Clinical trials: active, in Reunion
Non-cystic Fibrosis Bronchiectasis
Long-term Evaluation of the SIMEOX Device at Home in Non-cystic Fibrosis Bronchiectasis
Bronchiectasis is a chronic lung disease of multiple aetiologies characterised by permanent dilatation of the calibre of a territory of the bronchial tree with impaired mucociliary clearance.
- Trial name
- Home-BRAC (NCT06487273)
- Testing
- SIMEOX, Remote Physiotherapy
- Where
- 57 sites in France, Germany and 4 more
- Volunteers
- 468 people
- Sponsor
- Physio-Assist
Hereditary Heart Diseases
Stratification of Arrhythmic Risk and/or Heart Failure Risk in Patients With Hereditary Heart Disease
Sudden cardiac death (SCD) is one of the leading causes of death in developed countries. These deaths (more than 5,000 per year in France) are due to hereditary arrhythmias or cardiomyopathies.
- Trial name
- PREVENT (NCT07257289)
- Testing
- Blood sample
- Where
- 15 sites in France, Martinique and 1 more
- Volunteers
- 1,000 people
- Sponsor
- Nantes University Hospital
Tobacco Addiction
Interventional Study on Smoking Reduction in Psychiatry
The smoking rate among people with mental disorders is higher than in the general population. Greater exposure to the harmful effects of tobacco partly explains the major inequality in life expectancy observed among people with…
- Trial name
- TABAPSY (NCT06926153)
- Testing
- TABAPSY, Usual Care
- Where
- 22 sites in France, Guadeloupe and 1 more
- Volunteers
- 6,500 people
- Sponsor
- GCS-CCOMS
Glioblastoma
Diffuse Gliomas in Reunion Island: Establishment of an Epidemiological, Clinical-biological and Socio-anthropological Cohorte
To date, very little data exists on gliomas in the Réunion population, in terms of epidemiology, socio-cultural aspects, clinical or biological factors, and care pathways.
- Trial name
- GLIORUN (NCT07865195)
- Where
- Reunion
- Volunteers
- 214 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Chikungunya Virus Infection
Real-world Effectiveness, Safety & Immunogenicity of Chikungunya Vaccination: Ambispective Study in Reunion & French Guiana
In the context of the ongoing chikungunya epidemic in Réunion Island and the anticipated epidemic in French Guiana, the investigators propose an ambispective study to evaluate the real-world effectiveness, safety, and…
- Trial name
- CHIK-RE-VAC (NCT06928753)
- Testing
- IXCHIQ, VIMKUNYA
- Where
- 2 sites in French Guiana, Reunion
- Volunteers
- 1,505 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Dermatitis
HYPNOsis in the Management of Atopic Dermatitis in Children and Teenagers
Atopic dermatitis (AD) is a chronic inflammatory dermatosis, common in children. It causes pruritus and skin lesions that can have a significant impact on patients' quality of life.
- Trial name
- HypnoDA (NCT05611346)
- Testing
- Hypnosis
- Where
- Reunion
- Volunteers
- 32 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Heart Failure
The Value of a Simple Tool for the Early Detection of Decompensated Heart Failure in People Over 55 on Réunion Island: A Preliminary Study in Hospitals (DEPIST'IC-RUN)
The goal of this study is to assess the discriminatory power of a previously developed tool for detecting decompensated heart failure-which includes, in particular, clinical signs-in a population of patients hospitalized in…
- Trial name
- DEPIST'IC-RUN (NCT07673562)
- Testing
- Early Detection Questionnaire
- Where
- 3 sites in Reunion
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Diabetes type1, Diabetes Type 2
Exploration of Health Literacy in Diabetes in Reunion Island and France
The goal of this observational study is to identify the health literacy profile of diabetic patients in Reunion Island and France in order to obtain information to improve access to information, therapeutic education and to…
- Conditions
- Diabetes type1, Diabetes Type 2, Diabetes, Gestational
- Trial name
- HLQ-Diabete (NCT06437782)
- Testing
- Questionnaire completion
- Where
- 2 sites in Reunion
- Volunteers
- 1,350 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Suicide, Attempted, Suicidal Ideation
Music Against Psychological Pain in Suicide
This study compares the efficacy of music therapy associated with standard care versus the standard care alone on the psychological pain in suicidal patients.
- Trial name
- MAPPS (NCT04085848)
- Testing
- music therapy
- Where
- Reunion
- Volunteers
- 264 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Diabetes
Study of the Prevalence of Diabetes and Pre-diabetes in Réunion Island
In view of the new priority given to diabetes in Réunion and the implementation of an ambitious plan to combat the disease at regional level, which includes the identification and management of pre-diabetes, the need for…
- Trial name
- PREVADIABRUN (NCT06473584)
- Testing
- Diabetes detection
- Where
- Reunion
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Pediatric Tumor
Use of Virtual Reality in Pain Management in Pediatric Oncology
DOREVI is a monocentric randomized controlled study that will evaluate the efficacy of virtual reality helmets for pain prevention during invasive care on 78 oncologic pediatric patients.
- Trial name
- DOREVI (NCT05592132)
- Testing
- Virtual reality headset
- Where
- Reunion
- Volunteers
- 74 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Well Being
Validation of the Shared Happiness Index in Multidisciplinary Primary Care Practices ( Be aPi )
Multi-professional primary care practices (Maisons de Santé Pluriprofessionnelles, MSP) have expanded widely in France over the last decade to respond to increasing healthcare needs, uneven distribution of physicians, and…
- Trial name
- Be aPi (NCT07431372)
- Where
- Reunion
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Alzheimer s Disease, Vascular Cognitive Impairment
Adaptation of the Mini-Mental State Examination (MMSE) for the Reunion Island Population
The Mini-Mental State Examination (MMSE) is the most widely used cognitive screening and monitoring test for neurocognitive disorders in current clinical practice.
- Trial name
- MMSE-RUN (NCT07251647)
- Testing
- MMSE-RUN and MMSE GRECO
- Where
- 7 sites in Reunion
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Neurological Complication
Transcranial Doppler, Optic Nerve Envelope Diameter and Quantitative Pupillometry Measurements
Non-invasive neuromonitoring tools such as transcranial doppler, optic nerve envelope diameter measurement and quantitative pupillometry are routinely used in acute brain injured patients as part of multimodal neuromonitoring…
- Trial name
- DOPPLER (NCT05843214)
- Testing
- Non-invasive neuromonitoring evaluation (transcranial doppler, optic nerve envelope diameter and quantitative pupillometry)
- Where
- Reunion
- Volunteers
- 230 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Gene Mutation-Related Cancer, Genetic Predisposition
COsegregation of VARiants in Panel of Genes
The aim of the COVAR project is to achieve reliable classification of as many variants of interest as possible from the French OncoGenetics Database (FrOG, https://frog-db.fr/) in order to use them for the genetic counseling.
- Trial name
- COVAR (NCT01689584)
- Testing
- salivary kit
- Where
- 62 sites in France, Guadeloupe and 3 more
- Volunteers
- 11,000 people
- Sponsor
- Institut Curie
Kidney Cancer
UroCCR Database: French Research Network for Kidney Cancer -UroCCR
Kidney cancer management has become increasingly complex with the diversification of treatment options and the integration of multidisciplinary care.
- Trial name
- UroCCR (NCT03293563)
- Testing
- Radical nephrectomy versus partial nephrectomy (according surgeon judgement)
- Where
- 68 sites in Belgium, France and 2 more
- Volunteers
- 30,000 people
- Sponsor
- University Hospital, Bordeaux
Post Extubation Respiratory Failure
Non-Invasive Ventilation Versus High-flow Nasal Oxygen in Intensive Care Units
In intensive care units (ICUs), around 20% of patients experience respiratory failure after planned extubation. Nearly 40-50% of them eventually require reintubation with subsequently high mortality rates reaching 30-40%.
- Trial name
- VENTILO (NCT05686850)
- Testing
- High-Flow Oxygen, Non invasive ventilation
- Where
- 47 sites in Belgium, France and 3 more
- Volunteers
- 670 people
- Sponsor
- Poitiers University Hospital
Cystic Fibrosis
Pathogenicity of Species of the Achromobacter Genus in Patients From Reunion Island With Cystic Fibrosis
The pathogenicity of Achromobacter bacteria is not yet well established, but studies show a decline in respiratory function and an increase in mortality associated with chronic colonisation, making it possible to classify the…
- Trial name
- ACHROMO-MUCO (NCT06371261)
- Testing
- Biological analyses
- Where
- 2 sites in Reunion
- Volunteers
- 17 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Pseudomonas Infections, Pseudomonas Aeruginosa
Antimicrobial Therapy for Difficult-to-treat Pseudomonas Aeruginosa
The primary objective of the ADDICT study is to assess and compare the clinical efficacy of available options for antimicrobial therapy (new beta-lactam/beta-lactamase inhibitor combination, cefiderocol or older agents such as…
- Conditions
- Pseudomonas Infections, Pseudomonas Aeruginosa, Prognosis, Drug Resistance, Multiple, Bacterial
- Trial name
- ADDICT (NCT06738771)
- Where
- 48 sites in France, Reunion
- Volunteers
- 600 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Esophageal Atresia
Long Term Outcome of Easophageal Atresia : Transmics Profiles in Adolescence
Oesophageal atresia (OAEA), a malformation of the oesophagus present from birth, is characterized by the interruption of the continuity of the oesophagus, which then ends in a cul-de-sac.
- Trial name
- TransEAsome (NCT05995171)
- Testing
- Questionnaire
- Where
- 33 sites in France, Martinique and 1 more
- Volunteers
- 300 people
- Sponsor
- University Hospital, Lille