Clinical trials: in Greece
Kidney Cancers, Prostate Cancer
Assessment of Intelligent Algorithms for Detection, Diagnosis and Risk Stratification of Tumors of the Kidney and Prostate
The COMFORT study will evaluate an artificial intelligence-based platform developed to support the clinical assessment of kidney and prostate cancer.
- Trial name
- COMFORT (NCT07888322)
- Testing
- Medical Reading, AI assisted Medical reading
- Where
- 6 sites in Germany, Greece and 2 more
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Endothelial Dysfunction, Acute Myocardial Infarction (AMI)
Validation of Cor-IS Impedance Spectroscopy Against Ultrasound Flow-Mediated Dilation
This prospective observational study evaluated the Cor-IS bioelectrical impedance spectroscopy technique for the assessment of endothelial function by comparison with ultrasound-based brachial artery flow-mediated dilation (FMD).
- Conditions
- Endothelial Dysfunction, Acute Myocardial Infarction (AMI), Cardiovascular Risk Factors (e.g., Hypertension), Flow Mediated Dilation
- Trial name
- NCT07882550
- Testing
- Cor-IS FMD, Ultrasound FMD
- Where
- Greece
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Coronary Artery Stenosis
Breathing-Maneuver-Induced Myocardial Oxygenation Reserve Validated by FFR (B-MORE)
The study aims to determine a diagnostic marker for regionally impaired myocardial oxygenation response in patients with suspected coronary artery stenosis.
- Trial name
- B-MORE (NCT04126148)
- Where
- 8 sites in United States, Australia and 5 more
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Matthias Friedrich
Hematologic Malignancy
Early Detection and Screening of Hematological Malignancies - SANGUINE
This is a multicenter, open-label, non-interventional controlled study to identify and characterize the epigenetic signatures for a set of hematological malignancies: Multiple myeloma (MM), pre-MM conditions [smoldering MM (SMM)…
- Trial name
- SANGUINE (NCT05735704)
- Testing
- Blood sampling for HemaChip screening/diagnostic testing
- Where
- 4 sites in Czechia, Greece and 2 more
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- JaxBio Ltd
Athletic Performance
Sideritis Supplementation and Performance
The purpose of this study is to examine the effect of sideritis consumption on physiological and performance indicators in adult subjects and compare it with the control trial.
- Trial name
- NCT07555288
- Testing
- 950 mg of Sideritis Scardica (SidTea+) extract one hour pre-exercise
- Where
- Greece
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
C3 Glomerulopathy (C3G), Healthy Adult Participants
A Clinical Trial to Test the Safety, Tolerability, and How the Body Processes CPV-104 in Healthy People and Patients With C3-Glomerulopathy
This study is the first time the new medicine CPV-104 is being tested in people. CPV-104 is designed to regulate the complement system, which can be overactive in diseases such as C3 glomerulopathy (C3G), an ultra-rare kidney…
- Trial name
- Essential One (NCT07483827)
- Testing
- CPV-104
- Where
- 17 sites in Austria, Belgium and 10 more
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- eleva GmbH
Clinical High Risk for Psychosis (CHR), Clinical High Risk for Psychosis
Stratification and Treatment in Early Psychosis Study - PROMOTE
The purpose of this trial is: To investigate whether cannabidiol (CBD), compared to placebo, can reduce the severity of attenuated psychotic symptoms in individuals at clinical high risk for psychosis.
- Conditions
- Clinical High Risk for Psychosis (CHR), Clinical High Risk for Psychosis, Clinical High Risk for Developing Psychosis
- Trial name
- STEP-PROMOTE (NCT07434973)
- Testing
- Cannabidiol (CBD)
- Where
- 19 sites in Austria, Canada and 8 more
- Volunteers
- 586 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Exercise Training Adaptation
Physiological and Molecular Adaptations to Different Training Modalities in National-level Kayak Athletes
This interventional study evaluated physiological, molecular, and performance adaptations to different high-intensity training modalities in national-level kayak athletes.
- Trial name
- NCT07864012
- Testing
- High-Intensity Interval Training, Sprint Interval Training, Combined High-Intensity and Continuous Training
- Where
- Greece
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Physical Disability, Intellectual Impairment
HIIT Versus High-Volume Training in Competitive Para Swimmers
This study compared the effects of four weeks of reduced-volume high-intensity interval training and higher-volume moderate-intensity swimming training on repeated-sprint ability, physiological responses, and body composition in…
- Conditions
- Physical Disability, Intellectual Impairment, Athletic Performance, Exercise Training
- Trial name
- NCT07862036
- Testing
- Reduced-Volume High-Intensity Interval Swimming Training, Higher-Volume Moderate-Intensity Swimming Training
- Where
- Greece
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Ovarian Cancer
Innovative Ovarian Cancer Biomarker Assays
Ovarian cancer is often diagnosed at a later stage because early symptoms can be mild or non-specific. Earlier detection of ovarian cancer could improve treatment options and outcomes.
- Trial name
- DISARM CSB (NCT07693894)
- Testing
- Investigational ovarian cancer biomarker assays
- Where
- 7 sites in Czechia, Greece and 3 more
- Volunteers
- 2,080 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Ulcerative Colitis (UC)
Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis
The Phase 1 study described herein will evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of XmAb942 in healthy volunteers (Parts A and B).
- Trial name
- NCT06619990
- Testing
- XmAb942
- Where
- 98 sites in United States, Argentina and 13 more
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Xencor, Inc.
Ovarian Cancer
CanRisk-Based Ovarian Cancer Risk Assessment Versus Standard Practice (DISARM CSA)
The purpose of this study is to improve how the risk of developing ovarian cancer is assessed in people who may be at increased risk of ovarian cancer due to their family history or genetic background.
- Trial name
- DISARM CSA (NCT07809659)
- Testing
- CanRisk, Standard clinical risk assessment
- Where
- 6 sites in Czechia, Greece and 2 more
- Volunteers
- 2,130 people, healthy volunteers welcome
- Sponsor
- Instituto Portugues Oncologia de Lisboa Francisco Gentil
Chronic Low-back Pain (cLBP)
Pain Assessment Through Integrated Neurophysiology and Multidimensional Profiling
This observational case-control study aims to investigate the central neurophysiological mechanisms underlying non-specific chronic low back pain (CLBP) with neural mechanosensitivity, with wearable Optically Pumped Magnetometers…
- Trial name
- PAIN-MAP (NCT07846163)
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Silent Cerebral Infarct, Biomarkers / Blood
Biomarkers as Prognostic Factors of Silent, Cerebral Infarctions in Patients Undergoing High-thromboembolic-risk Transcatheter Interventions
Background: The transcatheter interventions with high thromboembolic risk, as transcatheter carotid angioplasty or transcatheter ablation of cardiac arrhythmias are associated with asymptomatic strokes- silent strokes.
- Conditions
- Silent Cerebral Infarct, Biomarkers / Blood, Cardiac Ablation, Cognitive Impairment
- Trial name
- PRINCESS (NCT07844850)
- Testing
- High-thromboembolic-risk transcatheter interventions
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Guidelines, Diabetes Mellitus Type 2
Adherence to Clinical Guidelines for Management of Patients With Type 2 Diabetes Mellitus and Obesity
Observational study in physicians regarding their adherence to clinical guidelines (by American Diabetes Association 2025) for the management of type 2 diabetes mellitus and obesity via questionnaire
- Conditions
- Guidelines, Diabetes Mellitus Type 2, Obesity Type 2 Diabetes Mellitus, Obesity (BMI > 35) and Diabetes Mellitus
- Trial name
- NCT07839546
- Testing
- Questionnaire regarding the adherence to American Diabetes Association
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Thyroid Cancer, Thyroidectomy With Central Lymph Node Dissection
Does Parathyroid Autofluorescence Reduces Unintensional Parathyroidectomy During Total Thyroidectomy With Central Lymph Node Compartment Dissection
The aim of the study is to evaluate the effectiveness of autofluorescence in the intraoperative preservation of parathyroids during total thyroidectomy with central lymph node compartment dissection.
- Trial name
- FLUOBCC (NCT04339478)
- Where
- 2 sites in Greece, Jordan
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Multiple Sclerosis, Cognitive Decline
MS-NEUROPLAST: Neuroplasticity of Cortical Areas Induced by Cognitive Training in Patients With Multiple Sclerosis
This clinical study aims to identify MS related beneficial plasticity and by contrast maladaptive reorganization in combination with elements of daily functional status as a response to a cognitive training program
- Trial name
- MSNEUROPLAST (NCT04806568)
- Testing
- Cognitive Training, Monitoring of daily activity
- Where
- Greece
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Periapical Periodontitis, Endodontic Microsurgery
Healing After Endodontic Microsurgery Using a Rotary Bur Versus Piezoelectric Unit for Osteotomy and Root Resection
The goal of this clinical trial is to compare bone healing after using apical tooth microsurgery to remove root end infection, either by use of rotary burs for cutting bone and root end, or by use of piezoelectric surgery for the…
- Conditions
- Periapical Periodontitis, Endodontic Microsurgery, Osteotomy
- Trial name
- BURVSPIEZO (NCT07197658)
- Testing
- endodontic microsurgery / rotary bur osteotomy, Endodontic microsurgery / piezo osteotomy, Endodontic microsurgery / bone window
- Where
- 2 sites in Greece
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Diabetes Technology, Continuous Glucose Monitoring System
Healthcare Practitioners Knowledge on Diabetes Technology
Assessment of knowledge of healthcare professionals of diabetes mellitus technology (continuous glucose monitoring systems and insulin pump therapy).
- Conditions
- Diabetes Technology, Continuous Glucose Monitoring System, Continuous Insulin Infusion System, Insulin Pump Therapy
- Trial name
- NCT07822945
- Testing
- Questionnaire assessing knowledge on diabetes technology
- Where
- Greece
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Respiratory Syncytial Virus Infection Prevention, Tuberculosis Prevention
rBCG-N-RSV Vaccine in Adults Aged 60 Years and Older
This Phase 2 clinical study will evaluate the safety of the rBCG-N-RSV vaccine compared to conventional BCG in adults older than 60 years.
- Trial name
- NCT07762014
- Testing
- Vaccination with rBCG-N-RSV, Vaccination with conventional BCG (BCG-WT)
- Where
- Greece
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Biothervax SpA