Clinical trials: in Reunion
Contraception Behavior
SAPLAI : Assessing the faiSAbility of a Peer-to-peer Contraceptive Education Program on Social Networks Aimed at 15- to 19-year-old High School Students in GuAdeloupe and La RéunIon
The goal of this clinical trial is to evaluate the feasibility of a contraception education program delivered by peers via social networks to high school students.
- Trial name
- SAPLAI (NCT06943209)
- Testing
- Creation of a contraception education program and post on social networks for high school students, Education program, Survey and questionnaires
- Where
- 2 sites in Guadeloupe, Reunion
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Non-cystic Fibrosis Bronchiectasis
Long-term Evaluation of the SIMEOX Device at Home in Non-cystic Fibrosis Bronchiectasis
Bronchiectasis is a chronic lung disease of multiple aetiologies characterised by permanent dilatation of the calibre of a territory of the bronchial tree with impaired mucociliary clearance.
- Trial name
- Home-BRAC (NCT06487273)
- Testing
- SIMEOX, Remote Physiotherapy
- Where
- 57 sites in France, Germany and 4 more
- Volunteers
- 622 people
- Sponsor
- Physio-Assist
Kidney Cancer
UroCCR Database: French Research Network for Kidney Cancer -UroCCR
Kidney cancer management has become increasingly complex with the diversification of treatment options and the integration of multidisciplinary care.
- Trial name
- UroCCR (NCT03293563)
- Testing
- Radical nephrectomy versus partial nephrectomy (according surgeon judgement)
- Where
- 68 sites in Belgium, France and 2 more
- Volunteers
- 30,000 people
- Sponsor
- University Hospital, Bordeaux
Post Extubation Respiratory Failure
Non-Invasive Ventilation Versus High-flow Nasal Oxygen in Intensive Care Units
In intensive care units (ICUs), around 20% of patients experience respiratory failure after planned extubation. Nearly 40-50% of them eventually require reintubation with subsequently high mortality rates reaching 30-40%.
- Trial name
- VENTILO (NCT05686850)
- Testing
- High-Flow Oxygen, Non invasive ventilation
- Where
- 47 sites in Belgium, France and 3 more
- Volunteers
- 670 people
- Sponsor
- Poitiers University Hospital
Cystic Fibrosis
Pathogenicity of Species of the Achromobacter Genus in Patients From Reunion Island With Cystic Fibrosis
The pathogenicity of Achromobacter bacteria is not yet well established, but studies show a decline in respiratory function and an increase in mortality associated with chronic colonisation, making it possible to classify the…
- Trial name
- ACHROMO-MUCO (NCT06371261)
- Testing
- Biological analyses
- Where
- 2 sites in Reunion
- Volunteers
- 17 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Pseudomonas Infections, Pseudomonas Aeruginosa
Antimicrobial Therapy for Difficult-to-treat Pseudomonas Aeruginosa
The primary objective of the ADDICT study is to assess and compare the clinical efficacy of available options for antimicrobial therapy (new beta-lactam/beta-lactamase inhibitor combination, cefiderocol or older agents such as…
- Conditions
- Pseudomonas Infections, Pseudomonas Aeruginosa, Prognosis, Drug Resistance, Multiple, Bacterial
- Trial name
- ADDICT (NCT06738771)
- Where
- 48 sites in France, Reunion
- Volunteers
- 600 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Esophageal Atresia
Long Term Outcome of Easophageal Atresia : Transmics Profiles in Adolescence
Oesophageal atresia (OAEA), a malformation of the oesophagus present from birth, is characterized by the interruption of the continuity of the oesophagus, which then ends in a cul-de-sac.
- Trial name
- TransEAsome (NCT05995171)
- Testing
- Questionnaire
- Where
- 33 sites in France, Martinique and 1 more
- Volunteers
- 300 people
- Sponsor
- University Hospital, Lille
Very Preterm Birth
EPIPAGE2 Cohort Study Follow up at Five and a Half Years
Epipage 2 (epidemiologic study on small-for-gestational-age children) is a nationwide study implemented to improve our knowledge of the outcome of preterm children in France.
- Trial name
- EPIPAGE2 (NCT03078439)
- Testing
- Medical and neuropsychological assessments
- Where
- 98 sites in France, French Guiana and 2 more
- Volunteers
- 3,404 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Appendicitis
Same Day Ambulatory Appendectomy (SAMBA)
The potential benefit of outpatient care for this common digestive emergency is considerable, both for the patients themselves and for the public health system: 1.
- Trial name
- SAMBA (NCT05691348)
- Testing
- Ambulatory appendectomy, Conventional appendectomy
- Where
- 33 sites in France, Reunion
- Volunteers
- 1,400 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
PreDiabetes
Impact of SMS Reminder on Weight Loss, as Part of a Health Pathway in Patients With Prediabetes (PREDIABCOACH)
The goal of this interventionnal study is to demonstrate that sending SMS messages with advice on physical activity or nutrition, in addition to a program of hygienic-dietary management, significantly increases weight loss in…
- Trial name
- PREDIABCOACH (NCT06477900)
- Testing
- SMS reception
- Where
- 2 sites in France, Reunion
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Down Syndrome
Qualitative Exploratory Study Among Reunionese Women and Their Partners Who Have a Child With Trisomy 21
According to data from French congenital malformation registries, the prevalence of Down Syndrome (DS) in 2017 (live births and medical termination of pregnancy (MToP)) in Reunion Island was the lowest in France (23.04 per 10,000…
- Trial name
- QUALI-21 (NCT04811534)
- Testing
- Interview
- Where
- 2 sites in Reunion
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Coronary Surgery
Uncalibrated Pulse Contour to Assess Fluid Responsiveness in Off Pump Cardiac Surgery
The goal of this observational study is to Compare the performance of uncalibrated pulse wave contour analysis compared with transesophageal echocardiography (TEE) to assess response to a vascular filling test during…
- Trial name
- UPC-OPCS (NCT06822361)
- Where
- Reunion
- Volunteers
- 55 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Cervical Surgery, Endonasal Surgery
Effect of Passive Music Therapy Via an App on Anxiety Prevention in ENT Surgery
Music therapy is a controlled method of listening to music, utilizing its physiological, psychological, and emotional effects on humans during the treatment of illness or trauma.
- Conditions
- Cervical Surgery, Endonasal Surgery, Otologic Disease, Oropharyngeal Disease
- Trial name
- MUSICORL (NCT06600919)
- Testing
- Preoperative Music Therapy Session
- Where
- Reunion
- Volunteers
- 500 people
- Sponsor
- Clinique Saint-Vincent
Idiopathic Nephrotic Syndrome
A National Prospective Cohort of Patients With Idiopathic Nephrotic Syndrome Beginning in Childhood.
Pediatric idiopathic nephrotic syndrome (INS) is a rare disease for which the optimal therapeutic strategy has not yet been defined.
- Trial name
- PIN'SNP (NCT04207580)
- Testing
- Inclusion and follow up of pediatric patients with an idiopathic nephrotic syndrome,
- Where
- 48 sites in France, Reunion
- Volunteers
- 1,180 people
- Sponsor
- University Hospital, Limoges
Sport Injury
Epidemiology of Injuries During Crossfit Practice
This study aims to precisely describe epidemiology of injuries than occur during practice of crossfit. Each participant will complete questionnaires in order to identify injuries.
- Trial name
- EPITRAUMA-CF (NCT05199220)
- Testing
- Questionnaire
- Where
- Reunion
- Volunteers
- 542 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Neurocognitive Deficit
Concordance Between Mini-Mental Stats Examination (MMSE) and an Adapted Version of the MMSE in Reunion Island Population (MMS-Run)
Illeteracy concerns more than 38% of Réunion Island's people older than 65 years old, which makes it an important risk factor for dementia and a limit to neurocognitive test's administration.
- Trial name
- MMS-R-ep (NCT05858489)
- Testing
- Mini-Mental State Examination (MMSE)
- Where
- Reunion
- Volunteers
- 61 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Stress
Impact of a Self-hyPnOsis Practice on Chronic StresS Among Caregivers of Elderly People With Loss of Autonomy at Home
In France, stress particularly affects family caregivers because of the intensive help they provide on a permanent basis to people losing their autonomy at home.
- Trial name
- POSSAID (NCT04909970)
- Testing
- Self-hypnosis, Control (Waiting list)
- Where
- Reunion
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Dialysis
Study of the Determinants of Emergency Dialysis in Reunion Island
Among patients followed by nephrologists, the frequency of emergency dialysis starts' and their social and clinical determinants are not well known, especially in Reunion Island.
- Trial name
- PEPER (NCT05305781)
- Where
- Reunion
- Volunteers
- 233 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Post-traumatic Stress Disorder
Interest of Cardiac Coherence in the Prevention of Chronic Post-traumatic Stress Disorder: Pilot Study
ThThe aim of this study is to determinate the potential benefits of a respiratory training program (cardiac coherence, CC) in patients suffering from acute stress disorder, after a potentially traumatic event.
- Trial name
- COHEPS-P (NCT04701723)
- Testing
- cardiac coherence
- Where
- Reunion
- Volunteers
- 44 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Thyroid Cancer
ESTIMation of the ABiLity of Prophylactic Central Compartment Neck Dissection to Modify Outcomes in Low-risk Differentiated Thyroid Cancer
Prospective randomized open phase III non-inferiority trial in cT1bT2N0 papillary thyroid carcinoma comparing: total thyroidectomy alone (experimental group) versus total thyroidectomy + Prophylactic Neck Dissection PND…
- Trial name
- ESTIMABL3 (NCT03570021)
- Testing
- total thyroidectomy with bilateral prophylactic central compartment (level VI) neck dissection, total thyroidectomy alone without neck dissection
- Where
- 21 sites in France, Guadeloupe and 1 more
- Volunteers
- 352 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris