Clinical trials: in Martinique
Prostate Cancer
CHLORDECONE EXPOSURE AND PROSTATE CANCER IN THE FRENCH REGION OF MARTINIIQUE
Prostate cancer is the most common male cancer in industrialized countries, including France, with over 60,000 new cases each year, and represents the third leading cause of cancer-related death in men.
- Trial name
- CHLOECAPA (NCT06773806)
- Where
- 2 sites in Martinique
- Volunteers
- 3,600 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
HIV Prevention
Dat'Aids Prevention
DatAIDS prevention is a cohort study of HIV prevention in over 23 HIV sites in France including overseas, aiming to describe HIV prevention in every aspect including HIV screening, STI and hepatitis screening, post-exposure…
- Trial name
- NCT03795376
- Where
- 31 sites in France, Guadeloupe and 1 more
- Volunteers
- 6,500 people, healthy volunteers welcome
- Sponsor
- DatAids
Incidence of ZIKV Infection on Fetus During the Pregnancy
Zika Virus Infection's Pregnancy Consequences in French Department of America
The Zika (ZIKV) epidemic has spread into the three French Overseas Departments in the Caribbean (DFAs). It is therefore urgent to set up tools to collect clinical and paraclinical data for the evaluation of potential…
- Trial name
- ZIKA-DFA-FE (NCT02916732)
- Where
- 4 sites in French Guiana, Guadeloupe and 1 more
- Volunteers
- 26,980 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Oncologic Diseases, Cancer
Analysis of the Determinants of the Participation of Patients and Health Professionals of the University Hospital Center of Martinique in Clinical Research Protocols in Medical Oncology (StudyOrec)
For optimal patient care, it is imperative that healthcare professionals implement appropriate strategies. These strategies must take into account changes in healthcare practices associated with advances in medications and…
- Conditions
- Oncologic Diseases, Cancer, Oncology
- Trial name
- NCT07206927
- Testing
- Qualitative Study: Semi-structured interview for patients, Quantitative Study : Healthcare professionals questionnaires
- Where
- Martinique
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital Center of Martinique
HCV, Substance Use Disorders
Community Intervention to Eliminate HCV Among People Who Use Drugs.
The goal of this interventional study is twofold with the evaluation of the feasibility and potential usefulness of an implementation strategy, and the efficiency of a community-based model of mass screening and immediate…
- Trial name
- ICONE2 (NCT05794646)
- Testing
- Hybrid effectiveness-implementation study type 2
- Where
- 4 sites in France, Martinique
- Volunteers
- 3,400 people, healthy volunteers welcome
- Sponsor
- ANRS, Emerging Infectious Diseases
Metastatic Colorectal Cancer
FOLFOX + Panitumumab According to a "Stop and go" Strategy With a Reintroduction Loop After Progression on Fluoropyrimidine as Maintenance Treatment, as the First Line in Patients With Metastatic Colorectal Adenocarcinoma Without a RAS Mutation
Single-arm, multi-centre phase II study The primary objective is to evaluate the time to failure of the strategy.
- Trial name
- OPTIPRIME (NCT03584711)
- Testing
- FOLFOX + panitumumab
- Where
- 124 sites in France, Martinique
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Federation Francophone de Cancerologie Digestive
Weight Gain, Weight Loss
Weight Changes Among Martinican Prisoners
Assessment of body weight change among prisoners in Martinique between admission in jail and 3 months later expressed as a percentage of admission weight.
- Trial name
- NUTRI-LAJÔL (NCT05982132)
- Testing
- anthropometric measurement
- Where
- Martinique
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- University Hospital Center of Martinique
Suicide, Mental Disorders
Contribution of Psychological Autopsy to the Understanding of Suicidal Behaviors in French Overseas Territories
The mains objectives of our project are to coordinate the monitoring of suicides and to identify common or specific suicide risk factors in four overseas DROM-COM (French Polynesia, La Reunion, French Guiana and Martinique) by…
- Conditions
- Suicide, Mental Disorders, Prognostic Factors
- Trial name
- AUTOPSOM (NCT05773898)
- Testing
- other
- Where
- Martinique
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital Center of Martinique
Cancer
Prioritising Prevention of COVID-19 in Persons With Cancer in the French West Indies
The public health council (Haut Conseil de Santé Publique) published a statement on 14 March 2020 relating to the management of patients with severe forms of COVID-19, stipulating specific recommendations for patients with…
- Trial name
- RESILIENCE (NCT04768153)
- Testing
- Serology
- Where
- Martinique
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University Hospital Center of Martinique
Psychological Trauma, Posttraumatic Stress Disorder PTSD
Psychometric and Patholinguistic Assessment of Psychotrauma Related to Natural Hazards in the Commune of "Le Prêcheur"
The project is to study the evolution of mental health in a little town of the French Martinique (Le Prêcheur) by using an innovative method of analysis that combines patholinguistic and psychometric indications for patients who…
- Conditions
- Psychological Trauma, Posttraumatic Stress Disorder PTSD, Mass Casualty Incidents
- Trial name
- EP3LAN (NCT04479670)
- Where
- Martinique
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University Hospital Center of Martinique
Blood Donors, Dengue
Dengue Seroprevalence Study in Blood Donors in the French West Indies
Dengue is an infectious disease most prevalent in the world. This disease is endemic in the Caribbean, with an increase in seasonal rains.
- Trial name
- DengSeroprevAn (NCT01104740)
- Testing
- Biological sample collection
- Where
- 2 sites in Guadeloupe, Martinique
- Volunteers
- 817 people, healthy volunteers welcome
- Sponsor
- Etablissement Français du Sang, Martinique
Brain Ischemia
Cerebral Perfusion Associated With Postural Changes: an ASL MR Perfusion Study
Postural changes are commonly used as therapeutic maneuver to enhance or reduce cerebral perfusion. For instance, in acute stroke, the patient can be positioned in head down tilt position so as to increase perfusion of cerebral…
- Trial name
- PerfIRMAVC (NCT02912546)
- Testing
- MRI
- Where
- Martinique
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University Hospital Center of Martinique
Postoperative Pulmonary Complications
Respiratory Variability for Respiratory Monitoring During the Postoperative Recovery Period
The research consist of measuring respiratory variability of several variables of the respiratory pattern at rest and during exercise using a thoracic movement measuring technique.
- Trial name
- VariaRessPi (NCT04605250)
- Testing
- Respiratory variability before and after surgery
- Where
- Martinique
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital Center of Martinique
Chikungunya Virus Infection
Trial for Safety and Immunogenicity of a Chikungunya Vaccine, VRC-CHKVLP059-00-VP, in Healthy Adults
This is a multicenter, randomized, placebo-controlled, double-blind study to evaluate the safety and immunogenicity of a 2-injection vaccine Chikungunya virus (CHIKV) virus-like particle vaccine (CHIKV VLP) in healthy adults.
- Trial name
- NCT02562482
- Testing
- VRC-CHKVLP059-00-VP, VRC-PBSPLA043-00-VP
- Where
- 6 sites in Dominican Republic, Guadeloupe and 3 more
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Multiple Myeloma
Multiple Myeloma and Environmental Exposure to Pesticides in the French West Indies: A Population Based Case-control Study.
Multiple myeloma (MM) is a malignancy of plasma cells engaging in monoclonal immunoglobulin production. A strong presumption was established between exposure to pesticides and the risk of MM.
- Trial name
- MYELODOM (NCT04260490)
- Where
- 2 sites in Guadeloupe, Martinique
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Guadeloupe
Alzheimer's Disease
Alzheimer's Disease and Physiological, Cognitive Function and BDNF Levels of Plasma Adaptation After Exercise Training
Alzheimer's disease (AD) is a neurodegenerative disease leading to one of the most common forms of dementia in humans and memory disorder is one of the first symptoms that lead to diagnosis.
- Trial name
- MARAE (NCT02968875)
- Testing
- Endurance Training, therapeutic education meetings
- Where
- Martinique
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University Hospital Center of Martinique
HTLV-I Infections
Influence of IL28B Genetic Variation on the Phenotype Infection of HTLV-1
Only 5 to 10% of patients infected with HTLV-1 develop a disease related to infection. The two most serious diseases are adult T-cell leukemia (ATL) and Tropical spastic paraparesis /HTLV-I-associated myelopathy (TSP / HAM).
- Trial name
- HAMIL28B (NCT01754311)
- Where
- 2 sites in Martinique
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- University Hospital Center of Martinique
Atypical Parkinsonism
Epidemiology and Pathophysiology of Parkinsonism in the Caribbeans
The primary aim of this study is to estimate the frequency and to characterize clinically atypical parkinsonism in the French West Indies and Guyana.
- Trial name
- CAP (NCT03368300)
- Testing
- Clinical and biological exam
- Where
- 2 sites in French Guiana, Martinique
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Guadeloupe
Unexplained Isolated Provoked Hemorrhages, Familial Bleeding Disorder
Markers of Defective Membrane Remodelling in Scott-like Syndromes
Purpose: Identification of the gene(s) involved in plasma membrane remodelling. Identification of the circulating markers affected by the defective membrane remodelling in a collection of families with unexplained provoked…
- Conditions
- Unexplained Isolated Provoked Hemorrhages, Familial Bleeding Disorder, Scott Syndrome
- Trial name
- NCT00617721
- Testing
- Blood withdrawal
- Where
- 5 sites in France, Martinique
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Rheumatoid Arthritis
Study of Human Leukocyte Antigen (HLA) Polymorphisms in Patients With Rheumatoid Arthritis
Rheumatoid arthritis (RA), affects between 0.3% and 1.0% of the population, it can lead to progressive joint destruction and severe disability.
- Trial name
- HLAPRPA (NCT01111357)
- Testing
- Collect of 10 ml of peripheric blood for DNA extraction
- Where
- Martinique
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital Center of Martinique