Clinical trials: in Iceland
Pancreas Cancer, Pancreas Cyst
Pancreatic Cancer Early Detection Consortium
The purpose of the Pancreatic Cancer Early Detection (PRECEDE) Consortium is to conduct research on multiple aspects of early detection and prevention of pancreatic ductal adenocarcinoma (PDAC) by establishing a multisite cohort…
- Conditions
- Pancreas Cancer, Pancreas Cyst, Pancreatic Ductal Adenocarcinoma, Genetic Predisposition
- Trial name
- PRECEDE (NCT04970056)
- Where
- 62 sites in United States, Australia and 10 more
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Arbor Research Collaborative for Health
Respiratory Infections
Omega-Cold Supplementation With Free Fatty Acids for the Prevention of Respiratory Infections in Adults.
The purpose of this study is to investigate whether fish oil containing free fatty acids affects people's susceptibility to viral infections such as colds, influenza, and COVID-19, as well as the course of these illnesses.
- Trial name
- OmegaCold FFA (NCT07314593)
- Testing
- Omega-3 oil with 2% Free Fatty Acids, Vegatable oil
- Where
- Iceland
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Landspitali University Hospital
Breast Cancer, Circadian Rhythms
The Effects of Light Therapy to Treat Cancer-related Side Effects
Severe fatigue, depression, sleep problems and cognitive impairment are the most commonly reported side effects of cancer treatment.
- Conditions
- Breast Cancer, Circadian Rhythms, Fatigue, Sleep Disturbance
- Trial name
- NCT04418856
- Testing
- Light Glasses (Experimental), Light Glasses (Comparison)
- Where
- Iceland
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Reykjavik University
Intrusive Memories of Traumatic Event(s)
The Lóa Study: A Brief Digital Intervention for Women With Intrusive Memories in the SAGA Cohort
Intrusive memories are sensory memories of a traumatic event(s) that spring to mind involuntarily, and can evoke strong emotions and disrupt functioning in daily life.
- Trial name
- NCT05849337
- Testing
- Brief imagery-competing task, Brief psychoeducation and signposting task, Treatment as usual (TAU)
- Where
- Iceland
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- University of Iceland
Frailty in Adult Surgery, Frailty Syndrome
Modified Essential Frailty Toolset in Older Adults Undergoing Major Elective Surgery
Frailty is a common geriatric syndrome associated with reduced physiological reserve and increased vulnerability to surgical stress.
- Conditions
- Frailty in Adult Surgery, Frailty Syndrome, Elective Surgeries, Readmission Rates
- Trial name
- NCT07452263
- Testing
- Major elective surgery
- Where
- Iceland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Iceland
Side Effect of Drug
NORTH-REG Dwell-Time Study
Previous studies show that the majority NMIBC patients experience side effects to BCG and therefore terminate the instillations before completing all planned instillations.
- Trial name
- NCT04701151
- Testing
- Bacillus Calmette Guerin
- Where
- 11 sites in Denmark, Iceland and 1 more
- Volunteers
- 314 people, healthy volunteers welcome
- Sponsor
- Jørgen Bjerggaard Jensen
Fall Prevention, Balance, Falls
Evaluating Methods to Replicate Stumbles and Slips During Walking
This protocol outlines a study designed to investigate three different methodologies for inducing gait perturbations. Subjects will be divided into two groups: prosthetic users and able-bodied individuals.
- Conditions
- Fall Prevention, Balance, Falls, Amputation of Lower Limb
- Trial name
- NCT07175714
- Testing
- Methodologies to induce gait perturbations
- Where
- 2 sites in Iceland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Össur Iceland ehf
Frailty in Adult Surgery, Frailty Syndrome
Validity of Frailty Screening Tools as a Measure for Postoperative Outcomes
Frailty is a common geriatric syndrome defined as a clinical state of decreased physiologic reserve resulting in increased vulnerability to stressors.
- Conditions
- Frailty in Adult Surgery, Frailty Syndrome, Elective Surgery
- Trial name
- NCT07367828
- Testing
- Intermediate/major elective surgery
- Where
- Iceland
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University of Iceland
Immune Responses, Antibiotic Treatment
The Effects of Antibiotic Exposure in Early Infancy on Vaccine Responses
This prospective cohort study will include 200 term children born in Landspitali University Hospital in Iceland. The cohort will be divided into four groups according to antibiotic exposure of which one is the control group.
- Trial name
- NCT06079606
- Testing
- Antibiotic treatment
- Where
- Iceland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Landspitali University Hospital
Monoclonal Gammopathy of Undetermined Significance
Iceland Screens, Treats or Prevents Multiple Myeloma
This study will assess the benefits and harms of screening for monoclonal gammopathy of undetermined significance (MGUS). The overall and disease-specific mortality will be compared between screened and not screened participants.
- Trial name
- iStopMM (NCT03327597)
- Testing
- Clinical follow-up 1, Mental Health and Quality of Life questionnaire, Standard follow-up or treatment.
- Where
- Iceland
- Volunteers
- 80,761 people, healthy volunteers welcome
- Sponsor
- University of Iceland
Surgical Scars
Evaluation of the Scar Healing Effects of ChitoCare Medical Scar Healing Gel in Women Undergoing Breast Reduction or Mastopexy Surgery (CHITOSCAR)
Patients undergoing breast reduction or mastopexy surgery will be screened and recruited for participation in the study. Eligible patients will act as their own control with one breast receiving the active intervention…
- Trial name
- CHITOSCAR (NCT06992960)
- Testing
- ChitoCare® medical Scar Healing Gel (Örsáragel), Amoena CuraScar Mammilla Circles Silicone Scar Patch and Amoena CuraScar Anchors Silicone Scar Patch
- Where
- Iceland
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Primex ehf
Parkinson Disease
Retinal Biomarkers in Parkinson´s Disease
The goal of this observational study is to determine whether oxygen content of the retinal vessels of the eye may serve as a biomarker in Parkinson´s disease. The main questions it aims to answer are: 1.
- Trial name
- NCT06929026
- Where
- Iceland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Landspitali University Hospital
Sleep Quality
Sleep Quality and the Menstrual Cycle
This study aims to examine how ovarian hormone fluctuations across the menstrual cycle affect sleep patterns. Using objective sleep tracking, hormone phase assessment, and validated questionnaires, it will assess changes in sleep…
- Trial name
- NCT06906133
- Testing
- Urinary-hCG
- Where
- 2 sites in Iceland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Akureyri
Sleep, Depression
Behavioral and Sleep Hygiene Education With Mindfulness Intervention to Improve Sleep Regularity in Adolescents
Sleep plays a fundamental role in both mental- and physical-health, with good sleep health including adequate duration and quality, appropriate timing, regularity, and absence of sleep disorders.
- Conditions
- Sleep, Depression, Anxiety, Chronotype
- Trial name
- NCT06028997
- Testing
- Behavioral and Sleep Hygiene Education with Mindfulness Intervention
- Where
- 2 sites in Iceland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Solveig Magnusdottir
Obesity, Lifestyle
MicroFIBERgut: Effects of Lifestyle Changes and Chitosan on Gut Microbiota and Weight Management
The purpose of this study is to compare the effects of chitosan diet supplementation to a placebo supplement on changes in gut microbiota, body weight and different health parameters among different population groups, being…
- Trial name
- NCT04551365
- Testing
- Lifestyle changes, Chitosan
- Where
- Iceland
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Iceland
Attention-deficit Hyperactivity
Cognitive Behavioral Therapy for University Students Diagnosed With Attention-deficit Hyperactivity Disorder (ADHD)
Drug treatment is often the first and only line of treatment available for ADHD. However, some do not benefit from medication. The importance of psychotherapy is becoming more widely accepted.
- Trial name
- NCT04714866
- Testing
- Cognitive behavioral therapy for ADHD
- Where
- Iceland
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Iceland
Sleep Disturbance, Depression
The Effects of Bright Light Therapy on Adolescent's Sleep Quality and Well-being
Sleep problems are common among adolescents which can have a variety of serious biological, emotional, cognitive and psychological consequences.
- Conditions
- Sleep Disturbance, Depression, Mood, Circadian Rhythms
- Trial name
- NCT05555186
- Testing
- BWL classrooms (Experimental), DWL classrooms (Comparison)
- Where
- Iceland
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Reykjavik University
Punch Biopsy Wounds, Healing Times
Healing of Punch Graft Wounds. Comparative Study Between MariGen and Oasis: a Non-inferiority Study
The objective is to determine, if healing of punch biopsy wounds treated with the fish skin derived MariGen Wound dressing is non-inferior to healing with wounds treated with pig intestines derived Oasis Sheet wound dressing.
- Trial name
- NCT01917591
- Testing
- Punch biopsies treated with MariGen Wound ECM dressing, Punch biopsies treated with Oasis ECM dressing
- Where
- Iceland
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Kerecis Ltd.
Injuries
Incidence of Acute Injuries in Boxing
A prospective cohort study with 9 months follow up was carried out in 2017-2018. Boxers of both sexes 18 years and older from all 7 boxing clubs in Iceland were invited to participate in the study.
- Trial name
- NCT06264323
- Where
- Iceland
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Iceland
Oppositional Defiant Disorder
Emotion Regulation as a Moderator of Two Different Treatments for Children With ODD
The goal of this randomized controlled trial is to is to test emotion regulation as a moderator of two different treatments for children with Oppositional Defiant Disorder (ODD).
- Trial name
- NCT06194994
- Testing
- Parent Management Training, Tuning Your Temper
- Where
- Iceland
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- University of Iceland