Clinical trials: in Morocco
Sickle Cell Disease
A Study of IMR-687 in Subjects With Sickle Cell Disease
A Study to Evaluate the Safety and Efficacy of IMR-687 in Subjects with Sickle Cell Disease
- Trial name
- NCT04474314
- Testing
- IMR-687
- Where
- 49 sites in United States, Ghana and 11 more
- Volunteers
- 115 people
- Sponsor
- Cardurion Pharmaceuticals, Inc.
Fluid Responsiveness
Plethysmographic Perfusion Index and Fluid Responsiveness
The objective of this study is to assess the reliability of the perfusion index to predict fluid responsiveness in patients with acute circulatory failure in intensive care.
- Trial name
- PPI-FR (NCT06313671)
- Testing
- Perfusion index
- Where
- Morocco
- Volunteers
- 50 people
- Sponsor
- Avicenna Military Hospital
Hemodialysis, Self-care
Educational Program for Patients Undergoing Hemodialysis.
This study aims to evaluate the impact of an educational intervention on improving knowledge, self-care practices, and treatment adherence among hemodialysis patients at the Youssoufia Hemodialysis Center, located in the…
- Conditions
- Hemodialysis, Self-care, End Stage Renal Disease
- Trial name
- EDU-HD (NCT06642090)
- Testing
- Educational intervention for patients undergoing hemodialysis in Morocco
- Where
- Morocco
- Volunteers
- 70 people
- Sponsor
- Cadi Ayyad University
Multiple Sclerosis
Efficacy, Safety and Pharmacokinetics of Teriflunomide in Pediatric Patients With Relapsing Forms of Multiple Sclerosis
Primary Objective: To assess the effect of teriflunomide in comparison to placebo on disease activity measured by time to first clinical relapse after randomization in children and adolescents 10 to 17 years of age with relapsing…
- Trial name
- TERIKIDS (NCT02201108)
- Testing
- Teriflunomide
- Where
- 57 sites in United States, Belgium and 20 more
- Volunteers
- 166 people
- Sponsor
- Genzyme, a Sanofi Company
Adhesive Capsulitis of the Shoulder
Effectiveness of Instrumental Rehabilitation in Patients With Adhesive Capsulitis
The aim of this study is to evaluate the effectiveness of robotic training compared to conventional rehabilitation in patients with AC.
- Trial name
- NCT06766448
- Testing
- robotic training, conventionnal rehabilitation
- Where
- Morocco
- Volunteers
- 70 people
- Sponsor
- Mohammed V Souissi University
Arterial Hypertension
Hypertension Registry: Study of Primary and Secondary Hypertension Phenotypes, Complications, and Treatment Personalization.
The quality of primary healthcare systems for patients with hypertension (HTA) in Morocco is a critical issue due to its high prevalence and significant impact on morbidity and mortality.
- Trial name
- NCT06769269
- Where
- 5 sites in Morocco
- Volunteers
- 10,000 people
- Sponsor
- Moroccan Society of Cardiology
Carcinoma, Non-Small-Cell Lung
A Study of Atezolizumab (Tecentriq) to Investigate Long-term Safety and Efficacy in Previously-treated Participants With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC)
This is a Phase III/IV, single-arm, multicenter study of the long-term safety and efficacy of atezolizumab treatment in participants with Stage IIIb or Stage IV NSCLC who have progressed after standard systemic chemotherapy…
- Trial name
- TAIL (NCT03285763)
- Testing
- Atezolizumab
- Where
- 111 sites in Argentina, Brazil and 22 more
- Volunteers
- 619 people
- Sponsor
- Hoffmann-La Roche
Medullary Thyroid Cancer
Predictive Factors for Medullary Thyroid Cancer Aggressiveness
This study is a retrospective study trying to find the predictive factors for medullary thyroid aggressiveness in terms of tumor metastasis and patients' survival.
- Trial name
- MYELO (NCT06292988)
- Testing
- Total Thyroidectomy
- Where
- 46 sites in United States, Austria and 22 more
- Volunteers
- 500 people
- Sponsor
- Aristotle University Of Thessaloniki
Non-Hodgkin Lymphoma
Safety Study of Rituximab (SC) Administered in Participants With CD20+ DLBCL or CD20+ Follicular NHL Grade 1 to 3A
This open-label, single-arm study will evaluate the safety of rituximab subcutaneously (SC) administered during first line treatment for follicular non-Hodgkin's lymphoma (NHL) (Induction and/or Maintenance treatment plus 24…
- Trial name
- NCT02406092
- Testing
- Rituximab, Cyclophosphamide, Doxorubicin
- Where
- 13 sites in Algeria, Morocco and 1 more
- Volunteers
- 139 people
- Sponsor
- Hoffmann-La Roche
Preload-responsiveness
Is Mitral Velocity Time-integral a Marker of Preload-responsiveness in Patients With Acute Circulatory Failure?
The aim of this is to assess the reliability of the variability of the mitral velocity time-integral with passive leg raising to predict the fluid responsiveness in patients with acute circulatory failure in intensive care.
- Trial name
- NCT05538637
- Testing
- Echocardiography
- Where
- Morocco
- Volunteers
- 50 people
- Sponsor
- Avicenna Military Hospital
Atrial Fibrillation, Atrial Fibrillation (Prevention of Stroke)
Registry Initiative Across Borders for Atrial Fibrillation in Africa
Atrial fibrillation is a penalizing disease in several ways: morbidity and mortality, health costs. Several multicenter registries have been published.
- Conditions
- Atrial Fibrillation, Atrial Fibrillation (Prevention of Stroke), ATRIAL FIBRILLATION, Syncope
- Trial name
- RIBATAFRICA-AF (NCT06674304)
- Where
- Morocco
- Volunteers
- 3,000 people
- Sponsor
- Mohammed VI University Hospital
Arthritis, Rheumatoid
A Study To Describe The Use Of Tofacitinib After Use Of Rituximab In Patients With Rheumatoid Arthritis In A Real-World Setting
This study is to characterize the use of tofacitinib after use of rituximab in patients with Rheumatoid Arthritis in a real-world setting.
- Trial name
- NCT05487703
- Where
- Morocco
- Volunteers
- 318 people
- Sponsor
- Pfizer
Pulmonary Aspergillosis, Surgery-Complications
Uniportal VATS Resection for Pulmonary Aspergilloma : Evaluation of Prognostic Factors in a Single Center Experience
The objective of this study was to report our experience with U-VATS resection and to evaluate our surgical outcomes with an analysis of postoperative complications.
- Conditions
- Pulmonary Aspergillosis, Surgery-Complications, Thoracic Diseases
- Trial name
- NCT06564727
- Testing
- Uniportal VATS approach, VATS approach
- Where
- Morocco
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Hassan II University
Anemia of Chronic Kidney Disease
Oral Liposomal Iron Versus Injectable Iron Sucrose for Anemia Treatment in Non-Dialysis Chronic Kidney Disease Patients
This study aims to assess the comparative effects of intravenous and liposomal oral iron on hemoglobin levels in non-dialysis CKD patients.
- Trial name
- NCT06556134
- Testing
- Intravenous Iron Sucrose, Oral Iron
- Where
- Morocco
- Volunteers
- 27 people
- Sponsor
- Centre Hospitalier Hassan II - Fès
Healthy
Empowering Adolescents to Lead Change Using Health Data
This study is a cluster randomized trial carried out in schools of secondary cities of four low- and middle income countries. Baseline surveys in 30 randomly selected schools will assess the health behaviours of 13-17 year old…
- Trial name
- NCT04963426
- Testing
- Behavioral interventions targeting multiple risk behaviors as well as protective factors, School-level interventions targeting the school environment and system
- Where
- 5 sites in Ghana, India and 3 more
- Volunteers
- 12,612 people
- Sponsor
- World Health Organization
Anesthesia, Spinal, Cesarean Section
Abdominal Circumference Measure in Caesarian Section
The goal of this observational study is to evaluate preoperative measures of abdominal circumference in patients admitted for a cesarean section.
- Trial name
- ACirCuS (NCT06357637)
- Testing
- Measure of abdominal circumference
- Where
- Morocco
- Volunteers
- 124 people
- Sponsor
- CHU Mohammed VI Marrakech
Autism Spectrum Disorder
Smartphone-Based Neurobehavioral Assessments as a Diagnostic Aid in Autism
Retrospective case-control study to assess the diagnostic accuracy in autism spectrum disorder (ASD) of a new smartphone-based platform designed to conduct neurometric evaluations by measuring facial and behavioural reflexes.
- Trial name
- NCT06497218
- Testing
- Blinklab diagnostic device
- Where
- Morocco
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Blinklab Limited
Metastatic Renal Cell Carcinoma
Real-world Clinical Patterns Of Care And Outcomes Among AfME mRCC Patients Receiving Sunitinib as First Line Therapy.
OPTIMISE is designed to provide knowledge regarding the use of Sunitinib as 1st line treatment and 2nd line treatment selected (Sunitinib-different sequence) with respect to efficacy outcomes, adverse events, and health related…
- Trial name
- OPTIMISE (NCT03140176)
- Testing
- Sunitinib
- Where
- 8 sites in Algeria, Egypt and 2 more
- Volunteers
- 77 people
- Sponsor
- Pfizer
Triple-Negative Breast Cancer
A Study of Atezolizumab and Paclitaxel Versus Placebo and Paclitaxel in Participants With Previously Untreated Locally Advanced or Metastatic Triple Negative Breast Cancer (TNBC)
This Phase 3, multicenter, randomized, double-blind, placebo controlled study is designed to evaluate the efficacy and safety of atezolizumab (MPDL3280A, an anti-programmed death-ligand 1 [PD-L1] antibody) administered in…
- Trial name
- IMpassion131 (NCT03125902)
- Testing
- Atezolizumab (MPDL3280A), an engineered anti-PDL1 antibody, Paclitaxel
- Where
- 161 sites in United States, Argentina and 22 more
- Volunteers
- 653 people
- Sponsor
- Hoffmann-La Roche
Gap co2, Cardiac Output, Low
Gap CO2 in Septic Patient to Predict Cardiomyopathy Septic
the investigators included 98 patients admitted for sepsis and septic shock (68.4% men, 31.6% women) with an average age of 60.42 years ± 15.13, ranging from 21 to 96 years. The average length of hospital stay was 7.53 days.
- Conditions
- Gap co2, Cardiac Output, Low, Cardiac Defect
- Trial name
- NCT06326762
- Testing
- comparaison
- Where
- Morocco
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Mohammed VI University Hospital