children, Maternal Low Back Pain, and Quality of Life
Caregiving for cerebral palsy children covers a very wide range of activities such as heavy lifting and turning, bathing, helping the child to use the toilet, getting the child to sleep, dressing and assisting the transfer causes…
- Trial name
- cerebral palsy (NCT07919002)
- Testing
- gross motor group
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- October 6 University
Alveolar Bone Regeneration, Advanced Platelet-Rich Fibrin
Alveolar Bone Regeneration Using Advanced Platelet-Rich Fibrin Combined With Strontium-Doped Hydroxyapatite
This study aims to evaluate the effectiveness of advanced platelet-rich fibrin (A-PRF) combined with strontium-doped hydroxyapatite (Sr-HA) in enhancing alveolar bone regeneration following tooth extraction compared with…
- Conditions
- Alveolar Bone Regeneration, Advanced Platelet-Rich Fibrin, Strontium-Doped Hydroxyapatite
- Trial name
- NCT07918014
- Testing
- Advanced Platelet-Rich Fibrin, Advanced Platelet-Rich Fibrin combined with Strontium-Doped Hydroxyapatite, Heal spontaneously without placement of any grafting material
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Kafrelsheikh University
Acne, Acne Papulopustulosa
Evaluation of the Efficacy and Safety of Fractional CO₂ Laser With and Without Intradermal Botulinum Toxin A in the Treatment of Inflammatory Facial Acne Vulgaris.
The goal of this clinical trial is to learn if fractional CO₂ laser (FCO₂) with and without intradermal Botulinum Toxin A can treat inflammatory facial acne vulgaris in adult patients of both genders.
- Trial name
- NCT07919886
- Testing
- Fractional co2 laser, Botulinium Toxin-A
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Cairo University
Chronic Obstructive Pulmonary Disease (COPD), With Poitive H Pylori
Impact of Eradication Therapy on Helicobacter Pylori Infection With Chronic Obstructive Pulmonary Disease:
Helicobacter pylori (HP) is a well-established pathogen responsible for chronic gastritis and peptic ulcer disease. Its presence has been implicated in the development of gastric malignancies such as adenocarcinoma and…
- Trial name
- NCT07574879
- Testing
- Eradication of Helcobacter Pylori
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Zagazig University
Neuropathic Ulcers
Pulsed High Intensity Laser Versus Negative Pressure Therapy On Neuropathic Ulcers
the study comparess between laser therapy and vac to decide which on is superior
- Trial name
- VAC (NCT07557524)
- Testing
- Laser therapy, Negative pressure therapy is applied to the negative pressure group
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Pulpitis
Submucosal Cryotherapy and Anti-inflammatory Drugs for Postoperative Pain Following Root Canal Treatment in Maxillary Molars
Pain after root canal treatment is a common problem, particularly in teeth with symptomatic irreversible pulpitis, a condition involving severe inflammation of the tissue inside the tooth.
- Trial name
- NCT07919938
- Testing
- Articaine Hydrochloride With Epinephrine, Submucosal Cryotherapy, Diclofenac Sodium
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Suez Canal University
Borderline Personality Disorder (BPD)
Repetitive Transcranial Magnetic Stimulation Versus Theta Burst Stimulation on Impulsivity, Emotional Dysregulation, and Non-Suicidal Self-Injury in Borderline Personality Disorder Patients
the goal of this randomized clinical trial is to evaluate the therapeutic efficacy of repetitive transcranial magnetic stimulation (rTMS) and intermittent theta-burst stimulation (iTBS) in patients with borderline personality…
- Trial name
- TMS and TBS (NCT07919587)
- Testing
- Repetitive Transcranial Magnetic Stimulation, Intermittent Theta-Burst Stimulation
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Ain Shams University
Hemiplegic Cerebral Palsy
Effect of Robotic Gloves Training on Upper Limb Coordination, Selective Motor Control and Activities of Daily Living in Children With Hemiparetic Cerebral Palsy
The purposes of the current study will be to assess the effect of robotic gloves training on upper limb coordination, selective motor control (Wrist Extension/Flexion, Finger Flexion/Extension, Thumb Opposition (tip to tip…
- Trial name
- UL/SMC/ADL/CP (NCT07907497)
- Testing
- Robotic Glove Therapy, Occupational Therapy Group
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Spondyloarthropathy
Identification of Serum Level of Glutathione Peroxidase 4
Analysis of the level of glutathione peroxidase 4 (GPX4) in ankylosing spondylitis and axial psoriatic arthritis patients. The association of glutathione peroxidase 4 (GPX4) with disease activity and severity in ankylosing…
- Trial name
- NCT06554392
- Testing
- Blood sample
- Where
- Egypt
- Volunteers
- 85 people
- Sponsor
- Assiut University
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