Clinical trials: completed, in Pakistan
Ulcerative Colitis (UC)
Oral Vitamin D3 Effect on Inflammatory Biomarkers in Ulcerative Colitis Patients
This randomized controlled trial aims to evaluate the effect of oral vitamin D3 supplementation on inflammatory biomarkers and disease activity in Pakistani patients with moderate ulcerative colitis.
- Trial name
- OVDIEIBUCP (NCT07269223)
- Testing
- Vitamin D3
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Veterinary and Animal Sciences, Lahore - Pakistan
Neonatal Respiratory Distress Syndrome
Heated, Humidified High-flow Nasal (HHHFN) Cannula vs Nasal Continuous Positive Airway Pressure in Respiratory Distress in Premature Neonates
Newborn babies who have difficulty breathing may need breathing support to help them receive enough oxygen. Two commonly used methods are heated, humidified high-flow nasal cannula (HHFNC), which delivers warmed, moist air and…
- Trial name
- NCT07891494
- Testing
- Heated Humidified High-Flow Nasal Cannula therapy, nCPAP
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Pakistan Air Force (PAF) Hospital Islamabad
Cervicogenic Headache
Effects of Strain Counterstrain Versus Post Isometric Relaxation on Pain, Headache Frequency, and Quality of Life in Females With Cervicogenic Headache.
Cervicogenic headache is a secondary headache disorder associated with dysfunction of the cervical spine and surrounding muscles.
- Trial name
- SCS-PIR (NCT07897695)
- Testing
- Post Isometric Relaxation, Strain Counterstrain
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Qurat Ul Ain Ashfaq
Hearing Disorder
Genetic Analyses of Nonsyndromic and Syndromic Deafness in Pakistan
Objective: One objective of this study is to genetically map and identify mutated genes for human hereditary hearing loss. A second objective is to study the function of these genes in the auditory system using mouse models.
- Trial name
- NCT00341874
- Where
- Pakistan
- Volunteers
- 18,009 people
- Sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)
Hypertension, Primary Hypertension
Text Message Support to Help Adults With Newly Diagnosed High Blood Pressure Control Their Blood Pressure in Primary Care Clinics in Germany and Pakistan
The goal of this clinical trial is to learn if text messages can help adults with newly diagnosed high blood pressure (hypertension) bring their blood pressure under control.
- Trial name
- NCT07878728
- Testing
- mHealth Text Message Program, Usual Care
- Where
- Pakistan
- Volunteers
- 1,295 people
- Sponsor
- GIFT University
Recurrent Bacterial Vaginosis
Probiotics as an Adjunct to Antibiotics for Recurrent Bacterial Vaginosis
This randomized clinical trial aims to compare the recurrence of bacterial vaginosis (BV) in women receiving probiotics alongside antibiotic treatment versus women receiving antibiotic treatment alone.
- Trial name
- NCT07893782
- Testing
- Probiotic Combination Cap/Tab
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Nishtar Medical University
Identification of Residual Cholesteatoma After Microscopic Mastoidectomy With and Without Check Endocscopy
Comparison of Outcomes of Microscopic Mastoidectomy With and Without Check Endoscopy
PROJECT SUMMARY Cholesteatoma is a serious otological condition that remains a serious problem and poses a great challenge to otolaryngologists around the globe.
- Trial name
- NCT07896200
- Testing
- Mastoidectomy with and without check endoscopy for cholesteatoma surgery
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Sheikh Zayed Federal Postgraduate Medical Institute
Ventral Hernia Repair, Hernia Abdominal Wall
Onlay vs. Sublay Mesh Hernioplasty for Primary Ventral Hernia
This randomized controlled trial will compare the surgical outcomes of onlay mesh hernioplasty versus sublay mesh hernioplasty in patients with primary ventral wall hernias.
- Trial name
- NCT07896278
- Testing
- Onlay Mesh Hernioplasty, Sublay Mesh Hernioplasty
- Where
- Pakistan
- Volunteers
- 76 people
- Sponsor
- Provincial Headquarter Teaching Hospital Gilgit
Oral Submucous Fibrosis
Curcumin Plus Topical Steroid Versus Topical Steroid Alone for Oral Submucous Fibrosis
This study evaluates whether combining oral curcumin (a natural compound derived from turmeric) with a topical steroid is more effective than using a topical steroid alone in treating Oral Submucous Fibrosis (OSMF).
- Trial name
- NCT07891130
- Testing
- Curcumin and and triamcinolone acetonide, Triamcinolone Acetonide
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Liaquat College of Medicine and Dentistry
Knee Arthritis Osteoarthritis, Neuromuscular Adaptations
Effects Of Sensor Assisted Neuro-muscular Exercise Vs Electrical Stimulation On Bio-mechnical And Functional Parameters In Grade II And III Knee Osteoarthritis.
This two-arm randomized controlled trial compared Sensory-Assisted Neuromuscular Exercise (Group A) with Electrical Stimulation (Group B) in 40 adults aged 40-65 with Kellgren-Lawrence Grade II-III knee osteoarthritis, recruited…
- Trial name
- NCT07891351
- Testing
- Sensory-Assisted Neuromuscular Exercise, Electrical stimulation
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Ziauddin University
Liver Biomarkers, Glucose
Modulatory Effects of Resveratrol Supplement Along With and Without Low Glycemic Index Diet Among Obese Patients With Diabetic Nephropathy
This 12-week randomized controlled trial evaluated the effects of resveratrol supplementation with and without a low glycemic index (LGI) diet in obese patients with diabetic nephropathy.
- Conditions
- Liver Biomarkers, Glucose, Lipid Profiles
- Trial name
- NCT07891975
- Testing
- T0 starch capsule, T1 resveratrol capsule, T2 300 mg per day along with a low glycemic index diet, TWICE A DAY
- Where
- Pakistan
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Lahore
Generalised Anxiety Disorder, Anxiety
Effectiveness of Single-Session Acceptance and Commitment Therapy for Generalized Anxiety Symptoms.
This study examined whether a single 120-minute, therapist-led Acceptance and Commitment Therapy (SS-ACT) session, delivered individually and face-to-face in Urdu, was associated with reduced generalized anxiety symptoms among…
- Trial name
- SS-ACT (NCT07892768)
- Testing
- Single-Session Acceptance and Commitment Therapy (SS-ACT)
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- GIFT University
Exercise Activity
Effect of a 12-Week Aerobic Exercise Program on Cardiac, Respiratory, Metabolic Health and Functional Fitness in Healthy Young Adults
This randomized controlled trial evaluated the effects of a structured 12-week multicomponent exercise program with an aerobic emphasis on cardiovascular, respiratory, metabolic, and functional fitness outcomes in healthy…
- Trial name
- NCT07892781
- Testing
- Structured Multicomponent exercise intervention program
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Shaheed Zulfiqar Ali Bhutto Medical University
Chronic Hepatitis Delta Virus Infection
A Study to Assess Efficacy and Safety of HH-003 Injection in Subjects With Chronic Hepatitis Delta Virus Infection
This is a multicenter, randomized, controlled, open-label, Phase IIb study of HH-003 injection, HH-003 injection is a monoclonal antibody targeting Hepatitis B virus.
- Trial name
- NCT05861674
- Testing
- HH-003(20mg/kg), HH-003(10mg/kg), TAF
- Where
- 7 sites in China, Pakistan
- Volunteers
- 101 people
- Sponsor
- Huahui Health
Symptomatic Irreversible Pulpitis
Comparison of Postoperative Pain After Root Canal Irrigation in Symptomatic Irreversible Pulpitis
This randomized controlled trial will compare postoperative pain following root canal treatment in patients with symptomatic irreversible pulpitis.
- Trial name
- NCT07821359
- Testing
- Dexamethasone, Sodium Chloride 0.9%
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- CMH Lahore Medical College and Institute of Dentistry
Aphasia
Learning to Communicate Successfully Approach for Urdu Speaking Patients With Chronic Aphasia
This study aims to develop and validate the Learning to Communicate Successfully Approach (LCSA), a culturally sensitive communication intervention manual for Urdu-speaking adults with chronic aphasia.
- Trial name
- LCSA (NCT07889778)
- Testing
- Learning to Communicate Successfully Approach (LCSA)
- Where
- 2 sites in Pakistan
- Volunteers
- 30 people
- Sponsor
- University of Lahore
Stroke
Comparison of Exergaming Training With Visual Feedback Training on Upper Limb Functions in Post Stroke Patients
Stroke is classically characterized as a neurological deficit attributed to an acute focal injury of the central nervous system (CNS) by a vascular cause, including transient ischemic attack, cerebral infarction, intracerebral…
- Trial name
- NCT05673421
- Testing
- Exergaming Training, Visual Feedback Training
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Chronic Anal Fissure
Topical Nitroglycerin Versus Lateral Internal Sphincterotomy for Chronic Anal Fissure
Chronic anal fissure is a tear in the lining of the anal canal that can cause pain during and after defecation. This randomized controlled trial will compare topical 0.2% nitroglycerin ointment with lateral internal…
- Trial name
- NCT07884916
- Testing
- Topical 0.2% Glyceryl Trinitrate (Nitroglycerin) Ointment, Lateral Internal Sphincterotomy
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- Sheikh Zayed Federal Postgraduate Medical Institute
Pituitary Adenoma
Comparison of Extent of Resection of Pituitary Adenoma Via Transnasal Transsphenoidal Approach Using Endoscope Versus Microscope
This randomized controlled trial, titled "Comparison of Extent of Resection of Pituitary Adenoma via Transnasal Transsphenoidal Approach Using Endoscope Versus Microscope," was conducted in the Department of Neurosurgery, Sir…
- Trial name
- GTR MRI (NCT07886242)
- Testing
- Endoscopic surgery, Microscopic surgery
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Sir Ganga Ram Hospital
Suicide, Suicide Prevention
Suicide Prevention Integration Into Task-shifted Mental Health Interventions
Investigators will conduct a pilot clinical trial to assess the feasibility and acceptability of implementing a Suicide Prevention Package (SuPP) within an existing task-shifted depression intervention in rural Pakistan.
- Conditions
- Suicide, Suicide Prevention, Suicidal Ideation
- Trial name
- KPZ (NCT06208293)
- Testing
- KPZ Program (KPZ), Enhanced Usual Care (EUC)
- Where
- Pakistan
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Yale University