Clinical trials: completed, in Monaco
Frail Elderly
Long-term Effects of Interventional Strategies to Prevent Cognitive Decline in Elderly.
The MAPT PLUS study is a two-year extension of follow-up of the patients included in the MAPT preventive study, after completion of the interventions. Subjects in the four groups of the MAPT study will be prospectively followed.
- Trial name
- MAPT-PLUS (NCT01513252)
- Testing
- Gröber and Buschke test
- Where
- 13 sites in France, Monaco
- Volunteers
- 1,028 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Alzheimer's Dementia (AD), Family Caregivers
Long-term Follow-up of Patients Included in the EYE-TAR(MA) Study.
EYE-TAR(MA)-Follow-Up is a non-interventionel, long-term follow-up study in subjects who participated to the study referred as EYE-TAR(MA) (NCT04730440) EYE-TAR(MA)-Follow-Up aims to evaluate the long-term impacts of the Training…
- Trial name
- NCT05254873
- Testing
- Long term follow-up
- Where
- Monaco
- Volunteers
- 7 people
- Sponsor
- Association de Recherche Bibliographique pour les Neurosciences
Brain Injuries, Concussion, Brain
The Monaco Initiative for Concussion in Motorsport Pilots
The study aims: to observe a population particularly exposed by the past to brain trauma and concussion: Motorsport Pilots who are retired from a professional practice of motor sport; to report results of their neuro-cognitive…
- Conditions
- Brain Injuries, Concussion, Brain, Sport Injury
- Trial name
- NCT04730167
- Testing
- Neurological and neuropsychological assessments / MRI / PET scan / Video-oculography.
- Where
- Monaco
- Volunteers
- 12 people
- Sponsor
- Association de Recherche Bibliographique pour les Neurosciences
End Stage Renal Failure on Dialysis
ALdosterone Antagonist Chronic HEModialysis Interventional Survival Trial
This study is designed to etablish the effects of spironolactone in comparison to placebo on the composite endpoint of nonfatal Myocardial Infarction (MI) and acute coronary syndrome, hospitalization for heart failure, nonfatal…
- Trial name
- ALCHEMIST (NCT01848639)
- Testing
- Spironolactone
- Where
- 70 sites in Belgium, France and 1 more
- Volunteers
- 823 people
- Sponsor
- University Hospital, Brest
Lung; Nodule, Liver Metastases
Study of Different Gating Techniques for PET Image of Lung and Liver Lesions
Lesions blurred by respiratory motion are common in fluorine-18 PET/CT studies. To avoid these artefacts, several standard gating correction technics are available.
- Trial name
- PETGATQUANT (NCT05779865)
- Where
- Monaco
- Volunteers
- 29 people
- Sponsor
- Centre Hospitalier Princesse Grace
Head and Neck Squamous Cell Carcinoma
Non Inferiority Trial of Standard RT Versus Hypofractionated Split Course in Elderly Vulnerable Patients With HNSCC
Randomized comparison between standard radiotherapy and hypofractionated split course schedule. Compared to standard radiotherapy, the investigators expect that hypofractionated split course (interruption of 2 weeks) radiotherapy…
- Trial name
- ELAN-RT (NCT01864850)
- Testing
- Standard RT, Hypofractionated RT
- Where
- 2 sites in France, Monaco
- Volunteers
- 202 people
- Sponsor
- Groupe Oncologie Radiotherapie Tete et Cou
Infection, Sepsis
Early Identification of SEPsis SIGNs in Emergency Department
Objective of SepSIGN project is to validate biomarkers able to predict the clinical worsening of patients freshly admitted at Emergency Department.
- Trial name
- SepSIGN (NCT04261621)
- Where
- 12 sites in United States, France and 1 more
- Volunteers
- 815 people
- Sponsor
- BioMérieux
Alzheimer's Dementia (AD), Family Caregivers
Rehabilitation of Facial Emotion Recognition in Alzheimer's Disease
EYE-TAR(AD+) is an observational study based on the same design as the princeps EYE-TAR(MA) study, but with a larger number of patients and including an additional evaluation of Facial emotion recognition (based on a more…
- Trial name
- NCT05267028
- Testing
- AD-TAR, AD-Cognitive Stimulation
- Where
- Monaco
- Volunteers
- 16 people
- Sponsor
- Association de Recherche Bibliographique pour les Neurosciences
COVID19, Oxygen Therapy
Impact of Prone Position in Patients Under Spontaneous Breathing on Intubation or Non-invasive Ventilation or Death Incidence During COVID-19 Acute Respiratory Distress
The SARS-Cov2 viral pandemic is responsible for a new infectious disease called COVID-19 (CoronaVIrus Disease), is a major health problem.
- Conditions
- COVID19, Oxygen Therapy, Prone Position, Spontaneous Ventilation
- Trial name
- PROVID-19 (NCT04363463)
- Testing
- prone position
- Where
- 19 sites in France, Monaco
- Volunteers
- 268 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Ovarian Cancer
Platine, Avastin and OLAparib in 1st Line
Randomized, Double-Blind, Phase III Trial of Olaparib vs. Placebo in Patients with Advanced FIGO Stage IIIB - IV High Grade Serous or Endometrioid Ovarian, Fallopian Tube, or Peritoneal Cancer treated with standard First-Line…
- Trial name
- PAOLA-1 (NCT02477644)
- Testing
- Olaparib
- Where
- 163 sites in Austria, Belgium and 9 more
- Volunteers
- 806 people
- Sponsor
- Arcagy Research
Healthy
Eye Movements Recording Using a Smartphone: Comparison to Standard Video-oculography and Correlation to Imaging Data in Young Athletes
This study aims to compare measurements obtained through the e-VOG application (mobile application, usable on smartphones or tablets, to record eye movements) with measurements from the standard video-oculography device…
- Trial name
- NCT05385601
- Testing
- eVOG (Mobile VideoOculoGraphy)
- Where
- Monaco
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Association de Recherche Bibliographique pour les Neurosciences
Healthy
Eye Movements Recording Using a Mobile : Comparison to Standard Video-oculography in Young Athletes
This study aims to compare measurements obtained through the e-VOG application (mobile application, usable on smartphones or tablets, to measure eye movements) with measurements from the standard video-oculography device…
- Trial name
- e-VOG(YA) (NCT05211752)
- Testing
- eVOG (Mobile VideoOculoGraphy)
- Where
- Monaco
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Association de Recherche Bibliographique pour les Neurosciences
Depression
SMTr-METAB : FDG-PET Assessment of Cerebral Metabolism in Resistant Depression Treated With rTMS
Biological markers of depressive states have been studied, but their usefulness to predict the therapeutic response is unknown. This issue is major in all depressive states which have not remitted after several lines of…
- Trial name
- SMTr-METAB (NCT02754375)
- Testing
- rTMS
- Where
- 2 sites in France, Monaco
- Volunteers
- 22 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Sepsis
Diagnostic Performance of a New Bio-marker During Bacterial Sepsis
Sepsis is a constant concern in ICU, frequent and severe, it requires early diagnosis and prompt implementation of the etiological treatment.
- Trial name
- BACTIDIAG (NCT02721134)
- Testing
- additional blood tubes
- Where
- 6 sites in France, Monaco
- Volunteers
- 450 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
SARS-CoV-2 Infection
Microvascular Injury and Distal Thrombosis in COVID-19
Investigators aimed to better understand the pathophysiology of SARS-CoV-2 pneumonia in non-critically ill hospitalized patients secondarily presenting with clinical deterioration and increase in oxygen requirement
- Trial name
- MIND (NCT04990505)
- Testing
- lung ventilation/perfusion scintigraphy
- Where
- Monaco
- Volunteers
- 25 people
- Sponsor
- Centre Hospitalier Princesse Grace
Alzheimer Dementia, Parkinson Disease
Assessment of Empathetic Process by Scanpath Study of an Artwork
Analysis of gaze patterns during social cognition tasks and standardised exploration of a specific artwork, between elderly subjects without cognitive disorders and subjects with neurodegenerative diseases such as Fronto-Temporal…
- Conditions
- Alzheimer Dementia, Parkinson Disease, Fronto-Temporal Dementia
- Trial name
- EYE-EMPATH (NCT04665622)
- Testing
- Eye-Tracking / Neuropsychological evaluations
- Where
- Monaco
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Princesse Grace
Multiple Sclerosis
Eye Movements Recording Using a Smartphone: Comparison to Standard Video-oculography in Patients With Multiple Sclerosis
This study aims to compare measurements obtained through the e-VOG application (mobile application, usable on mobile phones or tablets, to measure eye movements) with measurements from the standard video-oculography device…
- Trial name
- NCT04702763
- Testing
- Eye-Tracker®T2 + e-VOG, e-VOG + Eye-Tracker®T2
- Where
- Monaco
- Volunteers
- 30 people
- Sponsor
- Association de Recherche Bibliographique pour les Neurosciences
Rheumatoid Arthritis
Long-term Experience With Abatacept SC in Routine Clinical Practice
The purpose of this study is to estimate the retention rate of Abatacept SC over 24 months in routine clinical practice, in rheumatoid arthritis patients, in each country involved in the study.
- Trial name
- ASCORE (NCT02090556)
- Where
- 12 sites in Australia, Austria and 9 more
- Volunteers
- 2,954 people
- Sponsor
- Bristol-Myers Squibb
Rheumatoid Arthritis
Vaccination Against Pneumococcal in Naïve Abatacept Rheumatoid Arthritis Patients
Is pneumococcal conjugate vaccine (which induces a T-dependent humoral response) more efficient than pneumococcal polysaccharide vaccine (which induces a T-independent humoral response) in RA patients treated with abatacept…
- Trial name
- VACINA (NCT02547493)
- Testing
- pneumococcal polysaccharide vaccine, pneumococcal conjugate vaccine, Abatacept
- Where
- 11 sites in France, Monaco
- Volunteers
- 80 people
- Sponsor
- University Hospital, Montpellier
Hyperthyroidism
Thyroid Uptake Quantification on a New Generation of Gamma Camera
The primary objective of this study is to evaluate the potential of a new large field CZT gamma camera to estimate the thyroid uptake (TU) on Single photon emission computed tomography (SPECT) and SPECT/CT images in comparison…
- Trial name
- QUANTHYC (NCT05049551)
- Where
- Monaco
- Volunteers
- 23 people
- Sponsor
- Centre Hospitalier Princesse Grace