Clinical trials: in Hong Kong
3-nil Buildings Seniors
Pilot Project on Enhancing Support for Hidden Elderly in the Three-nil Buildings and Old Tenement Buildings: Capacity Building & Impact Evaluation
The aims of this interventional study are of two-fold. First, the study aims to develop the capacity to facilitate the collaborating NGOs to address the social determinants of aging well for 3-N seniors.
- Trial name
- NCT07920328
- Testing
- Mapped intervention based on health status
- Where
- Hong Kong
- Volunteers
- 1,520 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Acute Heart Failure (AHF)
Comprehensive Clinical Prediction Rule for Acute Heart Failure
The goal of this prospective observational cohort study is to establish a comprehensive clinical prediction rule integrating clinical characteristics, point-of-care testing (POCT) of NT-proBNP, an 8-point LUS, and a rapid cardiac…
- Trial name
- NCT07754084
- Testing
- Acute Heart Failure Diagnostic Method
- Where
- 3 sites in Hong Kong
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Mitral Valve Insufficiency
Multi-center Study of Three-Dimensional Transesophageal Echocardiography in Patients With Secondary Mitral Regurgitation
Three-dimensional transesophageal echocardiography (3D-TEE) enables detailed assessment of mitral valve anatomy, annular geometry, and regurgitation.
- Trial name
- SMR-3DTEE (NCT07918937)
- Testing
- Transthoracic and Three-Dimensional Transesophageal Echocardiography
- Where
- 93 sites in China, Hong Kong and 1 more
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- First Hospital of China Medical University
Behavior
A Chatbot to Reduce Chemsex and HIV-related Risk Behaviors Among Men Who Have Sex With Men
The goal of this clinical trial is to investigate whether receiving chatbot-delivered stage-of-change-tailored online interventions is effective in reducing chemsex among men who have sex with men in Hong Kong.
- Trial name
- NCT07472582
- Testing
- Chatbot-delivered online interventions and online videos, Online videos only
- Where
- Hong Kong
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Dementia Caregiver
The Existential Cognitive Intervention to Enhance Positive Aspect of Caregiving (EXCITE-PAC) in a Dementia Context
Research evidence is emerging on the co-existence of a positive caregiving experience in the physically and psychosocially taxing dementia care context, but little attention has been paid to promoting the positive aspects of…
- Trial name
- EXCITE-PAC (NCT07396298)
- Testing
- Existential-cognitive intervention to enhance PAC, Usual care
- Where
- Hong Kong
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Sleep Disturbance, Emotional Disturbance
Pilot Trial for Health Products on Mood and Sleep Quality
This is a pilot, single-site clinical trial that will follow a randomized, double-blinded, parallel-group, placebo-controlled design.
- Trial name
- NCT06579183
- Testing
- Vita Calm Mood Booster Formula (VCMBF), Vita Calm Deep Sleep Formula (VCDSF)
- Where
- Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Prostate Cancer, PSA
MRI Prostate for Chinese Men Being Screened for Prostate Cancer
Under the prostate cancer screening protocol of the project 'Prevention of Obesity-related Cancers', men with elevated PSA with higher prostate cancer risk (PSA 4-10 ng/mL with high Prostate Health Index (PHI) ≥35, or PSA>10…
- Conditions
- Prostate Cancer, PSA, MRI
- Trial name
- NCT03891732
- Testing
- MRI prostate
- Where
- 2 sites in Hong Kong
- Volunteers
- 445 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Prostate Cancer
Artificial Intelligence (AI)-Assisted Risk-based Prostate Cancer Detection
This is a prospective clinical study recruiting 510 men at risk of PCa to undergo urine, blood, AI-assisted ultrasound and AI-assisted MRI investigations to stratify risk of clinically significant PCa (csPCa).
- Trial name
- NCT05443412
- Testing
- Diagnostic test for prostate cancer
- Where
- Hong Kong
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Ageing Well
An Effectiveness Evaluation for Pathway to Healthy Aging (Path-HA) Care on Health Status of Older Adults
The goal of this clinical trial is to provide a scientific evaluation on the effects of a protocol-driven Pathway to Healthy Aging (Path-HA) Program on promoting the health-related quality of life and functional abilities of…
- Trial name
- NCT06105723
- Testing
- Pathway to Healthy Aging care
- Where
- Hong Kong
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Atherosclerosis Cardiovascular Disease
Isometric Resistance Exercise on Accelerated Atherosclerosis in Hypertension
Background: Hypertension (HT) is the most common condition worldwide, predisposing to atherosclerotic disease. However, most HT patients have suboptimal BP control despite anti-HT medications.
- Trial name
- IRE-HT (NCT07665034)
- Testing
- Squatting Exercise, Stretching (Yoga) Exercise
- Where
- Hong Kong
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Fatty Pancreas, Microbiome Analysis
Microbiome Characterization in Fatty Pancreas
There has been a growing interest in evaluating the role of gut and intra-lesional microbiome in the pathogenesis of various benign and malignant conditions of the GI tract, liver and pancreas.
- Trial name
- FPM1 (NCT06938646)
- Where
- Hong Kong
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Amblyopia
Optical Correction and Visual Functions of Adults With Amblyopia
Amblyopia is a developmental anomaly resulting from abnormal visual experiences in early life. Amblyopia causes reduced visual acuity in the absence of a pathology.
- Trial name
- SPECTRA (NCT05394987)
- Testing
- Spectacles
- Where
- 2 sites in Canada, Hong Kong
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Centre for Eye and Vision Research
Pancreatic Steatosis, Pancreatic Cyst
Determination of Pancreatic Steatosis Prevalence and Correlation With High-risk Cyst Features
Pancreatic cancer is the fifth leading cause of cancer mortality in Hong Kong and the seventh leading cause of cancer mortality worldwide. In 2020, approximately 496000 new cases of pancreatic cancers were diagnosed globally .
- Trial name
- FPPCN (NCT05334836)
- Testing
- MRI for pancreatic fat and liver fat quantitation
- Where
- Hong Kong
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Nasopharyngeal Carcinoma
Prospective Nasopharyngeal Carcinoma Screening Using Plasma Epstein-Barr Virus DNA Analysis
The purpose of this study is to determine if the screening of nasopharyngeal carcinoma using plasma Epstein-Barr virus DNA analysis would result in the detecting NPC cases at earlier stages and improve survival.
- Trial name
- NCT02063399
- Where
- Hong Kong
- Volunteers
- 20,302 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Fertility Awareness, Ovarian Reserve
Improving Women's Fertility Awareness and Reducing Anxiety Through Ovarian Reserve Screening and AI Counseling
This study evaluates the impact of preventive ovarian reserve screening and artificial intelligence (AI)-enabled counseling on fertility awareness and reproductive anxiety among women in Hong Kong.
- Conditions
- Fertility Awareness, Ovarian Reserve, Family Planning
- Trial name
- NCT07894302
- Testing
- AI-Enabled Fertility Counseling, Standard Educational Materials or PDF laboratory reports
- Where
- Hong Kong
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- City University of Hong Kong
Gastric Lesion, Gastritis
Capsule Gastric Endoscopy for Gastric Disease Screening in Simulated Home Scenarios
The goal of this clinical trial is to evaluate the diagnostic accuracy of the AI-integrated Capsule Gastroscopy (ACG) system in simulated home-use conditions for detecting upper gastrointestinal (UGI) abnormalities.
- Conditions
- Gastric Lesion, Gastritis, Upper Gastrointestinal Bleeding (UGIB), Gastric Dysplasia
- Trial name
- NCT06848400
- Testing
- AI-integrated Capsule Gastroscopy (ACG) examination, Electronic gastroduodenoscopy (EGD) examination
- Where
- 12 sites in China, Hong Kong and 1 more
- Volunteers
- 482 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
COVID-19 Infection
Integrated Mindfulness-based Health Qigong Intervention for COVID-19 Survivors and Caregivers
This study examines the effectiveness of a 16-week Integrated Mindfulness-based Health Qigong (iMBHQ) program, delivered via a mobile application, in improving the mental and physical well-being of COVID-19 survivors, their…
- Trial name
- NCT06194357
- Testing
- Mindfulness-based Health Qigong Intervention
- Where
- 2 sites in Hong Kong
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- TSANG Hector Wing-Hong
Obstructive Sleep Apnea
Mucosal Inflammation in Children With OSA
Objectives: Variability of clinical phenotypes in childhood obstructive sleep apnoea (OSA) has prompted research for biomarkers to identify patients at risk of developing OSA-related complications.
- Trial name
- NCT06452979
- Where
- Hong Kong
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Multiple Sclerosis
Intravoxel Incoherent Motion (IVIM) Magnetic Resonance Imaging in Multiple Sclerosis
Intravoxel incoherent motion (IVIM) is technique based on diffusion-weighted imaging (DWI). In this study, the investigators evaluate the use of IVIM in patients with Multiple Sclerosis.
- Trial name
- NCT05391906
- Testing
- Diffusion-weighted magnetic resonance imaging
- Where
- Hong Kong
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Psychological Wellness
Resilient Students Training (ReST) : A Pilot RCT
Resilience is the ability to survive and thrive despite significant adversity. Trials of resilience-promoting interventions for university students have shown significant improvements in students' resilience and reductions in…
- Trial name
- ReST (NCT06157931)
- Testing
- Resilient Student Training intervention (ReST)
- Where
- Hong Kong
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University